• Title/Summary/Keyword: 질병 예측

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Generating high resolution of daily mean temperature using statistical models (통계적모형을 통한 고해상도 일별 평균기온 산정)

  • Yoon, Sanghoo
    • Journal of the Korean Data and Information Science Society
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    • v.27 no.5
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    • pp.1215-1224
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    • 2016
  • Climate information of the high resolution grid units is an important factor to explain the phenomenon in a variety of research field. Statistical linear interpolation models are computationally inexpensive and applicable to any climate data compared to the dynamic simulation method at regional scales. In this paper, we considered four different linear-based statistical interpolation models: general linear model, generalized additive model, spatial linear regression model, and Bayesian spatial linear regression model. The climate variable of interest was the daily mean temperature, where the spatial variability was explained using geographic terrain information: latitude, longitude, elevation. The data were collected by weather stations in January from 2003 and 2012. In the sense of RMSE and correlation coefficient, Bayesian spatial linear regression model showed better performance in reflecting the spatial pattern compared to the other models.

AptaCDSS - A Cardiovascular Disease Level Prediction and Clinical Decision Support System using Aptamer Biochip (AptaCDSS - 압타머칩을 이용한 심혈관질환 질환단계 예측 및 진단의사결정지원시스템)

  • Eom, Jae-Hong;Kim, Byoung-Hee;Lee, Je-Keun;Heo, Min-Oh;Park, Young-Jin;Kim, Min-Hyeok;Kim, Sung-Chun;Zhang, Byoung-Tak
    • Proceedings of the Korean Information Science Society Conference
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    • 2006.10a
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    • pp.28-32
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    • 2006
  • 최근 연구결과에 의하면 심장질환을 포함한 심혈관질환은 성별에 관계없이 미국 및 전 세계적으로 질병사망의 주요 원인으로 조사되었다. 본 연구에서는 보다 효율적으로 진단하기 위해 진단의사 결정 보조시스템에 대해서 다룬다. 개발된 시스템은 혈청 내의 특정 단백질의 상대적 양을 측정할 수 있는 바이오칩인 압타머칩을 이용해 생성한 환자들의 칩 데이터를 Support Vector Machine, Neural Network, Decision Tree, Bayesian Network 등의 총 4가지 기계학습 알고리즘으로 분석하여 질환단계를 예측하고 진단을 위한 보조정보를 제공한다. 논문에서는 총 135개 샘플로 구성된 3K 압타머칩 데이터에 대해 측정된 초기 시스템의 질환단계 분류성능을 제시하고 보다 유용한 진단의사결정 보조 시스템을 구성하기 위한 요소들에 대해서 논의한다.

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Nomogram building to predict dyslipidemia using a naïve Bayesian classifier model (순수 베이지안 분류기 모델을 사용하여 이상지질혈증을 예측하는 노모 그램 구축)

  • Kim, Min-Ho;Seo, Ju-Hyun;Lee, Jea-Young
    • The Korean Journal of Applied Statistics
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    • v.32 no.4
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    • pp.619-630
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    • 2019
  • Dyslipidemia is a representative chronic disease affecting Koreans that requires continuous management. It is also a known risk factor for cardiovascular disease such as hypertension and diabetes. However, it is difficult to diagnose vascular disease without a medical examination. This study identifies risk factors for the recognition and prevention of dyslipidemia. By integrating them, we construct a statistical instrumental nomogram that can predict the incidence rate while visualizing. Data were from the Korean National Health and Nutrition Examination Survey (KNHANES) for 2013-2016. First, a chi-squared test identified twelve risk factors of dyslipidemia. We used a naïve Bayesian classifier model to construct a nomogram for the dyslipidemia. The constructed nomogram was verified using a receiver operating characteristics curve and calibration plot. Finally, we compared the logistic nomogram previously presented with the Bayesian nomogram proposed in this study.

Disease Prediction System based on WEB (WEB 기반 질병 예측 시스템)

  • Hong, YouSik;Han, Y.H.;Lee, W.B.
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.22 no.3
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    • pp.125-132
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    • 2022
  • The Ministry of Environment recently analyzed the output data of 10 fine dust measuring stations and, as a result, announced that about 60% had an error that the existing atmospheric measurement concentration was higher. In order to accurately predict fine dust, the wind direction and measurement position must be corrected. In this paper, in order to solve these problems, fuzzy rules are used to solve these problems. In addition, in order to calculate the fine particulate sensation index actually felt by pedestrians on the street, a computer simulation experiment was conducted to calculate the fine particulate sensation index in consideration of weather conditions, temperature conditions, humidity conditions, and wind conditions.

