• Title/Summary/Keyword: 조절마비제

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Detoxification and Paralytic Shellfish Poison Profile with Heating, Storage and Treatment of Alkaline in Blue Mussel, Mytilus edulis (알칼리 처리 및 가열, 저장에 따른 진주담치의 마비성 패류독 성분 특성 및 제독)

  • Jang, Jun-Ho;Yun, So-Mi;Lee, Jong-Soo
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.35 no.2
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    • pp.212-218
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    • 2006
  • Changes of paralytic shellfish poison (PSP) contents, toxicity and toxin composition with pH and storing periods at different temperature in toxic blue mussel, Mytilus edulis, were tested by using fluorometric HPLC method. Toxicity at pH 3 was the highest as 14.1 MU/g $(100\%)$ and showed 12.9 MU/g $(92.1\%)$ at pH 5, 9.0 MU/g $(63.8\%)$ at pH 7, 3.6 MU/g $(25.5\%)$ at pH 9 and 0.8 MU/g $(5.7\%)$ at pH 10 which suggested PSP was unstable at alkaline conditions. The decrease in toxicity during storage days was depend on pH and temperature. The toxicity markedly decreased until during the first S day storage $(19.9\~65.3\%)$ at all pH (3, 5, 7, 9) and temperature (30, 5, $-20^{\circ}C$), but, slightly decreased after then till to 30 days. C group toxin (C1 and C2) was the major components and other toxins such as GTX 1,2,3,4, STX and dcSTX were detected. Among the 8 toxins, GTX1,4, dcSTX and STX were firstly decreased according to the decreasing the toxicity at all processing conditions. The toxicity in blue mussel (14.1 MU/g) were able to remove by heating over 10 minutes at pH higher than 7.

Study of Ocular Optical Components (안구의 광학적 구조에 관한 연구)

  • Seo, Y.W.;Choe, Y.J.
    • Journal of Korean Ophthalmic Optics Society
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    • v.5 no.2
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    • pp.139-144
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    • 2000
  • In this study, anterior corneal radius of curvature in korean subjects aged between 16 to 79 year-olds were measured using a keratometer. Refractive power was also measured without cyloplegia. A-mode Ultrasonography was used to measure anterior chamber depth, crystalline lens thickness, vitreous chamber depth & axial length. Measurements of anterior chamber depth of subjects in their 20s were between 3.0 mm & 4.0 mm, 70s age group were between 2 mm & 3.50 mm, showing a decrease with age. Crystalline lens thickness of 20s age group was 2.64 mm while 70s age group was 4.62 mm showing an increase with age. Vitreous chamber depth, unaffected by age, was about 17 mm. Axial length was 24.47 mm in subjects below 40s age groups decreasing to 24.11 mm in above 40s age groups. Corneal radius of curvature was 7.79 mm and 7.72 mm in younger and older age groups respectively, showing a decrease with age.

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Repeatability Assessment of Autorefractor and Accuracy Analysis of Refraction Measurements by Fourier Analysis (자동굴절검사기의 신뢰성 평가 및 Fourier analysis에 의한 정확도 분석)

  • Kim, Tae-Hun;Ye, Ki-Hun;Kim, Jae-Kwang;Sung, A-Young
    • Journal of Korean Ophthalmic Optics Society
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    • v.13 no.2
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    • pp.29-36
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    • 2008
  • Purpose: We have evaluated both the reliability and accuracy of refractive measurement from autorefractor by comparing with subjective refraction data. Methods: Measurements of refractive error were performed on 198 eyes of 99 subjects in noncycloplegic condition. Also we analyzed refraction results and evaluated repeatability and accuracy of subjective refraction and autorefraction. Furthermore we analyzed accuracy of autorefractor by Fourier analysis. Results: Reliability coefficient of the autorefraction for the right eye were determined to by 0.993, 0.974 and 0.925 respectively, in the spherical, cylinderical component and cylinderical Axis. Also, the reliability coefficient of the autorefraction for the left eye were found to be 0.991, 0.948 and 0.886, respectively, in the spherical, cylinderical component and cylinderical Axis. From the Fourier analysis no statistically significant differences in $J_{0}$ component were found between the auto and subjective refraction measurements (p>0.05) whereas difference of refractive power of $J_{45}$ component when compared with the subjective refraction were -0.019, -0.164. Conclusions: We conclude that autorefractormeter can be effectively used to measure the refractive power within the error limits.

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Effect of Ischemic Preconditioning for Preventing Ischemic Injury of the Spinal Cord (척추 신경의 허혈성 손상 예방을 위한 허혈성 전처치의 효과)

