• Journal of Veterinary Clinics
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• v.30 no.2
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• pp.123-126
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• 2013

A 3-month-old male domestic shorthair cat was presented for evaluation of stranguria and hematuria and a 4-year-old male domestic shorthair cat was presented for evaluation of stranguria. For cat 1, a swollen prepuce, erythematous preputial orifice, and urine pooling from the preputial orifice were noted. The preputial orifice was a pinpoint opening and penis was not extruded from the prepuce. For cat 2, a necrotic skin around the preputial orifice, small preputial orifice, and severe urine pooling from the preputial orifice were noted. The round-shaped resection of the tip of the prepuce was performed to increase the diameter of the preputial orifice and remove erythematous fragile skin or a necrotic skin around the preputial orifice and the edematous, redundant preputial mucosa in these 2 cats. The preputial mucosa was then apposed to the ipsilateral incised skin edge. There was no recurrence of clinical signs over 22- and 24-month follow-up period, respectively. The round-shaped resection technique provided adequate enlargement of the preputial orifice to allow extrusion of penis in these 2 cats with a phimosis. This technique could be helpful in cases with skin and mucosa necrosis around the preputial orifice that require round-shaped resection.

• Journal of Dental Rehabilitation and Applied Science
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• v.31 no.2
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• pp.134-142
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• 2015

Lichen planus is an immune-mediated mucocutaneous disease, affects more frequently middle-aged Caucasian women and makes signs and symptoms in the oral mucosa. Cutaneous lichen planus lesions cause itching but they are self-limiting, oral lichen planus lesions are usually chronic, recalcitrant to treatment and potentially premalignant in some cases. Although, oral lichen planus is non-plaque related disease, they possess particular problems because plaque control is complicated by pain and bleeding and might cause plaque-related disease. The resulting condition comprises accumulations of plaque, which again can influence the progress of oral lichen planus with burning sensation, spontaneous gingival bleeding. Thus, it should be noted that both medication and supportive periodontal treatment are essential for the remission of the lesions. This case report introduces topical corticosteroid therapy and supportive periodontal treatment including intensive oral hygiene procedures to obtain an improvement of subjective symptoms and objective changes and to prevent relapse the lesions.

• Journal of Oral Medicine and Pain
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• v.38 no.2
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• pp.109-114
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• 2013

Chemical burn on the oral mucosa is caused by contact with various chemical products and manifests with localized mucositis, keratotic white lesions, bleeding, and painful tissue surface due to the coagulation of the tissue. Policresulen ($Albothyl^{(R)}$) is a topical antiseptic, commonly used over-the-counter drug for vaginitis, thrush and stomatitis. This drug is highly acidic with pH 0.6, and can act as a strong corrosive agent to oral mucosa. When inadvertently used in oral cavity, it may cause chemical burns of oral mucosa, resulting necrosis and bleeding surface resembling to erythema multifome. A 56 years old female patient presented with the chief complaints of painful ulcerations on the tongue, the upper and lower lips. On intraoral examination, an erythromatous, erosive or ulcerative surface covered with inflammatory exudates or bleeding crust is observed on the anterior half of the tongue and the upper and lower lips. She has occasionally applied the policresulen solution topically on the tongue to relieve pain from recurrent focal glossitis for about 10 years. In this time she applied it broadly and repeatedly to the tongue, the upper and lower lips for the purpose of pain relief by herself without instruction by physician or dentist. After cessation of policresulen application, the oral mucosa was rapidly recovered with use of topical steroids. In 2 weeks the lesions subsided completely. In summary, inadvertent use of $Albothyl^{(R)}$ on oral mucosa may result in chemical burn, causing mucosal erosion, ulceration and inflammation. It can be recovered by topical use of corticosteroid for 2 weeks after cessation of using $Albothyl^{(R)}$.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1995.04a
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• pp.89.2-89
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• 1995

일반적으로 기관협착의 치료는 기관절재후 단단문합술로 가능하나 광범위한 기관협착이 발생하였을 때는 그 치료가 매우 어렵다. 이경우는 기도전벽을 개방하여 경부 피부와 기관연을 봉합하는 Trough를 형성한 뒤 이차적으로 연골이식이나 경부 피부를 이용한 피판을 만들어서 기관을 재건하는 Trough방법이 주로 적용되고 있다. 이 때 이식되는 연골은 늑연골 이나 비중격 연골이며 측벽의 재건에는 늑연골이 좋고 전벽의 재건에는 점막이 붙어 있는 비중격 연골의 복합이식편이 사용될 수 있다. 본 교실에서는 기관 절제 후 단단문합술이 불가능하였던 5명의 환자에서 Trough방법을 이용하여 기관 재건에 성공하였기에 그 결과를 보고하고자 한다.

