• Tuberculosis and Respiratory Diseases
• /
• v.43 no.5
• /
• pp.779-785
• /
• 1996

Wegener's granulomatosis is characterized by necrotizing granulomatous vasculitis affecting upper and lower respiratory tracts and kidneys. Vascular lesions commonly involve capillaries and small vessels but, less commonly larger vessels. We report a 46-year-old male patient of Wegener's granulomatosis associated with paranasal sinusitis, pulmonary consolidations, glomerulonephritis, skin lesions with obstruction of both anterior tibial and peroneal arteries. Several necrotic lesions of the toes had progressed to gangrene and both transmetatarsal amputations were done. The patient continued to receive cyclophosphamide and prednisolone.

• Journal of the Korea institute for structural maintenance and inspection
• /
• v.19 no.4
• /
• pp.109-115
• /
• 2015

High performance fiber reinforced cementitious composite (HPFRCC) can provide high fracture energy absorption as well as high strength with high fiber volume fraction. The increased fracture energy helps resisting high frequency loadings, such as earthquake, impact or blast. This study investigates the flexural performance of slurry infiltrated fiber concrete (SIFCON), one of the important HPFRCC, with respect to varying fiber volume fraction. The maximum fiber volume fraction was 8.0 % and reduced to 6.0% by 0.5% and the maximum volume fraction is obtained by packing fibers with simple tapping by hands. The used fiber was a steel fiber with the length 30 mm and the diameter of 0.5 mm. The flexural strengths were 48.7 MPa at 8.0 % and 22.8 MPa at 6.0 %. The measured flexural strength is much higher compared to other cememtitious composite materials but decreased proportional to the fractions. This result implies that for SIFCON considered herein the reduced amount of steel fibers may affect its flexural performance in a negatively way. The flexural toughness, an index to represent the fracture energy absorption, also decreased with the reduced fiber amount.

• Journal of the Korean Recycled Construction Resources Institute
• /
• v.2 no.3
• /
• pp.196-201
• /
• 2014

As political circumstances in oversea countries and Korea varies, the risk of vulnerability from unexpected extreme loading conditions, such as explosions or extreme impacts, also increased. In addition, construction companies in Korea recently have taken chances of overseas expansion to countries where their domestic situations are not in rest. Therefore, the resistance of construction materials for blast or impact loading become taking more consideration from engineering field. This study is a part of the research to develop a high performance fiber reinforced cementitious composite materials with high volume steel fibers and primary purpose of this study is to find an optimum mix proportions of in-fill slurry. In order to accomplish the tasks this study performed experimental investigations on the slurry for consistency, compressive strength, flowability, J-penetration, bleeding and rheology properties as well as mechanical properties, compressive and flexural strength, with respect to different mix proportions.

• Journal of the Institute of Electronics Engineers of Korea SP
• /
• v.48 no.4
• /
• pp.98-106
• /
• 2011

Since prediction processes such as motion estimation motion compensation are not at the WZ video encoder but at its decoder, WZ video compression cannot have better performance than that of conventional video encoder. In order to implement the prediction process with low complexity at the encoder, WZ residual coding was proposed. Instead of original WZ frames, WZ residual coding encodes the residual signal between key frames and WZ frames. Although the proposed WZ residual coding has good performance in pixel domain, it does not have any improvements in transform domain compared to transform domain WZ coding. The WZ residual coding in transform domain is difficult to have better performance, because pre-defined quantization matrices in WZ coding are not compatible with WZ residual coding. In this paper, we propose a new quantization method modifying quantization matrix and quantization step size adaptively for transform domain WZ residual coding. Experimental result shows 22% gain in BDBR and 1.2dB gain in BDPSNR.

• Journal of Broadcast Engineering
• /
• v.17 no.1
• /
• pp.140-151
• /
• 2012

In Wyner-Ziv coding, key picture is encoded by conventional H.264/AVC intra coding which has low complexity. Although inter coding is more efficient than intra coding, its complexity is much higher than intra coding due to its motion estimation. Since the main feature of Wyner-Ziv coding is low complexity of encoder, inter coding is not suitable to encode key picture in Wyner-Ziv coding. However, inter picture coding with zero motion vector can be usable for Wyner-Ziv key picture coding instead of intra coding. Moreover, while current transform-domain Wyner-Ziv residual coding only utilizes temporal correlation of WZ picture, if zero motion coding is jointly used to encode key picture in transform-domain Wyner-Ziv residual coding, there will be a significant improvement in R-D performance. Experimental results show that the complexity of Wyner-Ziv coding with the proposed zero motion key picture coding is higher than conventional Wyner-Ziv coding with intra key picture coding by about 9%, however, there are BDBR gains up to 54%. Additionally, if the proposed zero motion key coding is implemented on top of the transform-domain Wyner-Ziv residual coding, the result shows rate gains up to 70% in BDBR compared to conventional Wyner-Ziv coding with intra key picture coding.