  • 홍종면;차성일;송우익;홍장수;임승운;임승운;임승평
    • Journal of Chest Surgery
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    • v.34 no.11
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    • pp.823-830
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    • 2001
  • Background: Paraplegia is a serious complication of thoracic or thoracoabdominal aortic operations, which is related to ischemic injury of the spinal cord induced by low perfusion pressure during cross clamping of the aorta. Ischemic preconditioning of heart or brain with reversible sublethal ischemic injury induces resistance to subsequent lethal ischemia. The aim of this study is to investigate whether ischemic tolerance could be induced by the preconditioning of the spinal cord using swine model. Material and Method: The animals were randomly assigned to three groups: sham group(n=3), control group(n=6) and pre-conditioning group(n=8). In the sham group, we performed the left thoracotomy only without any ischemic injury. In the preconditioning group, the swine received reversible spinal cord ischemic injury by aortic clamping for 20 minutes, whereas control group had no previous aortic cross- clamping. Forty-eight hours later, the aorta was clamped for 30 minutes in both groups. Neurological examination was done 24 hours later, then the animals were euthanized for histopathology and malonedialdehyde(MDA) spectrophotometry assay of the spinal cord. Result: Statistically significant difference in neurological outcome was observed between the control and preconditioning groups at 24 hours after ischemic injury. The incidence of paraplegia and severe paresis was 100% in the control group, and 62.5% in the preconditing group(p=0.028). There was no statistically significant difference in histopathology and MDA assay of the ischemic spinal cord between these two groups with borderline statistical difference in MDA assay(p=0.0745). Conclusion: In the present swine study, ischemic preconditioning could induce tolerance against 30 minute ischemic insult of the spinal cord, although the animals did not completely recover(stand-up or walk). We expect that combining this preconditioning with other currently existing protection methods might lead to a synergistic effect, which warrants further investigation.

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A Longitudinal Study for 3 Years on Myopic Refractive Error Changes of Myopic Children Among Patients of a Korean Optometry Clinic (국내 한 안경원을 방문한 근시 어린이의 3년간 근시도 변화의 추적 연구)

  • Kim, Jin-Suk;Kim, Jae-Do
    • Journal of Korean Ophthalmic Optics Society
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    • v.17 no.3
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    • pp.249-254
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    • 2012
  • Purpose: To investigate amount of myopic progression with increase of age for children myopes among patients of a Korean optometry clinic. Methods: It has followed up 99 children subjects (male 55, female 44) who had no ocular disease and have visited a Korean optometric clinic for mean $33{\pm}8$ months (13 to 54 months) since June of 2001. Mean age of subjects at first visit was $118{\pm}23$months. Non-cycloplegic refractive error were measured 6 times using Canon RK-3(Japan) every mean 6 months. Results: For all subjects mean of refractive errors increased -0.78 D per year from $-2.02{\pm}1.05D$ at first visit to $-4.18{\pm}1.30D$ at final visit with longitudinal study, but -0.19 D per year with cross-section study, which showed a big difference between two methods. Mean of astigmatic refractive error increased -0.15 D per year. As progression of refractive error according to ages at first visit, refractive errors increased -1.04 D per year for 6 years old, -0.9 D for 7 years old, -0.89 D for 8 years old, -0.89 D for 9 years old, -0.74 D for 10 years old, -0.74 D for 11 years old and -0.72 D for 12 years old. And it showed a tendency that the younger age was the higher progression of myopia. However it was not significantly different between each groups. Conclusions: Follow-up results for myopic children among patients of a Korean optometry clinic showed increase of -0.78 D for myopic refractive error and -0.14 D for astigmatic refractive error per year.

Germination Characteristics of Eight Species for Production of Medicinal Crops in Vertical Farms (수직농장에서 약용작물 생산을 위한 8종의 종자 발아 특성)

  • Ga Oun Lee;Hyuk Joon Kwon;Ye Lin Kim;In-Je Kang;Gyu-Sik Yang;Ju-Sung Cho;Ki-Ho Son
    • Journal of Bio-Environment Control
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    • v.33 no.2
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    • pp.79-87
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    • 2024
  • This study confirmed the effects of seed shape, temperature, and light treatment on the germination of eight species of medicinal crops to produce high-value crops in vertical farms. Eight species of medicinal seeds were selected, and the seed shape, seed length, seed width, seed length/width ratio, and one hundred seed weight were measured. The seed moisture content was confirmed. Eight species of medicinal seeds were sown, and the germination rate, germination energy, mean daily germination, and mean germination time were investigated according to temperature (15, 20, 25, 25/15℃) and light treatment. Each of the eight medicinal seeds showed different seed shapes. The moisture content of the seeds showed a moisture content rate of over 20% in the five medicinal seeds. Medicinal seeds that showed a germination rate of over 50% were Angelica gigas Nakai, Codonopsis lanceolata (Siebold & Zucc.) Benth. & Hook.f. ex Trautv., and Achyranthes bidentata Blume var. japonica Miq. seeds. A. gigas seed showed a germination rate of 67.34 ± 4.38% under 25/15℃ light conditions, and C. lanceolata seed showed a germination rate of over 50% under both temperature and light treatment conditions, especially the highest germination rate of 82.67 ± 1.46% under 15℃ dark conditions. Peucedanum japonicum Thunb. seed showed a germination rate of 52.34 ± 1.77% under dark conditions at 20℃, and the highest germination rate was 51.67 ± 3.79% under dark conditions at 15℃. The maximum germination energy was 74.00 ± 4.94% in C. lanceolata seed. The maximum mean daily germination was 14.94 ± 0.15 days in P. japonicum seed. Astragalus penduliflorus Lam. var. dahuricus (DC.) X.Y.Zhu seed showed the highest mean germination time of 34.19 ± 4.71. Through this study, it was determined that A. gigas, C. lanceolata, and A. penduliflours seeds would be suitable for production in vertical farms based on the characteristics of each medicinal seed through analysis of seed germination characteristics.