• Journal of Digital Convergence
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• v.17 no.7
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• pp.179-186
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• 2019

This study was to investigate the factors influencing colorectal cancer(CRC) screening behavior using the health belief model(HBM). It was a descriptive cross-sectional survey. A total of 148 adults aged 50 or older participants were surveyed using structured questionnaires including general characteristics,, health beliefs, and behavioral variables. The data were analyzed by descriptive statistics, t-test, chi-square test and multiple logistic regression using SPSS/WIN 25.0 program. The significant factors influecing CRC screening behavior were perceived sensitivity, spousal experience of CRC screening and family history. Therefore, in order to improve the CRC screening rate, it is necessary to increase the perceived sensitivity through systematic education about the importance of early CRC screening. In addition, it is necessary to assess the spousal screening experience and the family history of subjects and to develop the education program using the partnership of the couple.

• Journal of Genetic Medicine
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• v.7 no.1
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• pp.24-36
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• 2010

Colorectal cancer is one of the most steeply increasing malignancies in Korea. Among 398,824 new patients recorded by the Korea Central Cancer Registry between 2003 and 2005, 47,915 cases involved colorectal cancers, accounting for 12.0 % of all malignancies. In 2002, total number of colorectal cancer cases had accounted for 11.2 % of all malignancies. Hereditary syndromes are the source of approximately 5% to 15% of overall colorectal cancer cases. Hereditary colorectal cancers are divided into two types: hereditary nonpolyposis colorectal cancer (HNPCC), and cancers associated with hereditary colorectal polyposis, including familial adenomatous polyposis (FAP), Peutz-Jeghers syndrome, juvenile polyposis, and the recently reported hMutYH (MYH)-associated polyposis (MAP). Hereditary colorectal cancers have unique clinical features distinct from sporadic cancer because these are due to germline mutations of the causative genes; (i) early age-of-onset of cancer, (ii) frequent association with synchronous or metachronous tumors, (iii) frequent association with extracolonic manifestations. The management strategy for patients with hereditary colorectal cancer is quite different from that for sporadic cancer. Furthermore, screening, genetic counseling, and surveillance for at-risk familial member are also important. A well-organized registry can plays a central role in the surveillance and management of families affected by hereditary colorectal cancers. Here, we discuss each type of hereditary colorectal cancer, focusing on the clinical and genetic characteristics, management, genetic screening, and surveillance.

• 건강소식
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• v.30 no.1 s.326
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• pp.20-21
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• 2006

대장은 소장 끝 부분에서 시작하여 항문까지 이르는 장기로 그 길이는 약 150cm 정도이다. 대장은 소화되고 남은 음식물 찌꺼기를 소장으로부터 받아 그 중에서 수분과 전해질은 흡수하고 나머지는 배설에 적당한 변으로 만들어 이를 저장하고 배출하는 역할을 한다.

• 건강소식
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• v.31 no.1 s.338
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• pp.24-25
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• 2007

• 방재와보험
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• s.103
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• pp.33-35
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• 2004

• 건강소식
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• v.26 no.2 s.279
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• pp.6-13
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• 2002

세계에서 매년 약 1,000만명의 새로운 암환자가 발생하고 있으며, 650만명이 암으로 사망하고 있다. 우리나라에서도 매년 약 85,000명의 새로운 암환자가 등록되고 있으며, 55,000명이 암으로 사망하고 있다. 이는 우리나라 전체 사망자의 20%를 차지하는 수치로서 사망원인으로는 단연 1위에 해당한다. 이처럼 암 발생과 암으로 인한 사망이 급격하게 증가함에 따라 암을 일으키는 원인인자를 밝히고 이러한 원인을 제거하여 암을 예방하려는 노력들이 활발하게 이루어지고 있다. 실제로 몇몇 암의 경우에는 그 발생 원인들이 일부 밝혀지고 있는데, 대표적으로 금연을 통하여 폐암의 발생을 예방하고 간염백신 접종을 통해 간암을 예방하는 경우 등이다. 한편, 세계보건기구에서는 의학적인 관점에서 암 발생인구 가운데 1/3은 예방가능하고, 1/3은 조기진단만 되면 완치가 가능하며, 나머지 1/3의 환자도 적절한 치료를 한다면 완치가 가능한 것으로 보고하고 있다. 특히 우리나라에서 가장 흔한 위암, 유방암, 자궁경부암, 대장암 등은 조기에 발견할 경우 거의 완치가 가능하기 때문에, 이러한 암들에 대해서 정기적으로 검진을 실시할 겨우 암으로 인한 사망을 상당수 줄일 수 있을 것으로 기대된다. 이에 정부는 2002년부터 저소득층을 대상으로 위암, 유방암, 자궁경부암에 대해 조기검진을 무료로 실시하고 있으며, 암 예방 교육 및 홍보를 통하여 국민들에게 암에 대한 정확한 지식과 조기검진의 중요성을 전달하고, 나아가 생활양식의 변화를 유도하여 암을 예방하도록 하는 마스터플랜을 추진하고 있다.

