• 동물약계
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• no.79
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• pp.3-4
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• 2001

[ $\cdot$ ]국립수의과학검역원 보유 산업재산권 이용 $\cdot$농림부, '전국 일제소독의 날' 홍보 요청 $\cdot$가축방역사업용 예방약품 품목 및 단가 조사 $\cdot$동물약사감시 행정처분 결과 홍보 $\cdot$협회 제4차 이사회 개최 $\cdot$사료첨가용 동물약품 허가요건 완화 건의 $\cdot$동물약사 관련 회원사 직원교육 실시 $\cdot$돼지콜레라 청정화 추진 공청회 참석 $\cdot$한국 구제역 청정국 지위 조기 회복 $\cdot$제2회 KAHPA컵 골프대회 개최 $\cdot$염산 옥시테트라싸이클린 공급 오퍼상 선정

• Korean Journal of Microbiology
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• v.23 no.2
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• pp.107-114
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• 1985

In order to use for recipient strains of RP4:Mu cts, 5 strainsof Rhizobium were selected among 32 strains, which were isolated and identified in this study. Hybrid plasmin RP4::Mu cts, which, is temperature sensitive and confers resistance to ampicillin, kanamycin and tetracycline was transfered by conjugation from E. coli to other atrains of C. coli and the symbiotic nitrogen fixer, Rhizobium leguminosarum. Transfer frequencies of RP4::Mu cts plasmid from E. coli to Rhizobium were about $10^{-8}-10^{-7}$ in LB agar and YMA media. The transconjugants were confirmed by demonstrating that the drug-resistant and temperature-sensitive clones isolated were drug-resistant and temperature-sensitive clones isolated were capable of releasing phage and forming plaques. The plaque-forming units of transconjugants were about $10^2\;to\;10^3$. Stability test of RP4::Mucts in Rhizobium represented that most of the transconjugants had drug resistance and produce phage Mu cts.

• Journal of dental hygiene science
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• v.11 no.4
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• pp.299-303
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• 2011

The purpose of this case report was to present an example of an esthetic and functional rehabilitation of anterior teeth with tetracycline discoloration and minor morphological abnormality of a 39-year old female. A chairside computer-aided design/computer-aided manufacturing (CAD/CAM) system with CEREC AC was applied for the prosthetic procedure and all ceramic crowns made with lithum disilicate (IPS e.max CAD) restored the esthetic and functional features of sixteen anterior teeth successfully.

• Journal of Korean Society on Water Environment
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• v.22 no.3
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• pp.527-533
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• 2006

Tetracycline is one of the mostly used antibiotics around the world. The purpose of this study was to evaluate the fate of two different types of tetracycline resistant bacteria in biological wastewater treatment plants. Tetracycline resistant enterics and heterotrophic bacteria were monitored under two different lab-scale experimental conditions. Tetracycline resistant enteric bacteria showed the lower percentages of total enteric bacteria and net specific growth rate in the monitored activated sludge system as compared to tetracycline resistant heterotrophic bacteria. Therefore, total enterics, potentially E.coli, might not be the best indicator microorganism for evaluating the antibiotic resistant bacteria in biological wastewater treatment plant.

• Journal of Periodontal and Implant Science
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• v.27 no.1
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• pp.79-90
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• 1997

The purpose of this study was to evaluate the substantivity of experimentally developed gel type tetracycline HCl and a mixture of tetracycline-citric acid gel, and compare to those of solution type tetracycline HCl. 11 extracted anterior teeth were subjected to this study. After scaling and root planing teeth were randomly divided into 3 treatments groups : group 1; 3 teeth were irrigated with tetracycline HCl(50mg/ml) solution , group 2; tetracycline gel (5%) was inserted in the periodontal pockets of 3 teeth, group 3; a mixture of tetracycline and citric acid gel was inserted in the pockets of 3 teeth. And 2 teeth treated in 0.9 % sterile saline served as controls. After 5-minute exposure, each tooth immediately extracted and incubated at room temperature for 22 days in tris-buffered saline as a desorption media. The total volume of TBS was removed and replaced with fresh TBS, at 24-h intervals. Removed desorption media transferred to a sterile vial and stored at -70 oC. This procedure was repeated every 24 h throughout the 22-day desorption period. Using Porphyromonas gingivalis as an indicator organism, a microtiter assay was used to evaluate antimicrobial activity desorbed from the teeth. 1. 50mg/ml tetracycline HCl solution exhibited the longest antimicrobial activity. Compared to saline treated group, it showed significant difference on the day 1 and day 2 desorption period. 2. The ODs of 5% tetracycline gel and a mixture of tetracycline-citric acid gel were significantly different during the first 24 hour only. 3. There was no statistically significant difference after the day 3 between the groups.(p<0.05). Despite our expectation a mixture of tetracycline-citric acid gel did not show longer antimicrobial activities than those of tetracycline gel, and the solution type exhibited the longest activities. Because the gel type agents may stay in the subgingival environment longer than the solution, if the teeth were not extracted immediately after the delivery of the agent, the result could be different. hus this result suggests the possibilities of practical use of these kind of gel type agents.

