• Proceedings of the Korean Society of Computer Information Conference
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• 2022.01a
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• pp.97-98
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• 2022

코로나바이러스-19 팬데믹 이후 매일 수만 명의 환자가 발생하고 있다. 보건당국은 사람들의 생활 안전을 보호하기 위해 공항, 정류장 등 공공장소에서는 반드시 마스크를 착용하라고 지시하고 있다. 마스크를 착용하는 목적은 감염으로부터 신체를 보호하고 바이러스 전파와 확산을 막기 위한 것이다. 공공장소에서는 많은 인원에 대한 일괄적인 마스크 착용 검사를 하기 어렵고, 육안으로 확인하는 마스크 착용 검사 방법은 인파가 몰리는 장소에서 검사 효율이 떨어지며 누락되는 경우도 많이 발생한다. 본 연구에서는 입력 이미지에 존재하는 얼굴 영역을 YOLOv4와 YOLOv5 모델을 통해 예측하여 마스크의 착용 여부를 판단하되, 앙상블 기법을 적용하여 보다 효과적인 BB(Bounding Box) 추출 및 마스크 착용 탐지 기법을 적용한다. 따라서 공공장소의 마스크 착용실태를 효과적으로 모니터링 할 수 있는 방법을 제안한다.

• Journal of the korean academy of Pediatric Dentistry
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• v.48 no.3
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• pp.269-279
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• 2021

The purpose of this study is to evaluate the effect of the spread of a new type of coronavirus infection (COVID-19) on the mental state in school-age children and parents focusing on the aspects of sleep disorders and depression. A questionnaire survey was conducted for 123 parents and 108 school-age children who visited Department of Pediatric Dentistry, Kyung Hee University Dental Hospital at Gangdong from April 2, 2020 through April 25, 2020, via the direct writing method. Participants were assessed with Pittsburgh Sleep Quality Index, Generalized Anxiety Disorder (GAD)-7, Center for Epidemiology Scale for Depression. Logistic regressions were used with a level of significance of 5%. The prevalence of GAD, depression, and poor sleep in parents were 34.1%, 17.1% and 44.7%, respectively. The prevalence of GAD in children was 20.4%. Logistic regression showed that stress from Emergency Alert Messages about COVID-19 was associated with GAD and depression in parents. In children, the degree of emotional change after COVID-19 was associated with GAD. This study confirmed that there was a change in the psychological status of children and guardians due to the epidemic of coronavirus disease-2019, and it would be necessary to consider their psychological status during dental treatment.

• Journal of the korean academy of Pediatric Dentistry
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• v.49 no.1
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• pp.76-84
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• 2022

The study was conducted to analyze the impacts of COVID-19 on the number of dental trauma patients. Based on the data provided by the Health Insurance Review and Assessment Service's Healthcare Bigdata Hub, dental trauma which occurred from 2010 to 2020 was analyzed. Since the outbreak of COVID-19, the incidence of dental trauma per 100,000 decreased compared to the average Incidence between 2017 to 2019. By age, it decreased by 5.4% (p = 0.017) for 0 - 4 years old, 30.3% (p < 0.001) for 5 - 9 years old, 39.5% (p < 0.001) for 10 - 14 years old, 14.5% (p = 0.002) for 15 - 19 years old, 1.3% for 20 - 29 years old, 0.2% for 40 - 49 years old, 2.7% for 50 - 59 years old, 1.2% for 60 years old or older, but it increased by 2.5% for 30 - 39 years old. Compared monthly, before and after the outbreak of COVID-19 confirmed patients, the number of dental trauma patients dropped sharply. After the outbreak of COVID-19, the incidence of dental trauma decreased significantly for under 20 years old, but the decrease was not significant for 20 years old or older.

