• Title/Summary/Keyword: 표기 방법

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Studies on Mass Production of Intracellularly-Produced Secondary Metabolite, Cyclosporin A by Use of Immobilized Fungal Cells in Stirred-Tank Immobilized Perfusion Reactor System(IPRS) (교반식 perfusion 생물반응기(IPRS)에서 고밀도 고정상 곰팡이 세포를 이용한 세포내 축적 이차대사산물인 Cyclosporin A 대량생산에 관한 연구)

  • 전계택;이태호장용근
    • KSBB Journal
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    • v.11 no.1
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    • pp.22-29
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    • 1996
  • Immobilized bioprocess was carried out for continuous production of cyclosporin A (CyA) produced intracellularly as a secondary metabolite by a filamentous fungus, Tolypocladium inflatum. Immobilization procedure for entrapping conidiospores of the producer was significantly simplified by use of a modified immobilization technique. A newly-designed immobilized perfusion reactor system (IPRS) showed good process benefits as demonstrated by the role of the high density immobilized cells as an efficient biomass generator, continuously supplying highly active CyA-producing free cells (1.0g/$\ell$/hr) even at very high dilution rate ($0.1hr^{-1}$). IPRS bioprocess was possible since efficient decantor system developed in our laboratory separated the sloughed-off free cells from the immobilized biomass effectively, thus overcoming wash-out phenomenon frequently encountered in continuous free cell cultures. Furthermore the released-free cells remaining in the bulk solution did not appear to cause substrate mass transfer limitation which was often experienced in suspended mycelial fungal cell fermentations. The primary reason for this was that the suspension broth of the IPRS mainly consisted of roundshaped short mycelial fragments and conidiospores, still remaining Newtonian even at high cell density. In parallel with IPRS bioprocess development, other key factors to be considered necessarily for significant increase in CyA productivity would be strain improvement and medium optimization for the immobilized cells.

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Main Features of Leather Armor from the Joseon Dynasty in the National Museum of Korea (국립중앙박물관 소장 조선시대 피갑(皮甲)의 특징에 관한 고찰)

  • Hwang, Jinyoung
    • Conservation Science in Museum
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    • v.20
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    • pp.61-76
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    • 2018
  • The National Museum of Korea conducted conservation treatmenton the armor in its collection for the purposes of public display and appropriate preservation. This was preceded by a literature study on the types and features of the armor in order to collect basic data for secure and accurate conservation treatment. The literature study found that during the Joseon dynasty, armor was named in reflection of precise details including the color, material, status of the wearer, and even the certain parts of a suit of armor. In general, the name of armor includes the details in the order of color, underlying textile, and scale material (e.g., iron, leather). The former part of the name presents the features of the garment and the latter part refers to the material of the scales or the status of the wearer. The study also found that main materials used in armor include textiles, leather, and metal, and armor can be classified by the materials of the scales-e.g., metal armor (鐵甲), leather armor (皮甲), paper armor (紙甲), paper-and-fabric armor (淹心甲), silk armor (緞甲). Joseon-period armor can also be classified into four types according to its structure and the method of wearing, and overcoat(袍)-style armor was the most widely used in the period following the Japanese Invasion of Joseon (1592-1598) through the late nineteenth~early twentieth century. Overcoat-style armor was commonly worn by infantry, and the four examples of armor with leather scales at the National Museum of Korea belong to this category.

A Hierarchical Bitmap-based Spatial Index for Efficient Spatial Query Processing on Air (무선환경에서 효과적인 공간질의 처리를 위한 계층적 비트맵 기반 공간 색인)

