• Title/Summary/Keyword: 촉진효과

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Facilitation of Glucose Uptake by Lupeol through the Activation of the PI3K/AKT and AMPK Dependent Pathways in 3T3-L1 Adipocytes (3T3-L1 지방세포에서 PI3K/AKT 및 AMPK 경로의 활성화를 통한 루페올의 포도당 흡수촉진 효과)

  • Lee, Hyun-Ah;Han, Ji-Sook
    • Journal of Life Science
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    • v.32 no.2
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    • pp.86-93
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    • 2022
  • Lupeol is a type of pentacyclic triterpene and has been reported to have pharmacological activities against various diseases; however, the effect of lupeol on glucose absorption has not been elucidated yet. This study aimed to investigate the effect of lupeol on glucose uptake in 3T3-L1 adipocytes. Lupeol significantly facilitated glucose uptake by translocating glucose transporter type 4 (GLUT4) to the plasma membrane of the 3T3-L1 adipocytes, which was related to activation of the phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT) and 5 'adenosine monophosphate-activated protein kinase (AMPK) pathways. In the PI3K/AKT pathway, lupeol stimulates the phosphorylation of insulin receptor substrate 1 (IRS-1), which activates PI3K. Its activation by lupeol promotes the phosphorylation of AKT, but not the atypical protein kinase C isoforms ζ and λ. Lupeol also promoted the phosphorylation of AMPK. The activation of AMPK increased the expressions of the plasma membrane GLUT4 and the intracellular glucose uptake. The increase in the glucose uptake by lupeol was suppressed by wortmannin (PI3K inhibitor) and compound C (AMPK inhibitor) in the 3T3-L1 adipocytes. The results indicate that lupeol can facilitate glucose uptake by increasing insulin sensitivity through the stimulation of the expression of plasma membrane glucose transporter type 4 via the PI3K/AKT and AMPK pathways in the 3T3-L1 adipocytes.

Effects of Some Environment-friendly Farming Materials on Growth of Pepper and Tomato Seedlings under Low Solar Radiation Conditions (저일조 조건에서 몇 가지 친환경농자재가 고추와 토마토의 유묘 생육에 미치는 영향)

  • Um, Yeong-Cheol;Seo, Tae-Cheol;Jang, Yoon-Ah;Lee, Sang-Gyu;Lee, Jun-Gu;Choi, Chang-Sun;Oh, Sang-Seok
    • Journal of Bio-Environment Control
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    • v.20 no.4
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    • pp.269-276
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    • 2011
  • The aim of this study was to evaluate the effect of 3 environment- friendly farming materials on the growth of pepper and tomato seedlings under low level of solar radiation. The pepper and tomato seedlings were separately grown on commercial substrate and non-fertilizer substrate under 30% shading condition, respectively. The microbe-, enzyme-, and amino acid-supplements were used for the foliar application to the seedlings. The application of enzyme- and amino acid-supplements significantly enhanced the growth of tomato and pepper seedlings grown on non-fertilizer substrate, while there was no significant effect on the seedlings grown on commercial substrate. The foliar application of enzyme- and amino acid-supplements reduced the days to flowering by 3 to 4 days and lowered the node order of fruit set in tomato plants grown on non-fertilizer substrate. The results showed that the enzyme- and amino acid-supplements could enhance the seedling growth and lower the node order of fruit set under limited nutritional conditions.

Effect of Low Dose γ Radiation on the Dormancy Breaking and Growth of in vitro Microtubers of Potato (Solanum tuberosum L.) Stored at Low Temperature (저선량 방사선이 저온 저장한 감자 기내 소괴경의 휴면타파와 생육에 미치는 효과)

  • Kim, Jae-Sung;Kim, Dong-Hee;Back, Myung-Hwa;Jeon, Jae-Heung;Lee, Young-Bok
    • Horticultural Science & Technology
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    • v.19 no.4
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    • pp.515-520
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    • 2001
  • To observe the stimulating effect of low dose ${\gamma}$ radiation on the dormancy breaking and growth, microtubers of two potato cultivars (Solanum tuberosum L. cv. Dejima and cv. Superior) were irradiated at the dose of 0.5-30 Gy. Though it varied with cultivars and storage duration, sprouting rate, plant growth and tuber yield were promoted by 2-8 Gy irradiation in microtuber of 'Dejima' stored at low temperature. On the other hand, in microtuber of 'Superior', sprouting rate was promoted by 2 and 4 Gy irradiation, and the growth and tuber yield by 4 Gy irradiation. These results suggest that low dose of ${\gamma}$ radiation could have stimulating effects on the dormancy breaking of microtuber and potato growth.