Pulmonary Multinodular Epithelioid Hemangioendothelioma with Mixed Progression and Spontaneous Regression during a 7-Year Follow-Up: A Case Report and Review of Imaging Findings (7년간 추적관찰에서 진행과 자발적 퇴행을 함께 보인 폐의 다결절성 상피양 혈관내피종: 증례 보고 및 영상 소견 고찰)

  • Ga Young Yi;Yoo Kyung Kim;Kwan Chang Kim;Heae Surng Park
    • Journal of the Korean Society of Radiology
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    • v.83 no.4
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    • pp.958-964
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    • 2022
  • Pulmonary epithelioid hemangioendothelioma (PEH) is a rare vascular tumor of borderline or low-grade malignancy, and its prognosis is unpredictable. Herein, we describe the case of a 47-year-old asymptomatic female with a diagnosis of multinodular PEH. During a 7-year follow-up, the nodules with large size and high 18F-fluorodeoxyglucose uptake in the initial study showed progression with increasing sizes; however, most small nodules (size < 1 cm) demonstrated spontaneous regression with peripheral rim or nodular calcification. The patient underwent surgical resection for an enlarged nodule. Of note, it is unusual for an individual to have mixed progression and regression concomitantly, which may be helpful in predicting the prognosis.

Prognostic Value of Serum Ferritin in Terminally Ill Cancer Patients (말기암환자에서 예후인자로서 혈청 Ferritin의 유용성)

  • Lee, Soo Hee;Choi, Youn Seon;Hwang, In Cheol;Yeom, Chang Hwan;Lee, June Yeong
    • Journal of Hospice and Palliative Care
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    • v.18 no.1
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    • pp.51-59
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    • 2015
  • Purpose: Predicting life expectancy of terminally ill cancer patients is very important. In many studies, ferritin is detected at higher levels in the sera of cancer patients, and higher ferritin level correlates with aggressiveness of disease and poor outcomes of patients. This study evaluated a prognostic role of serum ferritin levels in terminally ill cancer patients. Methods: This study enrolled 65 terminally ill cancer patients from March through June 2012. We assessed routine laboratory findings including serum ferritin levels as well as demographic and clinical characteristics of the patients. To examine the association between serum ferritin levels and patient's characteristics, we used Spearman's correlation analysis, Wilcoxon's rank sum test or Kruskal-Wallis test, as appropriately. For multivariate analysis, Cox's proportional hazard regression model was used to evaluate significance of serum ferritin levels as a prognostic factor. Results: A negative correlation between serum ferritin levels and survival time was found. After adjusting for sex, age, performance status, creatinine levels and white blood cell counts, serum ferritin levels were significantly associated with survival time. Conclusion: Even at the very end of life of terminal cancer patients, serum ferritin levels were an independent prognostic factor for survival.

The Usefulness of Liver Fibroscan Test Using Ultrasound Image (초음파영상을 이용한 간탄력도 검사의 유용성)

  • An, Hyun;Lee, Jin-Soo;Im, In-Chul;Yang, Sung-Hee
    • Journal of the Korean Society of Radiology
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    • v.11 no.4
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    • pp.205-212
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    • 2017
  • Chronic diffuse hepatopathy is one of the important clinical tasks to reduce mortality and morbidity due to liver cirrhosis, liver failure, and liver cancer. The purpose of this study was to evaluate the criteria for predicting liver and chronic liver disease using Fibroscan based on ultrasound diagnosis. Serum and liver stiffness measurement(kPa) were analyzed in 280 patients and cut-off values of liver stiffness measurement for predicting fatty liver and chronic diffuse hepatopathy were determined using ROC curve analysis. Bilirubin and PT(prothrombin time) were not related to disease prediction(p=0.243, p=0.115). Serum glucose and triglyceride levels were significantly higher in the liver (p<0.05). The cut-off value for predicting chronic diffuse hepatopathy was determined as 10.3 kPa(AUC 0.98, sensitivity 94.94%, specificity 94.93%) in the order of control group, fatty liver and chronic diffuse hepatopathy. Therefore, it will be used as a primary tool for the diagnosis of chronic liver disease patients with quantitative evaluation.