  • Song, Doo-Hee;Park, Kwang-Jin
    • Journal of Internet Computing and Services
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    • v.12 no.6
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    • pp.43-51
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    • 2011
  • The recent development of the technology for wireless mobile computing and applied technology for location-based services has made it possible to support query processing faster than that in the past. However, some technological limitations on hardware and software still exist. The most critical aspects of query processing are accuracy and speed. For improving the accuracy, it is required that detailed information on the data involved in query processing be saved. In this case, the amount of information on the data increases, which decreases the speed. On the other hand, for increasing the speed, it is necessary to reduce the broadcast cycle, which enables rapid data acquisition as desired. In this case, because of insufficient index information, the listen time for the client increases, which may cause unnecessary energy consumption. Therefore, a trade-off occurs between the accuracy and speed. This paper proposes a hierarchical bitmap-based spatial index (HBI) as a solution for the aforementioned problems. HBI describes an object with 0 and 1 on the Hilbert curve map. It reduces the broadcast cycle by decreasing the index size on the basis of bit information and tree structure. Therefore, it is able to shorten the listen time and query processing time. In addition, HBI enables the detection of the locations of all the objects so that it is possible selectively listen to a broadcast. A performance evaluation of the proposed technique demonstrates that it is excellent.

Rheological Characteristics and Molecular Weight of Ammonium-Sulfate Fractions of Tara Gum (염석법에 의한 타라검 분획들의 분자량 및 리올로지 특성)

  • Kim, Kyeong-Yee
    • Korean Journal of Food Science and Technology
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    • v.47 no.3
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    • pp.293-298
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    • 2015
  • This study aimed at characterizing the rheological properties and molecular weight of tara gum fractionated with ammonium sulfate. Tara gum was separated into six fractions (F1-F6) at different concentrations of ammonium sulfate, ranging from 12.21 to 28.67% (w/w). The yield of the tara gum fractions ranged between 4.98 and 17.47%, and their intrinsic viscosity ranged from 9.38 to 12.44 dL/g. The highest values of Huggins coefficient (k') and viscosity-molecular mass were observed in fraction F3. The shear viscosity of the tara gum fractions was measured by a cone-plate viscometer, clearly showing shear thinning behavior. Size-exclusion chromatography results showed that the molecular weight ranged between 635.42 and 776.71 kg/mol, and the F3 fraction exhibited higher values of molecular weight.

The History of Bibimbap (비빔밥의 역사)

  • Chung, Kyung Rhan
    • The Journal of the Korea Contents Association
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    • v.15 no.11
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    • pp.603-615
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    • 2015
  • The history of Bibimbap, Korea representative traditional foods, was distorted by some humanities scholars as follows : First literature on Bibimbap is Siujonseo(是議全書) in 1890 and origin word of Bibimbap is Koldongban(骨董飯). Such discussions are totally non-scientific and not true. Bibimbap was recorded as Hondonban(混沌飯) in Kijaejapki 500 years ago and Koldongban(骨董飯) in Sunghojeonjip(星湖全集) and Bubuiban, which mean the people in Korea had the Bibimbap often thousands years ago, i.e. around 500 years before literature. Hangul name of Bibimbap as '브뷔움' was written firstly in Mongyupyun(夢喩篇) in 1810, not Siujonseo(是議全書). Hangul names of Bibimbap were written as '부뷔음, 부빔밥, 부?밥, 부뷘밥, 부뷔엄밥, 부뷔음밥'. Koldongban is only the chinese character which write the real existent Bibimbap real name of Bibimbap is just bibimbap. People in 500 years called Bibimbap as Bibimbap, but wrote it as Koldongban, Hondonban and Bubiban because they had to write the things in Chinese character.

Performance Comparison of State-of-the-Art Vocoder Technology Based on Deep Learning in a Korean TTS System (한국어 TTS 시스템에서 딥러닝 기반 최첨단 보코더 기술 성능 비교)

