• The Korean Journal of Pharmacology
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• v.30 no.3
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• pp.321-330
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• 1994

The protective effect of 'ischemic preconditioning (PC)' on ischemia-reperfusion injury of heart has been reported in various animal species, but without known mechanisms in detail. In an attempt to investigate the cardioprotective mechanism of PC, we examined the effects of PC on the myocardial oxidative injuries and the oxygen free radical production in the ischemia-reperfusion model of isolated Langendorff preparations of rat hearts. PC was performed with three episodes of 5 min ischemia and 5 min reperfusion before the induction of prolonged ischemia (30 min)-reperfusion(20 min). PC prevented the depression of cardiac function (left ventricular pressure x heart rate) observed in the ischemic-reperfused heart, and reduced the release of lactate dehydrogenase during the reperfusion period. On electron microscopic pictures, myocardial ultrastructures were relatively well preserved in PC hearts as compared with non-PC ischemic-reperfused hearts. In PC hearts, lipid peroxidation of myocardial tissue as estimated from malondialdehyde production was markedly reduced. PC did not affect the activity of xanthine oxidase which is a major source of oxygen radicals in the ischemic rat hearts, but the myocardial content of hypoxanthine (a substrate for xanthine oxidase) was much lower in PC hearts. It is suggested from these results that PC brings about significant myocardial protection in ischemic-reperfused heart and this effect may be related to the suppression of oxygen free radical reactions.

• Journal of the Korean Geotechnical Society
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• v.30 no.6
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• pp.23-39
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• 2014

An artificial rainwater reservoir installed in urban areas for recycling rainwater is an eco-friendly facility for reducing storm water effluence. However, in order to recycle the rainwater directly, the artificial rainwater reservoir requires an auxiliary system that can remove non-point source pollutants included in the initial rainfall of urban area. Therefore, the conventional soil filtration technology is adopted to capture non-point source pollutants in an economical and efficient way in the purification system of artificial rainwater reservoirs. In order to satisfy such a demand, clogging characteristics of the sand filter layers with different grain-size distributions were studied with real non-point source pollutants. For this, a series of lab-scale chamber tests were conducted to make a prediction model for removal of non-point source pollutants, based on the clogging theory. The laboratory chamber experiments were carried out by permeating two types of artificially contaminated water through five different types of sand filter layers with different grain-size distributions. The two artificial contaminated waters were made by fine marine-clay particles and real non-point source pollutants collected from motorcar roads of Seoul, Korea. In the laboratory chamber experiments, the concentrations of the artificial contaminated water were measured in terms of TSS (Total Suspended Solids) and COD (Chemical Oxygen Demand) and compared with each other to evaluate the performance of sand filter layers. In addition, the accumulated weight of pollutant particles clogged in the sand filter layers was estimated. This paper suggests a prediction model for removal of non-point source pollutants with theoretical consideration of the physical characteristics such as the grain-size distribution and composition, and change in the hydraulic conductivity and porosity of sand filter layers. The lumped parameter ${\theta}$ related with the clogging property was estimated by comparing the accumulated weight of pollutant particles obtained from the laboratory chamber experiments and calculated from the prediction model based on the clogging theory. It is found that the lumped parameter ${\theta}$ has a significant influence on the amount of the pollutant particles clogged in the pores of sand filter layers. In conclusion, according to the clogging prediction model, a double-sand-filter layer consisting of two separate layers: the upper sand-filter layer with the effective particle size of 1.49 mm and the lower sand-filter layer with the effective particle size of 0.93 mm, is proposed as the optimum system for removing non-point source pollutants in the field-sized artificial rainwater reservoir.

• Proceedings of the Korea Water Resources Association Conference
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• 2007.05a
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• pp.361-365
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• 2007

