In order to evaluate the significance of thyrotropin-binding inhibiting immunoglobulin (TBII) in the patients with autoimmune thyroid diseases, the authors investigated 402 cases of Graves' disease and 230 cases of Hashimoto's thyroiditis comparing 30 cases of normal healthy adult at Kyung Pook University Hospital from February 1993 to August 1994. The TBII was tested by radioimmunoassay and assesed on the dynamic change with the disease course, thyroid functional parameters, and other thyroid autoantibodies : antithyroglobulin antibody (ATAb) and antimicrosomal antibody (AMAb) including thyroglobulin. The serum level of TBII was $40.82{\pm}21.651(mean{\pm}SD)%$ in hyperthyroid Graves' disease and $8.89{\pm}14.522%$ in Hashimoto's thyroiditis and both were significant different from normal control of which was $3.21{\pm}2.571%$. The frequency of abnormally increased TBII level was 92.2% in hyperthyroid Graves' disease, 46.7% in euthyroid Graves' disease or remission state of hyperthyroidism, and 23.9% in Hashimoto's thyroiditis. The serum levels of increased TBII in Graves' disease were positively correlated with RAIU, serum T3, T4, and FT4, but negatively correlated with serum TSH(each P<0.001). The TBII in Graves' disease had significant positive correlation with serum thyroglobulin and AMAb, but no significant correlation with ATAb. In the Hashimoto's thyroiditis, the serum levels of TBII were positively correlated with RAIU, serum T3, TSH and AMAb, but not significantly correlated with serum T4, FT4, thyroglobulin and ATAb. Therefore serum level of TBII seemed to be a useful mean of assessing the degree of hyperthyroidism in Graves' disease and correlated well with thyroidal stimulation. The serum level of TBII in Hashimoto's thyroiditis is meaningful for the degree of both functional abnormality reflecting either hyperfunction or hypofunction and the immune logic abnormality.
Journal of the Korean Society of Fisheries and Ocean Technology
/
v.33
no.4
/
pp.275-284
/
1997
This experiment was carried out to measure the sinking depth of each buoy, the change in the net shape of the net, and the tension of sand bag line according to the R (from bag net to the fish court) and L (from fish court to the bag net) current directions and their velocity by the model experiment. The model net was one-fiftieth of the real net, and its size was determined after considering the Tauti’s Similarity Law and the dimension of the experimental tank. 1. The changes of the net shape were as follows : In the current R, the end net of fish court moved 20mm down the lowerward tide and 10mm upper part. So the whole model net moved up at 0.2m/sec. The shape of the net showed an almost linear state from bag net to the fish court at 0.6m/sec. In the current L, the door net moved 242mm down the lowerward tide and 18mm upper part. So the whole model net moved up at 0.2m/sec. The net shape showed an almost linear state from the fish court to the bag net at 0.5m/sec. 2. The sinking depths of each buoy were as follows: In the current R, the head buoy started sinking at 0.2m/sec and sank 20mm, 99mm at 0.3m/sec and 0.6m/sec, respectively. The end buoy didn't sink from 0m/sec to 0.6m/sec but showed a slight quake. In the current L, the end buoy started sinking at 0.1m/sec, and sank 5mm and 108mm at 0.2m/sec and 0.6m/sec, respectively. The whole model net sank at 0.5m/sec except the head buoy. 3. The changes of the sand bag line tension were as follows: In the current R, the tension affected by the sand bag line of the head buoy showed 273.51g at 0.1m/sec increased to 1298.40g at 0.6m/sec. In the current L, the tension affected by the sand bag line of the end buoy on one side showed 137.08g at 0.1m/sec increased to 646.00g at 0.6m/sec. The changes in the sand bag line tension were concentrated on the sand bag line of the upperward tide with increasing velocity at the R and L current directions. However, no significant increase in tension was observed in the other sand bag lines.
