• Journal of the Korean Orthopaedic Association
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• v.54 no.5
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• pp.463-468
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• 2019

Congenital insensitivity to pain with anhidrosis (CIPA) is a rare disease that affects the sensory and autonomic nervous system. The patients do not have the ability to sense different sensations, such as pain, which tends to lead to different injuries. In addition, the patients suffer from fluctuations in body temperature due to autonomic involvement. The present case was a five-year-old girl with a neglected distal femur fracture. X-rays taken during the follow-up showed marked callus formation and pseudarthrosis of the distal femur. She had biting injuries of the tongue, auto-amputation of the fingers, some developmental delay and a history of recurrent fever with an unknown origin. The electrodiagnostic study was normal. The quantitative sudomotor axon reflex test revealed markedly reduced postganglionic sudomotor axonal responses at all sites recorded on the left. She was diagnosed with CIPA. As the initial presentation of CIPA involves the musculoskeletal system, orthopedic surgeons should have a high index of suspicion.

• Korean Journal of Psychosomatic Medicine
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• v.10 no.2
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• pp.101-109
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• 2002

Objectives: Cognitive-behavioral scientists have long been interested in how a pain patient's cognition such as locus of control relates to coping and adjustment. The present study examined the relationship of locus of control orientation to pain coping strategies, psychological distress and perceived pain intensity of patients with pain. Methods : Subjects were 96 patients with pain who visited pain clinic. All patients were administered the Multidimensional Health Locus of Control Scales, the Minnesota Multiphasic Personality Inventory, the Coping Strategies Questionnaire, and rating for perceived pain intensity, distress, and duration. Results : Correlational analysis revealed that patients who viewed outcomes as controlled by internality tended to have better ability to control and decrease pain. Also they tended to be less depressed and anxious. Regression analysis indicated that patients having a internal locus of control were more likely to use coping self-statement and reinterpreting pain sensation. Powerful others and chance locus of control orientation were predicted reliance on catastrophizing. Conclusion : The clinical implication of the present study is that cognitive factors of patients with pain such as locus of control influence emotional distress and coping. this study show that these factors should be applied to cognitive behavioral therapeutic intervention.

• The Korean Journal of Pain
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• v.3 no.2
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• pp.144-148
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• 1990

정상인에서 Guanethidine Nicardipine Nitroglycerine Prostaglandin $E_1$을 피하주사하고 지속적인 복사열을 주사한 후에 Pain Meter NYT-5를 이용하여 동통역치를 측정하였다. 통증역치는 Guanethidine과 Nicardipine에 의해 상승되었으며 Nitroglycerine에 의해서는 거의 변화가 없고 Prostaglandin $E_1$에 의해서는 감소되었다. 이러한 변화는 지각신경섬유의 말단 감각수용체에 대한 감수성이 이들 혈관확장제에 대하여 서로 다른 작용을 나타내는것 같다.

• The Korean Journal of Pain
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• v.7 no.1
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• pp.116-118
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• 1994

Neurolytic splanchnic nerve block is effective for treatment of intractable upper abdominal cancer in. The possibility of neurologic complication cannot be completely precluded. A 53 year-old female patient with hepatoma and lung metastasis was submitted for splanchnic nerve block with alcohol. Splanchnic nerve block was performed under radiologic control by image intensifier without any difficulty during procedure. One day after the block, she complained of numbness with sensory deficit in bilateral inguinal area. Neurologic examination revealed that asymmetrical anesthesia, hypoesthesia at $T_{12}-L_2$. She was discharged 70 days after the block with partial improvement. The possibility of alcohol spreading to the low theracic and upper lumbar somatic nerves cannot be excluded.

• Proceedings of the Korean Institute of Industrial Safety Conference
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• 2002.05a
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• pp.307-312
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• 2002

새로운 산업 구조와 변화된 사회 환경으로 인해 우리나라에서 최근 급증하고 있는 직업병 중의 하나가 직업 성 근골격계질환(Work-related Musculoskeletal Disorders, WMSDs)이다. 이 질환은 특정한 신체 부위의 반복 작업과 불편하고 부자연스러운 작업 자세, 강한 노동 강도, 과도한 힘, 불충분한 휴식, 추운 작업 환경, 진통 등이 원인이 되어 목, 어깨, 팔꿈치, 손목, 손가락, 허리, 다리 등 주로 관절 부위를 중심으로 근육과 혈관, 신경 등에 미세한 손상이 생겨 결국 통증과 감각 이상을 호소하는 근골격계질환의 만성적인 건강장해다.(중략)

• Journal of Dental Rehabilitation and Applied Science
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• v.28 no.2
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• pp.171-178
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• 2012

Botulinum toxin type A (BoNT-A) has been applied successfully to treat chronic migraine, dystonia, spasticity and temporomandubular disorders(TMDs) as well as frontal wrinkle and glabella wrinkle. Recently it has been reported that BoNT-A, reversibly blocks presynaptic acetylcholine release, also inhibits the release of substance P, CGRP(calcitonin gene related peptide) and glutamate related to peripheral sensitization and neurogenic inflammation in sensory nerve, In this study we reviewed animal nerve injury model such as rat and rabbit and identify the analgesic effect and mechanism of nerve injury pain after dental treatment.

