• Title/Summary/Keyword: 조직학적 검사

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Comparison of Shear Wave Elastography and Pathologic Results Using BI - RADS Category for Breast Mass (유방종괴에 대한 BI-RADS범주를 이용한 횡탄성 초음파와 병리결과 비교분석)

  • An, Hyun;Im, In-Chul
    • Journal of the Korean Society of Radiology
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    • v.12 no.2
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    • pp.217-223
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    • 2018
  • This study to search the diagnostic performance of shear wave elastography(SWE) in breast mass and to compare the biopsy result and stiffness obtained from shear wave elastography. Diagnostic breast ultrasonography and SWE were targeted for 157 patients who had breast ultrasonography was diagnosed mass from June 2017 to September 2017. Pathology results of 157 patients showed a benign 92 patients(Age, $44.54{\pm}11.84$) and a malignancy 65 patients(Age, $51.55{\pm}10.54$). Final evaluation, biopsy result, and quantitative SWE result were obtained and compared with each other according to Breast Imaging Reporting and Data System(BI-RADS) of diagnostic breast ultrasonography. Quantitative SWE value and pathologic result showed the highest diagnostic specificity of 83.70% in Emean and sensitivity of 89.23% in Emin. Quantitative SWE result and biopsy result is statistically significant.(p=0.000). The optimal cut-off value for malignant lesions was 66.3 kPa and 63.7 kPa, respectively, for the sensitivity, specificity, high maximum mean elasticity value(Emax) and mean elasticity value(Emean) and this showed the highest diagnostic area under the ROC curve(Az) value compared to other SWE measurement(p=0.000). The addition of SWE to conventional US in breast mass make a increase diagnostic specificity and reduce unnecessary biopsy. Therefore, it is expected that it will be helpful to analyze the breast mass using the above analysis and apparatus.

GORHAM-STOUT DISEASE OF THE MANDIBLE: A CASE REPORT (하악골에 발생한 Gorham-Stout 증후군: 증례 보고)

  • Ji, Young-Min;Song, Gin-Ah;Shin, Jung-Hyun;Pang, Kang-Mi;Kim, Soung-Min;Myoung, Hoon;Seo, Byoung-Moo;Choi, Jin-Young;Lee, Jong-Ho;Choung, Pill-Hoon;Kim, Myung-Jin;Hwang, Soon-Jung
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.30 no.6
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    • pp.572-576
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    • 2008
  • Gorham-Stout disease is a rare skeletal disease which is progressive and spontaneous and idiopathic resorption of whole body bone. In the initial stage, the osteolytic site is replaced by histologically benign vascular proliferation without new bone formation and finally by dense fibrous tissues. We encountered with a patient involving the mandible with attention by the clinical, radiographic, scintigraphic, angiographic, and computed tomography. We resected the mandibular lesion which was reconstructed with a fibular free flap. We report literature review with a mandibular lesion involved with Gorham-Stout disease.

Imaging Features of the Intra-abdominal Granulomas in Two Cases (두 케이스에서 복강내 육아종의 영상학적 특징)

  • Choi, Mi-Hyun;Chang, Jin-Hwa;Lee, Hye-Yeon;Kim, Jun-Young;Kim, Wan-Hee;Yoon, Jung-Hee;Choi, Min-Cheol
    • Journal of Veterinary Clinics
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    • v.27 no.3
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    • pp.302-306
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    • 2010
  • One dog and a cat with a history of diarrhea, anorexia and depression were referred. They showed normal laboratory examination results. Radiographic findings included a mid abdominal mass with ill-defined margin and serosal detail loss of peritoneal space. On abdominal ultrasonography, the round mass with heterogenous parenchymal echogenicty with irregular contour was found. It revealed as inflammation through ultrasound guide fine needle aspiration. After surgical removal of the masses in both cases, the clinical signs were resolved and focal pyogranuloma was confirmed through histopathologic examinations.

