• The Korean Journal of Archival Studies
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• no.25
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• pp.197-231
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• 2010

The concept of Government 2.0 is spreading rapidly in many countries and is fundamentally changing existing freedom of information system which has passively responded to information demands. This study aims at discussing possible strategies for a new freedom of information system that is based on the Government 2.0 notion which presents revolutional approaches to public sector information's creation, management, and usage. For the purpose of the study, precedence studies and researches about both freedom of information system and Government 2.0 are analyzed. Furthermore, mutual relationships between them are discussed. Through this discussion, social and economic benefits from freedom of information systems which are based on Government 2.0 are explored. As a case study, Data.gov services in the US, the UK, and Australia which are recognised as a feasible plan to set up Government 2.0 are analyzed. Their three common characteristics- revaluating public sector information's reuse, establishing exclusive agencies, and providing raw data-are discussed. Then, various mashup services which use Data.gov services' raw data are also studied. Issues related to the freedom of information system in South Korea are examined. As a result, a policy framework for establishing Government 2.0 based freedom of Information system is discussed in terms of three aspects, law, technology and organization.

• The Journal of the Convergence on Culture Technology
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• v.10 no.4
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• pp.711-719
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• 2024

This study examined the policy of opening up the Chinese A-share market and its performance in four aspects: institutional investors system, cross-trading system with overseas stock markets, inclusion of A-shares into global indices, and establishment of a new board. Then, the impact of these policies on the Stock Index was empirically analyzed, and it was confirmed that institutional investors system such as QFII and RQFII, cross-trading system with overseas stock markets such as Shanghai-Hong Kong Stock Connect and Shenzhen-Hong Kong Stock Connect, inclusion of A-shares into global indices such as the MSCI EM index and FTSE Russell index, and the establishment of a new board of the Science Innovation Board all had statistically significant positive impacts on the stock index. Based on the results of these analysis, we conclude that China should further expand its stock market opening to the outside world, that mutual efforts are needed to alleviate political conflicts and improve understanding, and that easing industry regulations, including real estate, will help China's economic recovery and foreigners' investment in the A-share market.

• Journal of the Korean Society of Radiology
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• v.18 no.5
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• pp.429-437
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• 2024

The purpose of this study was to analyze changes in thrombus signal within a stent in relation to contrast media dilution ratios during the use of an automatic exposure control (AEC) system. A custom-built flow model phantom was used, with contrast media concentrations increased by 5% increments from 5% to 100%, resulting in a total of 20 variations. The signal intensity(SI) and contrast-to-noise ratio (CNR) of the model vessel, stent, and thrombus were analyzed. The results demonstrated that under no-flow conditions, signal intensity and CNR increased linearly with higher contrast media concentrations. However, under flow conditions, the CNR peaked at concentrations between 60% and 70%. Particularly, in models with thrombi within the stent, the use of undiluted contrast media resulted in the highest CNR, indicating that using undiluted contrast media is effective for detecting thrombi within stents in clinical settings.

• Korean Journal of Clinical Laboratory Science
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• v.56 no.3
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• pp.198-206
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• 2024

EZH2 is a methyltransferase that is a critical target for lymphoma treatment. However, it is not yet widely used in clinical settings. PROteolysis TArgeting Chimeras (PROTACs) represent a novel therapeutic strategy aimed at eliminating proteins that have been a challenging target using conventional small molecules. In our previous research, we compared the small molecules-based EZH2 inhibitor used in clinical settings with a PROTAC-based EZH2 degrader. We found that the PROTAC-based degrader was significantly more effective. Building on this, we further investigated the effects of combining the PROTAC-based EZH2 degrader (dEZH2) with a METTL3 inhibitor, both of which have demonstrated effectiveness in inhibiting cell proliferation and inducing apoptosis in Burkitt's lymphoma. Using the CCK-8 assay, we found that both drugs, alone and in combination, significantly inhibited Daudi and Ramos cell growth in a dose-dependent manner. The combined treatment markedly suppressed cell proliferation and induced apoptosis, as confirmed by Annexin V/PI staining. Our results revealed G2/M phase arrest with a significant decrease in the G0/G1 phase by flow cytometry. Our study also showed increased levels of cleaved PARP, cleaved caspase-3, tumor protein p53 (TP53), and PUMA using the western blot technique, indicating enhanced p53-dependent apoptosis. Our findings suggest that the combination therapy of dEZH2 and iMETTL3 could be a promising approach in the treatment of Burkitt's lymphoma.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.35 no.1
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• pp.173-185
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• 2015

This study aims to investigate the characteristics and types of car accidents and establish a prediction model by analyzing 456 car accidents having occurred in the 11 tunnels in Busan, through statistical analysis techniques. The results of this study can be summarized as below. As a result of analyzing the characteristics of car accidents, it was found that 64.9% of all the car accidents took place in the tunnels between 08:00 and 18:00, which was higher than 45.8 to 46.1% of the car accidents in common roads. As a result of analyzing the types of car accidents, the car-to-car accident type was the majority, and the sole-car accident type in the tunnels was relatively high, compared to that in common roads. Besides, people at the age between 21 and 40 were most involved in car accidents, and in the vehicle type of the first party to car accidents, trucks showed a high proportion, and in the cloud cover, rainy days or cloudy days showed a high proportion unlike clear days. As a result of analyzing the principal components of car accident influence factors, it was found that the first principal components were road, tunnel structure and traffic flow-related factors, the second principal components lighting facility and road structure-related factors, the third principal factors stand-by and lighting facility-related factors, the fourth principal components human and time series-related factors, the fifth principal components human-related factors, the sixth principal components vehicle and traffic flow-related factors, and the seventh principal components meteorological factors. As a result of classifying car accident spots, there were 5 optimized groups classified, and as a result of analyzing each group based on Quantification Theory Type I, it was found that the first group showed low explanation power for the prediction model, while the fourth group showed a middle explanation power and the second, third and fifth groups showed high explanation power for the prediction model. Out of all the items(principal components) over 0.2(a weak correlation) in the partial correlation coefficient absolute value of the prediction model, this study analyzed variables including road environment variables. As a result, main examination items were summarized as proper traffic flow processing, cross-section composition(the width of a road), tunnel structure(the length of a tunnel), the lineal of a road, ventilation facilities and lighting facilities.