• Journal of dental hygiene science
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• v.9 no.1
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• pp.91-98
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• 2009

The aging of Korean society is coming to the fore and its speed is unprecedented. Along with the volume rise in the population of the elderly, the rise of the elderly of means and high education stimulates the transition of our focus from "a desire of longevity" to "successful aging". The research objective is to classify groups by the different definitions of disability thinking of the geriatric oral health care. We targeted 34 aged people who live in Pusan Metropolis and analyzed the collected data and classified them into two types. The first type is the 'blunting of taste & oral pain' which is identified as a group. The second type is the 'blunting of taste & lowering quality of life' which is identified as a group. The common positive statements are 'There are some experiences to feel pain on and below tongue, cheek and upper palatine.', 'There are some experiences to feel unsatisfactory life'.

• Journal of the Korea Society of Computer and Information
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• v.28 no.5
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• pp.95-102
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• 2023

The purpose of this study was to the effects of the Sling Neurac stabilization exercise(SNSE) on pain, cervical lordosis angle(CLA), and cervical gravity line(CGL) in young adults with a forward head posture. The subjects of the study were selected as SNSEG(n=10) and control group(n=10), they were conducted for 70 minutes three times a week for 8 weeks. Study results showed that pain(p<.001), CGLe(p<.01) were significantly decreased and CLA(p<.001) were also significantly increased in the SNSEG. In conclusion, SNSE is effective in improving the proprioceptive sense of the LM group and activating the muscle. Co-activation with the GM group was found to be effective in improving the CLA and CGL. Therefore, reactivation of the deep neck flexors and suboccipital muscles is an important factor in pain control and postural alignment, and is suggested as an effective intervention method to improve forward head posture.

• Journal of The Korean Dental Society of Anesthesiology
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• v.8 no.1
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• pp.29-34
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• 2008

배경: 신경병증성 통증은 스테로이드, 아편유사제 등의 진통제에 잘 반응하지 않는다. 하지만 염증성 매개물질들이 신경병증성 통증의 발생에 관여한다는 보고가 있다. 특히 선택적 COX2 억제제인 celecoxib의 신경병증성 통증에 대한 효과에 관해서 상반된 연구결과가 존재한다. 본 연구는 신경병증성 통증 모델인 척추신경 결찰모델을 이용 기계적, 냉각 이질통 및 온도감각 과민현상의 발현에 celecoxib이 미치는 영향을 관찰하여 celecoxib의 항통각효과를 확인하고자 하였다. 방법: 30마리의 쥐를 이용 척추신경을 결찰하여 신경병증성 통증을 유도하였다 celecoxib (1, 10, 100, and 300 mg/kg)을 경구 투여하였고 총 30마리 중 12마리의 쥐에서 열, 기계적자극에 대해서 통각과민, 냉각자극에 의해 이질통이 발생하였다. 약물 투여 후 30, 60, 120, 180분 후 von Frey, 냉각자극검사, Hargreaves검사를 시행하여 쥐의 행동변화를 관찰하였다. 결과: 신경결찰 후 5일 후에 celecoxib의 용량에 관계없이 열, 기계적 자극에 의한 통각과민, 냉각 자극에 대한 이질통을 감소시키지 않았다(P > 0.05). 또한 celecoxib투여에 의한 장기간의 항 통각효과는 관찰되지 않았다(P > 0.05). 결론: celecoxib을 경구로 투여하였을 때 장기간 유지된 신경병증성 통증 흰쥐에서 약의 투여용량, 투여기간에 따른 항 통각작용은 관찰되지 않았다. 따라서 조직 손상후 발생된 장기간의 신경병증성 통증에 있어서 celecoxib은 효과가 없는 것으로 사료된다.

• Journal of Chest Surgery
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• v.43 no.1
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• pp.53-57
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• 2010

Background: The purpose of this study is to evaluate intercostal neuropathy after rib fracture and to determine the severity of intercostal neuropathy with using a numerical rating scale and according to the duration of pain and the body mass index. Material and Method: We measured the positive sharp wave and fibrillation on the intercostal and paraspinal muscles in the thoracic region by performing needle electromyography in 47 patients who had intercostal neuralgia after rib fracture and who had needed daily analgesic for more than three months. Result: We diagnosed 11 cases as intercostal neuropathy among the 47 cases. Of the total 11 cases, 8 were male and 3 were female and they were most often of an active generation in the community. The common location of intercostal neuropathy was the intercostal space below the rib fracture and from the 7th to the 12th intercostal rib area. The incidence of intercostal neuropathy was significantly related with multiple rib fracture rather than single rib fracture. The symptoms observed were chest pain (90.9%), sensory change (81.8%), paresthesia and numbness (63.6%), back pain (27.2%) and muscle atrophy (18.2%). The numerical rating scale, the duration of pain and the body mass index showed no significant correlation with the severity of intercostal neuropathy. Conclusion: We concluded that the electrodiagnostic approach with considering the affecting factors and the clinical findings will be helpful for diagnosing and treating persistent intercostal neuralgic pain (more than 3 months) after rib fracture.