• Parasites, Hosts and Diseases
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• v.21 no.2
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• pp.241-245
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• 1983

PraziquantEI ($Distocide^{\circledR}$), the KcrEan product, was tEstEd for its safety and Efficacy in treatmEnt of Clonorchis sinensiJ infccticn during the period from April to SeptembEr, 1983 in Korea. A total of 55 egg positive cases were selected and treated with the regimen of 25 mg/kg t.i.d. for 1 day (total 75 mg/kg). The follow-up stool examination was done in 47 cases by cellophane thir;k smear and Stoll's egg counting techniques. The 8 uncured cases were treated again with the same regimen. The laboratory tests for blood picture and liver function were done in 27 cases and compared before and after the treatment. The results obtainEd are as follows: 1. After single course treatment, the cure and egg reduction rates were 83.0 and 99.1% respectively. With the second treatment, excellent results of 100% in both rates were obtained. 2. Several kinds of side effects such as dizziness, headache, etc. were complained by 29 cases (61.7 %), however, those were so mild and transient that no special treatment was necessary. 3. No significant change in laboratory findings was recognizable before and after the treatment. From the above results, it is concluded that $Distocide^{\circledR}$ is as effective and safe as $Biltricide^{\circledR}$ and highly recommendable in treatment of C. sinensis infection.

• The Journal of the Korea Contents Association
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• v.20 no.10
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• pp.424-435
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• 2020

The study was descriptive survey research for establishment of patient safety culture in small and medium-sized hospitals as providing baseline data of educational program regarding safe medication and prevention of near miss on medication, checking influencing factors of nurses near miss experience on medication in small and medium-sized hospital. The collected data was analyzed by SPSS/WIN 20.0 program to obtain mean, frequency, x²-test, independent t-test, one-way ANOVA, logistic regression. The influencing factors of near miss experience on medication was working department and patient safety culture among general characteristic. The nurses who were working in general ward had lesser chance to experience near miss rather than nurses working in special department (Odds ratio:2.23, 95%, Confidence Interval: 1.07~4.67, p=.032). The 1 point higher in patient safety culture, the lesser chance to experience in near miss (Odds ratio: 2.24, 95% Confidence Interval: 1.02~4.95, p=.045). To sum up the result of this study, nurses working in special department had higher chance to experience near miss rather than nurses working in general wards. The higher patient safety culture awareness was the lower near miss was experienced. Thus, miss surveillance system for improvement of nurses' patient safety culture awareness should be developed. Moreover, educational program for medication considering nurses' career and department' character should be requested with simulation training considering and theory education.

• Korean journal of applied entomology
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• v.20 no.2 s.47
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• pp.103-106
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• 1981

This experiment was carried out to investigate the vertical penetration and diffusion of fumigants for soybean disinfection in jumbo silo. The results were as follows, 1. Using the methylbromide independently as a soybean fumigant, penetration and diffusing velocity of methylbromide gas which moved from the top to the bottom through the vertica1 silo was too rapidly, it was possible to find out more 60mg/l of methylbromide gas concentration at bottom of silo within 4 hours after beginning the fumigation. And it showed the tendency of reducing methylbromide gas concentration gradually over the 10 hours from tile beginning the fumigation. 2. In case of added $CO_2$ gas to the methylbromide as a carrier is much more rapid velocity of penetration and diffusion of methylbromide gas than that of methylbromide gas independently. Therefore methylbromide gas concentration at bottom of silo was detected over the 70mg/l within 1.5 hours after beginning the fumigation.. 3. On the other hand, hence the phostoxin as a soybean fumigant was less velocity of Penetration and diffusion of the gas through the vertical silo compare to methylbromide gas, the phostoxin gas concentration couldn't detect over the 10mg/1 during the whole fumigation period at the bottomside of silo. 4. Test insects (rice weevil; sitophilus oryzae. L.) inserted at bottom of silo for examine the fumigation effect were killed completly by using the methylbromide independently and added $CO_2$ gas to methylbromide, while using the phostoxin the test insects were most alive.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.2
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• pp.979-988
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• 2014