• Journal of Elementary Mathematics Education in Korea
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• v.19 no.4
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• pp.501-525
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• 2015

This study analyzes arithmetic word problem of multiplication and division in the mathematics textbooks and workbooks of 3rd grade in elementary school according to 2009 revised curriculum. And we analyzes type of the problem solving ability which 4th graders prefer in the course of arithmetic word problem solving and the problem solving ability as per the type in order to seek efficient teaching methods on arithmetic word problem solving of students. First, in the mathematics textbook and workbook of 3rd grade, arithmetic word problem of multiplication and division suggested various things such as thought opening, activities, finish, and let's check. As per the semantic element, multiplication was classified into 5 types of cumulated addition of same number, rate, comparison, arrayal and combination while division was classified into 2 types of division into equal parts and division by equal part. According to result of analysis, the type of cumulated addition of same number was the most one for multiplication while 2 types of division into equal parts and division by equal part were evenly spread in division. Second, according to 1st test result of arithmetic word problem solving ability in the element of arithmetic operation meaning, 4th grade showed type of cumulated addition of same number as the highest correct answer ratio for multiplication. As for division, 4th grade showed 90% correct answer ratio in 4 questionnaires out of 5 questionnaires. And 2nd test showed arithmetic word problem solving ability in the element of arithmetic operation construction, as for multiplication and division, correct answer ratio was higher in the case that 4th grade students did not know the result than the case they did not know changed amount or initial amount. This was because the case of asking the result was suggested in the mathematics textbook and workbook and therefore, it was difficult for students to understand such questions as changed amount or initial amount which they did not see frequently. Therefore, it is required for students to experience more varied types of problems so that they can more easily recognize problems seen from a textbook and then, improve their understanding of problems and problem solving ability.

• Journal of Digital Convergence
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• v.16 no.9
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• pp.115-123
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• 2018

This study aims to analyze the importance of activating factors in the companies operating in the free trade zone of Pyeongtaek Port by using hierarchical analytical decision making method and suggest implications according to the analysis results. As a result of analyzing the importance of the five factors, it was found that most of the companies in the free trade zone of Pyeongtaek Port were aware of the infrastructure factor (0.330), finance and budget (0.223), organization and operation (0.188), manpower (0.119) in order of importance. In detail, the expansion of the route was recognized as the most important improvement. and Manufacturing companies were judged to be a more important factor in improving the entry conditions of manufacturers and strengthening the distribution of value added. In logistics companies, the importance of manpower is higher than manufacturing companies. The implications for the results of the analysis are diversification of route in Pyeongtaek Port, improvement of the infrastructure near the free trade zone, and The need for institutional improvements. Also, in the future, we suggest the necessity of activation research for non - residents.

• Analytical Science and Technology
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• v.14 no.5
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• pp.410-415
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• 2001

An analytical method has been developed which determines lead in steel samples by inductively coupled plasma mass spectrometry (ICP-MS) with sample introduction by the hydride generation. The lead hydride is not stable and requires and oxidant for the oxidation into metastable Pb(IV) before reduction to $PbH_4$ with $NaBH_4$. A study was carried out to find and optimum lead hydride generation condition for a sample solution with more than $1000{\mu}g/mL$ Fe matrix. $K_2Cr_2O_7$ was found to work as an efficient oxidant when more than $10{\mu}g/mL$ Fe matrix was present. Lactic acid was used with the oxidant as a complexing agent of the metastable Pb(IV) to enhance sensitivity. Optimum concentrations of the sample acidity, oxidant and lactic acid were different depending on the matrix concentration. The isotope dilution method was employed for the quantitation of lead. The determined Pb concentrations of the NIST steel SRM 361 and 362 were in good agreement with the certified values within the uncertainty range.

• Journal of The Korean Association For Science Education
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• v.32 no.4
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• pp.703-716
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• 2012

Frequently, pre-service elementary teachers are asked to write reflective journals on their teaching during teacher education program. However, writing reflective journals can not guarantee pre-service teachers to learn from their experience. In this study, 44 reflective journals of pre-service elementary teachers on their science teaching were analyzed in terms of 'productive reflection', a concept suggested by Davis (2006). Productive reflection may help teachers' effective learning by considering interrelationships among aspects of teaching including learners and learning, subject matter knowledge, assessment, and instruction. The result showed what aspects of teaching were included, emphasized, and integrated in the pre-service elementary teachers' reflective journals. Implications for teacher education would be discussed.

• Informatization Policy
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• v.19 no.4
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• pp.3-26
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• 2012

The purpose of this study is to provide a systematical view point of SNS research published by scholarly journals in communications vis a meta-analysis. A total of 72 articles dealing with SNS issues from 2006 to 2012 were analysed by research theme, related sub-theme, methodology, theoretic rationale, targeted media, and characteristics. Effect research get the largest portion and then user research in terms of a developmental model of media research agenda. A major methodological trend is an online survey and theoretical background is Uses and Gratification. Twitter is the most popular medium researched and SNS is mainly characterized as information provision and seeking as well as relationship forming.