• 월간산업보건
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• s.382
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• pp.11-14
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• 2020

눈, 피부 및 점막 자극의 가능성을 최소화하기 위해 옥시 염화인(phosphorus oxychloride)의 직업적 노출기준 TLV-TWA를 0.1ppm(0.63 mg/㎥)으로 권고하였다. 옥시 염화인 독성의 징후 및 증상으로는 두통, 현기증, 식욕 부진, 메스꺼움, 흉통 및 호흡 곤란이 있고 심한 급성 또는 반복 만성 노출에 의해서는 기관지 폐렴, 폐부종 그리고 신장 손상을 유발한다. 옥시 염화인은 물 또는 습한 공기에서 분해되어 염화수소와 인산을 형성한다. 피부, 감작제(SEN), 발암성 표기와 TLV-STEL을 권고하기에 충분한 자료가 없다.

• Clinical and Experimental Pediatrics
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• v.52 no.2
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• pp.247-250
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• 2009

Stevens-Johnson syndrome (SJS) presents with widespread blisters, erythematous or purpuric macules, and one or more mucous membrane erosions. Various etiologic factors, including infection, vaccination, drug administration, systemic diseases, physical agents, and food have been implicated as causes of SJS. Mycoplasma pneumoniae is the most common infectious agent to cause SJS in children. In recent literature, M. pneumoniae-induced SJS with mucositis that lacks the typical target lesions has been described. We report a case of a 6-year-old boy with swelling, peeling of the lips, and red eyes with photosensitivity. On physical examination, he showed severe oral mucositis and conjunctivitis with no evidence of skin lesions. Mycoplasma antibody, which was positive with titers of more than 1:2,560. For patients presenting with fever and mucositis of unknown origin, M. pneumoniae should be considered.

• Agrochemical news magazine
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• v.24 no.2 s.185
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• pp.9-11
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• 2003

• 대한두경부종양학회:학술대회논문집
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• 1998.11a
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• pp.286.2-287
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• 1998

• The Korean Journal of Pesticide Science
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• v.15 no.3
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• pp.231-237
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• 2011

Highly bio-active plant essential extracts and oils from pepper, clove bud, rosemary and origanum which are selected to develop environment-friendly insecticides was studied for their acute toxicity. The results of acute oral toxicity using rats showed $LD_{50}$ value of over 2,000 mg/kg bw for pepper, clove bud, rosemary and origanum oils. The calculated acute dermal $LD_{50}$ value of pepper was over 4,000 mg/kg bw and anther testing materials was over 4,000 mg/kg bw. The skin irritation test showed that pepper, clove bud and rosemary oils had no irritation while origanum oil had a moderate irritation. According to the eye irritation test, it showed that there was no irritation for pepper and rosemary oils, while there were irritation for clove bud and origanum oils. Consequently, pepper and rosemary oils were shown to be low in toxicity whereas clove bud oil was indicated to cause a mild eye irritability and origanum oil, causing a moderate skin and eye irritability.

• Tuberculosis and Respiratory Diseases
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• v.53 no.2
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• pp.196-201
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• 2002

Malignant melanoma is a highly malignant form of cutaneous cancer derived from melanocytes. The lesion frequently metastasizes to the lymph nodes, lung, liver and bone. However, an endobronchial metastasis and a primary malignant. melanoma of the lung are quite rare. We report a case of an unknown primary malignant melanoma with a pulmonary and endobronchial metastasis in a 34 years old male. He complained of coughing and black-colored sputum. Abnormal skin and mucosal lesions were not found during a physical examination. A chest X-ray revealed multiple nodular masses in both lung fields. A flexible bronchoscopy showed two yellowish small nodules at the entry of left lower bronchus. Vimentin, the S-100 protein, and HMB-45 stain positive melanoma cells were detected at the bronchoscopic biopsy specimen.