• Korean Journal of Psychosomatic Medicine
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• v.5 no.2
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• pp.176-184
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• 1997

Abnormal illness behavior in patients with somatoform disorders were known formed by their traditional disease concepts and somatization-prone socio-cultural factors. The authors evaluated the characteristics of abnormal illness behavior in patients with somatoform disorders(who had somatization) by using abnormal illness behavior questionnaire. Methods : 29 somatoform disorders(SD) and 57 disease controls were compared by clinical characteristics, severity of pain, state anxiety(by Spielberger's State & Trait Anxiety Inventory), depression(by Beck's Depression Inventory) and level of psychosocial stess(by DSM-III-R). The illness behavior was measured by illness Behavior Questionnaire(IBQ). Results SD group had longer period of somatic symptoms with less severity in pain. The degree of anxiety and depression were higher in SB compared with controls. However, the degree of psychosocial stress was almost same between both groups. In IBQ, SD showed higher scores in general hypochondriasis, disease conviction, and affective disturbance subscales compared to control group. Conclusion: High disease conviction and hypochondriacal nature revealed by IBQ seemed to be a role in making somatization by way of somatic focusing and hypervigilance. And those tended to lead patients visit hospital frequently and report various somatic complaints. Evaluating abnormal illness behavior in somatoform disorders would be not only helpful in understanding the natures of somatoform disorders but also useful differentiating SD with other psychiatric conditions.

• Journal of Life Science
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• v.28 no.11
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• pp.1379-1385
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• 2018

Glycans are attached to proteins as in glycoproteins and proteoglycans. They are found on the exterior surface of cells. O- and N-linked glycans are very common in eukaryotic cells but may also be found in prokaryotes. The interaction of cell surface glycans with complementary glycan binding proteins located on neighboring cells, other cell types, pathogens like virus, or bacteria is crucial in biologically and biomedically important processes like pathogen recognition, cell migration, cell-cell adhesion, development, and infection. Their implication in pathological condition, suggests an important role for glycans as disease markers. In addition, a great amount of research has been shown that appropriate glycosylation of a recombinant therapeutic protein is critical for product solubility, stability, pharmacokinetics and pharmacodynamics, bioactivity, and safety. Besides, cancer-associated glycosylation changes often involve sialic acid in glycan branch which play important roles in cell-cell interaction, recognition and immunological response. This review aims at giving a comprehensive overview of the glycan's biological function and describing the relevance among the glycosylation, disease diagnosis and treatment methods. Furthermore, the high-throughput analytic methods available to measure the profile changing patterns of glycan in the blood serum as well as possible underlying biochemical mechanisms.

• Bioinformatics and Biosystems
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• v.2 no.2
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• pp.66-70
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• 2007

과거 사회라는 개념 속에서의 관찰과 통계적 인과관계의 규명에 치중하여 이루어졌던 보건학 연구는 유전체 연구와 같은 증거 위주의 기초과학적 측면에서 이루어 지고 있는 것이 현재의 추세이다. 이러한 생물학적 데이터를 이용한 질병과 보건에 대한 연구가 활성화 됨에 따라 보건 분야에서도 컴퓨터를 이용하여 방대한 정보를 다룰 수 있는 생명정보학이 유용한 도구로서 인식되고 있다. 본고에서는 생명정보학이 보건학의 연구분야에서 어떻게 이용되는 가를 학술적인 의미에서 살펴보고 그 활용방안에 대해 논의해 보고자 한다.

• 방재와보험
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• s.119
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• pp.60-65
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• 2007

흔히 문화는 상징이라 한다. 상징이란 무엇일까? 사전의 정의를 빌리자면 '추상적인 개념이나 사물을 구체적인 사물이나 표지 또는 기호로 나타낸 것' 이 상징이다. 바꿔 말하면 드러내고자 하는 것을 다른 것으로 바궈서 보여준다는 것이다. 물로 보여주는 대상이 인간 존재일 수도 있지만 민속문화에서는 인간의 삶을 위협하는 비인간적인 존재이기 일쑤다. 예컨대 삿된 것은 말할 것도 없고, 사악한 것들, 질병을 옮겨 준다는 역귀들까지 그 대상이 된다. 이들은 비인간적 존재이면서 우리를 해코지하는 비정상적인 존재이기 때문에 두려움과 회피의 대상이다. 상징을 통해 이들 존재를 피하고자 하는 것은 당연한 일이 아닐 수 없다.