Short-term Mortality Prediction of Recurrence Patients with ST-segment Elevation Myocardial Infarction (ST 분절 급상승 심근경색 환자들의 단기 재발 사망 예측)

  • Lim, Kwang-Hyeon;Ryu, Kwang-Sun;Park, Soo-Ho;Shon, Ho-Sun;Ryu, Keun-Ho
    • Journal of the Korea Society of Computer and Information
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    • v.17 no.10
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    • pp.145-154
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    • 2012
  • Recently, the cardiovascular disease has increased by causes such as westernization dietary life, smoking, and obesity. In particular, the acute myocardial infarction (AMI) occupies 50% death rate in cardiovascular disease. Following this trend, the AMI has been carried out a research for discovery of risk factors based on national data. However, there is a lack of diagnosis minor suitable for Korean. The objective of this paper is to develop a classifier for short-term relapse mortality prediction of cardiovascular disease patient based on prognosis data which is supported by KAMIR(Korea Acute Myocardial Infarction). Through this study, we came to a conclusion that ANN is the most suitable method for predicting the short-term relapse mortality of patients who have ST-segment elevation myocardial infarction. Also, data set obtained by logistic regression analysis performed highly efficient performance than existing data set. So, it is expect to contribute to prognosis estimation through proper classification of high-risk patients.

Comparison of the Results of Multistix$^{(R)}$SG and Comber-9-Test$^{(R)}$ RL Urine Dipstick Assay (Multistix$^{(R)}$-SG와 Comgur-9-test$^{(R)}$RL에 의한 요시험지봉검사 성적의 비교)

  • Kim, Dae-Chul;Kim, Kyung-Dong;Jung, Bo-Chan;Kim, Chung-Sook;Cho, Kil-Ho
    • Journal of Yeungnam Medical Science
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    • v.8 no.1
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    • pp.42-52
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    • 1991
  • Two types of urine dipstick assays, Multistix-SG and Combur-9-test RL, were compared for compatibility, accuracy, specificity and predictive values of a positive and negative test in 501 patients urine and artificially prepared specimen. We found that the results of semiquantitative tests of Multistix-SG and Combur-9-Test RL performed were statistically similar in patients specimen. The urinary leukocyte estrase tests of Combur-9-Test RL assays compared with urine sediment microscopy in regard to compatibility, sensitivity, specificity, and predictive values of a positive and negative test 83.7%, 48.1%, 90.3%, 47.4% and 90.1%, respectively. The urinar nitrite tests of Comber-9-Test RL assays compared with urine culture tests, in regard to compatibility, sensitivity, specificity, and predictive values of a positive and negative tests were 90.3%, 19.4%, 84.7%, 53.8% and 94.1%, respectively. For the urinary protein, the sulfosalicylic acid method was the most sensitive test for any kinds of protein, and Multistix-SG appeared more sensitive than Compur-9-Test RL for the albuminuria. For the urinary bilirubin and glusose, two dipstick assays were similar in their diganostic efficiency. Finally in the urinary occult blood tests, Combur-9-Test RL assays was more sensitive than Multistix-SG.

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Prediction Model for Toothache Occurrence in College Students by using Oral Hygiene Habits and the CART Model (대학생의 구강건강관리실태와 CART모델을 이용한 치통발생예측)

  • Kim, Nam-Song;Lim, Kun-Ok
    • Journal of dental hygiene science
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    • v.9 no.4
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    • pp.419-426
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    • 2009
  • The occurrence of toothache signals the malfunction in oral health, which allows the detection of any abnormal condition in the oral cavity at an early stage to prevent the condition from worsening, and thus can act as a preventive measure. This study has looked into the status of oral health management in relation to toothache through the structured survey administered to 235 college students. Based on the survey results, this study aimed at comparing the toothache occurrence prediction between regression analysis and CART model in order to clarify the relationship between the factors of oral health management habits that contribute to toothache occurrence. According to the result, there was a difference between the present health status and the health status of the past year depending on the presence or non-presence of toothache occurrence (p<0.05). There was a difference in the regularity of meal time depending on the presence non-presence of toothache occurrence from the dietary habits of the research subjects (p<0.05). As for the presence or non-presence of toothache occurrence from the oral hygiene habits of the research subject, there was a difference between the occurrence and nonoccurrence of bleeding during brushing or flossing (p<0.05). According to the results of regression analysis, no factors were signifiant in the relationship with the presence or non-presence of toothache occurrence from the status of life habits and oral hygiene habits. 70% of the researched group was randomly selected as the sample for generating an analytical model and the remaining 30% was used as the sample for generating an evaluation model. According to the results of CART model, the occurrence of toothache was higher in the case of irregular meal time and poor current health condition than the case of average or satisfactory health condition. The above results imply that CART model is very useful technique in predicting toothache occurrence compared to regression analysis, and suggests that CART model could be very useful in predicting other oral diseases including toothache.

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