• Journal of the Korean Applied Science and Technology
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• v.39 no.1
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• pp.18-26
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• 2022

The present study aimed to evaluate the effect of Eucommia ulmoides extracts on rheumatoid arthritis biomarker in a CIA-induced DBA/1 mice. For evaluation, Eucommia ulmoides extracts was administered orally at dose of 100 mg/kg/day for 4 weeks after production of an animal model of rheumatoid arthritis and we confirmed the treatments' effects based on serum biomarker, radiological, structural parameter analysis. Compared to the negative control group, the Eucommia ulmoides extracts treatments significantly reduced the serum level of inflammation and immunoglobulin markers (i.e., TNF-α, IgG, and hs-CRP), and significantly decreased the monocyte count of white blood cells. Furthermore, the Eucommia ulmoides extracts treatments effectively preserved the joint destruction, and little the joint deformation. Moreover, compared to the negative control group, the Eucommia ulmoides extracts treatments increased the bone volume, and significantly decreased bone inflammation. The results indicate that the Eucommia ulmoides extracts improved rhrumatoid arthritis symptoms. Thus, the Eucommia ulmoides extracts may be a novel therapeutic option for the management of rheumatoid arthritis.

• Proceedings of the Korea Water Resources Association Conference
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• 2022.05a
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• pp.268-268
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• 2022

지진해일은 발생빈도는 높지 않지만, 한 번 발생하게 되면 막대한 피해를 일으킬 수 있다. 우리나라에서는 1,900년대 4건의 지진해일이 기록되었으며, 이로 인해 동해안 및 남해안 등에 인명피해 및 재산피해가 발생하였다. 또한 2011년 동일본 지진해일로 인해 후쿠시마 원자력 발전소 변전설비가 침수됨에 따라 냉각수 공급이 중단되고 방화벽이 파괴되어 방사능이 누출되어 큰 피해로 연결되었다. 이러한 피해를 저감하기 위해 지진해일 수치해석과 확률론적 분석방법 등 다양한 방법을 활용한 연구가 국내외 적으로 활발히 수행되고 있다. 본 연구는 확률분포기반 지진해일고 예측모델 개발을 위해 수치해석을 수행하여 지진해일고(tsunami heights)를 산출하고 결과값에 대한 적절한 확률분포 분석을 실시하는 것이다. 지진해일고는 원자력발전소에서 취수구를 통한 냉각수 공급가능 여부를 판단하기 위해 최대 지진해일고(maximum tsunami height)와 최저 지진해일고(minimum tsunami height)로 구분하였다. 지진해일 수치해석은 지진원(단층매개변수) 조사, 조사된 지진원 중 지진해일 수치해석 case 선정을 위한 파향선추적기법(wave ray tracing) 수행, 선정된 지진원에 대해 로직트리(logic tree) 기법 적용, 로직트리를 적용한 지진원 case에 대한 수치해석 순서로 수행하였다. 수치해석을 통해 산출된 최대 및 최저 지진해일고 자료를 기반으로 확률분포형을 선정하기 위하여 확률분포별 적합성 평가를 실시하였다. 선정된 분포를 기준으로 처오름 및 처내림높이와 관련된 다양한 변수간의 의존관계를 파악하였다. 향후, 파악된 의존관계를 기반으로 예측모델을 개발하여 수치해석 결과와 연계함으로써 국내에 적용할 수 있는 확률론적 지진해일재해도를 제시할 수 있을 것으로 판단된다.

