Purpose : Helicobacter pylori infection is one of the most common gastrointestinal infections worldwide; it almost invariably causes chronic gastritis. Pediatric studies may provide important insights into the mucosal immune response of H. pylori-infection, as children are not submitted to environmental factors such as alcohol, tobacco and anti-inflammatory medication. The aim of the present study was to investigate the mucosal immune response against H. pylori in clinically well-defined groups: H. pylori-positive (divided into peptic ulcer disease and gastritis) and H. pylori-negative control. Methods : Antral biopsies were obtained from 45 children undergoing an upper GI endoscopy for dyspeptic symptoms. T cells (CD3+, CD4+, CD8+) and B cells (CD20+) were analyzed by quantitative immunohistochemistry. The correlation of lymphocyte subsets of gastric mucosa with histology was evaluated. Results : T cells (CD3+, CD4+, CD8+) and B cells (CD20+) were significantly increased in the lamina propria of H. pylori-positive group (P<0.01). CD8+ T cells were significantly increased in the lamina propria of the H. pylori-positive peptic ulcer disease (P<0.01). Within the epithelium, only CD4+ T cells were significantly increased in the H. pylori-positive group (P<0.01). Gastric histological parameters had a closer correlation with lymphocytes in the lamina propria than intraepithelial lymphocytes. Conclusion : This study suggests that both T cells and B cells in the lamina propria play important roles in the local immune response of H. pylori-infected children. Furthermore, it remains to be elucidated whether CD8+ T cells in the lamina propria may contribute to peptic ulcer formation in H. pylori-infected children.
Silica sorption isotherm belonged to the C-type with weak L-type characteristics according to the classification system of adsorption isotherm. Silica sorption isothem fitted well to the Freundlich and Tempkin equation but not to the Langmuir equation. The color interference probably due to $Fe^{2+}$ during spectrometric silca determination by Molybdenum-blue method affected the sorption isotherm in reduced soils or low pH. Four parameters such as the intercept of Freundlich equation, the slope of Tempkin equation, the "Silica reactivity", and the "C-type slope", where the last two parameters were termed in the current study, were examined to assess treatment effects on silica sorption. Among them the "C-type slope" was found out to be the best parameter. The C-type isotherms showed the same high correlation coefficient as Freundlich and Tempkin equation when regressed to the sorption isothem. Plotting the C-type slope on a logarithmic scale vs. the pH showed high linearity. Using the "C-type slope" as a perameter, the pH and soil type affected the silica sorption while the effect of redox condtion was not significant. All Fe and Al extracted by the various reagents, and OM were highly correlated to silica sorption. Among them $Fe_d$ was identified as the highest influencing soil property. Since there is no equivalent reliable method to discriminate the forms of the soil Al-oxides their likely importance remains unclear.
To establish the best rice cultivating system in the aspects of environment-loving agriculture, the amounts and patterns of nitrogen leached in the paddy soil were investigated with 7 treatments; Recommendation(R), Farmer's usual practice(FUP), Straw compost+chemical fertilizers reduced(SCF), Fresh straw+recommendation(FSC), Fresh cow manure(FCM), Cow manure compost(CMC), and no fertilization as Control(C). And SCF, FCM and CMC were applied with same amounts of total nitrogen to R. The infiltrated water samples were collected in ceramic porous cups which were buried at 60cm depth from the top. Concentrations of nitrate-N in irrigated water were $1.3mg\;l^{-1}$ on rice transplanting season when nutrients began to elute from paddy soil, and $0.4mg\;l^{-1}$ after breaking off irrigation. But it was $4-6mg\;l^{-1}$ in rice growing period. The maximum concentration of nitrate-N in leachate was not more than $7mg\;l^{-1}$ during rice cultivation. The amounts of nitrogen leached in R, FUP, SCF, FSR, FCM, CMC and C were 59, 63, 25, 41, 24, 27, $17kg\;ha^{-1}y^{-1}$ respectively. Nitrogen leaching was decreased to about 30% by supplement of fresh rice straw(FSC) to R. Furthermore, it was possible to reduce to over 50% of nitrogen leaching by reducing chemical fertilizer application(CF), or by substituting of chemical fertilizers with fresh cow manure(FCM) or cow manure compost(CMC). In added organic fertilizer treatments, the amounts of infiltrated nitrogen were less $13-46kg\;ha^{-1}y^{-1}$ than that of input by irrigation. This experiment showed that nutrients leaching was minimized by substitution of chemical fertilizers with organic fertilizer or by application of straw with chemical fertilizers in rice paddy soil and rice cultivation with suitable fertilizer management can work as a purifier rather than contaminator of water.
