• Journal of the Korean Society of Food Science and Nutrition
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• v.18 no.1
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• pp.93-100
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• 1989

The effect of each azalea(Rhodoendron mucronulatum) pollen extract on phase I enzyme(aniline hydroxylase)was studied in this experiment. Serum aminotransferases were not changed in mice injected each azalea pollen extract, respectively compared to control group. The hepatic micros mal aniline hydroxylase activities in the presence of each azalea pollen extract were not affected in vitro. After treatment with azalea pollen water extract, hepatic microsomal aniline hydroxylase activity was increased with dose-dependent manner as compared to control group. The increment of hepatic microsmal aniline hydroxylase activity was more powerful by the treatment of water extract. As mice received aniline after pollen butanol and water extract-pretreatment once a day for 5 days, the blood and liver levels of aniline were decreased significantly.

• Journal of Ginseng Research
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• v.32 no.4
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• pp.382-389
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• 2008

To achieve a better understanding of protective effects of water extracts of Panax ginseng against TCDD-induced toxicities, we monitored physiological and clinical changes in rat for 4 weeks after administrations of each Panax Ginseng extract or TCDD, and co-administration of the two materials. For this study, 120 male Sprague-Dawley (SD) rats weighing 190-210 g each (8 weeks old) were divided into four groups: TCDD-administered, co-administered group with TCDD and ginseng extract, ginseng extract-administered, and control group. The TCDD-administered group received single dose of TCDD in a corn oil vehicle ($25\;{\mu}g/kg$ body weight) by intraperitoneal administration on Day 1. The Panax ginseng extracts-administered group received intraperitoneally 100 mg/kg body weight every other day for one month. For the co-administered group with TCDD and ginseng extracts, Panax ginseng extracts were intraperitoneally administered to rats at 100 mg/kg body weight every other day for one month after a single intraperitoneal dose of $25\;{\mu}g$ of TCDD/kg body weight on Day 1. Panax ginseng extracts attenuated the mortality induced by TCDD administration. The extracts also slightly attenuated the TCDD-induced body weight loss. Administration of TCDD alone increased liver weight at 2, 5, and 16 days after administration of TCDD. Administration of Panax ginseng extracts rather decreased liver weight through whole the experimental period, but which was statistically insignificant. Administration of TCDD alone at $25\;{\mu}g/kg$ body weight increased both serum enzyme activities of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) at 32 days, indicating that liver damage occurred maximally at that time. Ginseng extract administration caused insignificant changes in serum ALT, but gradually decreased in AST as the exposure time increased. Coadministration of TCDD and ginseng extracts caused serum AST activity to significant recovery to normal value at 16 days and 32 days after exposure to TCDD. The extracts also significantly decreased the TCDD-induced ALT activity after 16 days of TCDD administration. These results suggest that Panax ginseng extracts may possess a protective effect against TCDD-induced toxicities including hepatotoxicity in rats.

• Journal of the Korean Society of Food Science and Nutrition
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• v.25 no.2
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• pp.188-192
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• 1996

닭을 실험모델로 Pinus strobus 잎의 메탄올 추출물 투여에 의한 콜레스테롤 저하효과를 검토하였다. 닭에 메탄올 추출물 100mg을 50% 에탄올용액 0.5ml에 녹여 2주간 매일 경구투여하였을 때, 유의한 추출물의 투여효과는 관찰되지 않았다. 두 번째 실험에서는 메탄올 추출물의 투여량을 하루 200, 350 또는 50mg으로 달리하여 2주간 경구투여하였다. 2주 후 하루 200mg을 투여한 군은 다른 군에 비하여 유의하게 낮은 혈청 콜레스테롤 농도를 나타내었으나, 투여량의 증가에 의한 부가적인 저하효과는 관찰되지 않았다. 메탄올 추출물은 여러 가지 추출용매로 재분획되었다. 그 중에서 에틸아세테이트 추출물(100mg/일)은 혈청 콜레스테롤 농도를 20%까지 감소시켰다. 이러한 결과로부터 Pinus strobus 잎의 메탄올 추출물의 투여는 닭에서 혈청 콜레스테롤 농도 저하의 개선효과가 있음이 시사된다.

