• Title/Summary/Keyword: 초평면

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The Usefulness of Diagnostic Scan Using Technetium-99m Pertechnetate Scintigraphy prior to the First Ablative Radioiodine Treatment in Patients with Well Differentiated Thyroid Carcinoma: A Comparative Study with Iodine-131 (분화된 갑상선암 수술 후 초치료에 있어서 Tc-99m Pertechnetate을 이용한 진단 스캔의 유용성: Iodine-131 스캔과의 비교)

  • Yoon, Seok-Nam;Park, Chan-H.;Hwang, Kyung-Hoon;Kim, Su-Zy;Soh, Eui-Young;Kim, Kyung-Rae
    • The Korean Journal of Nuclear Medicine
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    • v.34 no.4
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    • pp.285-293
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    • 2000
  • Purpose: A prospective comparison was made between imaging with Tc-99m pertechnetate (Tc-99m) and Ioine-131 (I-131) for the detection of residual and metastatic tissue after total thyroidectomy in patients with well-differentiated thyroid carcinoma. Materials and Methods: Initially our patients had imaging with Tc-99m, followed by I-131 within 3 days. The study included 21 patients who had ablation with high dose of I-131 ranging from 100 mCi to 150 mCi. Planar and pinhole images were acquired for both Tc-99m and I-131. Diagnostic images of Tc-99m and I-131 were compared with post-therapy images. Degree of uptake on Tc-99m and I-131 images was scored by four point scale and compared. Results: The results of the Tc-99m study were: 16 of 19 studies (84%) were positive on simple planar images, but 19 of 20 studies (95%) were positive on pinhole images. Conventional I-131 diagnostic imaging on the other hand showed that all studies (100%) were positive on both planar and pinhole images. There was a significant difference in degree of uptake between Tc-99m and I-131 planar images (p<0.05). Only one case of Tc-99m scintigraphy was negative on both planar and pinhole studies (false negative). There was no distant metastasis on the therapeutic I-131 images. Conclusion: Tc-99m scan using pinhole in certain clinical situations is an alternative to the I-131 scan in detecting thyroid or lymph node metastasis prior to the first ablative treatment after thyroidectomy for well-differentiated thyroid carcinoma.

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Estimating a Range of Lane Departure Allowance based on Road Alignment in an Autonomous Driving Vehicle (자율주행 차량의 도로 평면선형 기반 차로이탈 허용 범위 산정)

  • Kim, Youngmin;Kim, Hyoungsoo
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.15 no.4
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    • pp.81-90
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    • 2016
  • As an autonomous driving vehicle (AV) need to cope with external road conditions by itself, its perception performance for road environment should be better than that of a human driver. A vision sensor, one of AV sensors, performs lane detection function to percept road environment for performing safe vehicle steering, which relates to define vehicle heading and lane departure prevention. Performance standards for a vision sensor in an ADAS(Advanced Driver Assistance System) focus on the function of 'driver assistance', not on the perception of 'independent situation'. So the performance requirements for a vision sensor in AV may different from those in an ADAS. In assuming that an AV keep previous steering due to lane detection failure, this study calculated lane departure distances between the AV location following curved road alignment and the other one driving to the straight in a curved section. We analysed lane departure distance and time with respect to the allowance of lane detection malfunction of an AV vision sensor. With the results, we found that an AV would encounter a critical lane departure situation if a vision sensor loses lane detection over 1 second. Therefore, it is concluded that the performance standards for an AV should contain more severe lane departure situations than those of an ADAS.

The Effects of Tunnel Geometrical Characteristics and Canopy Installation on the Ventilation and Fire Propagation (터널의 기하학적 형태 및 캐노피 설치가 터널 환기 및 화재 확산에 미치는 영향 분석)

