• Title/Summary/Keyword: 침투거리

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Surface treatment of polysaccharide by flexible active species generator (플렉서블 활성종 발생기를 이용한 다당류 표면처리)

  • Lee, Yu-Ri;Lee, Seung-Hun;Kim, Do-Geun
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 2018.06a
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    • pp.39-39
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    • 2018
  • 최근 플라즈마 의학이 발달하면서 제트, 펜, 니들, 토치 등의 다양한 형태의 플라즈마 발생기가 개발되었으며 내부의 가스라인으로 가스의 종류, 유속, 조성 등을 조절하여 생물학적 효과를 극대화 할 수 있고 안정적으로 플라즈마 방전상태를 유지할 수 있으나 처리 면적이 좁아 실제 생물학적 시스템 (세포, 조직, 그리고 박테리아) 적용에 있어 한계점이 존재한다. 이러한 한계점을 극복하기 위해서 유전체격벽방전 (Dielectric barrier discharge, DBD) 방식을 이용한 플렉서블 활성종 발생기를 제작하고 생물학적 시스템에 적용하기 위한 방전 특성 평가를 진행하였으며, 간단한 in vitro 모델인 한천 젤을 이용하여 플라즈마 처리에 따른 전달물질의 침투거리를 확인하였다. 플라즈마 방전 시 생성되는 수산화기 [OH], 과산화수소 [$H_2O_2$], 초산소음이온 [$O_2{^-}$], 오존 [$O_3$], 그리고 산화질소 [$NO_x$]와 같은 산소 및 질소 활성종 (Reactive oxygen and nitrogen species, RONS)은 세포벽 또는 세포막의 주요 구성성분인 다당류와 인지질의 과산화 반응을 통해 구조를 변화시키고 생물학적 시스템의 표면의 pH를 낮춘다. 이러한 RONS의 작용은 살균, 소독 뿐만 아니라 약물의 침투를 돕는다. 일반적으로 한천 겔은 농도에 따라 생체 내 뇌 조직과 물리적 특성이 유사하고, 미생물학 기질, 방사선학 연구를 위한 조직모델로 사용되기 때문에 본 연구에서는 3%와 5% 농도의 한천 젤을 사용하여 침투거리를 확인하였다. 한천 젤은 $2.5{\times}2.5{\times}2.5cm^3$의 크기로 준비되었고 대조군으로 염료가 포함된 에멀젼을 0.01 g 도포하고, 실온에서 30분간 보존 후 단면을 잘라 현미경으로 침투거리를 확인하였으며, 실험군으로 플라즈마 전처리 후 에멀젼을 도포한 시표와 에멀젼 도포 후 플라즈마 처리한 시료에 대해 에멀젼 침투거리의 변화를 확인하였다. 본 연구의 플렉서블 활성종 발생기는 인체에 부착하여 사용되기 때문에 화상, 홍반을 유발을 방지하기위해 $40^{\circ}C$의 온도에서 실험을 진행하였고 이때에 플라즈마 방전조건은 $0.065W/cm^2$ 수준의 전력을 소모하는 1.7 kV의 전압, 16 kHz의 주파수로 10분간 처리하였다. 그 결과 3%의 한천 젤의 경우 침투거리 0.779 mm에서 0.826 mm, 0.942 mm까지 침투거리가 증가하였고 5%의 한천 젤의 경우 0.859 mm, 0.949 mm로 증가하였다. 이러한 침투거리 증가는 젤 표면의 다당류를 구성하고 있는 단량체가 플라즈마 처리시 화확적 구조가 끊어져 결론적으로 약물 침투가 증가된 것으로 판단된다.

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Mixing and Penetration Studies of Transverse Jet into a Supersonic Crossflow (초음속 유동 내 공동을 이용한 수직 분사 혼합 및 연료 침투거리에 관한 연구)

  • Kim, Chae-Hyoung;Jeong, Eun-Ju;Jeung, In-Seuck;Kang, Sang-Hun;Yang, Soo-Seok
    • Journal of the Korean Society of Propulsion Engineers
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    • v.12 no.2
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    • pp.24-32
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    • 2008
  • A non-reacting experimental study on a normal injection into a Mach 1.92 crossflow which flows over various geometries(flat plate, small cavity, large cavity) was carried out to investigate the effect of the momentum flux ratio(J). The aft ramp of the cavity advances the increase of the penetration height and the strong two-dimensional shock from recompression region mainly affects the shock structure and mixing layer at the downstream flow. As flow runs downward, the transverse penetration height increases with increasing J(J = 0.9, 1.7, 3.4). However, above some critical ratio, jet penetration height growth with increasing J is not appeared in flow-field. Large scale cavity has a good mixing efficiency but it increases the drag loss in the combustor.