• Proceedings of the Korean Information Science Society Conference
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• 2002.10d
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• pp.364-366
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• 2002

본 논문에서는 텍스트 형태로 구성된 특정 생물에 대한 문헌 데이터에서 해당 생물의 주요 단백질간의 이진(binary) 관계를 추출하여 이들을 특징별로 계층적으로 군집화 함으로써 특정 현상을 나타내는 단백질간의 주요 관계를 추출하는 방법을 제시한다. 텍스트 데이터에서 단백질간의 이진관계는 기본적인 데이터마이닝 기법을 사용하여 연관규칙(association rule)의 형태로 추출하게 된다. 본 논문에서는 실험을 위해 PUBMED에서 추출한 Yeast의 주요 단백질간의 관계를 포함하고 있는 논문 데이터인 MEDLINE Abstract와 몇몇 공개 데이터베이스를 사용하였다. 실험 결과 SH3와 같이 기존에 알려진 단백질간의 단일 관계를 추출하는 것 이외에 이러한 관계들을 이용하여 클러스터링을 행한 결과 공통 현상에 작용하는 주요 단백질간의 관계들이 서로 군집화 됨을 확인 할 수 있었다. 또한 단순 이진관계가 아닌 클러스터링을 이용한 보다 상위 단계에서 단순 규칙들 간의 관계를 살펴봄으로써 단백질간의 이진관계를 추출하기 위한 데이터로 사용한 문헌 데이터에 나타나 있지 않은 1차 이상의 관계를 고찰 해 볼 수 있었다. 논문에서는 규칙 추출의 전체 과정과 함께 사용된 추출 시스템의 각 부와 데이터에 대한 설명을 다룬다.

• Korean Journal of Plant Resources
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• v.24 no.1
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• pp.10-16
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• 2011

We investigated the antimicrobial activity of ether and ethylacetate fractions from Artemisia capillaris and Artemisia iwayomogi used as Injin. The antimicrobial activity of the ethylacetate fractions from Artemisia capillaris and Artemisia iwayomogi for tested microbes were stronger than those of ether fractions of the two Artemisia plants. The antimicrobial activity of fractions of Artemisia iwayomogi was higher than that of fractions of Artemisia capillaris for the tested microbes. The extracts of young shoots and leaves showed stronger antimicrobial activity than those of young leaves. The range of minimum inhibitory concentrations(MICs) of ethylacetate fractions from the part of Artemisia capillaris and Artemisia iwayomogi were 0.25~2.0 mg/ml. The MICs of ether fractions were showed higher concentration than those of ethylacetate fractions. The fractions of Artemisia iwayomogi showed lower MICs than fractions of Artemisia capillaris. The highest total polyphenol content was found in young shoots and leaves of A. capillaris. The young shoots and leaves of the two kinds of Artemisia plants showed higher content of total polyphenol.

• Annual Conference on Human and Language Technology
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• 2021.10a
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• pp.482-485
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• 2021

최근 지식 그래프를 확장하기 위해 많은 연구가 진행되고 있다. 지식 그래프를 확장하기 위해서는 relation을 기준으로 entity의 방향성을 고려하는 것이 매우 중요하다. 지식 그래프를 확장하기 위한 대표적인 연구인 관계 추출은 문장과 2개의 entity가 주어졌을 때 relation을 예측한다. 최근 사전학습 언어모델을 적용하여 관계 추출에서 높은 성능을 보이고 있지만, entity에 대한 방향성을 고려하여 relation을 예측하는지 알 수 없다. 본 논문에서는 관계 추출에서 entity의 방향성을 고려하여 relation을 예측하는지 실험하기 위해 문장 수준의 Adversarial Attack과 단어 수준의 Sequence Labeling을 적용하였다. 또한 관계 추출에서 문장에 대한 이해를 높이기 위해 BERT모델을 적용하여 실험을 진행하였다. 실험 결과 관계 추출에서 entity에 대한 방향성을 고려하지 않음을 확인하였다.