Imaging Features of Eosinophilic Bronchopneumopathy in Three Dogs (세 마리 개에서 호산구성 기관지폐병증의 영상학적 특징)

  • Ji, Seo-Yeoun;Yi, Kang-Jae;Kim, Jun-Young;Yoon, Jung-Hee;Choi, Min-Cheol
    • Journal of Veterinary Clinics
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    • v.29 no.2
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    • pp.194-197
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    • 2012
  • Three dogs were presented with a history of dyspnea and cough. Physical examination, blood analysis, bronchoalveolar lavage and radiography of three dogs were evaluated. And additionally, computed tomography and lung biopsy were performed on one dog. They showed normal laboratory examination results. The radiographic findings noted alveolar and bronchointerstitial infiltration with bronchiectasis. For one dog, nodules scattered throughout both lung fields on survey radiographs were confused with pulmonary neoplasia, so CT scan was used to rule out neoplasia. Bronchoalveolar lavage revealed abnormally high levels of eosinophils in all dogs. On histopatholgic exam, eosinophilic bronchiolitis and eosinophilic and histiocytic alveolitis were confirmed. Consequently, all dogs were diagnosed as eosinophilic bronchopneumopathy. Symptoms regressed dramtically within a few days after treatment with oral corticosteroids. Radiographs and CT scan are useful for diagnosis and prognosis of eosinophilic bronchopneumopathy.

Effects of Memory and Learning Training on Neurotropic Factor in the Hippocampus after Brain Injury in Rats (뇌손상 흰쥐에서 기억과 학습훈련이 해마의 신경 성장인자에 미치는 영향)

  • Heo, Myoung;Bang, Yoo-Soon
    • The Journal of the Korea Contents Association
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    • v.9 no.2
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    • pp.309-317
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    • 2009
  • This study was to investigate the effects of restoring cognition function and neurotrophic factor in the hippocampus according to memory and learning training in rats affected by brain injury. Brain injury was induced in Sprague-Dawley rats(36 rats) through middle cerebral artery occlusion(MCAo). And then experiment groups were randomly divided into three groups; Group I: Brain injury induction(n=12), Group II: the application for treadmill training after brain injury induction(n=12), Group III: the application for memory and learning training after brain injury induction(n=12). Morris water maze acquisition test and retention test were performed to test cognitive function. And the histological examination was also observed through the immunohistochemistric response of BDNF(brain-derived neurotrophic factor) in the hippocampus. For Morris water maze acquisition test, there were significant interactions among the groups with the time(p<.001). The time to find the circular platform in Group III was more shortened than in Group I, II on the 9th, 10th, 11th and 12th day. For Morris water maze retention test, there were significant differences among the groups(p<.001). The time to dwell on quadrant circular platform in Group III on the 13th day was the longest compared with other groups. And as the result of observing the immunohistochemistric response of BDNF in the hippocampus CA1, the response of immunoreactive positive in Group III on the 7th day increased more than that of Group I, II. These results suggested that the memory and learning training in rats with brain injury has a more significant impact on restoring cognitive function via the changes of neurotropic factor expression and synaptic neuroplasticity.

Pathological Findings of Necrotizing Skeletal Myopathy in Layer Breeder Chickens (산란 종계 골격근의 괴사성 근증에 대한 병리학적 소견)

  • 권용국
    • Korean Journal of Poultry Science
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    • v.30 no.1
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    • pp.55-59
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    • 2003
  • A necrotizing skeletal myopathy was diagnosed in three flocks of 30,000 thirty-eight-week-old layer breeder chickens. The mortality attributed to the myopathy was 17.7%, 12.3% and 21.1% in flock A, B and C, respectively. Clinically, chickens were showed depression, anorexia, posterior paresis, inability to rise, incoordination, reluctance to move, and leg trembling and weakness. The most striking findings at necropsy was pale streaking in the muscles of the thighs and legs. Microscopic lesions included myofiber degeneration and necrosis with massive cellular proliferation interpreted as sarcolemmal nuclei proliferation. Plasma creatine kinase, asparte aminotransferase and akaline phosphatase were markedly elevated. In conclusion, author suggested that submitted chickens were affected by ionophores poisoning.