• Proceedings of the Korean Information Science Society Conference
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• 2004.04b
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• pp.583-585
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• 2004

암의 발병을 조기에 예측하고 진단하는 것은 매우 중요하지만 그 과정이 매우 복잡하고 많은 노력이 필요하다. 암이 발생하는 원인은 매우 다양하지만 근본적으로 단백질을 형성하는 유전자에 변화가 오기 때문으로 생각해 볼 수 있다. 유전자 발현 정보로부터 기계적으로 암을 예측하기 위한 과정은 중요한 유전자의 선택, 모델의 학습, 모델을 이용한 예측과정으로 나뉘어 진다. 본 논문에서는 대장암 여부를 유전자 발현 데이터로부터 예측하기 위한 종분화 진화 신경망을 제안한다. 종분화 진화 신경망은 진화 알고리즘을 사용하여 신경망의 구조를 결정하고 종분화 알고리즘을 사용하여 다양한 개체의 생성을 유도한 후 모델의 앙상블을 통해 보다 높은 성능을 내는 방법이다 실험 결과 제안하는 방법이 대장암 예측 cross validation 테스트에서 96.5%의 높은 성능을 보였다.

• Journal of Digestive Cancer Research
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• v.1 no.1
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• pp.1-5
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• 2013

Incidence of colorectal cancer has been increasing in Korea probably due to the westernized life style. Although the technical development of colonoscopy and introduction of screening examination has led to the detection of early colorectal cancer, considerable patients still have clinical symptoms of colorectal obstruction. Most of these patients are old and they have advances stage of cancer or severe co-morbidities. In addition, the emergency operation under poor preparation state of colon can lead to serious mortality or complications. Since the introduction of colorectal stent, there have been a large number of studies for recent 10 years. It seems that the role of colorectal stent in the palliative indication or bridge to surgery has been recognized. A well designed, randomized prospective study with long term data is necessary to support the role of colorectal stent in the malignant colorectal obstruction.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2022.05a
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• pp.396-398
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• 2022

The endoscopic pathological findings of gastrointestinal tract (GIT) are important in the early diagnosis of colorectal cancer. Deep learning based on convolutional nueral network (CNN) has been implemented to solve the subjective analysis problem and to increase the performance of early detection of pathological findings. However, the desired performance is yet to be achieved and CNNs are computationally complex. To solve these problems, in this paper, we propose a vision transformer based endoscopic pathological findings classification for the early detection of colorectal cancer. Publicly available endoscopic images with three pathological findings, including esophagitis, polyps, and ulcerative colitis, each with 1000 images were used. Using our approach, we have achieved a test accuracy of 98% in classifying the three pathological findings.

• Journal of radiological science and technology
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• v.26 no.2
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• pp.43-47
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• 2003

Colorectal cancer produce focal mass or segmental thickening which can be detected with sonography. The purpose of this study was to describe sonographic findings of colorectal cancer. we reviewed sonograms of 51 patients with colorectal cancer in whom sonography was performed before colon study. In 51 patients who had more common coloretal cancer 27cases(53%) had 40 to 50 years of age(60%). Sonographic findings included segmental thickening 42cases, or irregular mass 9 cases. With careful examination, these findings can be detectable, and therefore bowel should be carefully examination in patients with sign and symptoms suggesting carcinoma of the colon and rectum.