Purpose: The purpose of this study was to examine the relationship between nurse's perception of organizational characteristics including safety climate and work environment and barrier to medication error reporting. Methods: We surveyed 334 nurses from 7 hospitals. An assessment survey was consisted of modified safety climate scale, practice environment scale and barrier to medication error reporting. The data were collected from September 2012. Descriptive statistics, Pearson correlation coefficient, canonical correlation were used. Results: Organizational characteristics were related to barrier to medication error reporting with three significant canonical variables. The first canonical correlation coefficient was .50(Wilks' ${\lambda}$=0.61, df=32, p<.001), that of the second was .35(Wilks' ${\lambda}$=0.81, df=21, p<.001) and that of the third was .22(Wilks' ${\lambda}$=0.93, df=12, p=.018). The first variate indicated higher perception of safety climate variables and work environment variables were related lower barrier to medication error reporting variables except fear for error reporting. The second variate showed higher perception of 'safety climate between healthcare provider' and higher 'nurse participation in hospital affairs' and 'staffing and resource adequacy' were related to lower 'fear' and 'administrative response' in barrier to medication error reporting variables. Conclusion: Strategies for barrier to medication error reporting and improvement of organizational characteristics including safety climate and work environment should be implemented.

• Tuberculosis and Respiratory Diseases
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• v.47 no.6
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• pp.775-785
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• 1999

Background : Though surgery plays an important role in the management of patients with Mycobacterium tuberculosis infection, there is little information regarding the timing of resection. We tried to find out the ideal timing of operation. Method: A retrospective review was performed in 69 patients underwent pulmonary resection for pulmonary tuberculosis between January 1993 and December 1997. They were categorized into various groups according to the length of preoperative specific drug therapy. The rates of treatment failure, realpse and complication in each group were compared statistically by $x^2$-test. Results: Eighty one point two percent were men and 18.8 % women with a median age of 33 years(range, 16 to 63 years). The mean number of resistant drugs was 3.l(range, 0 to 9). Patients were treated preoperatively with multidrug regimens, which mean number of preoperative specific drugs was 4.6, in an effort to reduce the mycobacterial burden with the mean length of preoperative drug therapy, 5.0 months. Postoperative treatment was conducted for a mean period of 13.0 months with a mean number of postoperative specific drugs, 4.4. Postoperative treatment failures were confirmed in 8 among 69 patients(11.6%). 2 of these 8 patients were showed up in the preoperative 3 to 4 months medication group and each of the rest was occurred in the preoperative 2 to 3, 5 to 6, 6 to 7, 12 to 13, 17 to 18 months, less than one month medication group, respectively. 59 of 69 patients were available for evaluation of the relapse rate with the mean duration of the postoperative follow-up, 19.8 months. In 4 patients bacterial relapse was confirmed(6.8%). Each of these 4 was in the preoperative 1 to 2, 2 to 3, 3 to 4, 5 to 6 months medication group. Categorized into various groups according to the length of preoperative specific therapy, there were no statistical significances of the treatment failure rate, relapse rate and complication rate in the groups. There were seven treatment failures of 28 who were AFB culture positive until the time of operation(25%, p<0.01). Categorized the preoperative AFB culture positive group into various groups according to the length of preoperative drug therapy, there were no statistical significances, either. Conclusion: We believe that operation plays an important ancillary role in the treatment of pulmonary tuberculosis. Our results indicate that the timing of resection according to the length of preoperative drug therapy may not cause trouble.

• 건강소식
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• v.3 no.6 s.21
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• pp.12-15
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• 1975

• 건강소식
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• v.6 no.8 s.46
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• pp.34-35
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• 1982

• Korean Journal of Clinical Pharmacy
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• v.2 no.1
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• pp.75-77
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• 1992

• Monthly Korean Chicken
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• v.18 no.1
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• pp.100-107
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• 2012

• The Korea Swine Journal
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• v.14 no.9 s.157
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• pp.107-110
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• 1992