• Proceedings of the Korean Society of Computer Information Conference
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• 2019.07a
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• pp.395-396
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• 2019

표적 암세포 또는 마이크로미터 단위 이하의 미세 입자의 검출하기 위해 다양하게 사용되는 유세포분석기는 레이저와 같은 특정 파장의 광원 및 파장대별 선택이 가능한 필터, 고성능 광탐지기로 구성되어있다. 이 분석기는 표적물질의 광학적 산란특징에 기인하여 입상도와 크기, 농도 등의 물리적 정보제공이 가능하나, 고가이며 사용자의 요구에 따른 다양한 광원 및 필터의 선택이 제한적이라는 단점을 가지고 있다. 본 논문에서는 상용화된 마이크로컨트롤러, 발광다이오드, 광검출기와 필름형식의 광학필터를 사용하여 저가의 표적 암세포 검출기를 개발하고자 한다. 또한, 3D 프린터를 사용하여 사용자의 필요에 따른 설계변화와 이동이 용이하므로, 공간의 제약을 받지 않고 다양한 분야에 적용이 가능하다. 제안된 검출기의 광감지 수치는 세포의 농도에 따라 높은 선형성을 보였으며, 세포수량기를 사용한 결과 값과 비교하였을 때 무의미한 통계학적 차이를 보였다.

• Korean Journal of Cognitive Science
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• v.24 no.4
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• pp.365-391
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• 2013

Negative repetition effect (NRE) refers to the phenomenon that the accuracy of report is impaired when a target was flanked by the same distractor than when by alternative distractor. To probe the nature of NRE, this study introduced attention window(s) indicating the positions where a target might be presented, and non-attention window(s) where a target could not be presented. Attention windows are supposed to help participants detect targets readily. Two among three positions are indicated by attention windows in Exp. 1, and a single large attention window encompassing central two positions among four positions was used in Exp. 2, and either large or small attention window was used depending on the number of target candidates in Exp. 3. In the result of three experiments, NREs were consistently observed when both positions of a target and a distractor were indicated by previous attention windows. However, NREs (including its tendency) and its opposite, PREs were observed when a distractor was presented in the non-attention position, depending on its distance from the target and the size of attention window. It seems that this pattern of repetition effects is hard to be explained by repetition blindness hypothesis (Kanwisher, 1991), positional uncertainty hypothesis (Keren & Boer, 1985), and inhibitory attention capture hypothesis (Kwak et al., 1993). Instead it was proposed that shifting of spatial attention should be considered accordingly with the structure of stimulus display. The promising role of this task was discussed in studying the relation of attention and perception.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.22 no.10
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• pp.981-989
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• 2011

In this paper, we performed radar target classification for the five scale models using ultra-wideband measured signal. In order to compare the performance, the 2 GHz(2~4 GHz), 4 GHz(2~6 GHz), and 6 GHz(2~8 GHz) bandwidth were used. Short time Fourier transform(STFT) and continuous wavelet transform(CWT) are used for target feature extraction. Extracted feature vectors are used as input for the multi-layerd perceptron(MLP) neural network classifier. The results show that as the bandwidth is wider, the performance is better.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.34 no.9C
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• pp.863-870
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• 2009

Bilateral filter (BF) is a nonlinear filter for sharpness enhancement and noise removal. The BF performs the function by the two Gaussian filters, the domain filter and the range filter. To apply the BF to infrared (IR) small target detection, the standard deviation of the two Gaussian filters need to be changed adaptively between the background region and the target region. This paper presents a new BF with the adaptive standard deviation based on the analysis of the edge component of the local window, also having the variable filter size. This enables the BF to perform better and become more suitable in the field of small target detection Experimental results demonstrate that the proposed method is robust and efficient than the conventional methods.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.48 no.5
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• pp.55-63
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• 2011

This paper describes new moving target detection technique combining two algorithms to detect targets and reject clutters in video frame images for surveillance system: One obtains the region of moving target using phase correlation method using $N{\times}M$ sub-block images in frequency domain. The other uses adaptive threshold using learning weight for extracting target candidates in subtracted image. The block region with moving target can be obtained using the characteristics that the highest value of phase correlation depends on the movement of largest image in block. This technique can be used in camera motion environment calculating and compensating camera movement using FFT phase correlation between input video frame images. The experimental results show that the proposed algorithm accurately detects target(s) with a low false alarm rate in variety environment using the receiver operating characteristics (ROC) curve.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.35 no.11B
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• pp.1738-1747
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• 2010

This report shows the analysis and design of tactical decision automation procedure and the result of core algorithm. Expecially scheme of analysis and design includes result of tactical decision supporting procedure analysis for target engagement to fire in refer to AFATDS. Tactical decision automation procedure has three phases like target analysis, target priority, fire unit decision, fire method and attack method. Target analysis creates base information to decide priorities and attack methods through target activity, size and protection status. Target priority and fire unit decision judge target priority and fire unit with unit status and operation mission basis of target priority. Fire unit and Attack method decide fire style according to the kind of fire and ammunition for effective firing achievement. Finally, we show the effective tactical decision automation procedure through making the algorithm of priority and air control.