• Journal of Korean society of Dental Hygiene
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• v.21 no.6
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• pp.695-701
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• 2021

Objectives: This study aimed to determine the effect of COVID-19-induced household economic deterioration on gingival pain and bleeding. Methods: Data from the 16th Adolescent Health Behavior Survey 2020 were used. A total of 57,925 adolescents were included in this cross-sectional study. We evaluated the worsening of the COVID-19-induced household economic situation, gingival pain, and bleeding. All surveys were assessed in a subjective non-face-to-face online interview. Data were analyzed using descriptive statistics, chi-squared tests, and logistic regression. Results: The overall prevalence of gingival pain and bleeding symptoms in the study population was 19.2%. People with COVID-19 were more likely to suffer from gingival pain and gingival bleeding than those who did not have economic deterioration due to COVID-19. There was no economic deterioration due to COVID-19 (aOR=1.048, 95% CI=1.034-1.227) and worsened very much (aOR=1.358, 95% CI=1.164-1.585). Conclusions: There were more cases of gingival pain and gingival bleeding, which are early symptoms of periodontal disease, in patients with COVID-19 compared to cases without deterioration of the household economic situation due to COVID-19. It is necessary to measure and study gingival bleeding objectively rather than relying on self-reports.

• Korean Journal of Psychosomatic Medicine
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• v.30 no.1
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• pp.22-29
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• 2022

Objectives : In this study, we evaluate psychological stress, symptoms of anxiety and depressed mood and resilience which medical residents and interns perceived during COVID-19 event, then investigate the associations between stress and the symptoms and mediating effect of resilience on the associations. Methods : In this study, we made a self-reporting form to evaluate psychological stress with perceived stress scale (PSS), symptoms of anxiety and depressed mood with Hospital anxiety and depression scale (HAD), and resilience with Conner-Davidson Resilience Scale (CD-RISC). Medical residents and interns, who worked in a hospital during COVID-19 event, filled the self-reporting forms from july, 2020 to august, 2020. We conducted a Pearson correlation coefficient and a multiple regression to confirm association between psychological stress and symptoms of anxiety and depressed mood, then mediating effect of resilience. Results : The higher stress perceived, the more symptoms of anxiety and depressed mood were reported by medical residents and interns. The higher resilience is associated with lower stress and less symptoms of anxiety and depressed mood, which resilience is proven to mediate partially the association between stress and symptoms of depressed mood. Conclusions : This study shows that resilience has a partial mediating effects on the association between stress and psychological pathology especially depressed mood, given that medical residents and interns were under psychological distress during COVID-19 event. This suggests that resilience is the key for medical trainees to overcome the future crisis like COVID-19 event.

• The Korean Society of Law and Medicine
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• v.21 no.3
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• pp.37-75
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• 2020

There have been affluent studies on the development of new drugs and these efforts have been crystallized into a separate field of pharmacology. Yet, a normative analysis pertinent to the development of new medicine is still in a dire need, except for studies regarding medical ethics. This piece of work aims to contemplate on the legal issues concerning the development of new drug, encompassing each and every stage of the development. In order to maximize the practicability of the research method adopted as aforementioned, this work strives to analyze the developing process of COVID-19 vaccine. The first step would be to introduce the developmental stages of inventing a new drug, especially that of a COVID-19 vaccine. After then, legal issues related to each developmental stage would be discussed. Henceforth, the legal analysis would contribute to predicting upcoming legal complexities and will be able to offer normative implications for the invention of new medicines.

• Science of Emotion and Sensibility
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• v.24 no.4
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• pp.39-52
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• 2021

This study aims to investigate the effect of the coronavirus disease 2019 (COVID-19) epidemic on negative emotions, such as anxiety, depression, fear, and stress, in Korean college students. The study recruited students from J University and conducted interviews across three time points, namely, March 2019, March 2020, and November 2020. For three time points, the participants responded to structured questions about situations they may have encountered and they were asked to summarize their responses. Repeated-measures ANOVAs were performed to examine whether differences exist in negative emotions between time points. Furthermore, polynomial trend analyses were conducted to examine resultant patterns over time. The results revealed that negative emotions displayed significant differences between time points. Moreover, trend analyses revealed a curvilinear pattern, which indicates that negative emotions increased and were then sustained. These findings suggest that negative emotions may continue to become prevalent among college students with the increased impacts of the ongoing COVID-19 pandemic. The study discussed the need for psychological support systems, such as stress management and psychological counseling, for college students.