• 동물약계
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• no.75
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• pp.3-4
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• 2001

[ $\cdot$ ]구제역 특별방역대책기간중 집회 개최 금지 $\cdot$구제역 방역훈련(CPX) 실시 $\cdot$항생물질제제 생산$\cdot$수입실적 통보 안내 $\cdot$무허가 어류용 마취제 불법유통 신고 $\cdot$구제역 소독약품 약사감시 강화 안내 $\cdot$동물약사감시 행정처분 결과 홍보 $\cdot$협회 유통전문위원회 1/4분기 정례회의 개최 $\cdot$병역특례업종 지정을 위한 자료 제출 $\cdot$동물용의약품 가격 조사 $\cdot$동물약품 품질관리 협의회 개최 $\cdot$농협중앙회 소독제 긴급구매 입찰 $\cdot$협회 발간 책자 판매 안내 $\cdot$동물약품 품질관리 연수교육 실시 $\cdot$염산 옥시테트라싸이클린 공급가격 인하

• 동물약계
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• no.68
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• pp.4-5
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• 2000

[ $\cdot$ ]동물용의약품등 제조업체 현황 $\cdot$동물용의약품등 수입자 현황 $\cdot$국내생산 동물용의약품 년도별 판매실적 $\cdot$국내생산 동물용의약품 년도별 수출실적 $\cdot$수입완제 동물용의약품 년도별 판매실적 $\cdot$동물용의약품 년도별 내수 시장규모 $\cdot$동물용의약품 약효별 허가(신고) 현황 $\cdot$제1차 이사회 개최 $\cdot$제8차 정기총회 개최 $\cdot$염산 옥시테트라싸이클린 알선 오퍼상 선정 $\cdot$롱프랑 '아벤티스(Aventis)'로 상호 변경 $\cdot$2000년도 중국 축산 박람회(VIV China 2000) $\cdot$동물약사 법규 개정을 위한 의견 수렴 $\cdot$동물약품 제조용 유당 양허관세 적용 배정 $\cdot$회원 수첩 제작 배부 $\cdot$2000년도 수의사 국가고시 합격자 연구교육시 동물약품업계 홍보

• 동물약계
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• no.80
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• pp.3-4
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• 2001

[ $\cdot$ ]가축전염병 예방약 조달계약 관련 자료 제출 $\cdot$동물약품관리 교육훈련 수요조사 $\cdot$가축전염병 예방약 조달계약 관련 협의회 참석 $\cdot$가축질병$\cdot$축산물위생 등 연구과제 제안 $\cdot$동물약사감시 행정처분 결과 홍보 $\cdot$협회 제5차 이사회 개최 $\cdot$2002년도 양허관세적용 유당 배정희망량 제출 $\cdot$병역대체복무를 위한 지정업체 선정 결과 $\cdot$협회 직원 인사 $\cdot$'동물약품 안전사용 방안' 심포지엄 개최 $\cdot$2002년도 상반기 알찬 거래선 선정 $\cdot$염산옥시테트라싸이클린 및 유당 공급 오퍼상 $\cdot$'한국대체수의학연구회'(가칭) 창립 준비

• 동물약계
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• no.83
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• pp.3-4
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• 2002

[ $\cdot$ ]동물약사감시 행정처분 결과 홍보 $\cdot$구제역 방역훈련(CPX) 실시 $\cdot$제조물책임법 관련 품목허가 정비 안내 $\cdot$돼지콜레라 소독약품 재고현황 보고 $\cdot$돼지콜레라 관련 긴급 협의회 개최 $\cdot$돼지콜레라 방역용 소독약품 기증 $\cdot$돼지콜레라 방역규정 위반사항 처리 $\cdot$동물약품제조용 양허관세적용 유당 추가 배정 $\cdot$중국산 동물용의약품 수입시 유의사항 $\cdot$수입 동물용의약품 GMP 증명서 제출 $\cdot$협회 제4차 이사회 개최 $\cdot$국가전문행정연수원 동물약품 교육 실시 $\cdot$염산옥시테트라싸이클린 공급 오퍼상 선정

• Korean Journal of Veterinary Service
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• v.20 no.4
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• pp.339-348
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• 1997

The purpose of the survey were determined the residual antibiotics and tetracyclines in beef(n=1,364), pork(n=2,817) and chickens(n=1,921) by the EEC 4-plate method, Charm IIand HPLC. The results were summarized as follows ; 1. The recovery rates in spiked samples were 98.8-107.2% for oxytetracycline(OTC), 33.2-48.6% for tetracycline(TC) and 64.1-72.3% for chlortetracycline(CTC) at 0.05-0.1ppm by HPLC using MSPD. 2. Residues of antibiotic were detected from 10 beef(0.75%) and 36 pork(1.31%) by EEC 4-plate method. In case of chickens were not detected. 3. Twenty-eight from 46 positive samples by the EEC 4-plate method were classified as TCs(60.9 %) by Charm II and TC of 12 samples were detected by HPLC. 4. Ten samples were detected levels of OTC ranging from 0.035 to 0.635 ppm and 3 samples were levels of CTC ranging from 0.066 to 0.150 ppm. OTC and CTC levels in 3 beef and 4 pork samples were exceeded the current tolerance level of 0.1 ppm.