• Journal of the Korean Society of Hazard Mitigation
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• v.10 no.3
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• pp.133-145
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• 2010

This study analyzed the characteristics of sediment produce by landslide triggered by rainfall. One-dimensional unsaturated groundwater model and infinite slope stability analysis were used to estimate the behavior of soil moisture and slope stability according to rainfall, respectively. Slope stability analysis was performed considering on soil depth and characteristics of trees. As the results considering on recovery of the failed slopes, much amount of sediment was produced in 1963, 1970, and 2002. As the results of verification of simulation results using Landsat 5 TM images, we can find differences of landslide location between the results from model and satellite images. These differences can be caused by uncertainties of the rough parameters in the model. However, in the case that Obong-dam basin was divided into two subbasin, Wangsan-chun and Doma-chun basin, the results of each subbasin show errors around 20%. And only 4% of error occurred in the case of comparing landslide area on the entire Obong-dam basin. These errors seem insignificant considering on the errors which can be caused from the analyses in this study such as estimation of sediment produce, soil cover classification, and estimation of landslide area.

• Journal of the Society of Disaster Information
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• v.14 no.3
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• pp.379-386
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• 2018

Purpose: This study was to the fragility evaluation of I-shape curved beam structure subjected to strong ground motions including Gyeongju and Pohang earthquakes Method: In particular, to conduct the analytical model, ABAQUS and ANSYS platform was used in this study. Furthermore, the analytical model using 3D Finite Element Model (FEM) was validated, in comparison to the theoretical solutions at the location of 025L, 05L, and 0.75L in static loading condition. In addition, in order to evaluate the seismic fragility of the curved beam structure, 20 seismic ground motions were selected and Monte-Carlo Simulation was used for the empirical fragility evaluation from 0.2g to 1.5g. Result: It was interesting to find that the probability of the system failure was found at 0.2g, as using 190 MPa limit state and the probability of the failure using 390 MPa limit state was starting from 0.6g. Conclusion: This study showed the comparison of the theoretical solution with analytical solution on I-shaped curved beam structures and it was interesting to note that the system subjected to strong ground motions was sensitive to high frequency earthquake. Further, the seismic fragility corresponding to the curved beam shapes must be evaluated.

• Journal of the Society of Disaster Information
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• v.17 no.4
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• pp.747-754
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• 2021

Purpose: Seismic safety evaluation of a curved bridge must be performed since the curved bridges exhibit the complex behavior rather than the straight bridges, due to geometrical characteristics. In order to conduct the probabilistic seismic assessment of the curved bridge, Seismic fragility evaluation was performed using the uncertainty of the steel material properties of a curved bridge girde, in this study. Method: The finite element (FE) model using ABAQUS platform of the curved bridge girder was constructed, and the statistical parameters of steel materials presented in previous studies were used. 100 steel material models were sampled using the Latin Hypercube Sampling method. As an input ground motion in this study, seismic fragility evaluation was performed by the normalized scale of the Gyeongju earthquake to 0.2g, 0.5g, 0.8g, 1.2g, and 1.5g. Result: As a result of the seismic fragility evaluation of the curved girder, it was found that there was no failure up to 0.03g corresponding to the limit state of allowable stress design, but the failure was started from 0.11g associated with using limit state design. Conclusion: In this study, seismic fragility evaluation was performed considering steel materials uncertainties. Further it must be considered the seismic fragility of the curved bridge using both the uncertainties of input motions and material properties.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.32 no.1A
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• pp.11-18
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• 2012

This paper deals with the numerical determination of the stress intensity factors of cracked aluminum plates under the mixed mode of $K_I$ and $K_{II}$ in glass-epoxy fiber reinforced composites. For the stress intensity factors, two different models are reviewed such as VCCT and two-step extension method. The p-convergent partial layerwise model is adopted to determine the fracture parameters in terms of energy release rates and stress intensity factors. The p-convergent approach is based on the concept of subparametric element. In assumed displacement field, strain-displacement relations and 3-D constitutive equations of a layer are obtained by combination of 2-D and 1-D higher-order shape functions. In the elements, Lobatto shape functions and Gauss-Lobatto technique are employed to interpolate displacement fields and to implement numerical quadrature. Using the models and techniques considered, effects of composite laminate configuration according to inclined angles and adhesive properties on the performance of bonded composite patch are investigated. In addition to these, the out-of-plane bending effect has been investigated across the thickness of patch repaired laminate plates due to the change of neutral axis. The present model provides accuracy and simplicity in terms of stress intensity factors, stress distribution, number of degrees of freedom, and energy release rates as compared with previous works in literatures.

