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A Case Report of Irritable Bowel Syndrome Treated with Daechilgitang-gagambang (과민성대장증후군 환자의 대칠기탕가감방(大七氣湯加減方) 임상보고)

  • Lee, Ju-Il;Park, Young-Chul;Kwon, Do-Ik;Sun, The-Cheng;Kim, Ju-Young;Park, Jun-Ha;Hong, Eun-Ki
    • The Journal of Korean Obstetrics and Gynecology
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    • v.20 no.1
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    • pp.268-276
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    • 2007
  • Purpose : The purpose of this study is to report the effect of oriental treatments for Irritable Bowel Syndrome. Methods : We treated a 57 - year - old female who had severe abdominal pain and discomfort companied by alteration in bowel function, a combination of diarrhea and constipation, with Herb medication ( Daechilgitang-gagambang )and acupuncture therapy at the same time. Results : After oriental medical treatment, the clinical symptom of Irritable Bowel Syndrome was improved. Conclusion : This case study shows that the oriental medical therapy is effective in treating irritable bowel syndrome. So that, it is helpful in decreasing the symptoms of patients and in improving quality of life.

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The Anti-cancer Effects of Bigihwan, Daechilgithang, and Mokwhyangbinranghwan Ethanol Extracts in Human Hepatocellular Carcinoma Cells (인체 간암세포에서 비기환(肥氣丸), 대칠기탕(大七氣湯) 및 목향빈랑환(木香檳榔丸)의 항암 활성 비교)

  • Kim, So Young;Hong, Su Hyun;Choi, Sung Hyun;Cheong, JaeHun;Choi, Yung Hyun
    • Journal of Life Science
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    • v.30 no.5
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    • pp.460-467
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    • 2020
  • Hepatocellular carcinoma (HCC) is one of the most commonly diagnosed cancers in the word. Although radiation and chemotherapy are generally effective, there are various side effects that greatly limit the effectiveness of these treatments. Therefore, traditional herbs may have potential as important resources for the discovery of liver cancer therapeutics. In this study, we selected three Korean herbal medicine formulas from the Donguibogam, namely Bigihwan (BGH), Daechilgithang (DCGT), and Mokwhyangbinranghwan (MHBRH), and evaluated their anti-cancer effects on HCC cells. According to our results of three ethanol extracts, BGH was more effective at suppressing HCC growth than DCGT or MHBRH. Furthermore, flow cytometry analysis showed that inhibition of HCC proliferation by the three extracts was associated with the induction of apoptosis and autophagy. In particular, BGH significantly increased mitochondrial impairment and showed the possibility of inducing mitophagy in comparison with the other two extracts. BGH prominently upregulated the levels of microtubule-associated protein light chain-3 which was accompanied by a decrease in the expression of anti-apoptotic Bcl-2 without altering the expression of pro-apoptotic Bax. In addition, the levels of PTEN-induced kinase 1 were also markedly increased in BGH-treated HCC cells. Moreover, autophagy blocking improved cell viability and reduced apoptosis after the three treatments, indicating that autophagy by these extracts enhances HCC cells against cytotoxicity. In conclusion, our findings show that BGH demonstrates the highest anti-cancer activity among the three formulas and inhibits the proliferation of HCC cells through autophagy induction.

Study on Analysis of manufacturing technique and Materials used for Lacquerware artifacts with focus on Joseon Dynasty Records, Uigwe (조선왕실 의궤를 통해 본 옻칠 공예품 제작 방법 및 사용 재료 연구)