• The Monthly Diabetes
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• s.239
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• pp.50-52
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• 2009

그 동안 당뇨병은 완치할 수 있는 병이 아닌 관리차원의 질병이라는 개념으로 인식되어져 왔다. 많은 환자들이 검증되지 않은 민간요법이나 그릇된 방법을 써서라도 당뇨병을 치료하고자 한다. 그만큼 당뇨병환자의 마음이 절실하기 때문인데 이러한 사실을 반영이라도 한 듯 최근에는 다양한 치료법이 개발되고 있다. 그 가운데 얼마 전 수술을 통해 당뇨병을 치료했다는 희소식에 많은 관심이 집중되고 있다. 그 선두에 있는 인하대병원 허윤석(일반외과) 교수를 만나�R다.

• THE HEALTH and ORGANIC FARMING
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• no.182
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• pp.1-24
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• 2002

사상 유례없는 태풍 '루사' 피해복구에 총력을!!/지구의 미래는 유기농업뿐이다!/헤어리벳치 실증재배기술 요약/내년 농업예산 삭감.축소편성 '파장'/아주 편리한 신개념 고추건조방법이란?/전국 친환경농업 품평.전시회/GMO (유전자변형식품) 이란무엇인가?/유기농업에의한 양계/9월중 농사정보/당신도 무병장수를 꿈꾸는가?/후사리움균(Fusarium)병의 방제법/영국의 유기농업 농가의 소득손실?/미생물의 질병방제 기작/영천시 유기농업 한마음대회 성료

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.1
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• pp.145-155
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• 2010

In this paper, we suggest a fish drug domain ontology to show an associated information and hierarchy together through concept-relation and inference mechanism instead of keyword matching. First, we investigate competency questions from workers of fishery industry and then we derive concepts and terminologies. Next, we present a process of fish drug ontology modelling using Protege-OWL editor, which is an extension of Protege that supports the Web Ontology Language(OWL). Last, we suggest the user interface of semantic web-based fish drug information system to search easily associated informations of fish drug using this ontology. It is to provide an effective search method that fish disease manager, fish farmer, and students majoring in fisheries can confirm details of diseases, fish, and drug evaluations associated with fish drug within one screen without moving to another position.

• Journal of Korean Academy of Nursing
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• v.22 no.2
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• pp.143-156
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• 1992

This descriptive study explored the health and illness concepts of preschoolers to provide understanding on which to build research. The subjects were convenience sample three to six year of age attending one art institute in Cheju city. Data were collected through semistructured interviews by author, Children were asked to draw two figures, one healthy and one ill persons. The drawings were not analysed to grasp the meaning as in a projective technique, but only to relate to their response. Data were coded and categorized by content analysis. The results of this study are summarized as follows : 1) Three year olds responded with some unrelated answers but well to questions related to their experiences of illness ; older participants answered questions related health and illness concepts more easily. Generally the levels of subjects' responses did not differ according to age and sex. 2) Preschoolers' answers about the cause, treatment and prevention of illness, and the meaning and promotion of health were coded and then classificated to 9 categories, (food, obedience to authoritys physical function, presence or absence of illness or symptoms, hygiene. treatment, traumatic injury, rest and germs). Food and obeidence to authority categories were most frequent responses the food category was associated with obeidence to authority because it seemed that the children follow the orders of their parents or other authority figures to eat or not to eat something This result was compatible with that of previous studies that preschoolers perceived illness as possible punishment for misbehavior. Participants except for one four year old boy did not suggest that germs cause illness. The children perceived themselves and their families as healthy even though they had symptoms of illness. 3) Preschoolers' health and illness concepts were. influenced by their experiences and related to their development that rules derived from authority and if not complied with, will bring punishment. These oonceptualizations may be the disparity that they perceived themselves and their families as healthy even though they were ill. A previous study by Perrin and Gerrity suggested that the level of children's illness concepts correlated with that of their physical causality and was lower than it. But the levels of health and illness concepts in this sample higher than those of the physical causality.