• Journal of the Korea Concrete Institute
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• v.16 no.6 s.84
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• pp.841-850
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• 2004

The modeling of uplift pressure within dam, on the foundation on which it was constructed, and on the interface between the dam and foundation is a critical aspect in the analysis of concrete gravity dams, i.e. crack stability in concrete dam can correctly be predicted when uplift pressures are accurately modelled. Current models consider a uniform uplift distribution, but recent experimental results show that it varies along the crack faces and the procedures for modeling uplift pressures are well established for the traditional hand-calculation methods, but this is not the case for finite element (FE) analysis. In large structures, such as dams, because of smaller size of the fracture process zone with respect to the structure size, limited errors should occur under the assumptions of linear elastic fracture mechanics (LEFM). In this paper, the fracture behaviour of concrete gravity dams mainly subjected to uplift Pressure at the crack face was studied. Triangular type, trapezoidal type and parabolic type distribution of the uplift pressure including uniform type were considered in case of evaluating stress intensity factor by surface integral method. The effects of body forces, overtopping pressures are also considered and a parametric study of gravity dams under the assumption of LEFM is performed.

• Journal of the Korean Geosynthetics Society
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• v.14 no.2
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• pp.11-21
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• 2015

According to the damage investigation in 2002, the failures of river levee were caused by overflow, erosion, and unstable body conditions due to piping, inappropriate embanking materials, and poor compaction. Especially, overflow was identified as a main reason that induces levee failure by 39.5% from the distribution of failure types. The major parameters, such as levee collapsing angle (${\theta}$), levee collapsing rate (k) affect inundation velocity and area size during the analysis of inundation modeling, however, domestic research effort on this area is still insufficient. In this paper authors conducted levee failure experiments of 4 levee height types, 0.20 m, 0.25 m, 0.30 m, and 0.40 m based on theassumption of Froude Similarity (${\lambda}_{Fr}=1$). As a result, the authors suggested a levee failure mechanism according to the levee heights (H), a collapse extension lengthwhich is around, levee collapse angle (${\theta}$), levee collapse rate (k).

• Journal of Korean Society of Steel Construction
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• v.12 no.6
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• pp.701-713
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• 2000

In this study, the 4-point bending test been performed in order to estimate effect of grinding on fatigue characteristics quantitatively for as-welded specimen, grinding specimen & TIG-dressing specimen for non load-carrying fillet welded joints subjected to pure bending. As a result of fatigue tests, fatigue strength at $2{\times}106$cycles of grinding specimen and TIG-dressing specimen has been increased compared with as-welded specimen and satisfied the grade of fatigue strength prescribed in specifications of domestics and AASHTO & JSSC. As a result of beachmark test, fatigue cracks on all specimens have occurred at several points where stress

• Journal of the Computational Structural Engineering Institute of Korea
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• v.33 no.1
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• pp.17-23
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• 2020

In this study, the behaviors of a vessel and the ground during the vessel impacting an underwater slope that is part of an artificial protective island are analyzed using the coupled Eulerian-Lagrangian scheme. To consider the large deformation including the shear failure of soil, the Eulerian domain is used to model the ground and water, while the impacting objects are modeled as the Lagrangian domain. For efficiency, the mass scaling scheme is applied to the modeling of the impacting objects, and the ground is modeled by setting the Eulerian volume fraction values. To verify the applicability of the constructed model, a dynamic penetration anchor problem is analyzed. The impacting vessel is modeled using solid elements following the external shape of a container ship, and an analysis of a collision on the slope is performed. As a result, collision behaviors such as displacement, velocity, and dissipation energy are estimated, and the necessity of a parametric study as further research is established.