Journal of the Korean Society of Food Science and Nutrition
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v.39
no.3
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pp.474-479
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2010
The content levels of taurine, DHA, and EPA of dried cuttlefish powder were $11.67{\pm}6.62\;g/kg$, $3001.11{\pm}11.42\;mg/100\;g$ and $688.13{\pm}10.51\;mg/100\;g$, respectively, which were 10~20% higher than those of the salt processed cuttlefish. After feeding dried and salt processed cuttlefish for 4 weeks, total cholesterol concentrations in mice blood were 81.3 mg/dL and 88.1 mg/dL, respectively, which was higher than 78.9 mg/dL of the control. It was also found that dried cuttlefish increased HDL-cholesterol concentrations to 71.6 mg/dL, compared to 63.1 mg/dL of salt processed cuttlefish. The triglyceride contents of dried sample was higher than that of processed sample. Blood glucose concentrations in mice fed dried or salt processed cuttlefish were 77.7 mg/dL and 90.3 mg/dL, respectively. IgG levels increased to 48.1 ng/mL by feeding the processed cuttlefish, compared to 40.3 ng/mL of the dried cuttlefish. Therefore, by analysis of serum lipid, it can be suggested that processed cuttlefish can improve immune activities through adding taurine and polyunsaturated fatty acids.
Journal of the korean academy of Pediatric Dentistry
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v.41
no.3
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pp.257-265
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2014
The aim of this study was to establish the appropriate guidelines in the sedation techniques and to organize the continuing education programs for the sedation in future under the direction of Committee on Sedation, Education and Research under the Korean Academy of Pediatric Dentistry(KAPD). The surveys on the sedation technique were performed on 111 organizations which practices the sedation and responded to the survey via online and e-mail by February 2014. The collected survey were analyzed. The purpose of sedation was mainly to manage the children's behavior and its uses were primarily on 3~4 years old children. The most frequent duration of treatment was 1~2 hours to treat both maxillary and mandible. The preferred dosages of sedative drugs were chloral hydrate(CH) 50~70 mg/kg, hydorxyzine(Hx) 1~2 mg/kg, and intramuscular midazolam(Mida IM) 0.1~0.2 mg/kg. The preferred combination of the sedative drugs were CH + Hx + $N_2O/O_2$(67.6%), CH + Hx + Mida submucosal administration (SM) + $N_2O/O_2$(29.7%), and Mida IM + $N_2O/O_2$(23.4%). The administration of additional sedatives was carried out at 48%, mainly using Midazolam. 87.5% of the respondents experienced the adverse effects of the sedation such as vomiting/retching, agitation during recovery, subclinical respiratory depression, staggering, and etc. Among them, only 20% periodically retrain the emergency management protocol. About the discharge criteria for patients after the sedation, the respondents either showed a lack of clear criteria or did not follow the recommended discharge criteria. 86% of the respondents expressed the interests in taking a course on the sedation and they wanted to learn mostly about the sedation-related emergency management, the safe dosage of the sedative drugs, and etc. The use of sedation in pediatric dentistry must be consider a patient's safety as top priority and each dentist must show the evidence of sound practices for the prevention of any possible medical errors. Therefore, KAPD must establish the proper sedation guidelines and it needs to provide the systematic technical training program of sedation-related emergency management for pediatric dentists.
