• 대한임상독성학회지
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• 제10권2호
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• pp.111-117
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• 2012

Purpose: In Korea, few studies have examined the acute toxicity of anti-obesity drugs. The purpose of this study is to analyze the general characteristics and clinical aspect of acute anti-obesity drug intoxication. Methods: We retrospectively investigated patients admitted to the emergency department after anti-obesity drug intoxication between March, 2004 and February, 2012. The medical records of these patients were reviewed for demographic data, toxicologic history, time elapsed to presentation, clinical symptoms and signs, treatment, and outcome. Results: There were a total of 18 anti-obesity intoxication cases during the study period; of 16 which were included in our study. The purchasing route of the anti-obesity drug was mainly through a doctor's prescription (68.8%), however, some were obtained through the internet and the pharmacies. The mean time to The most commonly ingested antiobesity drug was sibutramine (31.3%) and many of the cases (62.5%) were multi-drug ingestions. The most common clinical manifestations were gastrointestinal symptoms (94%), but, CNS symptoms (75%) and cardiovascular symptoms (75%) were almost equally present. 13 patients (81%) were discharged after clearance of toxic symptoms and signs with a mean observational period of 7.0 hours. 3 patients were admitted for observation and treatment; of which 1 patient died due to fatal complications. Conclusion: Most anti-obesity intoxications show mild toxicity and a nonfatal clinical course. However, the recent trend toward prescribing psychostimulant anti-obesity medication, which can be fatal after an acute overdose, calls physicians' attention to treating of anti-obesity intoxications.

• 대한암한의학회지
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• 제16권1호
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• pp.15-31
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• 2011

Objective : The study aims to investigate the effect of moxibustion treatments on autonomic nervous system function of cancer patients through the evaluation of heart rate variability (HRV) biofeedback testing. Materials and Methods : Six cancer patients from inpatient care unit of Dunsan Oriental Hospital, Daejeon University were given three moxibustion treatment sessions every other day over one week period on five Oriental Medicine meridian points CV4, CV6, CV12, KD1, and PC8. HRV biofeedback was conducted before and after each treatment sessions. Three areas of analyses were done from the test conducted; Time Domain Analysis, Frequency Domain Analysis and Autonomic Nervous System (ANS) balance analysis. Results : Time Domain Analysis has shown increased Standard Deviation of all Normal R-R Intervals (SDNN), and decreased Mean Heart Rate and Physical Stress Index (PSI) levels, with statistical significance (P<0.05). In Frequency Domain Analysis, series of moxa treatments have increased Total Power (TP), Very Low Frequency Oscillation Power (VLF), High Frequency Oscillation Power (HF), normalized HF values while decreasing Low Frequency Oscillation Power (LF), normalized LF and LF/HF ratio with statistical significance (P<0.05). The values of ANS activity, ANS balance, Stress resistance, Stress index, have also shown significant changes. For cardiac stability stroke volume power (SP) and Blood Vessel Tension (BVT) were followed, which were both increased after treatment. All changes were statistically significant (P<0.05). Conclusion : The results have shown a positive correlation between the moxibustion treatments and autonomic nervous system responses on cancer patients through the HRV biofeedback testing. This study suggests possible application of moxibustion treatments for managing ANS functions of cancer patients, although additional studies with larger population are necessary to confirm the data.

• Journal of Chest Surgery
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• 제34권7호
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• pp.566-568
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• 2001

잘 분화된 태아성 선암종은 조직학적으로 폐모세포종과 유사하여, 폐모세포종의 한 분류로 생각되어지며, 육종성 형태와 상피성 형태 사이의 태아성 폐에 유사한 상피성 형태를 보인다. 최근 저자등은 19세 남자 환자에서 폐의 좌상엽 부위에 발생한 종괴에 미세 흡침 조직 검사상 폐모세포종으로 나와 좌상엽 절제술을 시행하였고, 술 후 시행한 조직 검사상 육종성 형태는 없었으며, 잘 분화된 태아성 선암종으로 확진되어 문헌고찰과 함께 보고하는 바이다.

• Journal of Chest Surgery
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• 제41권4호
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• pp.512-515
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• 2008

폐분획증이 없는 좌측 바닥 구역의 이상 기시 체혈관은 폐분획증의 범주 안에 속하는 매우 드문 선천성 질환이다. 하지만 폐분획증과는 달리 정상적인 기관지 연결 관계를 가지고 있다. 술전에 진단된 폐분획증이 없는 좌측 기저 분엽의 이상 기시 체혈관에 대한 수술적 치료를 치험하였기에 이를 보고 하고자 한다.

• 보건교육건강증진학회지
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• 제33권1호
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• pp.23-32
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• 2016

Objectives: The aim of this study was to examine the effects of home-based cognitive physico-occupational therapy(HBCPOT) on cognitive function, depression, and quality of life in dementia patients, using a cognitive impairment model. Methods: The data was analysed for Mini-Mental State Examination-Korean version (MMSE-KC) for assessing cognitive function, Quality of life-Alzheimer's Disease (QOL-AD) and Geriatric Depression Scale (GDS) in 31 dementia patients who received home-based cognitive physico-occupational therapy for one hour once a week for 12 weeks by a trained occupational therapist at the Dementia Prevention and Management Center of Y-city during 20111-2013. Results: Among these 31 patients, 18(58.1%) were female, and 25(80.6%) had Alzheimer's Disease. After HBCPOT, the mean scores of MMSE-KC and QOL-AD were significantly improved, but GDS score was not significantly decreased. Conclusions: It was suggested that HBCPOT was effective in improving cognitive function and quality of life.

