• Title/Summary/Keyword: 창상피복제

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Coating properties of PPG-based Polyurethane Dispersion wound covering resin by Addition of PVA (PVA의 첨가에 의한 PPG기반 수분산 창상피복수지의 코팅 물성)

  • Lee, Joo-Youb
    • Journal of the Korean Applied Science and Technology
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    • v.38 no.1
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    • pp.178-185
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    • 2021
  • In this study, polyvinyl alcohol (PVA) and polypropylene glycol (PPG)-based polyurethane dispersion resin for wound coating was synthesized. And the physical properties of the sample were coated on the surface of the film sample and the leather (Full-Grain) to study the physical properties change. In the case of tensile strength, PUD-PA1, which reacted with the least amount of PVA, showed the highest resistance at 2.00 kgf/㎟. Likewise, the rate of elongation was measured as high as 554% for PUD-PA1, which reacted with the least amount of PVA. The abrasion resistance measurement result showed that as the PVA response increased, the strength of the surface decreased to 36.77 mg.loss.

Electrospinning of Asiaticoside/2-Hydroxypropyl-β-cyclodextrin Inclusion Complex-loaded Cellulose Acetate Fiber Mats: Release Characteristics and Potential for Use as Wound Dressing (Asiaticoside/2-Hydroxypropyl-β-cyclodextrin 포접화합물 함유 셀룰로오스 아세테이트 섬유 매트의 전기방사: 창상피복제로서 사용가능성과 방출특성)

  • Panichpakdee, Jate;Pavasant, Prasit;Supaphol, Pitt
    • Polymer(Korea)
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    • v.38 no.3
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    • pp.338-350
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    • 2014
  • Cellulose acetate (CA) fiber mats containing inclusion complexes of asiaticoside (AC) in 2-hydroxypropyl-${\beta}$-cyclodextrin ($HP{\beta}CD$) for potential usage as wound dressings were developed. The AC/$HP{\beta}CD$ complex-loaded CA fibers at various $HP{\beta}CD$ to AC molar ratios of 0.5, 1, and 2 were prepared in 90:10 v/v mixture of 80% (v/v) acetic acid and N,N-dimethylacetamide (DMAc) via electrospinning. The maximum released amounts of AC depended on the $HP{\beta}CD$ content and were much greater than those released from the AC-loaded CA fiber mat. In the in vitro study, indirect cytotoxic evaluation with human dermal fibroblasts (HDFa) showed that these materials released no substances in the levels that were harmful to the cells and the cells appeared to attach and proliferate well on these substrates. However, only the CA fiber mats containing AC/$HP{\beta}CD$ complexes at the $HP{\beta}CD$ to AC molar ratio of 0.5 was effective in upregulating the production of collagen of the cultured cells.