• Radiation Oncology Journal
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• v.10 no.1
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• pp.95-100
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• 1992

Since LINAC-based stereotactic radiosurgery uses multiple noncoplanar arcs, three-dimensional dose evaluation and many beam parameters, a lengthy computation time is required to optimize even the simplest case by a trial and error. The basic approach presented in this paper is to show promising methods using an experimental optimization and an analytic optimization The purpose of this paper is not to describe the detailed methods, but introduce briefly, proceeding research done currently or in near future. A more detailed description will be shown in ongoing published papers. Experimental optimization is based on two approaches. One is shaping the target volumes through the use of multiple isocenters determined from dose experience and testing. The other method is conformal therapy using a beam's eye view technique and field shaping. The analytic approach is to adapt computer-aided design optimization in finding optimum irradiation parameters automatically.

• Analytical Science and Technology
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• v.6 no.3
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• pp.313-318
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• 1993

The rose petal tissue biosensor has been constructed by immobilizing New carina rose tissue. Optimum conditions for the determination of urea were investigated using this sensor. Selectivity and life time of this sensor were also obtained. As a result, the biosensor showed the optimum response characteristics in 0.20M phosphate buffer solution at pH 8.0, $37^{\circ}C$ and 50mg of tissue amounts. This sensor was linear from $9.0{\times}10^{-5}$ to $4.0{\times}10^{-3}M$ urea with a slope of 42mV/decade. The limit of detection and response time are $7.0{\times}10^{-5}M$ and 17~19 min.

• Food Industry And Nutrition
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• v.8 no.3
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• pp.45-51
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• 2003

본 연구는 생물공학적인 방법을 도입하여 폐기되는 신선초박에 H. erinaceum의 균사체를 발효시킨 배양생성물을 이용하여 기능성 건강 음료 개발을 검토 하고자 하였다. 1. 종균제조공정개발 : 기본 배지의 선발에서 Hericium erinaceum의 균사 생육에 적합한 배지를 선발하기 위하여 10여종의 고체배지를 사용하여 균사 생육 및 밀도를 조사한 결과는 YMPG 배지에서 59.8mm/14days로 균사 생육이 가장 우수한 것으로 나타났고, 최적 온도는 20-$25^{\circ}C$ 범위에 가장 생육이 좋았으며, 배지의 pH를 조절하여 균사생육을 조사한 결과, pH는 5.5, 접종비는 전배양액 9%(v/v), 배양에 적합한 배지액량은 50mL, 최적교반속도는 120rpm이었다. 이러한 최적 조건 하에서 배양 경시 변화를 살펴 본 결과 당은 거의 일정한 속도로 감소하는 반면에 건조균체량은 배양 8일째까지 증가하다가 더 이상 변화가 없었다. 2. 발효공정개발: 수분함량이 200%(v/v)에서, pH5에서의 생육속도는 90mm/30 days, $25^{\circ}C$에서의 균사생육속도는 89mm/30days로 각각 H. erinaceum균사의 생육이 가장 우수한 결과를 얻었다 3.추출공정 및 시제품 제조: 녹즙을 생산한 후 폐기되는 신선초박에 액체 종균을 접종하여 ,40일 동안 배양시켜 생육 상태가 우수한 배양생성물만을 선별하여, 열수추출방법으로 10$0^{\circ}C$, 10시간 추출한 것을 음료제조의 원료로 하고, 음료의 기호성을 향상시키기 위해 유기산 및 한방추출물을 첨가하는 균사체음료의 조성비를 얻었다.

• Microbiology and Biotechnology Letters
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• v.18 no.4
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• pp.417-422
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• 1990

For optimal production of fructosyl transferase in AureobasidiumpuZZulane C-23, the effect of fermentation conditions for cell growth and fructosyl transferase production were investigated. Sucrose was excellent carbon source. Sucrose concentration for the optimum production of fructosyl transferase was 35%. Enzyme productivity was significantly increased by addition of ammonium oxalate and yeast extract. A time course study for the enzyme production by Aureobasidium pullutans C-23 was carried out. At 2 days incubation, the production of intracellular enzyme was maximum. The extracellular enzyme production was found to be increased up to 6 days.

• Journal of Korean Society of Transportation
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• v.23 no.6 s.84
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• pp.91-102
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• 2005

When it comes to the process of information storage, people are likely to organize individual information into the forms of groups rather than independent attributes, and put them together in their brains. Likewise, in case of finding the shortest path, this study suggests that a Hierarchical Road Network(HRN) model should be selected to browse the most desirable route, since the HRN model takes the process mentioned above into account. Moreover, most of drivers make a decision to select a route from origin to destination by road hierarchy. It says that the drivers feel difference between the link travel tine which was measured by driving and the theoretical link travel time. There is a different solution which has predicted the link travel time to solve this problem. By using this solution, the link travel time is predicted based on link conditions from time to time. The predicated link travel time is used to search the shortest path. Stochastic Process model uses the historical patterns of travel time conditions on links. The HRN model has compared favorably with the conventional shortest path finding model in tern of calculated speeds. Even more, the result of the shortest path using the HRN model has more similar to the survey results which was conducted to the taxi drivers. Taxi drivers have a strong knowledge of road conditions on the road networks and they are more likely to select a shortest path according to the real common sense.

