• Journal of the Institute of Electronics and Information Engineers
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• v.52 no.1
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• pp.135-139
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• 2015

The address discharge time lags are investigated in each subfield time in AC plasma display panel and a modified driving waveform is proposed to reduce the address discharge time lag by applying different additional scan voltage under no misfiring discharge production. The weak plasma discharge in AC PDP is generated by applying high positive-going ramp waveform to the scan electrode during the first reset period and that induce the production of the priming particle and wall charge. Because the wall charge becomes the wall voltage in a cell, the wall plus external address voltage produce the address discharge. However, as the wall charge in a cell is gradually disappeared as time passed, the address discharge time in the subfield time for 1 TV frame is lagged. In the first subfield time, the address discharge is faster produced than the other subfield time because the wall charge are much remained by the high positive-going ramp voltage during the reset period in the first subfield time. Meanwhile, from the second to last subfield, the address discharge production time is gradually delayed due to the dissipation of the wall charge in a cell. In this study, the address discharge time lags are measured in each subfield time and the total address discharge time lags are shortened by applying the different additional scan voltage during the address period in each the subfield time.

• The Korean Journal of Nuclear Medicine
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• v.32 no.4
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• pp.374-381
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• 1998

Purpose: I-131 labeled (2'-deoxy-2'-iodo-${\beta}$-D-arabinofuranosyl) adenine (IAD) may be involved in DNA synthesis during active proliferation of tumor cells. We conducted this study to find out the biodistribution of IAD and it's feasibility for scintigraphic tumor imaging. Materials and Methods: Tosyl acetyl-adenosine was dissolved in acetonitrile, and I-131-NaI was added and heated to synthesize IAD. Female Fisher 344 rats innoculated with breast tumor cells were injected with 0.27 MBq of IAD. Rats were sacrificed at 0.5, 1, 2, 4, 24h and the % of injected dose per gram of tissue (%ID/g) was determined. For scintigraphy, rats bearing breast cancer were administered with 1.11 MBq of IAD and imaging was performed after 2 and 24h. Then, rat body was fixed and microtomized slice was placed on radiographic film for autoradiography. Results: %ID/g of tumor was 0.74 (0.5h),0.73 (1h), 0.55 (2h), 0.38 (4h), and 0.05 (24h), respectively. At 1h after injection, %ID/g of tumor was higher than that of heart (0.34), liver (0.42), spleen (0.47), kidney (0.69), muscle (0.14), bone (0.33) and intestine (0.51). However, %ID/g of tumor was lower than blood (1.06), lung (0.77), and thyroid (177.71). At 4h, %ID/g of tumor in comparison with other tissue did not change. Tumor contrast expressed by tumor to blood ratio was 0.69 and tumor to muscle ratio was 5.11 at 1h. However, these ratios did not improve through 24h. On autoradiogram and scintigraphy at 2 and 24 hour, the tumor was well visualized. Conclusion: This results suggest that IAD may have a potential for tumor scintigraphy. However, further work is needed to improve localization in tumor tissue.

• Clinical and Experimental Pediatrics
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• v.51 no.10
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• pp.1058-1064
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• 2008

Purpose : This study aimed to assess current knowledge of and training experiences with the intraosseous (IO) line among emergency medicine (EM) and pediatric residents who care for critically ill children and to evaluate the educational effectiveness of the IO line workshop. Methods : During May and June 2008, a workshops on IO line insertion was held for EM and pediatric residents. The workshop comprised a 45-min lecture and a 15-min hands-on session. A semi-drill type EZ-IO machine was used for education. Self-assessment questionnaires gauged residents knowledge of and experiences with IO line insertion or bone marrow (BM) examination and their confidence with IO line insertion before and after the workshop. Performance tests were completed for skill evaluation. Results : Forty-five pediatric residents and 22 EM residents participated in the workshop. The pre-educational questionnaire revealed that EM residents had more educational experience in IO line insertion than pediatric residents (P<0.001), while pediatric residents reported more experience in BM examination (P<0.001). The post-educational questionnaire showed a statistically significant higher percentage of correct answers (P<0.001). Although the pediatric residents inserted an IO line more quickly (P=0.001), most residents (88.7%) succeeded in IO line insertion on their first attempt; there was no difference in the groups success rates. Both groups showed higher confidence in performing IO line insertion after training (P<0.001). Conclusion : Observed educational effectiveness in both knowledge and confidence of IO line insertion skill suggest educational opportunities for pediatric and EM residents should be increased.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.31 no.4
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• pp.508-515
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• 1998