자연재난은 발생원인에 따라 바람, 강우, 적설, 파고등으로 구분할 수 있다. 이러한 재난원인은 자연현상의 일부로 발생하였으나, 경제가 발전함에 따라 과거에 비해 재해에 안전한 사회를 요구하게 되어 재해저감을 위한 투자와 방재정책 개발의 필요성이 증대되고 있다. 기존에는 자연재난을 저감시키기 위하여 연최대치 강우를 통계 분석하고 강우-유출관계를 이용하여 장래에 발생할 홍수량을 예측하여 자연재난을 저감할 수 있도록 설계하는 것이 일반적인 재난저감계획 수립으로 간주되었다. 그러나, 재해예방을 위해서는 과거에 발생한 재난의 지역적 특성을 분석하여 재난발생 위험과 피해규모를 파악함으로써 재난계획 수립의 기초자료로 활용할 필요성이 있다. 이러한 자연재난에 대한 대책수립은 국가차원에서 필요하며 이를 위해서는 지역별 안전도 평가의 필요성이 증가하게 된다. 그러나 이러한 연구를 수행하기 위해서는 방대한 자료를 바탕으로 풍수해 발생특성을 분석하는 연구와 지자체 또는 지역별 재난피해저감 능력을 수치적으로 나타낼 필요성이 있다. 따라서, 공학적인 면뿐만 아니라 행정적인 면을 동시에 고려하는 학제간 연구가 필요하다. 본 연구에서는 우리나라에서 주로 발생하는 풍수해에 의한 자연재난 특성을 파악하고 재난발생 확률을 고려한 재난피해규모와 재난피해 저감능력을 비교하여 전국 234개 지자체별 지역 및 시설물별 안전도를 평가하고자 한다. 과거 10년간 재해연보에 수록된 지자체별 피해현황을 지자체별 특성을 고려하여 분석, 지자체별 연평균 피해규모를 소방방재청의 지역별 안전도 지침서에 의거, 10등급으로 분석하였다. 또한, 지자체별로 투자우선순위 및 방재예산편성의 효율성 극대화를 위해 지자체별 시설물별 피해현황을 분석하는 기법을 개발하여 지자체별 시설물별 안전도 진단지표를 설정하였다. 분석된 결과는 지자체별 시설물별 재해저감을 위한 풍수해저감 종합계획 재난보험제도 도입등의 기초자료로 적용될 수 있다.로 나타났다. 이는 두 흐름에 의해 와(vortex)가 크게 형성되어 하상의 세굴에 영향을 미치기 때문으로 판단되었다.보다 본질부가 차지하는 면적이 월등히 적고 제1차 및 제2차섬유가 차지하는 면적이 많았다. 따라서 고섬유함량인 대마의 품종개량에 있어서는 가능한 한 본질부가 차지하는 면적은 축소시키고 제1차 및 제2차섬유가 차지하는 면적은 증대시켜야 할 것으로 본다.우리 나라 수도의 작기는 앞으로 당기는 것이 좋다고 고찰된다. 6. 우리 나라의 현행 수도작기로 본 기온 및 일조조건은 수도의 분얼전기에 대해서는 호조건하에 놓여 있으나, 분얼후기인 7월 중ㆍ하순 경의 일조부족과 고온다습조건은 병해, 특히 도열병의 유발원인이 되고 있다. 7. 우리 나라의 현행수도작기로 본 전국각지의 수도의 출수기는 모두 일조시간이 적은 부적당한 시기에 처해 있다. 8. 출수후 40일간의 평균기온에 의한 적산온도 88$0^{\circ}C$의 출현기일은 수원에서 8월 23일이었고, 년간편차를 고려한 안전출수기일은 8월 19일로서 적산온도면에서는 관행 출수기일은 약간 늦다고 보았다. 9. 등열기의 평균기온에 의한 적산온도는 현행 수도작기로서는 최종한계시기에 놓여 있으며, 평균기온의 년간편차와 우리 나라의 최저기온이 낮은 점을 고려할 때, 현행출수기는 다소 늦은 것으로 보았다. 10. 생육단계별의 수도체내의 질소함량은 영양생장기의 질소함량이 과다하였으며, 출수 이후에 영양조락을 여하히 방지하느냐가 문제된다고 보았다. 11. 수리불안전답 및 천수답이 차지하는 전답면적의 비율은 차차 감소되고 있는데, 이와 전체 10a당 수량의 증가율과의 상관계수를 산출하였는데, 수리불안전답과의 상관계수 (4)는 +0.525였으며, 천수답과는 r=+0.832, 그리고 수리불안전답과 천수답을 합계한 것과의 상관계수 (r)는 +0.841로서 후2자와는 고도의 정(+) 상관을 보여 천수답이 차지하는 면적비율이 작

• Korean Journal of Plant Resources
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• v.33 no.1
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• pp.15-23
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• 2020

There is high vulnerability of soil loss in sloping and highland used for agricultural production due to the low surface covering in summer rainy season. This study evaluated the surface-covering rate of landscape crop in reducing soil loss in the highland. The experiment was conducted in a 55% sloped lysimeter with three treatments of planting density using Korean native chrysanthemum, and investigated the soil coverage rate, run-off water, and soil erosion. The three treatments according to the degree of soil covering are bare soil as the control treatment TC, coverage rate of 43-59% for treatment T1, and, coverage rate of 63-81% for treatment T1, and T2. During the cultivation period, the average reduction of run-off water was 71% for treatment T1 and 76% for treatment T2, which are better, compared with the control. The reduction in eroded soil was 84% in treatment T1 and 98% for treatment T2, which is also better than the control treatment. Therefore, it is possible to alleviate the soil loss in sloping lands by planting chrysanthemum, which is superior among the perennial plant species and considered as a crop with economic value.