Significancy of Fine Needle Aspiration Cytology on Thyroid Nodule (갑상선결절에서의 세침흡인세포검사의 진단적 의미)

  • 김기환;심윤상;오경균;이용식;장자준
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1993.05a
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    • pp.104-104
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    • 1993
  • Fine needle aspiration cytology(FNAC) is a valuable method in preoperative diagnosis of thyroid nodule. Authors evaluated one hundred and ten thyroid nodules by FNAC compared with the postoperative histopathologic diagnosis during the period from Jan. 1, 1989 through Dec. 31, 1992. The results were as followed. The sensitivity was 86.5%, specificity 90.4%, false-negative rate 13.5%, false-positive rate 9.6%, positive predictability 91.5%, negative predictability 60.1% and overall diagnostic accuracy 87.3 %.

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Intraluminal Pedunculated Leiomyoma in the Cervical Esophagus - Report of 1 Case - (경부식도에 발생한 강내 육경성 평활근종의 수술 치험)

  • 이형렬;김흥수;박준호;조정수;강대환;이창훈
    • Journal of Chest Surgery
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    • v.35 no.8
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    • pp.621-625
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    • 2002
  • Though leiomyoma is the most common tumor of esophagus, it accounts for only 1% of all esophageal tumors. Most of the leiomyomas are intramural type originating from the muscularis propria and only l% of them is intraluminal pedunculated type originating from muscularis mucosae. Recently, a 30-year-old male was admitted to our hospital because of dysphagia. Radiologic examination showed that intraluminal tumor 5cm in diameter was found at the cervical esophagus. Endoscopic examination showed that the tumor was covered with normal mucosa. The patient underwent surgical excision through the left cervical approach. After full, longitudinal esophagotomy, the intraluminal pedunculated tumor was successfully enucleated. Esophageal leiomyoma was confirmed histopathologically. Postoperative course was uneventful and the patient was relieved from dysphagia.

Histologic Changes of the Immunologically Untreated Xenogenic Valved Conduit (면역학적 처리 없는 이종 심장 판막 도관의 조직학적 변화에 관한 연구)

  • Sung, Ki-Ick;Seo, Jeong-Wook;Kim, Won-Gon
    • Journal of Chest Surgery
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    • v.40 no.1 s.270
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    • pp.1-7
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    • 2007
  • Backgound: It has been shown that the endothelium of cardiac valves and adjacent great vessels have a reduced immune reaction compared to other vessels. We investigated the clinical feasibility of using immunologically untreated xenogenic valves, in a pig-to-goat pulmonary valve conduit implantation model. Material and Method: Porcine pulmonary valve conduits were prepared without specific immunologic treatment and implanted into the right ventricular outflow tract of goats while undergoing cardiopulmonary bypass. Two goats each were assigned to the following observation time intervals: one day, one week, three months, six months and twelve months. Echo-cardiographic examinations were performed prior to sacrifice of the goat to evaluate pulmonary valve function. After the xenograft specimens were retrieved, histological changes were evaluated microscopically. Result: Ten of the twelve animals survived the predetermined observation time intervals. Aneurysmal dilatations, of the anterior wall of the implanted pulmonary artery, were observed at each of three and twelve month-survival animals. A variable degree of pulmonary valve regurgitation was observed on echocardiography. However, valve stenosis, thrombotic occlusion and vegetation were not seen. Microscopically, the nuclei of the donor tissue disappeared as a result of pyknosis and karyolysis; however the three components of the implanted xenografts (the pulmonary artery, the valve and the infundibulum) were gradually replaced by host cells over time, while maintaining their structural integrity. Conclusion: Immunologically untreated xenogenic pulmonary valve conduits were replaced by host cells with few observed clinical problems in a pig to goat pulmonary valve implantation model. Therefore, they might be an alternative bioprosthesis option.