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The Relationship between Work-Family Facilitation and Organizational Commitment: Moderating Effect of Perceived Organizational Support (일-가정 촉진과 조직몰입 간의 관계: 조직지원인식의 조절효과)

  • Jung, Se-Hee;Son, Ah-Jin;Cha, Yunsuk
    • Journal of Digital Convergence
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    • v.11 no.12
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    • pp.229-236
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    • 2013
  • This study defined that the construct of work-family is not the opposite meaning but the construct having positive synergy effects each other. For more meaningful implications to HR partitioner in the era of smart working, Data collection was done from the manufacturing companies in Kyungsangnamdo and hierarchical regression was conducted. we investigated the relationship between work-family facilitation and organizational commitment and moderating effect of perceived organizational support between work-family facilitation and organizational commitment. Based on the result, we have proposed some implications. First, we should study more detail processes between work-family facilitation and organizational commitment not only continuous commitment but also affective and normative commitment. Second, we could know that not only work-family balance but also work-family facilitation could positively impact on organizational commitment, there when we design the job of employees, we should consider the family issues of job holder.

Growth Promotion of Tobacco Plant by 3-hydroxy-2-Butanone from Bacillus vallismortis EXTN-1

  • Ann, Mi Na;Cho, Yung Eun;Ryu, Ho Jin;Kim, Heung Tae;Park, Kyungseok
    • The Korean Journal of Pesticide Science
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    • v.17 no.4
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    • pp.388-393
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    • 2013
  • It has been well documented that Bacillus vallismortis strain EXTN-1, a beneficial rhizosphere bacterium, could enhance plant growth and induce systemic resistance to diverse pathogens in plants. However, the molecular mechanisms for how the EXTN-1 promote plant growth and induce resistances to diverse pathogens. Here, we show that 3-Hydroxy-2-butanone, a volatile organic compound (VOCs) emitted from the EXTN1, is a key factor for the bacteria-mediated beneficial effects on plant growth and defense systems. We found that the presence of volatile signals of EXTN-1 resulted in growth promotion of tobacco seedlings. The identification and analysis of EXTN-1-secreted volatile signals by solid-phase microextraction (SPME) and gas chromatography/mass spectrometry (GC/MS) indicated that a 3-hydroxy-2-butanone could provide not only the plant growth promotion, but also higher resistance against Pectobacterium carotovorum SCC1. These results suggest that a volatile compound released from EXTN-1 enhances the plant growth promotion and immunity of plants.

Effects of Low-Level Laser Irradiation on the ALP Activity and Calcified Module Formation of Rat Osteoblastic Cell (저수준레이저(GaAs 반도체)조사가 골모세포의 알칼리성 인산분해효소의 활성과 석회화결절의 형성에 미치는 영향)

