• Title/Summary/Keyword: 치수생성

Search Result 115, Processing Time 0.037 seconds

The Effects of Porphyromonas endodontalis Lipopolysaccharide on Production of Several CC Chemokines by Periodontal Ligament Fibroblast (Porphyromonas endodontalis의 lipopolysaccharide가 치주인대 섬유아세포의 CC Chemokines 성성에 미치는 영향)

  • KO Hyun-Jung;Lee Sang-Yup;Lee Woo-Chul;Baek Seung-Ho;Bae Kwang-Sik;Lim Sung-Sam
    • The Journal of the Korean dental association
    • /
    • v.43 no.12 s.439
    • /
    • pp.799-808
    • /
    • 2005
  • 이 연구의 목적은 치수 및 치근단 조직의 감염의 주요 원인들이 Porphyromonas endodontalis의 LPS가 치주인대 섬유아세포의 MCP-1 MIP-1α 그리고 RANTES의 생성에 미치는 영향을 관찰함으로써 치근단 염중의 발병에서 섬유아세포의 역할을 알아보는 것이다. 혐기성 조건에서 배양한 P. endodontalis와 E. coil의 LPS를 추출, 정제한 후, 치주인대 섬유아세포 0.01, 0.1, 1, 10ug/ml 농도의 P. endodontalis와 E. coil의 LPS로 12, 24, 48시간 동안 자극하였다. MCP-1, MIP-1α 그리고 RANTES의 단백질 농도는 ELISA를 이용하여 분석하였다. 이연구의 결과는 아래와 같다. 1. P. endodontalis의 LPS로 자극시킨 치주인대 섬유아세포에서 분비된 MCP-1의 수준은 시간과 농도에 비례하여 증가하였다. 2.E.coil의 LPS로 자극시킨 치주인대 섬유아세포에서 분비된 MCP-1의 양도 시간에 비례하여 증가함을 보였다. 이는 P. endodontalis LPS보다 통계적으로 유의성있게 많은 양을 나타냈다.(p<0.05) 3. 치주인대 섬유아세포에서 MIP-1α 과 RANTES는 거의 분비되지 않았다. 이 연구에서 세균의 LPS로 자극시 치주인대 섬유아세포 MCP-1의 강한 발현은 만성 치근단 염증의 초기에 단핵세포와 대식세포의 recruitment를 증가시키는 것고 관련되어지는 것으로 보인다.

  • PDF

An Algorithm for Automatic Generation of Dimension and Tolerance Charts (치수/공차표의 자동생성 알고리듬)

  • Jung, Jong-In;Kim, Kwang-Soo;Choi, Hoo-Gon
    • Journal of Korean Institute of Industrial Engineers
    • /
    • v.29 no.1
    • /
    • pp.21-31
    • /
    • 2003
  • Determination of operational dimensions and tolerances is complex if there exist inconsistencies between operational and design specifications. Dimension and tolerance charts (D&T charts) have been used to establish the relationships among operational dimensions in complex machining. This chart proves that individual operations can be harmonized when they are interconnected. However, it is hard to generate the chart manually. Because operational dimensions and tolerances must meet the design specifications, the dimensions and tolerances of interconnected operations have to be verified serially for economical operations. In this paper, the chart is automatically generated from the interconnected operations. More importantly, all operational dimensions and tolerances displayed in the chart have been verified by using LP to meet the design specifications. Finally, the chart is converted to an operational routing sheet that contains a detailed process plan along with cutting speed, feed rate, and operational references based on material hardness, surface finish, and tool nose radius.

Novel Preparation of Epoxy/Silica Nanocomposite Using Si-N Precursor (Si-N 전구체를 이용한 에폭시/실리카 나노복합재료의 제조)

  • Kim Lee Ju;Yoon Ho Gyu;Lee Sang-Soo;Kim Junkyung
    • Polymer(Korea)
    • /
    • v.28 no.5
    • /
    • pp.391-396
    • /
    • 2004
  • In order to overcome drawbacks in the conventional preparation of epoxy/silica nanocomposites, such as formation of micro voids and dimensional instability caused by evolution of volatile by-products during curing reaction, a novel preparation method using Si-N precursor has been proposed. When prepared through in-situ reaction of epoxy curing reaction with sol-gel reaction of Si-N precursor, methyltripiperidinylsilane (MTPS) which does not produce by-products during reaction, epoxy/silica nanocomposites of extremely even dispersion of inorganic phase could be successfully prepared, resulting in high enhancement of mechanical and thermal properties as well as outstanding transparency.