  • Lee, Chang-Woo;Suh, Ki-Yoon;Kim, Jung-Wook
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.8 no.4
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    • pp.325-334
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    • 2006
  • Understanding the airflow characteristics within the canopy structure installed between closely adjacent tunnels either for light adaptation or for protection from snow hazards is required for the normal ventilation as well as safety system design. Grade, horizontal alignment, cross-sectional area and shape are known to substantially influence the fire smoke behavior and their influences raise great concern for the safety design. This paper aims at studying the effects of tunnel geometrical characteristics and canopy installation on the ventilation and fire propagation through CFD analysis. In the case of 145m long canopy, 50% opening ratio is preferred with respect to the airflow pattern and ventilation efficiency. When a 20MW fire occurs in a 1.8km-long tunnel and four 1250mm reversible jet fans are instantly turned on, smoke concentration at 40m downstream of the fire decrease 13% for the upgrade tunnel with 2% gradient and increases 20% for -2% gradient, compared to the standard horizontal tunnel. Backlayering is observed within 45m-long segment toward the entrance in 2% down-graded tunnel. In a rectangular tunnel, there is no significant difference of smoke concentration as well as velocity profile from the standard crown tunnel. Three-laned tunnel shows lower level of both profiles and backlayering is detected up to 50m upstream of the fire, while the risky situation rapidly disappears thereafter.

대면적 기판 위에서의 서브마이크로미터 주기와 크기를 갖는 홀 패턴 형성을 위한 포토리소그라피 공정 최적화

  • Kim, Do-Hyeong;Bae, Si-Yeong;Lee, Dong-Seon
    • Proceedings of the Korean Vacuum Society Conference
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    • 2010.08a
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    • pp.244-245
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    • 2010
  • 최근 광전자 분야에서는 미래 에너지 자원에 대한 관심과 함께 GaN 기반 발광다이오드 및 태양전지 연구가 활발히 진행되고 있다. GaN는 높은 전자 이동도와 높은 포화 속도 등의 광전자 소자에 유리한 특성을 가지고 있으나, 고 인듐 함유량과 막질의 우수한 특성을 동시에 구현하는 것은 매우 어렵다. 이를 극복하기 위한 방법으로써 선택 영역 박막 성장법(Selective Area Growth)은 마스크 패터닝을 통해 제한된 영역에서만 박막을 성장하는 방법으로써 GaN의 막질을 향상 시킬 수 있는 방법으로 주목받고 있다. 본 논문에서는 대면적 기판에서 GaN의 막질 향상뿐만 아니라 고인듐 InGaN 박막 성장을 위하여 서브마이크로미터 주기와 크기를 갖는 홀 패턴을 포토리소그라피 공정 최적화를 통해 구현할 수 있는 방법에 대해 논의한다. 그림. 1은 사파이어 기판 위에 선택 영역 박막 성장법을 이용하여 성장한 n-GaN/활성층/p-GaN의 구조를 나타낸 그림이다. 이를 통하여 서브마이크로미터 스케일의 반극성 InGaN면 위에 높은 인듐 함유량을 가지면서도 우수한 특성을 갖는 박막을 얻을 수 있다. 본 실험을 위하여 사파이어 기판 위에 SiO2를 증착한 후 포토레지스트(AZ5206)을 도포하고 포토리소그라피 공정을 진행하여 2um 크기 및 간격을 갖는 패턴을 형성했다. 그림. 2는 AZ5206에 UV를 조사(5초)하고 현상(23초)한 패턴을 윗면(그림. 2(a))과 $45^{\circ}$ 기울인 면(그림. 2(b)) 에서 본 SEM(Scanning Electron Microscope) 사진이다. 이를 통해 약 2.2um의 홀 패턴이 선명하게 형성 됨을 볼 수 있다. 그 후 수백나노 직경의 홀을 만들기 위해서 리플로우 공정을 수행한다. 그림. 3은 리플로우 온도에 따른 패턴의 홀 모양을 AFM(Atomic Force Microscope)을 이용하여 측정한 표면의 사진이다. 이를 통해 2차원 평면에서 리플로우 온도 및 시간에 따른 변화를 볼 수 있다. 그림.3의 (a)는 리플로우 공정을 진행하기 전 패턴이고, (b)는 $150^{\circ}C$에서 2분, (c)는 $160^{\circ}C$에서 2분 (d)는 $170^{\circ}C$에서 2분 동안 리플로우 공정을 진행한 패턴이다. $150^{\circ}C$$160^{\circ}C$에서는 직경에 큰 변화가 없었고, $160^{\circ}C$에서는 시료별 현상 시간 오차에 따라 홀의 크기가 커지는 경향이 나타났다. 그러나 $170^{\circ}C$에서 2분간 리플로우 한 시료 (그림. 3(d))의 경우는 홀의 직경이 ~970nm 정도로 줄어든 것을 볼 수 있다. 홀의 크기를 보다 명확히 표현하기 위해 그림.3에 대응시켜 단면을 스캔한 그래프가 그림.4에 나타나 있다. 그림.4의 (a) 및 (b)의 경우 포토레지스트의 높이 및 간격이 일정하므로, 리플로우에 의한 영향은 거의 없었다. 그림. 4(c)의 경우 포토레지스트의 높이가 그림.4(a)에 비해 ~25nm 정도 낮은 것으로 볼 때, 과도 현상 및 약간의 리플로우가 나타났을 가능성이 크다. 그림. 4(d)에서는 ~970nm의 홀 크기가 나타나서 본 연구에서 목표로 하는 나노 홀 크기에 가장 가까워짐을 확인할 수 있었다. 따라서, $170^{\circ}C$ 이상의 온도와 2분 이상의 리플로우 시간 조건에서 선택 영역 성장을 위한 나노 홀 마스크의 크기를 제어할 수 있음을 확인하였다.

