• Title/Summary/Keyword: 통계적파라미터 뇌지도작성

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A Study on the Deviation of Cluster Based on Template Images of Korean Children's Brain SPECT Image Using the Statistical Parametic Mapping (통계적 파라미터 뇌지도작성을 이용한 국내 어린이 뇌 SPECT영상의 표준틀영상에 따른 화소덩어리의 편차연구)

  • 신동호;박성옥;권수일;조철우;윤석남;이명훈;신동오
    • Progress in Medical Physics
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    • v.15 no.1
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    • pp.45-53
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    • 2004
  • SPM has been widely applied for comparison studios of the functional image data among groups of patients or individuals under different conditions and these images are from people ranging from children to adults. However, the analysis of children's brain images by using SPM can make children's brain images normalized to an adult's template image and this can result in some errors. So this study created the children's mean MR images based on the Magnetic Resonance Images of 36 normal children (age: 2~6, average age: 4.36, SD age: 1.41, M/F: 17/19), and the children's mean SPECT images by using SPECT images of 13 normal children (age: 2~6, average age: 4.80, SD age: 1.17, M/F: 10/3). We created the Korean children's brain template image, based on those mean images, and then we compared between the positions of the clusters, based on the blood flow, by normalizing ADHD children's SPECT image to Korean children's template image and SPM adult's template image. As a result of the analysis, the variation of the cluster positions was found to be a maximum of 25 ㎜. Therefore, we should be aware that we need to consider the template image and the p-value when we analyze the chlidren's brain image by using SPM.

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