New evaluation chart of stature and weight for Koreans (한국인 키 및 몸무게 신 평가표에 관한 연구)

  • Lee, Shin-Jae;Kim, Young-Jae;Kim, Tae-Woo;Ahn, Sug-Joon
    • The korean journal of orthodontics
    • /
    • v.36 no.2 s.115
    • /
    • pp.153-160
    • /
    • 2006
  • For orthodontic treatment of growing patients and those which involve long treatment times, knowledge of growth and development are essential. Data from the general growth observation chart being used at present does not reflect the growth transition of modern times. This is because these data are out of date. The present study, therefore, aims to introduce the process of producing a growth curve and growth rate curve based on data which represents a more accurate description of the present situation. The data used were from the 5th nationwide surrey, SIZE KOREA 2004 study, carried out by the Technology and Standards Policy Division, Department of Technology and Standards Planning, Ministry of Commerce. Processing and rearranging produced data with variations divided into the three quartiles and the 1st, 5th, 95th and 99th percentiles were included to produce a growth observation chart according to sex, height and weight differences. In the same way, a growth rate curve based on the geometric mean value was produced. The resulting growth charts can be used as an index for growth and development, and used for better communication between the orthodontist, patients and parents.

EVALUATION MODEL OF GROWTH AND DEVELOPMENT IN PEDIATRIC DENTISTRY (한국인 소아의 성장 발육 평가 자료 제작에 관한 연구)

  • Kim, Young-Jae;Lee, Shin-Jae;Kim, Jung-Wook;Jang, Ki-Taeg;Lee, Sang-Hoon;Hahn, Se-Hyun;Kim, Chong-Chul
    • Journal of the korean academy of Pediatric Dentistry
    • /
    • v.33 no.2
    • /
    • pp.173-180
    • /
    • 2006
  • Knowledge of growth and development is essential for pediatric dentistry treating growing patients. The data from the pediatric growth curve being used today does not reflect the growth transition of modern times, nor does it match the age range required for dental purposes. The present study, therefore, aims to introduce the process of producing a growth curve and growth rate curve based on data which represents a more accurate description of the present situation. The original data used in this study were from the 5th nationwide survey, SIZE KOREA 2004 study carried out by the Technology and Standards Policy Division, Department of Technology and Standards Planning, Ministry of Commerce, Industry. and Energy. Processing and rearranging the produced data with variations divided into the three quartiles and the 1st, 5th, 95th and 99th percentiles were included to produce a growth observation chart according to sex, height and weight differences. In the same way, a growth rate curve based on the geometric mean value was produced. The resulting growth charts can be used as an index for growth and development, and used for better communication between the pediatric dentist, patients or their parents.

  • PDF

The Simulation of Flood Inundation of Namdae Stream with GIS-based FLUMEN model (GIS 기반 FLUMEN 모형을 이용한 남대천 홍수범람 모의실험)

  • Lee, Geun-Sang;Choi, Yun-Woong
    • Spatial Information Research
    • /
    • v.18 no.2
    • /
    • pp.25-34
    • /
    • 2010
  • This study simulated flood inundation each frequency rainfall using GIS spatial information and FLUMEN model for part of Muju-Namdae Stream. To create geomorphology for the analysis of flood inundation, Triangle Irregular Network(TIN) was constructed using GIS spatial interpolation method based on digital topographic map and river profile data, unique data source to represent real topography of the river areas. And also flood inundation was operated according to the levee collapse to consider extremely flood damage scenarios. As the analysis of result, the inundation area in the left levee collapse showed more high as 3.13, 3.69, and 4.17 times comparing with one of right levee for 50, 100, and 200 year frequency rainfall and showed 1.00, 2.15, and 3.34 times comparing with one of right levee in the inundation depth with over 1.0 meter, which can cause casualties. As the analysis of inundation area of the inundation depth with over 1.0 meter, which can cause casualties in left levee collapse, it increased more high as 263% and 473% when 50 year frequency change into 100 and 200 year frequency. Also As the analysis of inundation area of the inundation depth with over 1.0 meter in right levee collapse, it increased high as 123% and 142% when 50 year frequency change into 100 and 200 year frequency. Especially, the inundation area of the inundation depth with 3.0~3.5m showed more high as 263% and 489% when 50 year frequency change into 100 and 200 year frequency. It is expected that flood inundation map of this paper could be important decision making data to establish land use planning and water treatment measures.