• Tuberculosis and Respiratory Diseases
• /
• v.44 no.4
• /
• pp.766-775
• /
• 1997

Background : Primary malignant tumors of the trachea are extremely rare entities and account for a mere 0.1 per cent of all malignancies of the respiratory tract. Because of vague localizing signs, symptoms and a usually negative routine chest film, the patients with tracheal tumors are often treated for asthma or chronic obstructive pulmonary disease for considerable period of time before correct diagnosis. Method : We have made a review of the 17 cases of primary tracheal tumors in recent 15 years. We reviewed the clinical features including history of smoking and respiratory symptoms, the official readings of initial routine chest film, the cytologic examination of sputum, the time of delay in diagnosis, and the response according to the therapeutic modalities. Results : Eight out of 9 patients with squamous cell carcinoma(SCC) were above 50 years old, five out of 6 patients with adenoid cystic carcinoma(ACC) were below 50 years old. The most common location of primary tracheal tumors was the upper one-third of trachea in 8 cases(47%). The most frequent symptoms were dyspnea in 13/17 cases(76%) and then stridor or wheezing, cough. and sputum in order. The routine chest roentgenographic examinations were not helpful to diagnose tracheal carcinoma and the cytologic examinations of sputums were helpful to diagnose tracheal carcinoma in only one case with adenocarcinoma. The mean times of delay in diagnosis of patients with sec and ACC were 5 months and 24.9 months respectively. We had bronchial asthma in 8 cases(47%) and tracheal tumors in 4 cases(23%) as initial clinical impression. Conclusion : We would like to perform more comprehensive diagnostic tools(high KVP technique, the fibroptic bronchoscopic examination, chest CT scan etc.) in patients who had the suggestive points for the tracheal tumorse(1. unexplained hemoptysis or hoarsness, 2. inspiratory wheezing or stridor, 3. wax and waning of dyspnea according to changes of position, 4. progressive asthmatics unresponsive to antiasthmatic therapy) and radical resection of tumor or external radiation therapy with curative aim as possible.

• Tuberculosis and Respiratory Diseases
• /
• v.53 no.3
• /
• pp.265-274
• /
• 2002

Background : Tumor associated antigens, which are produced specifically by tumor cells, are promising targets for the early diagnosis and immunotherapy. Among the tumor associated antigens, MAGE (a melanoma antigen), BAGE, GAGE, PRAME and NY-ESO were named as cancer/testis specific antigens they are detected exclusively in the testis or cancer cells If MAGE is easily detectable in the sputum, it would become a convenient method for diagnosing lung cancer. This study was undertaken to investigate MAGE expression in the induced sputum obtained from lung cancer patients. Materials and Methods : In 14 control patients and 30 lung cancer patients, the induced sputum was collected after inhaling 3% saline(5 cc) delivered by nebulizer for approximately 5 minutes after a mouth rinse and bronchodilator inhalation. The induced sputum was placed in a conservative-mixed solution (guanidinium isothiocyanate, Triton X-100). The total cellular mRNA was extracted from the cells and RT PCR and nested PCR were run in 30 and 35 cycles respectively, with two different types of primers specially designed to detect six subtypes of MAGE DNA simultaneously. Results : MAGE expression was not detected in the 14 controls, but in the 30 cancer patients, MAGE was found in 24 patients (80%, p=0.001). In the cancer patients, there were no differences in the expression level according to the tissue types (squamous cell cancer 13/17, adenocarcinoma 7/9, and small cell cancer 4/4, p-0.56). Among the 24 MAGE-positive patients, the tumor was not visible on a bronchoscopy in 11 patients (45.8%). Conclusion : A study of MAGE in induced sputum appears to be a useful and complementary method in the diagnosis of lung cancer. A further prospective study with more patients is recommended.

• Tuberculosis and Respiratory Diseases
• /
• v.59 no.5
• /
• pp.504-509
• /
• 2005