  • Kwon, Chul Hong
    • The Journal of the Convergence on Culture Technology
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    • v.6 no.2
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    • pp.509-514
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    • 2020
  • The conventional TTS system consists of several modules, including text preprocessing, parsing analysis, grapheme-to-phoneme conversion, boundary analysis, prosody control, acoustic feature generation by acoustic model, and synthesized speech generation. But TTS system with deep learning is composed of Text2Mel process that generates spectrogram from text, and vocoder that synthesizes speech signals from spectrogram. In this paper, for the optimal Korean TTS system construction we apply Tacotron2 to Tex2Mel process, and as a vocoder we introduce the methods such as WaveNet, WaveRNN, and WaveGlow, and implement them to verify and compare their performance. Experimental results show that WaveNet has the highest MOS and the trained model is hundreds of megabytes in size, but the synthesis time is about 50 times the real time. WaveRNN shows MOS performance similar to that of WaveNet and the model size is several tens of megabytes, but this method also cannot be processed in real time. WaveGlow can handle real-time processing, but the model is several GB in size and MOS is the worst of the three vocoders. From the results of this study, the reference criteria for selecting the appropriate method according to the hardware environment in the field of applying the TTS system are presented in this paper.

The Bibliographical Investigation of the Lettuce (상추에 대한 사상의학적(四象醫學的) 고찰(考察) -백거, 와거, 고거, 고채(苦菜)를 중심으로-)

  • Kim, Jong-dug;Koh, Byung-hee
    • Journal of Sasang Constitutional Medicine
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    • v.11 no.2
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    • pp.341-359
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    • 1999
  • In the medical science of 'Sa-sang', a constitutional examination(diagnosis) and a medical treatment are important, however a dietary cure is considered as very important at the medical prevention and treatment. But there has been a confusion due to the different view concerning the constitutional foods in between scholars. There it is necessary for us to bring up the theoretical basis of the 'Sa-sang' constitutional - dietary cure by menas of the bibliographical study in relation to a historic, characteristics, efficiency of the major foods.

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Component-Z: A Formal Specification Language Extended Object-Z for Designing Components (Component-Z: Object-Z를 확장한 컴포넌트 정형 명세 언어)

  • 이종국;신숙경;김수동
    • Journal of KIISE:Software and Applications
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    • v.31 no.5
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    • pp.677-696
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    • 2004
  • Component-based software engineering (CBSE) composes reusable components and develops applications with the components. CBSE is admitted to be a new paradigm that reduces the costs and times to develop software systems. The high quality of component designs can be assured if the consistency and correctness among the elements of a component are verified with formal specifications. Current formal languages for components include only some parts of contracts between interfaces, structural aspects and behavioral aspects of component, component-based system, component composition and variability. Therefore, it is not adequate to use current formal languages in all steps of a component design process. In this paper, we suggest a formal language to specify component designs Component-Z. Component-Z extends Object-Z, adds new notations to specify components. It can be possible to specify interfaces, the inner structure of a component, inner workflows, and workflows among interfaces with Component-Z. In addition, Component-Z provides the notations and semantics to specify variability with variation points, variants and required interfaces. The relation between interfaces and components is defined with mapping schemas. Parallel operator is used to specify component composition. It can be possible to describe deployed components with the specifications of component-based systems. Therefore, the formal specification language proposed in this paper can represent all elements to design components. In the case study, we specify an account management system in a bank so that we show that Component-Z can be used in all steps of component design.