Development of the Integrated Water Resources Index based on characteristic of indicators (세부지표 특성을 고려한 수자원통합지수 개발)

  • Choi, Si-Jung;Lee, Dong-Ryul;Moon, Jang-Won;Kang, Seong-Kyu;Yang, So-Hye
    • Proceedings of the Korea Water Resources Association Conference
    • /
    • 2011.05a
    • /
    • pp.456-456
    • /
    • 2011
  • 국내에서는 1999년부터 국가수자원관리종합정보시스템(WAMIS) 구축 및 운영을 통해 물관리정보화사업을 추진하고 있으며 기초정보분석 중심에서 수자원 계획 수립과 정책 결정을 지원할 수 있는 시스템으로 확대하여 대국민 수자원 정보 제공과 홍보를 활성화하려고 노력하고 있다. 하지만 지금까지 국내에서는 수자원 현황을 평가하기 위해 상수도보급율, 하천개수율 등을 이용하여 수자원의 단편적인 분야만을 평가하여 왔으며 이들 개별지표들만으로 국내 수자원 상황에 대해 국민들이 체감하는데 한계가 있어 이들 사업의 성과를 지수화하여 수자원 정책과 사업의 효과를 국민들에게 적극적으로 홍보할 필요가 있다. 이를 지원하기 위해 2007년부터 2009년까지 수자원 각 분야별 수자원계획수립 업무지원체계를 구축하였으며 수자원 현황 평가를 위해 분야별 평가지수를 개발하고 수자원 통합지수를 선정하여 중권역별로 산정한 바 있다(건설교통부, 2007; 국토해양부, 2008, 2009). 보다 합리적인 수자원 평가를 위해서는 분야별(물이용, 치수, 하천환경) 평가 지수의 공간적 범위 확대 및 세부지표를 추가 고려함으로써 과거에서부터 현재까지의 분야별 변화 패턴을 파악해야 한다. 이를 통해 수자원 관련 정책 및 사업의 성과를 평가하고 구축된 기초자료 및 분석정보를 제공해 줄 수 있는 도구의 개발이 무엇보다 중요하다고 하겠다. 따라서 본 연구에서는 기 개발된 분야별 평가지수 산정 결과와 분야별 현황과의 비교 분석을 통해 지수의 현장 적용성을 검토함으로써 기 개발된 지표의 취약점 및 한계점을 제시하였다. 보다 합리적이고 타당한 분야별 평가를 위해 세부지표를 추가로 선정하였으며 선정된 분야별 세부지표를 PSR 구성체계에 맞추어 구성하였다. 또한 분야별 현황 및 특성을 평가할 수 있는 분야별 평가지수를 개발하였으며 물이용 특성을 평가할 수 있는 지수를 '물이용안전성지수', 치수 특성을 평가할 수 있는 지수를 '홍수안전성지수', 하천환경 특성을 평가할 수 있는 지수를 '하천환경건강성지수'라 명명하였다. 또한 분야별 평가지수를 통합하여 수자원 현황을 평가하고 관리할 수 있는 수자원 통합지수인 '물만족지수'를 개발하여 제시하였다. 분야별 평가지수를 구성하는 각 세부지표의 특성을 파악하여 지표 산정 범위를 점, 선, 면으로 확대하여 제시하였으며 세분화된 공간단위별로 기초자료를 조사, 수집하여 시계열 DB를 구축하였다. 개발된 분야별 평가지수 및 물만족지수를 연도별 표준유역별로 구축된 DB를 이용하여 산정하고 비교 분석하였으며 상대적인 분야별 안전성 및 건강성을 평가하여 지수의 적용성을 검토하였다. 지표 관련 기초자료 및 분석을 통해 생성된 정보자료는 수자원정책 수립과정에서 매우 유용한 정보를 제공해 줌으로써 정책결정을 지원할 수 있고, 일반인과 관련 전문가들에게 수자원 관련 다양한 정보를 제공할 수 있다.