The Journal of the Korean Society for Microbiology
/
v.18
no.1
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pp.73-85
/
1983
The advantages of the enzyme-linked immunosorbent assay(ELISA) are its sensitivity and its simplicity in detecting IgM and IgG antibodies. For applying the ELISA to the diagnosis of typhoid fever, first of all, experiments were performed to determine which concentration of killed whole cell antigens and lipopolysaccharide(LPS) antigens of S. typhi(0.901 w) were optimally coated to the wells of the polystyrene and polyvinylchloride microplate, using the hyperimmune sera from rabbits against S. typhi. By using both kinds of antigens of S. typhi adsorbed to the ELISA microplate, the changing patterns of IgG and IgM antibodies in the sera from rabbits responding to the killed whole cell antigens of S. typhi(0901 w) during the prolonged immunization were serially traced by the ELISA. At the same time, the level of antibodies against S. typhi in sera fron patients with typhoid fever and from normal healthy persons were measured by the ELISA employing the killed whole cell antigens and LPS antigens as the coating antigens. The results obtained were summerized as follow: 1. The optimal concentration of the killed whole cell antigens, which were more easily adsorbed to the polystyrene plate than the polyvinylchloride plate, was $10^8cells/ml$ of carbonate buffer(pH. 9.6) on the wells of the polystyrene plate when treated at $37^{\circ}C$ for 4 hours. On the other hand, the optimal concentration of lipopolysaccharide antigens, which were adsorbed only to the polyvinylchloride plate, was $100{\mu}g/ml$ of carbonate buffer(pH. 9.6) on the wells of the polyvinylchloride plate when treated at $37^{\circ}C$ for 4 hours. 2. IgM antibody response were dominating in rabbits responding to the killed whole cell antigens of S. typhi(0.901 w), and were more specific to the LPS antigens than to the killed whole cell antigens in the ELISA. Good correlations were made between the IgM titers by the ELISA and the aggglutinating titers of sera from the immunized rabbits. 3. Both IgG and IgM agglutination titers by the ELISA in sera from most of patients with typhoid fever were above 1:320 but those in sera from most of normal, healthy persons were below 1:80. 4. There were close correlations between the antibody titers by the ELISA and the agglutinating titers to the killed whole cell antigens in the tested human sera, IgM titers being more correlated with the agglutinating titers than IgG titers. But a little correlations were made between the antibody titers by the ELISA and the agglutinating titers to the LPS antigens. 5. IgM titers in the tested human sera were similar to IgG titers detected by the ELISA employing the killd whole cells antigens and the LPS antigens. 6. Good correlations were made between the antibody titers demonstrated by the ELISA performed on the killed whole cell antigens and the LPS antigens as the different, coating antigens on the ELISA microplates.
Recently many studies have reported that total and bioavailable androgens reduced in male and female athletes and that physical exercise reduces the body weight and increases the reproductive abnormalities such as oligomenorrhea, anovulation, inadequate luteal phase, and delayed puberty in women by the inhibition of the hypothalamic-pituitary-gonadal (HPG) axis . In addition, high mileage endurance 겨nning, psychological stress, and military endurance training in men also reduce the secretion of reproductive hormones. To investigate the efffcts of physical endurance exercise on the secretion of reproductive hormones in men, androgenic hormones from adrenal glands and testis were measured in serum by the conventional radioimmunoassays after long-term (more than3 months), short-term (1 week), and acute (1${sim}$2 hours) physical exercises. Androgenic hormones from adrenal glands and testis such as total testosterone (TT), free testosterone (fT), dehydroepiandrosterone (DHEA), and androstenedione (A) decreased after thesestrenuous endurance trainings, whereas ACTH, cortisol, and dehydroepiandrosterone sulfetes (DHEAS) increased. Conadotropins (LH and FSH) were not idluenced by the physical exercises. Based upon the present results, we assume that the decrease in adrenal and testicular androgens by physical endurance exercises might be associated with the reproductive abnormalities in athletes by unknown factor(s) in addition to the HPG axis disturbance.