• Radiation Oncology Journal
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• v.28 no.3
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• pp.177-183
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• 2010

Purpose: Simulation using computed tomography (CT) is now widely available for radiation treatment planning for breast cancer. It is an important tool to help define the tumor target and normal tissue based on anatomical features of an individual patient. In Korea, most patients have small sized breasts and the purpose of this study was to review the margin of treatment field between conventional two-dimensional (2D) planning and CT based three-dimensional (3D) planning in patients with small breasts. Materials and Methods: Twenty-five consecutive patients with early breast cancer undergoing breast conservation therapy were selected. All patients underwent 3D CT based planning with a conventional breast tangential field design. In 2D planning, the treatment field margins were determined by palpation of the breast parenchyma (In general, the superior: base of the clavicle, medial: midline, lateral: mid - axillary line, and inferior margin: 2 m below the inframammary fold). In 3D planning, the clinical target volume (CTV) ought to comprise all glandular breast tissue, and the PTV was obtained by adding a 3D margin of 1 cm around the CTV except in the skin direction. The difference in the treatment field margin and equivalent field size between 2D and 3D planning were evaluated. The association between radiation field margins and factors such as body mass index, menopause status, and bra size was determined. Lung volume and heart volume were examined on the basis of the prescribed breast radiation dose and 3D dose distribution. Results: The margins of the treatment field were smaller in the 3D planning except for two patients. The superior margin was especially variable (average, 2.5 cm; range, -2.5 to 4.5 cm; SD, 1.85). The margin of these targets did not vary equally across BMI class, menopause status, or bra size. The average irradiated lung volume was significantly lower for 3D planning. The average irradiated heart volume did not decrease significantly. Conclusion: The use of 3D CT based planning reduced the radiation field in early breast cancer patients with small breasts in relation to conventional planning. Though a coherent definition of the breast is needed, CT-based planning generated the better plan in terms of reducing the irradiation volume of normal tissue. Moreover it was possible that 3D CT based planning showed better CTV coverage including postoperative change.

• Progress in Medical Physics
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• v.15 no.2
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• pp.84-93
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• 2004

Stereotactic radiosurgery (SRS) is a technique that delivers a high dose to a target legion and a low dose to a critical organ through only one or a few irradiations. For this purpose, many mathematical methods for optimization have been proposed. There are some limitations to using these methods: the long calculation time and difficulty in finding a unique solution due to different tumor shapes. In this study, many clinical target shapes were examined to find a typical pattern of tumor shapes from which some possible ideal geometrical shapes, such as spheres, cylinders, cones or a combination, are assumed to approximate real tumor shapes. Using the arrangement of multiple isocenters, optimum variables, such as isocenter positions or collimator size, were determined. A database was formed from these results. The optimization procedure consisted of the following steps: Any shape of tumor was first assumed to an ideal model through a geometry comparison algorithm, then optimum variables for ideal geometry chosen from the predetermined database, followed by a final adjustment of the optimum parameters using the real tumor shape. Although the result of applying the database to other patients was not superior to the result of optimization in each case, it can be acceptable as a plan starling point.

• Journal of the Korean Chemical Society
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• v.57 no.4
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• pp.493-498
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• 2013

Liposomes, which can deliver payload at target site, have been studied as drug carrier. However, conventional liposomes have limitation for drug release at target site. Therefore, we developed hydroxyapatite (HA) coated ultrasound sensitive liposomes to increase drug release at target site and to enhance stability in blood stream. Control liposome was prepared using hydrogenated soy phosphatidylcholine (HSPC) and cholesterol, and then we assessed HA coating on the surface of control liposomes using calcium acetate, phosphoric acid, and 25% ammonium solution. Doxorubicin was used as a model drug. Size of HA coated liposomes was 120 nm and encapsulation efficiency of doxorubicin in liposomes was up to 95%. Size of HA coated liposomes are not changed in 30% serum solution, however, the control liposomes was 1.4 fold increased. After ultrasound triggered drug release from liposomes, intracellular efficiency of drug released from HA coated liposomes was 3 fold increased compared to control liposomes. In this study, we developed ultrasound sensitive liposomes to enhance drug release, which will be applied in controlled drug release at disease site.

• 전자공학회논문지 IE
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• v.43 no.2
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• pp.54-62
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• 2006

In this paper, a new stereo object tracking system using the disparity motion vector is proposed. In the proposed method, the time-sequential disparity motion vector can be estimated from the disparity vectors which are extracted from the sequence of the stereo input image pair and then using these disparity motion vectors, the area where the target object is located and its location coordinate are detected from the input stereo image. Basing on this location data of the target object, the pan/tilt embedded in the stereo camera system can be controlled and as a result, stereo tracking of the target object can be possible. From some experiments with the 2 frames of the stereo image pairs having $256\times256$ pixels, it is shown that the proposed stereo tracking system can adaptively track the target object with a low error ratio of about 3.05 % on average between the detected and actual location coordinates of the target object.