• Proceedings of the Korean Society of Life Science Conference
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• 2003.05a
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• pp.80-80
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• 2003

• YAKHAK HOEJI
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• v.15 no.2
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• pp.64-75
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• 1971

Optimum condition for cultivation of Anemarrhena asphodeloides B$_{UNGE}$ and seasonal variation of saponin and sapogenin contents in the rhizome were investigated. It is confirmed that the best harvest time is 3rd year. Average contents of saponin in rhizome was 8.5% and 5.0%, in fibrous roots, being highest in winter. The facotrs of saponin content variation were seemed to be temperature and humidity. It was also proved that asphonin was the mixture of timosaponin A-III, timosaponin A-I and mangiferin. Mangiferin and isomangiferin were isolated from the flower.

• Proceedings of the Korean Society of Life Science Conference
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• 2003.10a
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• pp.91-91
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• 2003

• 한국약용작물학회:학술대회논문집
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• 2008.05a
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• pp.67-68
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• 2008

• Korean Journal of Plant Resources
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• v.10 no.2
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• pp.183-187
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• 1997

This study was carried out to find the growth characteristics and content of sarsasapogenin in different plant parts of Anemarrhena asphodeloides Bunge. Five native-cultivars were collected and evaluated for several agronomic traits. The collected native-cultivars were classified into two seed-attached peduncle and vegetative propagation types. Seed-attached peduncle lines were predominance of growth traits than vegetative propagation. For the content of sarsasapogenin in each part was investigated, BuOH extarct of 'timo' was developed on silica gel 60G plate using elution solvent($CHC1_2$: Methyl ethyl Ketone : EtOH = 11 : 2 : 0.5). The developed plate were examined using Dual Wavelength Zig - Zag using. Content of sarsasapogenin in main root and lateral root were respectively 1.67mg/g and 1.31mg/g.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.36 no.1
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• pp.37-45
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• 2012

This study investigates the pressure leakage characteristics of a desiccant rotor with a brush-type air seal. Through a pressure leakage experiment, a correlation equation for the leakage air flow rate is obtained as a function of the air seal area and pressure difference. Using this equation, an air leakage model for the desiccant rotor is developed. By comparing simulation results with the experimental results for the desiccant rotor, the accuracy of the air leakage model is demonstrated. A performance test of a desiccant rotor with various air flow rates is carried out. Using the air leakage model, the effective mass flow rate and air leakage rate are found. In addition, the characteristics of the air leakage are analyzed for a desiccant cooling system using the developed air leakage model.

• Journal of Life Science
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• v.28 no.3
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• pp.307-313
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• 2018

Alopecia cause psychological stress due to their effect on appearance. Thus, the global market size of the alopecia treatment products are growing quickly. Timosaponin A III is the well known active ingredient of Anemarrhenae Rhizoma. In this study, we investigated and compared the binding affinity of timosaponin A III with finasteride (5-beta reductase antagonist) and minoxidil (androgen receptor antagonist) on the target protein active site by in silico computational docking studies. The three dimensional crystallographic structure of 5-beta reductase (PDB ID : 3G1R) and androgen receptor (PDB ID: 4K7A) was obtained from PDB database. In silico computational autodocking analysis was performed using PyRx, Autodock Vina, Discovery Studio Version 4.5, and NX-QuickPharm option based on scoring functions. The timosaponin A III showed optimum binding affinity (docking energy) with 5-beta reductase as -12.20 kcal/mol as compared to the finasteride (-11.70 kcal/mol) and with androgen receptor as -9.00 kcal/mol as compared to the minoxidil (-7.40 kcal/mol). The centroid X, Y, Z grid position of the timosaponin A III on the 5-beta reductase was similar (overlap) to the finasteride, but the X, Y, Z centroid grid of the timosaponin A III on the androgen receptor was significantly far from the minoxidil centroid position. These results significantly indicated that timosaponin A III could be more potent antagonist to the 5-beta reductase and androgen receptor. Therefore, the extract of Anemarrhenae Rhizoma or timosaponin A III containing biomaterials can substitute the finasteride and minoxidil and can be applied to the alopecia protecting product and related industrial fields.

• 한국공간정보시스템학회:학술대회논문집
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• 2005.05a
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• pp.355-361
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• 2005

3차원 자료의 필요에 발맞추어 3차원 좌표를 직접적으로 획득할 수 있는 LIDAR 시스템이 등장하게 되었다 항공 LIDAR 시스템은 항공기, GPS, INS, Laser Scanner가 통합된 시스템으로 항공기에서 발사된 Laser의 반사파를 이용하여 거리와 그 때의 항공기의 자세, 위치를 통합하여 직접적인 3차원 포인트 자료를 획득할 수 있다. LiDAR 데이터는 지형, 건물, 식생 등의 지면위에 있는 모든 객체에 대한 3차원 자료와 영상자료를 함께 제공하고 있다. 이러한 LIDAR 자료로부터 DEM, DTM 등의 지형 정보와 식목, 건물 등 지물정보를 추출하는 연구가 활발하게 이루어지고 있다. 본 연구에서는 지형을 추출하는데 사용할 수 있는 몇 가지 필터링기법을 선정하여 국내의 다양한 지모, 지물에 적용하고 그 정확도를 평가해 보았다.

• 한국생물공학회:학술대회논문집
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• 2000.04a
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• pp.247-250
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• 2000

Extracellular polysaccharide was produced by Pseudomonas elodea ATCC 31461 under aerobic condition. Nitrogen sources in medium affected cell growth and production of exopolymer. Ammonium nitrate limitation was found to be essential for higher production of exopolymer. Conversion rate of exopolymer from glucose under ammonium nitrate limitation was about 5 times higher than with ammonium nitrate.

• The Korea Journal of Herbology
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• v.22 no.3
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• pp.101-107
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• 2007

Objective : This study was carried out to investigate diagnostic difference and anti-oxidative effect of 3 different Anemarrhenae Rhizoma (AR) extracts. Methods : Microscopic examination was used to distinguish histological differences. And eliminative ability of several kinds of free radicals was also measured. Results : In microscopic examination, we can distinguished three different lineage of AR with different structure of vascular bundles and secretory structures. The extract of AR show profitable abilities of elimination of DPPH free radical, ABTS free radical and hydrogen peroxide. Conclusion : So, it can be concluded that AR extract has an anti-oxidative effects. Especially indeciduous lineage was most effective to remove free radicals.