Changes in the force-distance curve of Chinese cabbage leaf-stalk by the type of puncture and cutting probes and their relations to the textural parameters. (탐침의 형태에 따른 배추잎의 힘-거리 곡선의 변화와 조직감과의 상관관계)

  • 윤의정;이철호
    • The Korean Journal of Rheology
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    • v.2 no.1
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    • pp.46-52
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    • 1990
  • 배추의 조직감 특성을 기계적으로 측정하는 방법을 수립하기 위하여 여러 가지 형 태의 탐침에 의한 침투 및 절단시험에서 나타난는 힘-거리 곡선을 비교분석하였으며 그 결 과를 배추잎의 미세구조와 관능적특성과 연관하여 해석하였다. 배추잎의 침투심험에서 탐침 의 선단각, 선단면적 및 둘레에 따라 힘-거리 곡선의 형태는 크게 달라지며 선단면적과 둘 레가 커질수록 파열력이 크게 증대되었다. 절단시험에서는 표피와 내부유관속 조직을 절단 하는 세 개의 특징적인 피크를-나타내었다. 배추잎의 염장에 의하여 침투시험의 최대 변형 력은 크게 감소된 반면 파열력은 크게 증대되어 최대 변형력에 대한 파열력의 비(a/c) 는 증가되었으며 이것은 탐침의 선단면적과 둘레가 큰경우에 더욱 두드러지게 나타났다. 염장 에 의하여 탄성한계까지의 변형거리가 커졌으며 최초 변형에서의 탄성치(a/l)는 감소하는 경 향을 나타내었다. 절단시험에서는 염장에의하여 외피의 절단력이 상대적으로 증가하였다. 배 추 및 절인배추의 아삭아삭한 정도는 침투시험의 최대변형력과 a/l의 변화와 밀접한 관계가 있으며 질긴 정도는 침투시험의 파열력과 a/c 절단시험의 절단력과 관계가 있으며 아작아작 한 정도는 침투시험의 a/c와 관계가 있는 것으로 판단되었다.

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Experimental Study on Fuel-Air Mixing Using Flat Plate/Cavity in Supersonic Flow (초음속 유동장 내 평판/cavity를 이용한 연료-공기 혼합의 실험적 연구)

  • Kim, Jeong-Woo;Jeong, Eun-Ju;Kim, Chae-Hyoung;Jeung, In-Seuck
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2006.11a
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    • pp.319-322
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    • 2006
  • Rapid mixing of air-fuel (<1 ms) is needed to accomplish supersonic combustion. In this experiment, helium was injected laterally in to the Mach 1.92 air flow. 2 kinds of model, flat plate/cavity, were used in this experiment and images were taken by schlieren visualization. Pressure was affected by shock structure in the supersonic duct, and penetration height was increased by increasing J. Penetration height was higher in the cavity model than flat plate model.

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Characteristics of Dual Transverse Injection in Supersonic Flow Fields I-Mixing Characteristics (초음속 유동장 내 이중 수직분사의 특성에 관한 연구 I-혼합특성)

  • Shin, Hun-Bum;Lee, Sang-Hyeon
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.30 no.6
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    • pp.53-60
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    • 2002
  • Based on the analyses of the single transverse injection in supersonic flow fields, the mixing characteristics of dual transverse injection of hydrogen in supersonic air flow are studied with computational methods. Three-dimensional Navier -Stokes and the k-$\omega$ SST turbulence model were used. A parametric study is conducted with the variation of the distance between two injectors. The flow patterns and the mixing characteristics of two injection flows are very different from each other, and the flow patterns and the mixing characteristics of the rear injection flow are strongly influenced by those of the first injection flow. The increase of the distance between two injectors up to a specific distance results in the increase of mixing rate and penetration of fuel. However, the increase of the distance over the specific distance results in the decrease of mixing rate and penetration of fuel. From the results it can be stated that there exists a distance between two injectors for optimum mixing characteristics.