• Journal of the Korean Wood Science and Technology
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• v.32 no.5
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• pp.12-19
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• 2004

This study was performed to investigate the optimum condition of protease production from submerged culture of oak mushroom (Lentinula edodes, Sanlim No. 5) and its enzymatic features. Among several combinations of media, the combination of wheat bran, corn flour, water and corn oil (WB+CF+W+ CO) yielded 84.8 U/g of maximum protease activity. This combination of ingredients, in spite of not being particularly protein-rich in comparison to the other media, allowed for good growth of the fungus and maximal protease production. Comparison of different growth medium liquids indicated that demineralized water afforded the best growth of the fungus and the highest protease activity. Acetate buffer and acidified water negatively affected The protease production peaked around 72 hr of incubation, and decreased thereafter. The molecular weights of produced protease were about 45,000 by Sephadex G-75 chromatography. The pH optimum for protease activity was 4, while maximal activity incubated at 37℃ for 1 hr was observed between pH 4~6. The optimum temperature of this protease was 55℃, and the enzyme was active over a broad temperature range (30~60℃), indicating that this protease would be suitable for a wide range of applications where. different pH and temperature are necessary, such as digestive aids, food industry, beer and tannery industries.

• Proceedings of the Korean Information Science Society Conference
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• 1998.10a
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• pp.621-623
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• 1998

본 논문에서는 공용 접근이 가능한 NTO 서버들에 대한 동기화 특성을 조사, 분석했다. 분석 주요 항목은 서버 신뢰도, 정확도 그리고 오프셋(offeset)과 전송지연의 관계이다. 이러한 분석을 위해 NTP알고리즘에서 최적 시간 동기를 위해 선택하는 값인 클럭 옻프셋, 일주지연, 분산 그리고 동기화 거리를 사용하였다. 분석 결과는동기화 거리 값의 경우 최대 700ms의 정도의 차이를 보이고, 분산의 경우 최대 300ms정도의 차이를 나타내었다. 또한 전송 지연과 오프셋은 타워 분포를 보이며, 이는 그간의 오프셋 근거의 단순 선택이 효율적이지 못할 수 있음을 보여주었다. 본 논문에서 살펴본 NTP서버 동기화 특성은 많은 NTP 서버중 최적의 조건을 찾는데 유용하게 쓰일 수 있다.

• Proceedings of the Korean Institute of Resources Recycling Conference
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• 2003.10a
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• pp.56-60
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• 2003

폐 적층세라믹콘덴서(MLCC)로부터 Ni을 회수하기 위하여 침출실험을 수행하였다. 침출용매로 $HNO_3,\;HCl\;H_2SO_4$을 사용하여 시간의 변화, 반응온도의 변화, 시료 입도와 광액농도의 변화가 Ni의 침출율에 미치는 영향과 최적 침출 조건을 조사하였다. 그 결과 HCl, $H_2SO_4$을 침출용매로 사용했을 때 Ni 침출의 최적 조건은 산농도 5M, 반응온도 $90^{\circ}C$나타났으며, $HNO_3$을 침출용매로 사용했을 때 최적 침출 조건 산농도 1M, 반응온도 $70^{\circ}C$에서 광액농도 500ml당 20g일때 Ni 침출율이 98%로 최대였다.

• Journal of Korean Society of Transportation
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• v.16 no.4
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• pp.53-64
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• 1998

본 연구의 목적은 '96년말 서울시에서 실시한 가구통행조사를 이용하여 서울시 수단선택모형을 구축하고 그 예측결과를 남산 혼잡통행료 전후저사자료와 비교하여 보다 구체적으로 그 정확성을 검증한 뒤 향후 서울시 교통수요관리 방안의 시행에 따른 수단선택변화 예측의 기본 모형으로 활용하는데 있다. 5가지의 대안모형의 분석결과 통행비용변수(승용차의 경유 주차요금포함)와 총통행시간변수(OVTT와 IVTT의 합), 승용차, 지하철, 택시상수로 구성된 모형이 최적모형으로 분석되었다. 이모형에 의한 시간가치는 9,395원, 승용차의 비용탄력성은-0.6767로서 기존 연구결과의 범위 내에 속한 것으로 나타났다. 최적모형을 이용하여 승용차통행비용이 증가한 경우를 모사분석결과 남산1,3호 터널 혼잡통행료 징수효과와 유사하게 승용차 분담율이 13% 가까이 감소한 것으로 나타나서 모형의 현실적합성도 비교적 높은 것으로 판명되었다. 향후 본 연구에서 선정된 최적수단선택모형을 통행배정모형과 결합하여 다양한 교통수요관리 방안에 따른 효과를 예측하는데 활용하면 서울과 같은 대도시의 단기적 교통관리의 수준을 한 단계 높이는데 기여할 것으로 판단된다.

• Journal of the Korean Ceramic Society
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• v.39 no.10
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• pp.1001-1006
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• 2002

Bond strength of $SrZrO_3$ resistive oxide barrier on Ag sheathed Bi(2223) tapes prepared by the sol-gel and dip-coating method was evaluated with an aid of Taguchi method and $L_18(2^1{\times}3^7)$ orthogonal arrays to determine the optimal process combination of levels of factors that best satisfy the bigger is better quality characteristic. The observed optimal condition is as follows: Sr/Zr mol ratio(0.3/0.7), amount of organic vehicle(5 wt%), drying temperature and time(160${\circ}C$, 10 min), heat treatment temperature and time(500${\circ}C$, 20 min), respectively. ANOVA analysis suggested that the influence of the factors within ${\alpha}$=0.1 was significant with a 90% confidence level.