• Journal of Mushroom
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• v.17 no.3
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• pp.152-161
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• 2019

Phallus impudicus var. impudicus L. is an edible mushroom that has long been used as folk medicine in China. The aim of this study was to evaluate the antioxidant, anti-cholinesterase, and inflammation inhibitory activities of a methanol extract of fruiting bodies of P. impudicus var. impudicus L. The extract exhibited good 1,1-diphenyl-2-picrylhydrazyl scavenging activity, excellent ferrous ion chelating activity, and moderate hydroxyl radical scavenging activity compared with BHT at 2.0 mg/ml. However, the reducing power of the extract was significantly lower than that the BHT positive control. Although the inhibitory activities of methanol extract on acetylcholinesterase and butyryl cholinesterase were significantly lower than the galanthamine positive control at the concentration tested, the inhibition of acetylcholinesterase and butyryl cholinesterase was 52.83% and 55.17%, respectively, at 1.0 mg/ml. The methanol extract also demonstrated excellent inhibition of inflammation-related activities, such as production of nitric oxide in lipopolysaccharide-induced RAW 264.7 macrophage cells and acute edema induced by administration of carrageenan on the hind paw of rats. The collective results suggest that the fruiting body of P. impudicus var. impudicus L. might be a good source of antioxidant, anti-cholinesterase, and anti-inflammation compounds.

• Journal of Food Hygiene and Safety
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• v.34 no.4
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• pp.396-403
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• 2019

Ion-exchange chromatography and ultrafiltration were used to extract anserine from salmon (Oncorhynchus keta). The salmon anserine showed DPPH radical scavenging activity in the range of 7.30% to 31.05% in a dose-dependent manner. This reducing power of salmon anserine also increased as the concentration increased. Metal chelate activity, superoxide dismutase - like activity, and thiobarbituric acid reactive substances assay showed similar results. The anserine also suppressed the increment of the peroxide value and linoleic acid during storage periods. These results suggest that salmon anserine might be useful as a natural antioxidant in various foodstuffs.

• The Journal of the Korea Contents Association
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• v.2 no.1
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• pp.59-67
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• 2002

This study pre-processed the characters, performed the feature extraction for the beauty evaluation, and then defined the similarity function. It suggested the definition of the similarity function, and the extraction of the features of character elements. it experimented how much the various input character patterns were similar with the standard character patterns, found their results were almost similar with the expected ones and the results of beauty evaluation on general people through the questionaire with the results of the methods suggested here.

• Proceedings of the Korea Multimedia Society Conference
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• 2002.11b
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• pp.254-258
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• 2002

멀티미디어의 내용 기반 검색을 위한 표준인 MPEG-7은 컨텐츠의 비주얼 내용 정보를 표현하기 위해 Part3에서 비주얼 기술자를 정의하고 있다. MPEG-7 비주얼 컬러 기술자에 의해 정의된 컨텐츠의 컬러 정보를 추출하기 위해서는 주파수 영역 정보를 공간 영역 정보로 변환해야 한다. 이때 변환 과정에서 수행되는 IDCT(Inverse DCT)의 연산 속도는 특징 추출 시간을 증가시키는 원인이 된다. 본 논문에서는 IDCT의 연산 시간을 최소화하는 방법으로 DCT 계수 영역에서 컬러 특징 정보를 빠르게 추출하는 방법에 대해 제안하였다. 제안한 방법에 대해 MPEG-7 실험 모듈과 공인 데이터 베이스를 이용하여 실험을 수행하였고 실험 결과, 검색 율이 평균 5% 감소한 반면 추출 시간은 평균 80% 향상되었다.