• Journal of Information Management
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• v.32 no.2
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• pp.26-39
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• 2001

Various controlled vocabularies such as thesaurus and classification used for effective information retrieval contain different terms in expressing the same concept or meaning. National Library of Medicine has developed the Unified Medical Language System(UMLS) to solve the problems of information retrieval and integration resulted from the difference of concepts between different sources. The UMLS development was initiated in 1982 as a long-term project, and the 2001 edition of the UMLS consists of three parts : Metathesaurus, Semantic Network, and SPECIALIST Lexicon. This paper reviews background and structure of the UMLS including applications in PubMed, NLM Gateway.

• Proceedings of the IEEK Conference
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• 2003.11b
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• pp.129-132
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• 2003

The metathesaurus(UMLS, 2003AA edition) supports multi language and includes 875, 233 concepts, 2, 146, 897 concept names. It is impossible for PubMed or NLM serve searching of the metatheaurus to retrieval using a query that is not to be text, a fault sentence structure or a part of concept name. That means the user notice correctly suitable medical words in order to get correct answer, otherwise she or he can't find information that they want to find I propose that the method of searching unified medical language system using automatic modified a query for problem that I mentioned. This method use dictionary that is standard for automation of modified query gauge similarity between query and dictionary using string comparison algorithm. And then, the tested term converse the form of metathesaurus for optimized result. For the evaluation of method, I select some query and I contrast NLM method that renewed Aug. 2003.

• Proceedings of the Korean Information Science Society Conference
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• 2003.10a
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• pp.82-84
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• 2003

UMLS 의미망은 크기가 방대하고 복잡하여 사용자가 이해하기가 어렵고 화면상에 모든 의미망을 모두 표현할 수 없다는 단점을 가지고 있다. 이 문제를 해결하기 위해 의미망을 효율적으로 분할하기 위한 규칙들이 소개되고 있지만 이것은 UMLS 의미망이 수정될 때마다 규칙을 적용하여 수작업으로 분류를 해야한다는 단점이 있다. 이 문제점을 해결하기 위해 유전자 알고리즘을 이용한 UMLS 의미망의 자동 군집화 방법을 제안한다. 제안한 방법은 각각의 의미유형 간의 연결된 의미관계를 사용하여 의미망을 구조적으로 유사한 의미유형 집합들로 군집화하고 규칙에 의한 군집 방법의 결과 비교 평가한다.

• Proceedings of the Korea Society for Industrial Systems Conference
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• 2002.06a
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• pp.148-155
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• 2002

Multithreaded models improve the efficiency of parallel systems by combining inner parallelism, asynchronous data availability and the locality of von Neumann model. This model executes thread code which is generated by compiler and of which quality is given by the method of generation. But multithreaded models have the demerit that execution model is restricted to a specific platform. On the contrary, Java has the platform independency, so if we can translate from threads code to Java bytecode, we can use the advantages of multithreaded models in many platforms. Java executes Java bytecode which is intermediate language format for Java virtual machine. Java bytecode plays a role of an intermediate language in translator and Java virtual machine work as back-end in translator. But, Java bytecode which is translated from multithreaded models have the demerit that it is not secure. This paper, multhithread code whose feature of platform independent can execute in java virtual machine. We design and implement translator which translate from thread code of multithreaded code to Java bytecode and which check secure problems from Java bytecode.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2022.05a
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• pp.270-272
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• 2022

Safety is one of the factors that prevent clinical drugs from being distributed on the market. In the case of neurotoxicity, which is the main cause of safety problems caused by drug side effects, risk assessment of drugs and compounds is required in advance. Currently, experiments for testing drug safety are based on animal experimetns, which have the disadvantage of being time-consuming and expensive. Therefore in order to solve the above problem, a neurotoxic prediction model through an in silico experiment was suggested. In this study, the category of neurotoxicity was expanded using a unified medical language system and various related compound data were obtained based on an integrated database. The SMILES (Simplified Molecular Input Line Entry System) of the obtained compounds were converted into fingerprints and it is used as input of machine learning. The model finally predicts the presence or absence of neurotoxicity. The experiment proposed in this study can reduce the time and cost required for the in vivo experiment. Furthermore, it is expected to shorten the research period for new drug development and reduce the burden of suspension of development.