Korean Journal of Agricultural and Forest Meteorology
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v.21
no.4
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pp.238-249
/
2019
The evapotranspiration is estimated based on weather factors such as temperature, wind speed and humidity, and the Hargreaves equation is a simple equation for calculating evapotranspiration using temperature data. However, the Hargreaves equation tends to be underestimated in areas with wind speeds above 3 m s-1 and overestimated in areas with high relative humidity. The study was conducted to determine Hargreaves equation coefficient in 82 regions in Korea by comparing evapotranspiration determined by modified Hargreaves equation and the Penman-Monteith equation for the time period of 2008~2018. The modified Hargreaves coefficients for 50 inland areas were estimated to be 0.00173~0.00232(average 0.00196), which is similar to or lower than the default value 0.0023. On the other hand, there are 32 coastal areas, and the modified coefficients ranged from 0.00185 to 0.00303(average 0.00234). The east coastal area was estimated to be similar to or higher than the default value, while the west and south coastal areas showed large deviations by area. As results of estimating the evapotranspiration by the modified Hargreaves coefficient, root mean square error(RMSE) is reduced from 0.634~1.394(average 0.857) to 0.466~1.328(average 0.701), and Nash-Sutcliffe Coefficient(NSC) increased from -0.159~0.837(average 0.647) to -0.053~0.910(average 0.755) compared with original Hargreaves equation. Therefore, we confirmed that the Hargreaves equation can be overestimated or underestimated compared to the Penman-Monteith equation, and expected that it will be able to calculate the high accuracy evapotranspiration using the modified Hargreaves equation. This study will contribute to water resources planning, irrigation schedule, and environmental management.
This study was conducted to provide strategies for the reduction of plate waste and prevention of plate waste reuse in foodservice operations. To achieve these goals, we surveyed the entrepreneurs of foodservice operations, professionals in the field of foodservice management and food safety, and public officials working for food safety enforcement about their perceptions and strategies on plate waste management. The professionals' survey indicated that definition of plate waste needed to be clear for understanding. Also Korean food culture insisting on abundance and variety table settings, foodservice owners' demands for cost reduction, and foodservice workers' insufficient safety perceptions were indicated to bring forth the practice to reuse plate waste. The effective ways to control plate waste management were systematic educational supports for Korean food culture upgrade among consumers and improvements of safety perceptions among owners, as well as workers. Also small portion size was needed to reduce plate waste.
Journal of the Korean Society of Fisheries and Ocean Technology
/
v.20
no.1
/
pp.49-59
/
1984
Optimizing investigation of characteristics of underwater welding by a gravity type arc welding process was experimentally carried out by using six types of domestic coated welding electrodes for welding of domestic marine structural steel plates (KR Grade A-1, SWS41A, SWS41B,) in order to develop the underwater welding techniques in practical use. Main results obtained are summarized as follows: 1. The absorption speed of the coating of domestic coated lime titania type welding-electrode became constant at about 60 minutes in water and it was about 0.18%/min during initial 8 minutes of absorption time. 2. Thus, the immediate welding electrode could be used in underwater welding for such a short time in comparison with the joint strength of in-atmosphere-and on-water-welding by dry-, wet-or immediate-welding-electrode. 3. By bead appearance and X-ray inspection, ilmenite, limetitania and high titanium oxide types of electrodes were found better for underwater-welding of 10 mm KR Grade A-1 steel plates, while proper welding angle, current and electrode diameter were 6$0^{\circ}C$, above 160A and 4mm respectively under 28cm/min of welding speed. 4. The weld metal tensile strength or proof stress of underwater-welded-joints has a quadratic relationship with the heat input, and the optimal heat input zone is about 13 to 15KJ/cm for 10mm SWS41A steel plates, resulting from consideration upon both joint efficiency of above-100% and recovery of impact strength and strain. Meanwhile, the optimal heat input zone resulting from tension-tension fatigue limit above the base metal's of SWS41A plates is 16 to 19KJ/cm. Reliability of all the empirical equations reveals 95% confidence level. 6. The microstructure of the underwater welds of SES41A welded in such a zone has no weld defects such as hydrogen brittleness with supreme high hardness, since the HAZ-bond boundary area adjacent to both surface and base metal has only Hv400 max with the microstructure of fine martensite, bainite, pearlite and small amount of ferrite.