Journal of the Korean association of regional geographers
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v.4
no.2
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pp.31-47
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1998
This paper deals with the historical geography of land-use and agriculture along the Lower Nam-River floodplains. The reclamation process of the river floodplains, the cultivation methods on the reclaimed lands, and the land-use patterns and processes are investigated. The Nam River, one of the major tributaries of the Nakdong River, flows through the boundary between Ham-An and Eu-Ryong Guns. Larger floodplains are located in Ham-An Gun. The floodplains of Ham-An Gun have been surveyed intensively in this study. In South Korea, the alluvial plains, mostly located along the river valleys, have been reclaimed to provide fertile agricultural lands. Those along the upper river valleys were reclaimed before those along the lower river valleys. The flood-plains of Han-An Gun were reclaimed to be the largest agricultural lands of the Gun. The natural levees along the Lower Nam-River Valley were identified before the reclamation processes but now hardly identified. Relatively larger floodplains are located along the tributary streams of the Nam River. Often there are low-lying back swamps between the natural levees and the hills/mountains that rise above the floodplains. The back swamps, called 'natural bog lands' in this region, have been reduced in size and in number through reclamation for the purpose of agricultural and industrial land-uses. Now about ten 'natural bog lands' are found in the Ham-An floodplains, and some of them are being reclaimed for the industrial land-use. This study suggests the emergent need of conservation for the remaining 'natural bog lands' in terms of ecology. Seven agricultural fields of large size, originated from the Nam-River floodplains, are identified in this study: Kun(큰들), Chung-Am(정암들), Chang-chi(장지들), Baek-San(백산들), Ha-Ki(하기들), Gu-Hae(구혜들), and Chang-Po(장포들) fields. The Kun field was reclaimed during the Japanese control and the Gu-Hae, in the 1950s. All of those except the above two fields were reclaimed after the mid-1960s. The Nam-River Dam in Chinju, completed in 1969, contributed the reclamation processes along the Lower Nam-River floodplains. The rice acreage of the region has been reduced slowly since 1970 but the rice production of the region has been relatively stable (Table 4). Rice culture had been the most important agriculture on the reclaimed lands for decades before the greenhouse vegetable cultivation became more important in the 1980s. Among the vegetables cultivated in the greenhouse, the watermelon is the dominantly leading one. Watermelons are usually harvested two or three times in a year though it is possible to harvest four times in one year. The rotation of watermelons and rice is common in the region. It is known the physical conditions of the Nam-River floodplains in Ham-An Gun is the most suitable for watermelon cultivation in South Korea.
Park, Hoon-Sub;Oh, Hee-jin;Kwon, Min-Young;Kang, Min-Jeong;Eun, Tae-Kyung;Seo, Min-Cheol;Oh, Jong-Kil;Kim, Eui-Joong;Joo, Eun-Jeong;Bang, Soo-Young;Lee, Kyu Young
Korean Journal of Psychosomatic Medicine
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v.23
no.1
/
pp.36-46
/
2015
Objectives: To understand the risk factors of demographic data in geriatric depression scale, and suicidality among in elderly who live alone at one urban region. Methods:In 2009, 589 elderly who live alone(age${\geq}$65) were carried out a survey about several socio-demographic data, Korean version of the Geriatric Depression Scale(SGDS-K) and Suicidal Ideation Questionnaire (SIQ). Statistical analysis was performed for the collected data. Results: Mean age of elderly who live alone is 75.69(SD 6.17). 40.1% of participants uneducated, 31.4% graduate from elementary school, 12.9% graduate from high school, 11.7% graduate from middle school, 3.2% graduate from university. Religionless, having past history of depression or physical diseases, low subjective satisfaction of family situation, and not having any social group activity have significance to depressive symptoms of elderly who live alone. Having past history of depression, religionless, low subjective satisfaction of family situation have significance to suicidality. Especially, low subjective satisfaction of family situation and having past history of depression are powerful demographic factor both depressive symptoms and suicidality of elderly who live alone. Conclusions: When we take care elderly who live alone, we should consider many things, but especially the social support network such as family satisfaction and past history of depression for reducing or preventing their depression and suicide both elderly depression and suicide who live alone.