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Analysing Astronomical Thinking of Elementary, Middle, and High School Students Using Ordered Multiple Choice Items (순위 선다형 문항을 이용한 초·중·고등학생의 천문학적 사고 분석)

  • Choi, Joontae;Lee, Kiyoung;Park, Jaeyong
    • Journal of the Korean Society of Earth Science Education
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    • v.11 no.2
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    • pp.125-144
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    • 2018
  • The purpose of this study is to analyze the astronomical thinking level of elementary, middle, and high school students using ordered multiple choice items. For this purpose, we constructed a questionnaire comprising three items about spatial thinking and system thinking. This survey was conducted and applied to 1,066 students in the 5th grade, 8th grade, and 11th grade in 12 schools located in Gangwon Province. The collected student response data were analyzed by applying inferential statistics of classical test theory and Rasch model. The results of the analysis were as follows; First, in the level of spatial thinking, students were able to grasp the spatial location and orientation of the celestial body, but were not able to convert the celestial motion of two-dimensional plane into three-dimensional plane, and it was revealed that there is no statistically significant difference in the spatial thinking of students among grade levels. Second, in the level of system thinking, students were able to identify the components and relationship between components of the celestial motion system, but could not identify the patterns of the system, and it was revealed that there was statistically significant difference among the system thinking of students in different grade levels, unlike in spatial thinking. Third, the astronomical thinking expressed in certain context (content) was very similar regardless of grade level, Through this, we could confirm the context-dependency or content-dependency of the astronomical thinking of students. It is expected that the results of this study can be used as basic data for exploring ways to enhance astronomical thinking level in school science classes.

Signal Peptide Cleavage Site Prediction Using a String Kernel with Real Exponent Metric (실수 지수 메트릭으로 구성된 스트링 커널을 이용한 신호펩티드의 절단위치 예측)

  • Chi, Sang-Mun
    • Journal of KIISE:Software and Applications
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    • v.36 no.10
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    • pp.786-792
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    • 2009
  • A kernel in support vector machines can be described as a similarity measure between data, and this measure is used to find an optimal hyperplane that classifies patterns. It is therefore important to effectively incorporate the characteristics of data into the similarity measure. To find an optimal similarity between amino acid sequences, we propose a real exponent exponential form of the two metrices, which are derived from the evolutionary relationships of amino acids and the hydrophobicity of amino acids. We prove that the proposed metric satisfies the conditions to be a metric, and we find a relation between the proposed metric and the metrics in the string kernels which are widely used for the processing of amino acid sequences and DNA sequences. In the prediction experiments on the cleavage site of the signal peptide, the optimal metric can be found in the proposed metrics.