The upcoming century is a knowledge based society which did not exist before which requires creative ability to solve problems. Therefore, it is necessary to Provide a creative program of problem solution in order to match this global trend The creativity of problem solution means the ability to solve a problem using previous ideas in an advanced way or develop new ideas. Creative education is especially important for infants. Because the young mind is where fresh ideas preside and can frame-work the early stage of life like a blank sheet of paper. The Infant-Early Child Creative Development Institute. as an adhesive institute at Yeungjin College, develops various programs that integrate methods which match current trend in this era and also start the Creative Promotion Test with 2,000 Families for the expansion of creative education from the baseline as an alternative method. The infants tested in the creative test will find ways of problem solution through animation beam projects for their given situation and also discuss the problems with their family members. Through these processes the infant and family members will complete the creative structures to solve the problems using limited materials given by the institute, and the final product will be evaluated as objective results. The final evaluation of the test will also be considered the teamwork of family cooperation and the attitudes of participants as well as the product of problem solution. The criterion of the evaluation is to be considered both a creative way of thinking and creative attitudes. Because the score counts were conducted manually it delayed the selection of awarded students who took the test. Also, we found that some parents have difficulty in accessing information to find the score through homepage from the computer. this Problem might be corrected in the future plan. Like Freud's saying, if human character and exploring attitudes during the early stage of a child, a person's creativity is composed their infant period as their basic foundation. Therefore, the family wh first environment the infant encounters will be treated as a prima when making basic structure. From this viewpoint, this creative test work as a festival of creativity fare with 2,000 families.
The East China Sea is an important region as nursery and spawning grounds for pelagic fishes such as jack mackerel, common mackerel etc. , and thus constitutes a major fishing area for purse-seine fishery. The environment surrounding in this region is under the influence of the Yellow Sea Cold Water, China Coastal Water and Kuroshio Current. The purpose of this study was to clarify the effects of oceanographic conditions and thermal fronts on the formation of the fishing grounds for the mackerels in the East China Sea. Through the analyses of fisheries statistics during 1968-1976 and temperature data, the following facts are found: 1) Approximately $70\%$ of the total mackerel(common) catches appeared to be come from the Tsushima Current region which includes Sakai coast of the Japan Sea, eastern Tsushima and Shirase Island, and Jeju Island of Korea. This area covers only about $8\%$ of the East China Sea. 2) Main fishing grounds for the jack mackerel are also centered around the area of southwestern Goto, Shirase and eastern Tsushima Island where the catches accounted for about $54\%$ of the total jack mackerel catches. 3) Fluctuations in annual catches are relatively small in the Tsushima Current region, compared to other regions such as Yellow Sea, southwestern coast of Kyushu and mid-western part of the East China Sea, where the fisheries yields varied considerably due to unstable fishing conditions. 4) It appears that the fishing grounds for the jack mackerel are mainly distributed along the warmer region ($15-20^{\circ}C$) of the thermal front, and those for the common mackerel are in somewhat colder region ($13-16^{\circ}C$) in the Tsushima Current.
Stability of the braced earth wall in the composite ground, which is composed of the jointed base rocks and the soil strata depends on the earth pressure acting on it. In most cases, the earth pressure is calculated by the empirical method, in which base rocks are considered as a soil strata with the shear strength parameters of base rocks. In this case the effect of the joint dips of the jointed base rocks is ignored. Therefore, the calculated earth pressure is smaller than the actual earth pressure. In this study, the magnitude and the distribution of the earth pressure acting on the braced wall in the composite ground depending on the joint dips of the base rocks and the ratio of soil strata and base rocks were experimentally studied. Two dimensional large-scale model tests were conducted in a large scale test facility (height 3.0 m, length 3.0 m and width 0.5 m) by installing 10 supports in a scale of 1/14.5. The test ground was presumed with the base rock ratio of the composite ground of 65%:35% and 50%:50% and with the joint dips for each base rock layer, $0^{\circ}$, $30^{\circ}$, $45^{\circ}$ and $60^{\circ}$, respectively. And then finite element analyses were performed in the same condition. As results, the earth pressure on the braced wall increased as the base rock layer's joint dips became larger. And earth pressure at the rock layer increased as the rock rate became larger. The largest earth pressure was measured when the base rock rate was 50% (R50) and the rock layer's joint dips was $60^{\circ}$. Based on these results, a formular for the calculation of the earth pressure in the composite ground could be suggested. Distribution of earth pressure was idealized in a quadrangular form, in which the magnitude and the position of peak earth pressure depended on the rock ratio and the joint dips.
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