• Journal of the Korean Society of Safety
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• v.7 no.2
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• pp.63-70
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• 1992

The aim of this research is to obtain a basic quantitative understanding of the effect of a noncondensable gas on the absorption of water vapor by a $H_2O$ / LiBr combination with n-octanol as the surfactant. Nonflowing aqueous solutions of LiBr (40,45,50 mass％) were exposed to saturated water vapor following the addition of an n-octanol sufactant (0.01 and 0.6 mass％). A small amount of a noncondensable gas (air) was allowed into the absorber (0.03 volume％) and its effect was analyzed by measuring the amount of water vapor absorbed. This study will aid to predict the performance of heat pump and safety operating condition when the noncondensable gas is not allowed in the absorber The results indicate that, in the presence of small amounts of a noncondensable gas, vapor absorption enhancement ratios are less than half o( those obtained under the same experimental conditions when a noncondensable gas is not present (1). The presence of a noncondensable gas causes the partial vapor pressure of air to increase at the vapor / liquid interface, which results in an instability of vapor absorption rate nd. hence, in an inhibition of interfacial disturbance.

• Journal of Nutrition and Health
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• v.41 no.5
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• pp.381-390
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• 2008

Present study was conducted to investigate the effects of exercise and cholesterol diet on plasma and liver lipids, platelet aggregation, erythrocyte Na efflux and liver index such as GOT and GPT using Sprague Dawley rats. Forty rats were divided into four groups and fed control or 0.5% cholesterol diet with and without treadmill for six weeks. The final body weight of group fed cholesterol diet with exercise was somewhat decreased compared with group fed cholesterol diet without exercise. L.W/B.W ratio was significantly increased in groups fed cholesterol diet (p < 0.01), but exercise tended to decrease this ratio. Plasma total cholesterol was significantly increased and HDL-cholesterol was decreased in groups fed cholesterol diet (p < 0.01). Plasma triglyceride was significantly decreased in groups fed cholesterol diet compared with groups fed control diet (p < 0.01). Plasma triglyceride of groups with exercise was significantly decreased compared with their non exercising counterparts regardless diet (p < 0.05). Liver total cholesterol and triglyceride was significantly increased in groups fed cholesterol diet (p < 0.01), but exercise did not affect on these levels. Na-K ATPase was somewhat decreased in groups fed cholesterol diet, and exercise tended to recover the reduced Na-K ATPase. Na passive transport was significantly decreased in group fed control diet without exercise and significantly increased in group fed cholesterol diet with exercise, there were significant differences between groups (p < 0.05). There were no differences in total Na efflux and intracellular Na among groups, and total Na efflux was not correlated with intracellular Na. Hematocrit was significantly lower (p < 0.05) in group fed cholesterol diet without exercise compared with other groups. Platelet aggregation in the initial slope and the maximum was increased in groups fed cholesterol diet, but not statistically significant. Exercise especially increased the initial slope of aggregation. Plasma GOT and GPT was significantly increased in groups fed cholesterol diet (p < 0.01), and exercise in group fed cholesterol diet significantly decreased both GOT and GPT compared with the non exercising counterpart (p < 0.01). This study showed that cholesterol diet increases plasma and liver lipids and GOT and GPT, and exercise improves plasma and liver lipid profile and liver index of GOT and GPT preventing fatty liver.

• Ecology and Resilient Infrastructure
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• v.7 no.4
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• pp.262-273
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• 2020

Amending biopolymers such as β-glucan (BG) and Xanthan gum (XG) generally enhances soil strength by ionic and hydrogen bonds between soil particles. Thus, biopolymers have been studied as eco-friendly construction materials in levees. However, physiological responses of plants grown on soil amended with biopolymers are not fully understood. This study focuses on the effects of biopolymers on the growth of Camelina sativa L. (Camelina) under excess zinc (Zn) stress. The optimal concentrations of BG and XG were confirmed to have a 0.5% ratio in soil depending on the physiological parameters of Camelina under excess Zn stress. The Zn binding capacity of biopolymers was investigated using 1,5-diphenylthiocarbazone (DTZ). The reduction of Zn damage in Camelina was evaluated by analyzing the Zn content and expression of heavy metal ATPase (HMA) genes under excess Zn stress. Amendments of BG and XG improved Camelina growth under excess Zn stress. In DTZ staining and ICP-OES analysis, Camelina grown on BG and XG soil showed less Zn uptake than normal soil under excess Zn stress. The Zn-inducible CsHMA3 gene was not stimulated by either BG or XG amendment under excess Zn stress. Moreover, both BG and XG amendments in soil exhibit Zn-stress mitigation similar to that of Zn-tolerant CsHMA3 overexpres sed Camelina. These results indicate that biopolymer-amended soils may influence the prevention of Zn absorption in Camelina under excess Zn stress. Thus, BG and XG are proven to be suitable materials for levee construction and can protect plants from soil contamination by Zn.