  • PDF

A Multiobjective Genetic Algorithm for Static Scheduling of Real-time Tasks (다목적 유전 알고리즘을 이용한 실시간 태스크의 정적 스케줄링 기법)

  • 오재원;김희천;우치수
    • Journal of KIISE:Software and Applications
    • /
    • v.31 no.3
    • /
    • pp.293-307
    • /
    • 2004
  • We consider the problem of scheduling tasks of a precedence constrained task graph, where each task has its execution time and deadline, onto a set of identical processors in a way that simultaneously minimizes the number of processors required and the total tardiness of tasks. Most existing approaches tend to focus on the minimization of the total tardiness of tasks. In another methods, solutions to this problem are usually computed by combining the two objectives into a simple criterion to be optimized. In this paper, the minimization is carried out using a multiobjective genetic algorithm (GA) that independently considers both criteria by using a vector-valued cost function. We present various GA components that are well suited to the problem of task scheduling, such as a non-trivial encoding strategy. a domination-based selection operator, and a heuristic crossover operator We also provide three local improvement heuristics that facilitate the fast convergence of GA's. The experimental results showed that when compared to five methods used previously, such as list-scheduling algorithms and a specific genetic algorithm, the Performance of our algorithm was comparable or better for 178 out of 180 randomly generated task graphs.

Influences of Vegetation Invasion on Channel Changes in the Deposition Area of Torrential Stream (계상퇴적지내의 식생침입이 유로변동에 미치는 영향)

  • Ma, Ho-Seop;Lee, Heon-Ho
    • Journal of the Korean Society of Environmental Restoration Technology
    • /
    • v.3 no.3
    • /
    • pp.12-19
    • /
    • 2000
  • The purpose of this study is to evaluate the channel changes according to the temporal and spatial distribution of the deposition area by the vegetation invasion in Kyesung-river. The deposition area mainly occurred by landslide and debris flow from the headwater channel. And also the movement of subsequent downstream depends upon the site of deposits by a varity erosional processes. As the age of deposition area is older, it had a tendency to stable by plant invasion relatively. The vegetations grown in deposition area were very effective to estimate a historical deformation process of river-bed occurred by landslide. The vegetations around deposition area consisted of the same as tree species grown in forest area of circumference like Pinus densiflora, Styrax japonica, Quercus acutissima and Salix gracilistyla. If the torrential stream is flooding, the deposition area of 1 to 5 years can be change to the channel easily. Deposition area of 11 to 23 years had a high river-bed because it passed long time since deposited, and amount of sedimention is much more in wide than in narrow channel. It is consider that the change of channel had many influenced by the span of survial time, scale and movement frequency of deposition area after the vegetation invasion.

  • PDF

Preform Design of a Forged Punch by Approximate Optimization (근사 최적화 기법을 이용한 펀치 단조품의 예비성형체 설계)

  • Park, Sangkun
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.15 no.7
    • /
    • pp.4057-4064
    • /
    • 2014
  • In this paper, attempts were made to design a preform for a final punch inexpensively using the proposed approximate optimization method or metamodel-based simulation optimization. The design objective of this work is to achieve a uniform distribution of effective strains, the angle dimension of the preformed punch is chosen as a design variable, and maximum underfill ratio is used as a constraint. For this optimization, a computer simulation of a practical punch forging process is run using DEFORM software, in which a preformed punch(workpiece), a master punch(upper die), and a bottom die are dealt with. A validation method is introduced to determine if the simulation results match the actual forging process. In addition, this work presents the detailed design optimization procedure consisting of (i) generation of an initial metamodel, (ii) metamodel optimization, (iii) validation of metamodel-predicted optimum, and (iv) metamodel improvement.