• 한국정보통신학회논문지
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• 제16권3호
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• pp.585-590
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• 2012

관상동맥 중재술은 관상동맥 조영술과 동시에 치료를 시행하는 방법으로 심도관 검사의 핵심으로 자리잡았다. 관상동맥중재술 시에는 혈관의 협착지점에 스텐트를 삽입하여야 하기 때문에 혈관의 손상이나 파열에 주의하여야 한다. 이에 시술자는 혈관의 손상이나 파열의 문제를 해결하기 위해 혈관의 경로를 정확하게 인식하여야 한다. 하지만 영상의 화질에 따른 문제들로 인하여 혈관의 경로추출에 오류를 범할 수 있다. 따라서 본 논문에서는 영상의 화질에 영향을 미치는 영상잡음에 대한 성능평가를 위하여 전처리 과정으로 미디언 필터링을 실시하였고 비교 실험을 위해 소벨 에지 추출 기법을 이용하여 퍼지 에지 추출 기법의 성능을 실험하였다. 그 결과 미디언 필터링을 적용한 퍼지 에지추출 기법의 영상이 잡음 제거와 신호의 검출 성능이 우수하게 나타났다.

• 척추신경추나의학회지
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• 제7권1호
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• pp.103-112
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• 2012

Objectives : This study was performed to report the effect of oriental medical treatments on the 4 patients with lateral epicondylitis of the elbow. Methods : The 4 patients were treated by Bee Venom acupuncture, Dong-Qi acupuncture, acupuncture on tender points of the origin of the extensor carpi radialis and taping on the extensor carpi radialis. The state of patients was measured by visual analog scale(VAS), elbow range of motion(ROM) and patient's subjective symptom grade(PSSG). Results : After mean 9.5 times of treatments, the recovery of elbow ROM was measured and significant pain relief was seen as the average of VAS changed from 10 to 1.25 and average of PSSG changed from 2.75 to 0.5 grade. Conclusions : These results suggest that oriental medical treatments including Bee Venom acupuncture, Dong-Qi acupuncture, acupuncture, taping are effective to improve the lateral epicondylitis of the elbow.

• 척추신경추나의학회지
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• 제7권1호
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• pp.35-47
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• 2012

Sway-back 자세를 가진 환자 3례에 전방락킹, 후방락킹 운동 및 MET를 이용하여 치료한 결과 Whole spine X-ray(lateral)상의 척추만곡각도 및 NRS score의 호전을 확인하였다. 이에 저자는 본 증례를 보고하는 바이다.

• Radiation Oncology Journal
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• 제12권1호
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• pp.99-107
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• 1994

Among the 63 patients with histopathologically proven primary squamous cell anal cancer who were managed in Presbyterian Medical Center and Yonsei University Cancer from Jan. 1971 to Dec. 1991, 34 patients, who were managed with surgery alone(abdominoperineal resection) or post-operative radiotherapy and concurrent chemoradiotherapy were analysed. With mean follow up time of 81.3 months, 30 Patients(88$ \% $) were followed up from 17 to 243 months. In methods, 10 patients were treated with surgery alone. 9 Patients were treated with combined surgery and postoperative radiotherapy(50$\∼$60 Gy in 28$\∼$30 fractions). 15 patients were treated with concurrent chemoradiotherapy. Chemotherapy (Mitomycin C 15 mg/squ, bolus injection day 1;5-FU, 750 mg/squ, 24hr infusion, day 1 to 5) and radiotherapy started the same day. A dose of 30 Gy was given to the tumor and to the pelvis including inguinal nodes, in 15 fractions. After 2 weeks a boost of radiotherapy(20 Gy) to the ano-perineal area and second cycle of chemotherapy completed the treatment. The overall 5-year survival rate was 56.2$ \% $. Concurrent chemoradiotherapy group was 70$ \% $ and surgery alone group was 16.7$ \% $. According to the cox proportional harzard model, there was significant difference between survival with concurrent chemoradiotherapy and surgery alone(p=0.0129), but post-operative radiotherapy was 64.8$ \% $, which was not stastically significant(p=0.1412). In concurrent chemoradiotherapy group, the anal funtion Preservation rate was 87$ \% $ and the severe complication rate(grade 3 stenosis and incontinence) was 13.3$ \% $. In conclusion, we conclude that the concurrent chemoradiotherapy may be effective treatment modality in patients with anal cancer.

• Journal of Chest Surgery
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• 제43권1호
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• pp.58-62
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• 2010

심실 중격 결손과 폐동맥 협착을 가지고 있는 대혈관 전위 환자의 수술적 치료방법으로 Rastelli 수술법이 보편화되어 왔으나, 추적 관찰 중에 심장외 도관의 폐쇄, 좌심실 유출로의 폐쇄, 부정맥이 높은 확률로 발생하는 등의 장기 성적이 만족스럽지 못하였다. 이와 같은 문제점을 해결하기 위해 본원에서 2003년과 2006년에 심실 중격 결손과 폐동맥 협착을 가지고 있는 대혈관 전위 환자 2명을 반회전 동맥간 회전술 및 Lecompte 술식을 이용하여 수술하였고, 추적 관찰을 통해 양심실 유출로의 중기 변화에 대한 경험을 보고한다.