An antihypercholesterolemic effect was observed by intraperitoneal injection of the seaweed Porphya yezoensis extract. Hypercholesterolemia was induced by intraperitoneal injection of Triton WR-1339 (600 $\mu$g/g-body weight) into a mouse. Maximum level of blood cholesterol was reached at 20 hours after Triton injection. By simultaneous injection of the p. yezoensis extract (30 $\mu$g/g-body weight) with the Triton into each right and left sides of the peritoneal cavity, levels of total cholesterol and low density lipoprotein were decreased to $37\%$ and $24\%$ compared to Triton injection only. For histochemical changes, hepatic tissues obtained at 40 hours after injection of the Triton and the p. yezoensis extract were fixed in fromol-calcium solution. Numbers of lipid drops and cholesterol particles decreased in the portal space of the hepatic cytoplasm. This indicates that the accumulation of lipid, including cholesterol, caused by Triton was prevented by the antihypercholesterolemic effect of extract from the seaweed p. yezoensis.

• The Korean Journal of Nuclear Medicine Technology
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• v.14 no.1
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• pp.94-100
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• 2010

Purpose: We can evaluate function of kidney by Glomerular Filtration Rate (GFR) test using $^{99m}Tc$-DTPA which is simple. This test is influenced by several parameter such as net syringe count, kidney depth, corrected kidney count, acquisition time and characters of gamma camera. In this study, we evaluated predose count according to matrix size in the GFR test using $^{99m}Tc$-DTPA. Materials and Methods: Gamma camera of Infinia in GE was used, and LEGP collimator, three types of matrix size ($64{\times}64$, $128{\times}128$, $256{\times}256$) and 1.0 of zoom factor were applied. We increased radioactivity concentration from 222 (6), 296 (8), 370 (10), 444 (12) up to 518 MBq (14 mCi) respectively and acquired images according to matrix size at 30 cm distance from detector. Lastly, we evaluated these values and then substituted them for GFR formula. Results: In $64{\times}64$, $128{\times}128$ and $256{\times}256$ of matrix size, counts per second was 26.8, 34.5, 41.5, 49.1 and 55.3 kcps, 25.3, 33.4, 41.0, 48.4 and 54.3 kcps and 25.5, 33.7, 40.8, 48.1 and 54.7 kcps respectively. Total counts for 5 second were 134, 172, 208, 245 and 276 kcounts from $64{\times}64$, 127, 172, 205, 242, 271 kcounts from $128{\times}128$, and 137, 168, 204, 240 and 273 kcounts from $256{\times}256$, and total counts for 60 seconds were 1,503, 1,866, 2,093, 2,280, 2,321 kcounts, 1,511, 1,994, 2,453, 2,890 and 3,244 kcounts, and 1,524, 2,011, 2,439, 2,869 and 3,268 kcounts respectively. It is different from 0 to 30.02 % of percentage difference in $64{\times}64$ of matrix size. But in $128{\times}128$ and $256{\times}256$, it is showed 0.60 and 0.69 % of maximum value each. GFR of percentage difference in $64{\times}64$ represented 6.77% of 222 MBq (6 mCi), 42.89 % of 518 MBq (14 mCi) at 60 seconds respectively. However it is represented 0.60 and 0.63 % each in $128{\times}128$ and $256{\times}256$. Conclusion: There was no big difference in total counts of percentage difference and GFR values acquiring from $128{\times}128$ and $256{\times}256$ of matrix size. But in $64{\times}64$ of matrix size when the total count exceeded 1,500 kcounts, the overflow phenomenon was appeared differently according to predose radioactivity of concentration and acquisition time. Therefore, we must optimize matrix size and net syringe count considering the total count of predose to get accurate GFR results.

• Clinical and Experimental Reproductive Medicine
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• v.30 no.2
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• pp.151-163
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• 2003