  • Kyung-Hun Lee;Ki-Suk Kim
    • Journal of Oral Medicine and Pain
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    • v.21 no.2
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    • pp.279-291
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    • 1996
  • 저수준레에저요법에 대해서는 지난 10여년간 의학계 및 치과계에서 임상적으로 사용하여 좋은 결과가 있다고 많은 보고가 발표되고 있다. 특히 치근의 골결손에 관한 연구에서는 전기요법, 초음파요법, 전자장요법 등 뿐만아니라 저수준레이저를 사용하여 골절부내 Callus형성이 촉진되었음을 보고하고 새로운 치료법의 하나가 될 수 있음을 제안한 바도 있다. 본 연구에서는 칼륨비소를 다이오드로 사용한 저수준레이저조사가 골결손의 치유에 어떠한 영향을 미치는지 확인하고자 골모세포의 알칼리성 인산분해효소의 활성화와 석회화결절의 형성을 평가함으로 골모세포의 기능을 조사코저하였다. 실험은 첫째, 9개군으로 나누어 레이저 조사기간에 따른 알칼리성 인산분해효소의 활성화를 조사하였고, 둘째, 이를 근거로 9일간 계속 매일 1회 1.3 J/cm2의 레이저를 조사한 후 펄스의 종류별 차이를 비교하였으며, 세째,레이저펄스별 석회차 결절의 형성 정도를 광학현미경으로 관찰하여 비교분석하였다. 결과, 7일 계속 레이저를 조사한 경우 다른 군에 비해 서서히 ALP의 활성이 증가하였으나 유의한 차이는 없었으며. 따라서 9일동안 레이저를 계속 조사한 경우에는 전체 에너지량이 5.895 J/cm2 인 펄스13과 15가 뚜렷하게 유의한 증가를 보여주었다. 그러나 석회화결절의 형성은 전체 에너지량이 2.546 J/cm2 인 펄스11에서 가장 많았다. 결론적으로 골형성이나 알칼리성 인산분해효소의 활성을 촉진하는 데에는 적절한 레이저 조사조건이 필요하나, 알칼리성 인산분해효소의 활성을 촉진한 펄스와 석회화결절의 형성을 촉진하는 펄스가 서로 다르게 나타난 것은 골형성을 촉진하는 여러요인 들이 저수준레이저에 자극받았을 가능성이 높음을 보여준다 이러한 결과들로 보아 저수준레이저는 골모세포의 기능을 자극하여 골결손의 치유를 개선하는 데 도움될 것이라 사료된다.다. 각 백서의 양측 창상중 하나는 1,3,5,7일 마다 각 실험의 방법에 따라 레이저를 조사하고 실험동물의 다른 창상은 대조군으로서 사용하였다. 모든 창상의 면적은 실험 1,3,5,7 일째에 일정한 거리에서 사진촬영하여 면적계를 이용, 측정한 후 통계적인 의의를 조사하였다. 본 연구의 결과는 저수준레이저는 특정 조건하에서 S. aureus의 증식을 촉진하였다. 그러나 S. aureus에 감염된 창상을 저수준레이저로 조사시 치유가 촉진되었다. 중앙 조사법고 주변조사법에 의한 창상치유효과는 통계적인 의의가 보이지 않았다. 따라서 결론적으로 S. aureus 에 감염된 창상에 직접 또는 간접적이든 pulse의 종류에 관계없이 조사하는 경우 치유효과가 나타나는 것은 정사주위 조직의 LLLI 자극효과가 염증의 확산을 억제한다고 말할수 있다.4/1$0^{\circ}C$에서는 Shoa-Nan-Tsan과 Lenkwang이 가장 높았으며 백앙벼는 3 온도 조건 모두에서 활성이 낮았다. 발아소요일수와 amylase 활성과는 유의적인 정의 상관관계를 보였다., 다다조, 미국의 건답직파재배 품종 등이었으며 우리 나라 육성종들은 모두 지중에서 신장이 멈추어 제1본엽이 지중에서 추출하였으며, Scm파종심에서 불완전엽이 지면을 뚫고 나오는 품종은 Chinsura Boro뿐이었고 Nato, Labelle, Weld Pally, Italliconaverneco 등도 지면 가까이 까지 신장하였다. 6. 50% 출아일수는 제2절간장을 제외 한 모든 유아 형질의 신장도와 유의한 부의 상관을 보였는데 가장 높은 상관을 보인 것은 중배축장+제1절간장+불완전옆장이었으며, 다음이 불완전엽장이 었다. 7. 출아율은 중배축장+제1절간장+불완전엽장, 중배축장+초엽 장과 모든 파종심에서 높은 정의 상관을 보여 제1본엽의 추출 위치가 높을수록

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Strategic Study on the Plan of Promotion of the Convention Industry in Korea (우리나라 컨벤션산업의 효율적인 정보촉진방안에 관한 전략적 연구)

  • Moon, Sang-Hee
    • The Journal of Information Technology
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    • v.5 no.3
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    • pp.19-34
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    • 2002
  • The aim of this paper was to study the theoretical background of the convention industry firstly, in which will serve to seek for more efficient plan of promotion. As a result of it, it is found that the convention industry has the characteristics similar to service industry rather than manufacturing, as well as complicated, interdependent ones which are closely related to every field of industries. This paper also considers the advertising, human marketing, and public relations as measures of promoting the convention industry in order to maximize its promotion activities with the characteristics of service industry and establish the plan of promoting the industry. For the effective adoption of these measures in the convention industry, the measures is analyzed by considering the properties and degrees of some convention centers respectively after the strength and weakness of each measure shall be compared. As these measures are mostly shore-run projects, there will be necessary to keep in close touch with other complementary measures in adoption of measures of promotion.

