• Korean Journal of Psychosomatic Medicine
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• v.27 no.2
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• pp.85-89
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• 2019

Objectives : The purpose of this study was to quantitatively assess the degree of myasthenia gravis (MG) affecting mental health through the results of multiphasic military personality inventory in late adolescence. Methods : We collected and analyzed the results of the military personality inventory for healthy controls and MG patients among the 19-year-old men who visited the Military Manpower Administration from February 2007 to January 2010. Military personality inventory invented for Korean military test has similar system to Minnesota multiphasic personality inventory. Results : Among validity scales, each score of faking good, faking bad and infrequency subscales showed no difference between healthy control and MG groups, respectively (t=-0.51, p=0.607 ; t=0.11, p=0.913 ; t=1.41, p=0.158). Among neurosis scales, the score of somatization subscale was higher (t=2.29, p=0.023) in MG group. Among psychopath scales, the score of schizophrenia subscale was lower in MG group (t=-2.38, p=0.018). Conclusions : According to MPI results, we can confirm that MG patients in late adolescence may be more concerned with their somatic symptoms than the control group, and that they may be more likely to abide by the regulation and be conventional in their behavior than the control group.

• Proceedings of the Korean Society of Health Policy and Administration Conference
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• 2004.05a
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• pp.89-104
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• 2004

최근 들어 국가질병관리체계 현대화가 세계 각국 정부의 중요한 과제가 되고 있다. 캐나다 연방정부는 감염병과 만성질환을 관리하고 생물테러 등 응급상황에 효과적으로 대처하기 위하여 새로운 질병관리조직인 Public Health Agency를 창설하기로 결정하였다. 연방정부는 앞으로 2년간 1,412억원을 투입하여 Agency를 설립하고 사업기반을 확충해 나갈 예정이다(Health Canada, 2004). 또 EU 집행위원회도 지난 3월 European Center for Disease Prevention and Control 설립계획을 최종 승인하고 ECDC가 발족하는 내년 한 해에만 71억원을 투입할 예정이다(Bosch, 2004). 이렇듯 새로운 질병관리조직들이 만들어지고 있는 직접적인 계기는, 중증급성호흡기증후군(이하 SARS) 사태로 대변되는 신종 및 재출현 전염병의 폭발적 발생(outbreak)이다. 전염병의 만연 사태가 일어나면서 각국 정부는 국민건강 보호의 중요성을 재확인하는 한편, 질병으로 인한 경제적 손실을 현실적 문제로 인식하게 되었다. 비전염성질환과 손상으로 인한 질병부담도 세계 각국의 골칫거리다. 서구 여러 나라에서는 비전염성질환과 손상의 질병부담이 이미 매우 큰 상태이며, 저개발 국가들은 전염병과 비전염성질환으로 인한 "이중의 질병부담(double burden of disease)"을 안고 있다고 한다. (중략)고 한다. (중략)

• The Optical Journal
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• s.156
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• pp.41-51
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• 2015

생명공학기술(BT)과 정보통신기술(IT)의 융합으로 모바일 의료기기가 최근 빠른 속도로 발전 하고 있다. 작년부터 시작된 헬스케어 웨어러블 디바이스의 열풍은 IT기업의 헬스케어 시장 진입을 촉진하고 있으며, 스마트폰의 보급으로 인해 의료기기의 활용도와 편리성이 비약적으로 향상되고 있다. 각각의 영역에서 발전하던 의료기기와 스마트기기는 이제 모바일 의료기기라는 하나의 시장에서 만난다. 의료진을 중심으로 개발되던 의료기기는 소비자의 관점에서 재조명되어 보다 유용한 기기로 탈바꿈하고 있다. 단순한 건강관리에서부터 중증질환의 치료에 이르기까지 모바일 의료기기가 제공하는 스마트 헬스케어 솔루션이 중요한 역할을 할 것으로 기대된다. 본 보고서는 최근의 바이오 기술과 헬스케어 스마트기기의 발달을 살펴보고, 모바일 의료기기가 가져올 스마트 헬스케어의 가능성과 극복해야 할 장애물에 대해 분석하였다. 특히 ICT 융합산업이 직면하게 되는 이종 산업의 속성 차이를 이해하는데 주안점을 두었다.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.296-296
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• 1994

수술시 근육 이완제로 사용되고 있는 metocurine iodide는 항생물질 투여환자, 중증 근무력중, 전해질 평형실조, 중증 신질환이 있는 환자 등에서는 작용이 증가되어서 상용량에서도 약화사고의 우려가 있어 규제가 필요한 약물이다. Metocurine iodide를 생체 시료중에서 분석하기 위해 rosebengal과 착제를 형성시켜 유기용매로 이온쌍 추출을 한 후, HPLC를 이용하여 rose bengal율 분석함으로써 metocurine iodide를 간접 정량하는 방법을 확립하였다. 이 방법은 뇨와 혈액증에 함유된 metocurine iodide를 0.09 - 9.10$\mu\textrm{g}$/m1농도에서 분석할 수 있었으며, 상관계수는 0.994 - 0.999로 양호한 직선성을 나타내었고, 동시 처방 약물의 영향은 거의 없었다. 뇨 및 혈액중 metocurine iodide의 검출 한계는 각각 0.8ng. 1.2ng (S =3)이었다.

• Journal of the Korean Society of Radiology
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• v.82 no.4
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• pp.808-816
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• 2021

Pulmonary emphysema is a cause of chronic obstructive pulmonary disease. Emphysema can be accurately diagnosed via CT. The severity of emphysema can be assessed using visual interpretation or quantitative analysis. Various studies on emphysema using deep learning have also been conducted. Although the classification of emphysema has proven clinically useful, there is a need to improve the reliability of the measurement.