• Journal of the korean veterinary medical association
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• v.38 no.4
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• pp.376-382
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• 2002

호주의 많은 소동물 임상수의사들이 최근에 관심을 갖고 있는 부분은 개의 아토피(Canine Atopy)에서의 알러지-특이성(Allergen-specific)IgE에 쓰이는 혈청 ELISA (Enzyme-Linked Immuno-Sorbent Assay, 효소결합면역흡착검사)테스트의 활용 가능성에 관한 것이다. 희망사항은 개 아토피의 진단과 치료에 있어서 도움이 되도록 접근할 수 있는 시험(Accessible test)일 것이다. 아토피(Atopy)는 진단과 치료를 실패시키는 질병이며, 새로운 ELISA라도 이 문제를 쉽게 해결하여 주지 못한다. 개의 아토피에서 알려진(Allergens)들을 분석하는 데 쓰이는 혈청 ELISA처럼 아주 정확하게 특성화되어져야 한다. 해당 개는 아토피성(Atopic)으로서 진단되어져야만 되고 그 다음에 치료에 지침이 되도록 개별 알러진 동정(Individual allergen identification)용 ELISA로 개의 혈액을 스크린하는데 적합하여야 한다. ELISA와 피내접종시험(Internal testing)방법은 상관도가 낮고 그렇기 때문에 어떤 시험이 더 신뢰할 수 있는 것일까? 이러한 사실은 논쟁의 여지가 있으며 이상의 2가지 시험들이 옳다면 각각의 상응하는 각각 다른 아형(Subtypes)의 아토피라고 볼 수있다. 아마도 알러진들은 경피적으로 흡수되어 아토피성피부염으로 되어진다. 그것은 인체에서 건초열(Hay fever)이나 천식(Asthma)과 같이 흡입에 의해 일으키는 유사한 증후군동종 (Syndrome akin)과 같은 접근의 초기양식(Primary mode of access)으로부터 생기는 다른 유사한 질병과정이 되어질 수도 있다. 이러한 2가지 증후군은 함께 병발하는 경우가 있다. 의학에서는 피부 반점시험방법의 예비조사연구(Preliminary research with skin patch testing in medicine)는 아토피성 피부염을 야기하는 알러진들의 경피흡수경로의 개념을 지지해준다. 흡인 알러진들을 사용한 개들에서의 도전 시험(Challenge tests)들은 거의 대부분이 비-피부학적 임상증상들을 발현하였다. 모든 증거가 분명히 나타나도록 미래의 조사연구를 인도해 주는 게 필요하며 개 아토피의 정의와 진단을 둘러싼 수수께끼를 해결하는데 도움이 될 것이다.

• Child Health Nursing Research
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• v.7 no.1
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• pp.5-20
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• 2001

The purpose of this study was to analyze and identify the higher-grade primary school children's needs for sexual education. We got the data with open question from 481 children from March to July 1999. We analyzed them according to the framework suggested by the Sex Information and Education Council of USA. The framework involves the six domains such as human development, relationship, personal skills, sexual behavior, sexual health, and society & culture. In the analysis of need for sexual education according to domain, need for human development was highest (79.2 ％), after that followed society & culture (8.3 ％), sexual health (5.8％), sexual behavior (3.6％), and relationships (3.1％). There was no need for personal skills. By topics, there were needs for puberty (38.0％), reproduction (32.5％), gender roles (6.0％), body image (4.9％), sexual abuse (2.4％) and reproductive health (2.4％). Girls and boys all mostly wanted to know human development 41.0 ％ and 38.2 ％ each. Society & culture (3.4 ％), sexual behaviour (2.7％), sexual health (2.6％), relationship (2.4％) were domains selected by boys. Girls wanted to know society & culture (4.9％) and 'sexual health (3.2％). Comparing by grade, fourth, fifth and sixth grade children are commonly interested in development, society & culture. Fourth grade children scarcely show attention on the relationship, sexual behaviour and sexual health; meanwhile sixth grade children would like to know sexual behaviour and sexual health. When their grade became higher, they would like to know more precise, concrete and deep information. We suggest that the textbook/guidebook for sexual health for the higher-grade primary school children should be developed considering the sex and grade.