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Effects of Rare-earth Fertilizer on the Shoot Cuttings' Rooting of Vitex rotundifolia L. and Tamarix chinensis Lour. (희토광물계 비료가 순비기나무와 위성류의 삽목 발근에 미치는 영향)

  • Park, Chong Min;Jang, Kyu Kwan
    • Korean Journal of Environment and Ecology
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    • v.29 no.6
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    • pp.842-849
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    • 2015
  • This study investigated the effects of rare-earth fertilizer on the shoot cuttings' rooting of Vitex rotundifolia L. and Tamarix chinensis Lour. The shoot cutting test was carried in 2008 and the main results are summarized as follows. The rate of rooting and the average roots increased in both number and length when rare-earth fertilizer is treated in V. rotundifolia and T. chinensis in comparison to those of the untreated control plot. In particular, when rare-earth fertilizer is diluted with water 1/2500, the rooting outstandingly increases. This result is almost similar to the effect of the rooting stimulant, IAA. Although there is no differentiation in its rooting rate according to the density, the rooting of T. chinensis shows a 100 percent effect on in the entire treated plot but not in the untreated control plot, so it is usable as a rooting stimulant. As for shoot cuttings' rooting, depending on the time immersed in diluted solution of rare-earth fertilizer, both V. rotundifolia and T. chinensis showed relatively higher percentages in all treatment plot immersed for 60 minutes than for 10 minutes. In conclusion, considering the results of the rooting percentage and the average number and length of roots of V. rotundifolia and T. chinensis, the shoot cuttings' rooting appeared higher in percentage when they were immersed in the rooting stimulant for sixty minutes with a lower density than 1/2500. This result shows that rare-earth fertilizer can be utilized as an alterative for IAA rooting stimulants currently available in the market.

Use of Fraxnius rhynchophylla H.ance bark as antioxidant (물푸레나무 수피의 항산화 효과)

  • 김대구;이병근;김현용
    • Journal of Korea Foresty Energy
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    • v.22 no.2
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    • pp.69-77
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    • 2003
  • This study reviewed antioxidants and various enzymic physiological functions of Korean ash tree extractives that contains coumarine and ester component in order to examine the practical possibility of those materials as pharmaceutical and cosmetic additive applications. first, in the experiment of enzymic physiological activity, the electron donating ability showed 62.00% at 1ppm and over 90% at 10ppm or higher concentration, and the pseudo SOD ability showed 39% at the concentration of 2000ppm and 84.73% at the concentration of 5000ppm. Second, the inhibition activity of xanthine oxidase showed a relatively low inhibition effect of 45.57% at 200ppm, and the inhibition effect of tyrosinase showed 57.51% at 2000ppm. However, it showed a very low inhibition effect at the concentration of 500ppm or less. Third, the lipid oxidation, when Cu$\^$2+/ion was used as an oxidation accelerator, showed the inhibition effect of 82% at the concentration of 10ppm, and when Fe$\^$2+/ion was used also as the oxidation accelerator, it showed a very outstanding effect of 60% and more at 100ppm. Conclusively it is clear that the extracts of Korean ash tree bark can be used as cosmetic and pharmaceutical additive agents due to their excellent activities as antioxidant and enzymic physiological functions of it.

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How the Information Location (up vs. down) Impacts Promotion Attractiveness and Amount Perception (판매촉진 정보의 위치(위vs.아래)가 판매촉진 매력도 및 증정량 지각에 미치는 영향)

  • Jang, JungMin;Kim, Yeong-Ju
    • (The) Korean Journal of Advertising
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    • v.27 no.3
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    • pp.7-25
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    • 2016
  • According to recent studies, the location of visual information has a significant impact on consumers' interpretation and judgment in various contexts. In particular, vertical positioning is relevant to the perception of weight: consumers tend to interpret that products are heavier when information is placed at the bottom of a page or section rather than the top. This is due to the common perception that heavy things would sink to the bottom and light things would float up. Consistent with this research stream, the current study investigates how the vertical location of freebie information influences promotion evaluation. We hypothesize that consumers assume that the complimentary product is heavier when the information about it is displayed at the bottom compared to when the information is displayed at the top. Two experiments were conducted. In experiment 1, we show how the location of "get one free" information impacts the evaluation of the sales promotion in a "Buy two and get one free" context. When the complimentary information was displayed below rather than above the main product information, consumers evaluated the sales promotion more favorably. Experiment 2 tests the generalizability of the vertical location effect by using a different type of information and product: a visual picture of vitamin tablets rather than the numeric information as in Experiment 1. The dependent variable was also extended to the perceived amount of the promoted product. We suggest the boundary condition that the proposed effect is moderated by the presence or absence of an explicit message about the amount. Without an explicit message about the amount of the product, the results were similar to those of experiment 1 in that consumers perceived that the product offered a greater amount when the complimentary information was displayed at the bottom rather than at the top. However, the location effect disappeared with an explicit message about the amount. This confirms the moderating effect that presenting an explicit message about the amount is a crucial boundary condition for location effect in a value added promotion. Marketers can use this knowledge to formulate strategies in a variety of sales promotion conditions.