• Microbiology and Biotechnology Letters
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• v.39 no.2
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• pp.140-145
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• 2011

Porcine epidemic diarrhea virus (PEDV) infection causes acute enteritis with lethal watery diarrhea resulting in a high mortality rate in piglets. As with the other members of group 1 coronaviruses, PEDV also utilizes the host aminopeptidase N (APN) as the major cellular receptor for entry into target cells. The coronavirus spike (S) protein is known to interact with the cellular surface for viral attachment and the S1 domain of all characterized coronaviruses contains a receptor-binding domain (RBD) that mediates a specific high-affinity interaction with their respective cellular receptors. Although the RBDs of several coronaviruses have been mapped, the location of the PEDV RBD has to date not been defined. As a first step toward the identification of the region of the S protein of the PEDV that is critical for recognition with the cellular receptor, we generated a series of S1-truncated variants and examined their abilities to bind to the porcine APN (pAPN) receptor. Our data indicate that the N-terminus of the S1 domain is required for pAPN association. The results from the present study may assist in our understanding of the molecular interactions between the PEDV S protein and the pAPN receptor.

• Journal of Advanced Technology Convergence
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• v.2 no.3
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• pp.25-32
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• 2023

This study was conducted to find out the relationship between knowledge and attitudes about COVID-19 and infection control performance among college students in paramedicine. The subjects of the study were 154 university students attending a 3-4 year paramedicine located in Gwangju Metropolitan City, Jeollabuk-do Province, and the collected data were frequency, percentage, sum, average and It was analyzed by standard deviation, t-test, ANOVA(Scheffe), Pearson's Correlation Coefficient, and Multiple Linear Regression. The order of attitude and knowledge about COVID-19 affected the infection control performance of college students in the paramedicine. Therefore, it is necessary to develop and apply regular or non-regular curriculum and multidisciplinary curriculum that can improve knowledge and attitudes about COVID-19 in order to improve the infection control performance of paramedic students.

• Clinical and Experimental Pediatrics
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• v.52 no.11
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• pp.1241-1248
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• 2009

Purpose:The etiology of Kawasaki disease (KD) is still unknown. Recently, an association between human coronavirus NL63 (HCoV-NL63) and KD was implicated. Hence, we attempted to determine the association between KD and acute respiratory viral infections. Methods:Nasopharyngeal aspirate samples were obtained from 54 patients diagnosed with KD at the Seoul National University (SNU) Children's Hospital and SNU-Bundang Hospital between October 2003 and September 2006. Viral diagnoses of 11 respiratory viruses were made using multiplex reverse transcriptase-polymerase chain reaction (RT-PCR): respiratory syncytial virus (RSV), adenovirus, rhinovirus (RV), parainfluenza viruses (PIVs) 1 and 3, influenza viruses (IFVs) A and B, human metapneumovirus (HMPV), human bocavirus (HBoV), HCoV OC43/229E, and HCoV-NL63. Clinical data were reviewed retrospectively. Results:The median age was 32 months (6 months-10.4 years). Respiratory symptoms were observed in 37 patients (69%). The following respiratory viruses were identified in 12 patients (22%): RV (n=4), PIV-3 (n=2), HBoV (n=2), and adenovirus, RSV, PIV-1, IFV-A, and HCoV-NL63 (n=1). Co-infection with PIV-3 and RV was observed in one patient. Respiratory symptoms were observed in 7 (58.3%) and 30 (71.4%) patients of the virus-positive and virus-negative groups (P>0.05). Response rate to intravenous immunoglobulin administration was 67% (n=8) and 86% (n=36) in the virus- positive and virus-negative groups (P>0.05). Conclusion:Respiratory symptoms were commonly observed in KD patients but the association between respiratory viruses and KD were not found. Large multicenter-based investigations are required to confirm the association between acute respiratory viral infections and KD.