The 'Jwasuyeongseongji' (Site of naval wall-fortress in Suyeong) in Busan is the subject of this study. It has been desturbed mostly, and is named 'Suyeong historic site'. One of the important aspects of 'Jwasuyeongseongji' is that it was a historic place confronting with the Japanese Invasion of Chosun in 1592. This was the place where the Japanese Invasion of Chosun broke out and a number of people were slaughtered by the Japanese invaders. Now the place is converted to a playground. Although 'Jwasuyeongseongji' is the place of historic interest, the forest area is separated by paths and sidewalks. Further, there are sports facilities and relaxing people. Examples of advanced countries show that the abuse like Jwaisuyeongseongji is thoroughly prohibited. Although the Dangsan forest of jwasuyeongseongji remains in the megalopolis of Busan, it has been damaged and abused in spite of being a historic site. Nevertheless, Jwasuyeongseongji is an invaluable traditional cultural heritage. The objective of this study was to search for solutions of authenticity restoration for the remains of Dangsan forest at Jwasuyeongseongji in Busan. The Dangsan forest at Jwasuyeongseongji is a forest of Pinus thunbergii in an area of $130{\times}230m$. Jwasuyeongseongji is currently named Suyeong historic park, and is registered as monuments No. 8 by Suyeong-gu, Busan. The two Dangsan trees at Jwasuyeongseongji are registered as natural monuments No. 270 and No. 311. The complex management system needs to be designated as 'Dangsan forest of Jwasuyeongseongji in Busan', and managed as a natural monument or national historic site. Dangsan forest has a meaning of divine place. Therefore, the artificial facilities need to be removed from Dangsan forest so that the original features are restored with the spirit of Jwasuyeongseongji. Also, the administration needs to be transfered from Suyeong-gu, Busan to the Cultural Heritage Administration.
Since the advent of tertiary curriculum, middle school history education has been focused on political history, but many students perceive history as a simple memorization subject and complain about difficulties in abstract learning. The researcher saw this problem as caused by the history curriculum, and carried out this study for the purpose of proposing a revitalization of cultural property education in the middle school history curriculum. First, through the analysis of prior research, the usefulness of cultural property education, such as nurturing creative talent and realizing interactive history classes, was revealed, and the problems of the current political history-centered middle school history curriculum were pointed out. Afterwards, as a result of conducting an opinion survey on middle school 3rd grade students and social studies teachers, it was found that first, both middle school students and their teachers thought that the current political history-centered history had much room for improvement. Second, all groups agreed on the necessity of cultural property education in history education. However, in reality, it was found that it was not easy to sufficiently educate students about cultural property in a political history-centered curriculum. Third, teachers thought that it was necessary to improve the current history curriculum in order to enhance cultural property education. Based on these findings, the researcher suggested an improvement plan for the 2015 revised history curriculum. First, in the 'nature of the subject' section, cultural properties and historical materials should be included, and in the 'objective' section, politics, economy, society, and culture should be included. Contents related to cultural properties should be added to the sub-themes in the 'content system and achievement standards', and cultural properties-related contents should be further reinforced in the achievement standards, 'teaching, learning and evaluation'. It was suggested that this section should include cultural property learning and historical material learning, and guidance on teaching and learning methods of cultural property education should be added. If these aspects are reflected in the 2022 revised curriculum that is currently being developed, cultural property education will be improved, and more lively history education will be provided to students.
The Journal of Sustainable Design and Educational Environment Research
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v.20
no.2
/
pp.1-10
/
2021
The results of research and analysis are as follows: First, there were 108 types of change patterns in the number of elementary school students. Second, based on the similarity of 108 types of change patterns in the number of students, a type system diagram was presented. Third, in the case of a total of 18 types of change patterns in the number of students, the number of students decreased significantly due to the establishment of additional schools on top of the existing schools. The result of a a long-term survey and analysis on the trend of increase and decrease in the number of students across the country shows an urgent need todevelop policy tasks across the entire school accommodation plan, such as the establishment of differentiated schools suitable for regional characteristics, relocation, consolidation, reorganization of school districts, remodeling, and appropriatization projects.
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