• Sleep Medicine and Psychophysiology
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• v.27 no.2
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• pp.77-81
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• 2020

Obstructive sleep apnea (OSA) is a sleep-related breathing disorder in which narrowing and obstruction of the upper airway lead to frequent arousal and decreased arterial oxygenation during sleep. OSA is more common in children with genetic disorders like achondroplasia compared to children without genetic disorders. Achondroplasia is genetic disorder characterized by hypoplasia of the facial bone and skull base with foramen magnum stenosis, resulting in exceedingly high frequency of OSA. The authors present a case of a patient with achondroplasia diagnosed with severe OSA through polysomnography after adenectomy showed little therapeutic effect and who was treated with continuous positive airway pressure.

• Proceedings of the Korea Information Processing Society Conference
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• 2019.10a
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• pp.1080-1081
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• 2019

만성간질환의 조기 발견과 적절한 관리는 중증 질환으로 진행을 차단하거나 완치하는데 큰 역할을 할 수 있다. 만성간질환을 진단하는 Gold Standard는 조직검사이지만 시간적·비용적인 측면에서 제한점이 있다. 현재 만성간질환 진단을 위해 최우선 시행하고 있는 검사는 혈액검사이며 진단정확도가 낮은 것으로 보고된다. 영상진단검사는 검사비용 측면에서 혈액검사보다 비싸며 진단정확도 측면에서 조직검사를 대체하기에는 정확도 향상이 요구된다. 본 연구에서는 획득된 의료영상을 활용하여 간세포 이질성과 결정성을 신속하게 정량 분석할 수 있는 소프트웨어를 개발하고 만성간질환 환자를 대상으로 정량 평가함으로서 임상활용 가능성을 확인하고자 한다.

• The Journal of the Korea Contents Association
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• v.12 no.6
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• pp.265-279
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• 2012

In this study, I tried to find out the ecosystem factors which influence suicide thoughts of elderly that care for a chronic invalid. Ecosystem factors are consist of personal system, familial system and social system, tried to analysis ecosystem factors with characteristics of social population that influence suicide thoughts. For the study, I collected 274 samples from people of 55 year-old care a chronic invalid adults who reside of in Gyeonggi-do. I used factor analysis, reliability analysis, multi-regression, t-test, ANOVA with SPSS 18.0. The results are as follows. First, suicide thoughts had affected by personal characteristics and the duty of supporting selected independent variable. Second, familial system as familial characteristics and familial support had a strong influence on suicide thoughts by long-term care and deficient familial support. Third, the result of study, social support and participation of social activities apply as independent variable then every factors of social support are negative influence but participation of social activities are not influence.

• Clinical and Experimental Reproductive Medicine
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• v.33 no.3
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• pp.199-205
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• 2006

Objective: The aim of this study was to evaluate the correlation between severity of endometriosis and the incidence of endometrial polyp. Methods: The study population consisted of six hundred thirty-one women who had undergone laparoscopic operation due to infertility, severe dysmenorrhea or ovarian tumors. We divided two groups: 434 women with endometriosis (study group) and 197 women without the disease (control group). The presence of endometriosis was documented by diagnostic or therapeutic laparoscopic operation and the disease severity was scored according to revised The American Fertility Society classification. We confirmed the endometrial polyps by pathologic examination after hysteroscopic polypectomy, and compared endometrial polyp incidence according to severity of endometriosis. Results: There was no significant difference between groups with regard to age, mean duration of infertility. Endometrial polyps were found in 274 women (63.0%) with endometriosis and in 58 controls (29.8%, p=0.0000). The incidence of endometrial polyps differed significantly according to stage of endometriosis. The incidence of endometrial polyps were 77/142 (54.2%), 58/90 (64.4%), 73/108 (67.6%, p<0.05), 66/94 (70.2%, p<0.05) in endometriosis stage I, II, III, and IV. There was a linear correlation between stage of endometriosis and endometrial polyps incidence (p=0.008). Conclusion: Endometriosis is accompanied by endometrial polyps. This results showed positive correlation between severity of the endometriosis and incidence of endometrial polyps. It is the possible mechanism for low pregnancy rate in the severe endometriosis.

• Clinical and Experimental Pediatrics
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• v.49 no.2
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• pp.192-197
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• 2006

Purpose : Vascular endothelial growth factor(VEGF) is a key cytokine for controlling vascular permeability and angiogenesis, which is one of the major findings in airway remodeling. However, it is not well known if it is associated with acute lower respiratory tract disease such as lobar pneumonia. The aim of this study is to compare serum VEGF levels in patients with asthma according to its severity and duration of cough, and to compare its levels with children with lobar pneumonia. Methods : Using a sandwich enzyme-linked immunosorbent assay, the serum VEGF levels were measured in 16 mild asthmatics, 14 moderate to severe asthmatics, six children with lobar pneumonia, and 22 control subjects. The asthmatics were also classified into three groups according to the duration of cough. Serum VEGF levels were compared in each group. Results : Serum VEGF levels were significantly increased in the children with moderate to severe asthma and lobar pneumonia compared to the children with mild asthma and control subjects. Serum VEGF levels were higher in children with chronic coughs of more than two weeks than in children with coughs lasting less than two weeks. Serum levels of VEGF showed positive correlations with blood platelet and white blood cell counts. Conclusion : VEGF increased according to the severity of asthma and duration of cough in children with asthma. It may play an important role not only in chronic airway inflammation, but also in the acute inflammation in children with lower respiratory tract disease.