Background : Endobronchial tumors cause life-threatening dyspnea and can lower the quality of life due to central airway obstruction. In those cases with an intraluminal tumor, various bronchoscopic techniques are available for tumor debulking. The therapeutic effect of bronchoscopic electrocautery for palliation in patients with a symptomatic tumor obstruction was studied. Method : Nineteen patients with bronchogenic carcinomas (n=15) and metastatic tumors affecting the bronchi (n=4), between March 2002 and March 2005, were enrolled in this study. Electrocautery was performed under local anesthesia using an electroprobe and diathermic snare. Using flexible bronchoscopy, a follow-up bronchoscopic examination was performed 3-4 days later. Symptom improvement was evaluated by $FEV_1$, FVC and dyspnea score (Modified Borg Category Scale (0~10)), both before and after the electrocautery. Results : The success rate of electrocautery on the follow up examination was 84%. Patients with endoluminal airway lesions had a mean overall decrease in the size of the obstruction to $47.8{\pm}15.7%$. The mean Improvement in the dyspnea score immediately after the endobronchial tumor debulking was $2.78{\pm}1.42$. The average improvements in the $FEV_1$ and FVC after electrocautery were $0.32{\pm}0.19L$ and $0.5{\pm}0.22L$, respectively. There were 2 cases of complications related with electrocautery (one each of pneumothorax and pneumonia). Conclusion : Electrocautery using an electroprobe and diathermic snare was an effective and safe palliative treatment for a symptomatic endoluminal airway obstruction in lung cancer.

• Tuberculosis and Respiratory Diseases
• /
• v.45 no.5
• /
• pp.1031-1038
• /
• 1998

Background: Most of malignant pleural effusions are serous but 8-33% of them are bloody. We wanted to evaluate the relationships between gross appearance and pleural CEA level or results of histocytology in malignancy associated pleural effusions. We also tried to reevaluate the meaning of CEA measurement in histocytologically proved or unproved malignancy associated pleural effusions. Methods: We studied 98 cases of malignancy associated pleural effusions, 50 cases of histocytologically proven malignant effusions and 48 cases of histocytologically unproven paramalignant effusions. We had observed gross appearance and conventional laboratory values and CEA levels for pleural effusions. Results: 44.9% of malignancy associated effusions were bloody(63.6% of bloody effusions were histocytologically proven malignant effusion). 65.0% of malignancy associated pleural effusions which have RBCs numbers over $100,000/mm^3$ were cytologically proven malignant effusions. 72.7% of cytologically proven malignant effusions had increased pleural fluid CEA level over 10 ng/ml. 58.2% of cases with pleural CEA over 10 ng/ml had positive results in pleural bistocytology. There was no definable relationships between pleural fluid CEA elevation and RBCs numbers and results of pleural fluid cytology. Conclusion: About half of the cases with malignancy associated pleural effusions were bloody. Histocytologically proven malignant effusions were more common in bloody effusion than non-bloody effusion(63.6% Vs 38.9%). But increased red blood cell numbers was not associated with positivity of pleural histocytology. Pleural fluid CEA elevation(over 10 ng/ml) was not correlated with positive pleural histocytology. But pleural fluid CEA elevation was rare in nonmalignant pleural effusions, and than pleural CEA measurement in uncertain pleural effusions maybe helpful to distinguishes its origin.

• Tuberculosis and Respiratory Diseases
• /
• v.51 no.3
• /
• pp.248-259
• /
• 2001

Background : In diagnosis or monitor of the airway obstruction in bronchial asthma, the measurement of $FEV_1$ in the standard method because of its reproducibility and accuracy. But the measurement of peak expiratory flow(PEF) by peak flow meter is much simpler and easier than that of $FEV_1$ especially in children. Yet there have been still no data of the predicted normal values of PEF measured by peak flow meter in Korean children. This study was conducted to provide equations to predict the normal value of PEF and correlation between PEF and $FEV_1$ in healthy children. Method : PEF was measured by MiniWright peak flow meter, and the forced expiratory volume and the maximum expiratory flow volume curves were measured by Microspiro HI 501(Chest Co.) in 346 healthy children(age:5-16 years, 194 boys and 152 girls) without any respiratory symptoms during 2 weeks before the study. The regression equations for various ventilatory parameters according to age and/or height, and the regression equations of $FEV_1$ by PEF were derived. Results : 1. The regression equation for PEF(L/min) was: $12.6{\times}$age(year)+$3.4{\times}$height(cm)-263($R^2=0.85$) in boys, and $6{\times}$age(year)+$3.9{\times}$height(cm)-293($R^2=0.82$) in girls. 2. The value of FEFmax(L/sec) derived from the maximum expiratory flow volume curves was multiplied by 60 to compare with PEF(L/min), and PEF was faster by 125 L/min in boys and 118 L/min in girls, respectively. 3. The regression equation for $FEV_1$(ml) by PEF(L/min) was:$7{\times}$PEF-550($R^2=0.82$) in boys, and $5.8{\times}$PEF-146 ($R^2=0.81$) in girls, respectively. Conclusion : This study provides regression equations predicting the normal values of PEF by age and/or height in children. And the equations for $FEV_1$, a gold standard of ventilatory function, was predicted by PEF. So, in taking care of children with airway obstruction, PEF measured by the peak flow meter can provide useful information.