Study on Support Vector Machines Using Mathematical Programming (수리계획법을 이용한 서포트 벡터 기계 방법에 관한 연구)

  • Yoon, Min;Lee, Hak-Bae
    • The Korean Journal of Applied Statistics
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    • v.18 no.2
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    • pp.421-434
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    • 2005
  • Machine learning has been extensively studied in recent years as effective tools in pattern classification problem. Although there have been several approaches to machine learning, we focus on the mathematical programming (in particular, multi-objective and goal programming; MOP/GP) approaches in this paper. Among them, Support Vector Machine (SVM) is gaining much popularity recently. In pattern classification problem with two class sets, the idea is to find a maximal margin separating hyperplane which gives the greatest separation between the classes in a high dimensional feature space. However, the idea of maximal margin separation is not quite new: in 1960's the multi-surface method (MSM) was suggested by Mangasarian. In 1980's, linear classifiers using goal programming were developed extensively. This paper proposes a new family of SVM using MOP/GP techniques, and discusses its effectiveness throughout several numerical experiments.

Development of Traffic Prediction and Optimal Traffic Control System for Highway based on Cell Transmission Model in Cloud Environment (Cell Transmission Model 시뮬레이션을 기반으로 한 클라우드 환경 아래에서의 고속도로 교통 예측 및 최적 제어 시스템 개발)

  • Tak, Se-hyun;Yeo, Hwasoo
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.15 no.4
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    • pp.68-80
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    • 2016
  • This study proposes the traffic prediction and optimal traffic control system based on cell transmission model and genetic algorithm in cloud environment. The proposed prediction and control system consists of four parts. 1) Data preprocessing module detects and imputes the corrupted data and missing data points. 2) Data-driven traffic prediction module predicts the future traffic state using Multi-level K-Nearest Neighbor (MK-NN) Algorithm with stored historical data in SQL database. 3) Online traffic simulation module simulates the future traffic state in various situations including accident, road work, and extreme weather condition with predicted traffic data by MK-NN. 4) Optimal road control module produces the control strategy for large road network with cell transmission model and genetic algorithm. The results show that proposed system can effectively reduce the Vehicle Hours Traveled upto 60%.

A Study on the Extraction of Parasitic Capacitance for Multiple-level Interconnect Structures (다층배선 인터커넥트 구조의 기생 캐패시턴스 추출 연구)

  • 윤석인;원태영
    • Journal of the Korean Institute of Telematics and Electronics D
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    • v.36D no.5
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    • pp.44-53
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    • 1999
  • This paper are reported a methodology and application for extracting parasitic capacitances in a multi-level interconnect semiconductor structure by a numerical technique. To calculate the parasitic capacitances between the interconnect lines, we employed finite element method (FEM) and calculated the distrubution of electric potential in the inter-metal layer dielecric(ILD) by solving the Laplace equation. The three-dimensional multi-level interconnect structure is generated directly from two-dimensional mask layout data by specifying process sequences and dimension. An exemplary structure comprising two metal lines with a dimension of 8.0$\times$8.0$\times$5.0$\mu\textrm{m}^3/TEX>, which is embedded in three dielectric layer, was simulated to extract the parasitic capacitances. In this calculation, 1960 nodes with 8892 tetrahedra were used in ULTRA SPARC 1 workstation. The total CPU time for the simulation was 28 seconds, while the memory size of 4.4MB was required.

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A Study on the Effects on Low Cycle Fatigue Life of a High Pressure Turbine Nozzle due to the Perturbation of Crystal Orientation of Grain of DS Materials (일방향 응고 재료의 결정립 성장 방향 섭동이 고압터빈 노즐 저주기 피로 수명에 미치는 영향에 대한 연구)

  • Huh, Jae Sung;Kang, Young Seok;Rhee, Dong Ho
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.40 no.7
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    • pp.653-658
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    • 2016
  • High pressure components of a gas turbine engine are generally made of nickel-base superalloys, using precision casting process due to complicated geometries with intricate channels and cooling holes. Turbine components manufactured from directionally solidified and single crystal materials have columnar grains; however, it is found that the crystals do not grow in its preferred direction, although the orientation can be controlled. This anisotropy can lead to the variations of elastic and Hill's parameters in constitutive equations, and they alter stress distributions and the low cycle fatigue life. We aims to evaluate the effects of perturbed crystal orientations on the structural integrity of a directionally solidified nozzle using low cycle fatigue life. We also attempt to show the necessity for the control of allowed manufacturing errors and stochastic analysis. Our approaches included conjugate heat transfer and structural analysis, along with low cycle fatigue life assessment.