연구목적: Estrogen은 포유류의 생리주기와 착상과정에서 중요한 조절인자로 작용한다. 본 연구에서는 난소 절제된 생쥐의 자궁에서 estrogen에 의해 직접 또는 간접적으로 조절되어 발현하는 유전자를 분석하고자 하였다. 연구재료 및 방법: 생후 8주된 생쥐의 양쪽 난소를 절제하고 14일 동안 회복기간이 지난 후, estrogen (300 ng/mouse)을 피하로 주사하였다. Estrogen 주사 후 6, 12시간째 자궁을 적출하여 cDNA microarray와 laser capture microdissection (LCM) 기술을 이용하여 estrogen에 의해 조절되는 유전자의 시공간적인 발현 양상을 조사하였다. 결 과: Estrogen 주사 후 6시간째에는 조사된 전체 유전자 가운데 0.9% (증가 22, 감소 49), 12시간째에는 8.4% (증가 351, 감소 287)에 해당되는 유전자가 두 배 이상 증가 혹은 감소하는 결과를 보였다. 또한 일부 증감된 유전자를 선택한 후 LCM 기술을 이용하여 시공간적인 발현양상을 확인한 결과 자궁내막상피세포에서만 estrogen에 의해 유전자의 발현이 증가되는 일부 유전자를 선별하였다. 결 론: 이상의 결과들을 종합해보면 1) estrogen에 의해 조절되는 유전자의 수나 증감의 정도는 12시간 이후에 더 많고, 크게 조절되며, 2) 유전자의 조절부위가 자궁의 특이적인 세포층에서 시공간적으로 조절됨을 의미한다. 이러한 유전자의 정보는 생리주기 또는 착상과정의 분자생물학적 기작을 이해하는 데 도움이 될 것이다.

• Journal of Nutrition and Health
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• v.22 no.4
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• pp.237-246
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• 1989

The objective of this study was to determine the metabolic effect of exogenous insulin on Sprague-Dawley rats. In a short-term study, the rats were injected insulin and sacrificed at 0.50, 1, 1.5, 2, 4 and 6hr, respectively. Another group of the rats were injected long-acting insulin everyday and sacrificed at 0, 10, 20 and 30days, respectively. Levels of hemoglobin, hematocrit, plasma glucose, plasma protein, plasma albmin, plasma lipids, cholesterol were determined for each experimental group. Also microscopic observation of fat infiltration of liver and aorta performed. No significant abnormality was abserved either at the short-term or at the long-term insulin injection on normal rats.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2004.05a
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• pp.243-243
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• 2004

상용화된 주사식 전자현미경(SEM)을 기본 구조로 하는 가공 시스템을 구축하여 전자빔(Electron beam)을 이용한 초미세 패턴(Nano pattern) 등 형상의 직접 성형, 혹은 직접 묘화(Direct writing) 가공을 수행하기 위해서는 크게 분류하여 연속적으로 스캐닝되는 전자빔을 요구에 따라 적절하게 극히 짧은 시간 내에 개폐하는 빔 블랭커(Beam blanker)와 효율적으로 초미세 패턴 등의 형상을 설계ㆍ가공하기 위한 전용 S/W의 두 가지 요소가 반드시 적용되어야 한다.(중략)

• Proceedings of the Korean Society of Developmental Biology Conference
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• 2001.02a
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• pp.71-73
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• 2001

밀어 (Rhinogobius brunneus)의 난자형성과정에서 난황전구 단백질 (vitellogenin, Vg)의 변화 및 estrogen에 의한 혈청단백질의 유도에 관하여 조사하였다. 혈청내 Vg는 분자량 190, 130 및 115 kDa(reduced form)으로 난자의 성숙과정에서 peptide cleavage가 일어났다. 수컷 밀어에 17$\beta$-estradiol을 1회 주사한 후 48시간에 다량의 Vg로 추정되는 단백질이 유도되어 1주간 지속되었으며 이후로 감소하였다. 이러한 현상은 동계적응 밀어에서는 관찰되지 않았다. 환경 estiogen의 일종인 nonylphenol을 주사하여 Vg으로 추측되는 혈청단백을 유도하였다. 밀어는 환경에스트로젠에 의한 수컷에서 Vg유도에 적합한 실험어류로 사료된다.

• Journal of Broadcast Engineering
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• v.9 no.1
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• pp.43-53
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• 2004

In this paper, we propose a robust deinterlacing algorithm which combines edge dependent interpolation (EDI) and global motion compensation (GMC). Generally, EDI algorithm shows a visually better performance than any other deinterlacing algorithm using one field. However, due to the restriction of information in one field, a high duality progressive image from Interlaced sources cannot be acquired by intrafield methods. On the contrary, since algorithms based on motion compensation make use of not only spatial information but also temporal information, they yield better results than those of using one field. However, performance of algorithms based on motion compensation depends on the performance of motion estimation. Hence, the proposed algorithm makes use of mixing process of EDI and GMC. In order to obtain the best result, an adaptive thresholding algorithm for detecting the failure of GMC is proposed. Experimental results indicate that the proposed algorithm outperforms the conventional approaches with respect to both objective and subjective criteria.