  • Kim, Jin Ok
    • 보존과학연구
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    • s.32
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    • pp.53-60
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    • 2011
  • The aim of this study is to investigate the traditional manufacturing technique of lacquering by comparing and analyzing materials used for wooden lacquerware artifacts with focus on the Joseon dynasty Eugye, and to apply the manufacturing technique to the conservation treatment of the lacquerware. artifacts. This study conducted the documentary survey focusing on "Yongjo Jeongsun Queen Consort Garye Dogam Eugye",and "Jeongjo Gukjang Dogam Eugye." The royal lacquering is roughly classified into three categories-scarlet lacquering, quality black lacquering, and terra rosa lacquering- according to materials used for lacquerware. The bean flour was mostly used for under lacquering of the articles which was offered to the king and in case of other articles, bean flour was used mixed with bone ashes. In some cases, burned pine soot was added to under lacquering. Japanese scarlet lacquering was applied by mixing maechil-main coat, in inverted commas- with Japenese scarlet after lacquering jeonchil-base coat, in inverted commas-. In case of Chinese scarlet lacquering, part of terra rosa was used mixed with red clay. For quality black lacquering, basically jeonchil and maechil were used, but sometimes part of burned pine soot was added. In addition, terra rosa lacquering was applied by basically using terra rosa mixed with red clay. Lastly, gloss was given by using perilla oil. It is expected that the traditional materials and technique examined through both documentary and relic research will contribute to advanced result of the conservation treatment of wooden lacqueringware artifacts.

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Lacquer as Adhesive : Its Historical Value and Modern Utilization (접착제로서의 옻; 역사성과 현대적 활용)

  • Jang, Sung Yoon
    • Korean Journal of Heritage: History & Science
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    • v.49 no.4
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    • pp.114-125
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    • 2016
  • Lacquer is one of the most widely used natural resin in East Asia since Neolithic Age. As a major ingredient of lacquerware, lacquer is waterproof, insect-proof and rot-proof to be durable and anti-abrasion, generally utilized for mainly painting purpose. According to lacquerware excavated from several sites of Japan and China, lacquerware seems to appear in Neolithic Age. On the other hand in case of excavation research in Korea, lacquerwares are found after the Bronze Age. The initial purpose of lacquer is estimated to be adhesive, regarding the literatures mentioning bitumen(Yeoksceong ), animal glue(Kyeo) and egg alumen(Nanbaek). Especially piece of jar coffin unearthed in Pyeongtaek Daechu-ri site had trace of restoration by lacquer and hemp as an evidence of lacquer for adhesion in Pre-Three Kingdoms period. Since then a trend to restore the broken ceramics with lacquer and decorate with golden foil lasted especially in Joseon Dynasty. In the field of gold plated lacquer method, mother-of-pearl inlaying technique for lacquerware and restoration of buildings, lacquer is still used as adhesive. Due to matter of reversibility lacquer is being avoided for conservation and restoration of cultural heritage. Lacquer as a traditional material for adhesive since ancient times, however, has advantage in adhesion strength and durability. Because synthetic resin adhesive has problem of emission of volatile organic compounds and aging over time, lacquer receives attention recently. On the contrary, by combination adhesive from mixing lacquer and animal glue, already proved the possibility of applicability and chemical modification. A research to utilize lacquer as modern paint or functional material is also conducted continuously also in China and Japan. To put traditional material into practical use and modernize, chemical research from the molecular level of the lacquer is necessary in the near future.

A Study of Making Semiconductor Production Plan using LP Algorithm (LP Algorithm을 이용한 반도체 생산 계획의 도출)

  • Park Dong-Sik;Lee Jee-Hyong;Yu Kwan-Ho;Lee Chil-Gee
    • Proceedings of the IEEK Conference
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    • 2004.06b
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    • pp.481-484
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    • 2004
  • To make production and equipment investment plans in semiconductor Line, implementation of many variables is needed. But these factors could bring many changes and the result is hard to predict. Because prediction is hard, it is hard to make a standard. So this project established Semiconductor production plans using LP Algorithm to satisfy all the conditions from the factors and came up with thesis on reasonable and standardized process.