필름 스피커 적용을 위한 PZT/polymer 복합체의 후막 제조 및 압전 특성 평가

  • Son, Yong-Ho;Eo, Sun-Cheol;Kim, Seong-Jin;Gwon, Seong-Yeol;Gwon, Sun-Yong
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2007.11a
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    • pp.346-346
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    • 2007
  • 압전세라믹 재료는 현재 압전 변압기, actuator, transducer, sensor, speaker 등에 광범위하게 이용이 되고 있다. 이 중에서 압전세라믹 소결체를 이용한 스피커의 제조는 가공이 까다롭고, 대형의 크기로 제작 시 소자가 깨지는 등의 많은 제약을 받고 있으며, 저음 특성이 떨어져 응용 범위가 한정되어 있다. 따라서 최근에는 이러한 단점을 극복하기 위하여 세라믹/고분자 복합체를 이용한 필름 스피커를 제작하고자 시도하고 있다. 이러한 세라믹/고분자 0-3형 압전 복합체를 이용할 경우, 제품의 경량화를 실현할 수 있고, 크기나 환경의 영향을 거의 받지 않으므로, 고기능성 스피커로의 응용에 적합할 것으로 보인다. 따라서 본 연구에서는 PZT계의 세라믹와 PVDF, PVDF-TrFE, Polyester, acrylic resin 등의 여러 고분자 물질과의 복합체를 제조하여 압전특성을 평가하였다. 본 실험은 먼저 $(Pb_{1-a-b}Ba_aCd_b)(Zr_xTi_{1-x})_{1-c-d}(Ni_{1/3}Nb_{2/3})_c(Zn_{1/3}Nb_{2/3})_dO_3$ (이하 PZT라 표기)의 최적화 조성을 선택하여, $1050^{\circ}C$에서 소결된 분말을 48시간 ball milling방법 로 약 $1{\mu}m$ 크기로 분쇄하였다. 고분자 물질들은 알맞은 용제들을 선택하여 녹였다. 그 다음 소결된 PZT분말과 고분자를 50:50, 60:40, 65:35, 70:30등의 무게 분율로 혼합하고, 분산제, 소포제 등을 첨가하여 3단 roll mill을 이용하여 충분히 분산시켜 페이스트 (Paste)를 제조하였다. 제조된 페이스트를 ITO가 코팅된 PET필름 위에 스크린 프린팅 법을 사용하여 인쇄하여 $120^{\circ}C$에서 5분간 건조하였다. 코팅된 복합체의 두께는 약 $80{\mu}m$ 정도로 측정되었다. Ag 페이스트를 이용한 상부 전극 형성에도 스크린 프린팅 법을 적용하였다. 이를 $120^{\circ}C$에서 4 kV/mm의 DC 전계로 분극 공정을 수행한 후 전기적 특성을 평가하였다. 유전특성을 조사하기 위해서 LCR meter (EDC-1620)를 사용하였고, 시편의 결정구조는 XRD (Rigaku; D/MAX-2500H)을 통해 분석하였으며, 전자현미경(SEM)을 이용하여 미세구조를 분석하였다. 압전 전하상수$(d_{33})$ 값은 APC 8000 모델을 이용하여 측정하였다. PZT의 혼합비가 증가할수록 비유전율 및 압전 전하 상수 등의 전기적 특성이 증가되었다. 또 여러 고분자 물질 중에서 PVDF-TrFE 수지가 가장 우수한 특성을 보였다. 이는 PVDF-TrFE 수지가 압전성을 나타내기 때문인 것으로 판단되었다.

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A Study of the Wall Repair Record and Construction Technology of Geungnakbojeon Hall at Muwisa Temple in Gangjin (강진 무위사 극락보전의 벽체 수리 기록과 시기별 시공기술 고찰)

  • Hong, Eunki
    • Korean Journal of Heritage: History & Science
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    • v.53 no.2
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    • pp.140-155
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    • 2020
  • The purpose of this study is to examine historical wall repair details through analysis of repair data and administrative documents of the Paradise Conservation of Gangjin Muwisa Temple. In addition, the purpose of the project is to examine the differences and commonalities between the materials and construction technology used in the building's walls. The data for repair work conducted in 1935, 1956, and 1982~3 was analyzed and the results of the research were as follows. First, data for the wall construction conducted in 1935 during the dismantling repair showed that the interior structure of the wall was found to follow that of the original, but the first, second, and final layers used different materials. The composition material of the wall consisted of clay, lime and sand, the second layer used sand and plaster, and the last layer used plaster and seaweed paste. Second, the structure of the wall interior, which was found during the 1956 repairs, consisted of wood woven horizontally and vertically. It was confirmed that this had been installed diagonally using a rope. Third, the 1982~3 repair work confirmed that the wall's interior construction conformed to the original method. The lime-sand wall was formed by mixing slacked lime, sand, soil, fodder, and seaweed grass. Fourth, when the various repairs are considered as a whole, it is clear that the interior structure of the wall was made more than 1900 years ago, and the material used in the wall changed in 1935. Fifth, the materials used for each repair differed, but each project had a common view of cultural heritage repair principles in sections that stated the significance of each project.