• Title/Summary/Keyword: 조기위암

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Synchronous Occurrence of a Gastric Adenocarcinoma and a GIST (Gastrointestinal Stromal Tumor): A Case Report (위에 동시성으로 발생한 조기위암 및 위장관간질종양)

  • Jee, Sung-Bae;Seo, Kyung-Jin;Heo, Hun;Jeon, Hae-Myung
    • Journal of Gastric Cancer
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    • v.7 no.4
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    • pp.261-264
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    • 2007
  • A gastric adenocarcinoma is the second most common cause of cancer deaths worldwide, but there are some geographical differences in its incidence. A gastrointestinal tumor is an uncommon disease with a wide spectrum of aggressive behavior. These two tumors have a distinct pathogenesis, and synchronous occurrence of an adenocarcinoma and a GIST (gastrointestinal stromal tumor) in the stomach is very rare. We report a case of synchronous occurrence of a gastric adenocarcinoma and GIST in a 64-year-old man. We performed the following tests: barium swallowing test, gastroduodenoscopy, and CT scanning. We performed a total gastrectomy, and a 9 em-sized GIST at the fundus and a small early gastric cancer at the antrum were confirmed pathologically. Some explanations for this rare case exist, but in our opinion, the synchronous occurrence is a rare but probable event that can happen in an endemic area. We describe a case of synchronous occurrence of a gastric adenocarcinoma and GIST in the stomach, with a review of the literature.

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Comparative Analysis of Stomach Cancer Stages and Related Factors according to the Diagnosis Path (위암 환자의 진단 경로에 따른 병기 및 관련요인의 차이)

  • Lee, Hyun-Ah;Lee, Tae-Yong;Kim, Young-Ran
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.4
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    • pp.2656-2664
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    • 2015
  • The purpose of this study is to compare the difference between stomach cancer stages and related factors according to the diagnosis path. The self-administered questionnaire was filled out by 375 inpatients with primary stomach cancers who had been scheduled at Chungnam National University Hospital were targeted for the survey during the period from August 1st 2010 to March 31st 2013. Rogistic regression model were estimated to identify related factors between Medical checkups group and symptom group. As a results, the study suggests that early checkups is important because ratio of early stomach cancer is higher in Medical checkups group than in symptom group(p=0.001). And if there was a symptom at diagnosis of stomach cancer, stomach cancer stage appeared to have a strong possibility(p=0.001). If cancer screening has been widely implemented and supported by a large scale prospective studies will be possible even in the most appropriate tests and interval estimation for the country.

Preoperative Chemotherapy in Advanced Stomach Cancer (Cons) (진행성 위암에서의 수술 전 항암화학요법 치료 (in the View of Cons))

  • Oh, Sang Cheul
    • Journal of Gastric Cancer
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    • v.8 no.2
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    • pp.65-69
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    • 2008
  • Surgery is the only curative modality for the treatment of gastric cancer. There has been no drastic improvement in the treatment of gastric cancer with chemotherapy. Clinical trials have attempted to demonstrate the benefit of the preoperative chemotherapy for gastric cancer. The benefit of the use of preoperative chemotherapy or chemoradiotherapy has been demonstrated for other solid cancers such as breast cancer, esophageal cancer and rectal cancer. Despite the rationale of the use of preoperative chemotherapy for patients with gastric cancer, the evidence of positive results with the use of preoperative chemotherapy has not been clear. Recently the British Medical Research Council Adjuvant Gastric Cancer Infusional Chemotherapy (MAGIC) study demonstrated the survival benefit of preoperative and postoperative chemotherapy. However, this study had several problems with the use of a heterogeneous population of patients, the method of surgery and the use of perioperative chemotherapy. Further studies with new drugs are warranted to determine the role of pre-operative chemotherapy for patients with gastric cancer.

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Effectiveness of Positron Emission Tomography in the Pre-operative Staging of Gastric Cancer (위암환자의 술 전 병기 결정에서 PET-CT의 유용성)

  • Park, Shin-Young;Bae, Jung-Min;Kim, Se-Won;Kim, Sang-Woon;Song, Sun-Kyo
    • Journal of Gastric Cancer
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    • v.9 no.3
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    • pp.110-116
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    • 2009
  • Purpose: The aim of this study was to examine the usefulness of positron emission tomography (PET)-computed tomography (CT) in the pre-operative staging of gastric cancer. Materials and Methods: Between February 2006 and August 2008, PET-CT and CT were performed on 70 patients diagnosed with gastric cancer by gastrofiberscopic biopsy. The sensitivities, specificities, Positive predictive value (PPV), and negative predictive value (NPV) of PET-CT and CT imaging for the detection of gastric cancer TNM staging were compared. Results: The detection rates for the primary tumor were as follows: PET-CT, 81.4% (57/70); and CT, 42.9% (30/70). For both early gastric cancer (EGC) and advanced gastric cancer (AGC), PET-CT was more accurate than CT in detecting the lesions. As the size of the tumor exceeded 3 cm, the detection rate increased. The sensitivities, specificities, PPV, and NPV of PET-CT for lymph node staging were 55.6%, 81%, 86.2%, and 45.9%, while the sensitivities, specificities, PPV, and NPV of CT were 40.0%, 85.7%, 85.7% and 40%, respectively. One case of multiple liver metastasis and two cases of dual primary cancer (rectal and pancreatic cancers) were detected by PET-CT. PET-CT also had a higher detection rate for all histologic types of primary tumors. PET-CT was more accurate than CT in detecting primary gastric cancer lesions. The detection of nodal metastasis by PET-CT was similar to CT; small-sized tumors or EGC detection rates were not high. However, PET-CT provided additional information to detect distant metastases and dual primary cancers and reduced unnecessary laparotomies to detect peritoneal seeding or carcinomatosis. Conclusion: It would be useful to make a pre-operative diagnosis of gastric cancer and determine treatment if PET-CT were added to other routine pre-operative studies.

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