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Conveyor Capability Simulation for Semiconductor Diffusion Area (반도체 Diffusion Area에서의 Conveyor Capability Simulation)

  • 박일석;한영신;이칠기
    • Proceedings of the Korea Society for Simulation Conference
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    • 2002.05a
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    • pp.145-149
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    • 2002
  • 92∼3년 A 라인에서 처음으로 Bay 내에 Conveyor (Intra) 사용한 Stocker to Equipment에서 Material(Lot) Moving을 위한 Project를 실시하였으나 예상과는 달리 Conveyor Capability가 부족하여 장비에서 Rundown 현상이 발생하였다. 정상적인 Simulation없이 Design한 Conveyor System은 막대한 금전투자, 인력투자, 설치Testing 철거 등으로 인한 라인 작업방해 등 막대한 손실을 남기는 실패를 가져왔다. 본 연구에서는 이미 장비가 Setup되어 Running중에 있는 반도체 라인 환경 또는 신규로 새로운 라인을 Design할 때 사람을 대신하여 Bay내에서 Lot을 Stocker에서 장비 또는 장비에서 장비로 이동을 Conveyer를 사용할 경우 적정 Conveyor Capability를 산정 하는데 그 목적이 있다.

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Simulation for Efficient Employment of JLBS (JLBS의 효율적인 운용을 위한 시뮬레이션)

  • 남동진;한영신;이칠기
    • Proceedings of the Korea Society for Simulation Conference
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    • 2002.05a
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    • pp.183-187
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    • 2002
  • JLBS는 multi-server multi-queue 방식을 채택하고 있으며, 각 tool별로 할당된 license 수에 비례하여 system을 할당한다. 그러나 이러한 방식의 문제점은 특정 tool에만 job이 집중될 경우 비효율적이다. 즉 특정 system은 모두 사용되고 있고, queue에는 많은 job이 대기하고, 여타 tool에 해당하는 queue에는 대기하는 job이 없어서 system이 그냥 놀고 있는 현상이 발생한다. 본 논문에서는 이러한 단점을 극복하기 위해 각 tool에 license수에 비례하여 할당되었던 system을 모든 tool들이 system을 공유할 수 있도록 하는 방법을 제안했다. 대신 system의 숫자는 줄이고, license의 숫자는 더 할당하는 방법으로, 기존의 방법보다 더 효율적으로 나타났다.

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Automatic classification of failure patterns in semiconductor EDS Test using pattern recognition (반도체 EDS공정에서의 패턴인식기법을 이용한 불량 유형 자동 분류 방법 연구)

  • 한영신;황미영;이칠기
    • Proceedings of the IEEK Conference
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    • 2003.07b
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    • pp.703-706
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    • 2003
  • Yield enhancement in semiconductor fabrication is important. It is ideal to prevent all the failures. However, when a failure occurs, it is important to quickly specify the cause stage and take countermeasure. The automatic method of failure pattern extraction from fail bit map provides reduced time to analysis and facilitates yield enhancement. This paper describes the techniques to automatically classifies a failure pattern using a fail bit map, a new simple schema which facilitates the failure analysis.

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Computation of the Acoustic Field in Benchmamark Wedge Medium by Image Model (영상 모델에 의한 표준쐐기 매질내의 음장 계산)

  • 백칠기;장지원
    • The Journal of the Acoustical Society of Korea
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    • v.12 no.6
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    • pp.45-52
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    • 1993
  • 1986년 미국 음향학회 수중음향학술분과 특별회기중에 제안된 표준쐐기형 매질내의 음장을 계산하기 위하여 영상모델이 사용되었다. 음장의 계산 결과는 왕복결합모드무델과 음선모델에 의한 계산 결과들과 비교되었다. 영상모델은 그 특성에 의한 제한점을 갖고 있으나, 표준 쐐기형 매질의 음장 계산에 사용될 수 있고, 기존의 수치모델과는 달리 개인용 컴퓨터로써 쐐기형 매질의 음장 계산이 가능하기 때문에 음파 전파 현상분석 등의 연구에 유용하게 사용될 수 있다.

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