Penetration Height of Low-temperature Ethanol Jet Injected Into a Crossflow Airstream (횡단 공기유동장으로 분사되는 저온 에탄올 제트의 침투거리)

  • Lee, Jongkwon;Koo, Jaye
    • Journal of ILASS-Korea
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    • v.25 no.2
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    • pp.74-80
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    • 2020
  • The jet in crossflow is a spray method used in the various air-breathing engine. In order to understand the spray characteristics in various environments, many prior studies have been conducted. However, there is a lack of understanding of the low-temperature liquid spray characteristics below 273 K. With this in mind, we tried to enhance the knowledge of the low-temperature liquid spray characteristics by identifying the penetration height of low-temperature ethanol. The experiment was conducted under phase pressure, and 273 K of air and 293, 263, and 233 K of ethanol was used. Shadowgraphy was employed to measure the liquid penetration, and Otsu's method was used to analyze the penetration height. The heights tend to decrease as the temperature of the liquid jet decreases. A correlation for the penetration height in the experimental conditions was derived and presented.

Study on Penetration Performance of Precision Linear Shaped Charge (정밀선상성형장약의 침투·관통 성능에 관한 연구)

  • Lee, Si-Eun;Lee, Juho;Moon, Mi-Ae
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.47 no.6
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    • pp.397-404
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    • 2019
  • Linear Shaped Charge (LSC) that is widely used as separation system in aerospace system has to charge lots of explosives due to lack of uniformity. In addition, it is hard to optimize shape of liner and explosives because of manufacturing process. In order to overcome aforementioned drawbacks, Precision Linear Shaped Charge (PLSC) is currently under development. PLSC is made in two steps: prepare liner independently and charge explosive uniformly. In this study, PLSC is designed to have proper amount of explosives and penetration test of PLSC with different stand-off distance from liner to target is conducted to confirm penetration performance. Based on the penetration test results of PLSC, the numerical analysis method using AUTODYN is established and verified. Penetration mechanism and characteristics of PLSC is analyzed from the numerical and experimental results.

Assessment of Available Coastal Groundwater Resources Using Strack's Single-potential Analytical Solution (Strack의 단일 포텐셜 해석해를 이용한 해안지하수 개발가능량 평가)

  • Cui, Lei;Lee, Chang-Hae;Park, Nam-Sik
    • Journal of Korea Water Resources Association
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    • v.41 no.1
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    • pp.27-34
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    • 2008
  • Groundwater development in coastal areas induces saltwater intrusion. In many cases amount of groundwater resources available for development is limited by a pre-specified limit of additional saltwater intrusion. In this paper a simple equation is developed to assess available groundwater resources which depends on the constraint of acceptable additional saltwater intrusion. Strack#s single-potential analytical solution is used to derive the equation. Available groundwater increases as more additional intrusion is allowed. However, critical points limit both the maximum pumping rate and the allowed saltwater intrusion limit. The equation is presented in the form of design curves from which the maximum pumping rate can be read off quickly. The equation and the design curves are suitable for preliminary estimation of available groundwater resources in coastal areas.

A Study on Clogging and Water Quality Improvement in Floodplain Filtration with Flood/rest Raw-water Supply (범람/휴지식 홍수터여과에서 폐색현상 및 수질개선도 연구)

  • Kim, Hoh-Seok;Kim, Seung-Hyun
    • Journal of Korean Society of Environmental Engineers
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    • v.33 no.2
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    • pp.120-131
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    • 2011
  • A pilot-scale experiment of floodplain filtration with a filtration depth of 3.6m was performed employing flood/rest type raw-water supply system in an effort to find ways to improve river water quality by additional treatments of discharged effluent from sewage treatment plant. Soil samples were taken from 3 sites including Gumi, Daegu and Gimhae along the Nakdong river. Reductions of infiltration rates following increases in operating time was investigated in each soil sample, along with the analysis of removal efficiencies of various pollutants according to different depths and infiltration rates. The results show incremental development of clogging on the soil surface with increases in operation time, and illustrate exponential decrease in the infiltration rate. The time required for the removal of the clog from the soil surface was longer than 2 weeks for all soil samples analyzed. The stable infiltration rates for soils were 5 m/day for Gumi and for Daegu and Gimhae was 1 m/day. In unsaturated soils dissolved oxygen levels increased following the increase of filtration depth, suggesting that alternating application of flood and rest for raw-water supply effectively keeps the soil environment aerobic. For all soils, the nature of pollutant removal depending on the depth of filtration remained the same regardless of the infiltration rate. Most of the BOD and turbidity were removed within 1.2 m, about 30% of COD was removed within 3.6m and was expected to be removed further with increases in filtration depth. Nitrification occurred near the surface of all soils; however there was no significant removal of nitrogen in the filtration depths tested in this study. Although removal rate of phosphorus was low for Gumi's soil, it was high enough for other soils, suggesting that the method developed in this study could significantly improve river water quality.