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Hypofractionated Radiation Therapy for Early Glottic Cancer - Preliminary Results - (초기 성문암 환자에서의 소분할 조사법을 이용한 방사선치료 - 예비적 결과 -)

  • Wu Hong-Gyun;Hong Semie;Shin Seong Soo;Park Charn Il
    • Radiation Oncology Journal
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    • v.19 no.4
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    • pp.301-305
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    • 2001
  • Purpose : This study was peformed for the evaluation of the feasibility and toxicity of hypofractionated radiation therapy for early glottic cancer Methods and Materials : From February 1999 to February 2000, 20 patients with Histologically confirmed Stage I, II glottic cancer were enrolled into this study. There were 18 males and 2 females, the median age of the patients was 59 years. The distribution of stage distribution was as fellows; T1aN0-16 patients, T1bN0-1 patient, T2N0-3 patients. Eighteen patients underwent laryngomicroscopic biopsy only, and two patients underwent laser cordectomy. All patients received radical radiation therapy (2.5 Gy per fraction, 24 fractions, total 60 Gy). Median duration of treatment was 36 days (range $31\~45\;days$). Results : Radiation therapy were well tolerated. Most common acute reactions were odynophagia and hoarseness, and these reactions resolved after radiation therapy. There were one case of RTOG grade 3 odynophagia $(5\%)$, six cases of grade 3 hoarseness $(30\%)$. Response of radiation therapy was evaluated one month after completion of treatment. All patients revealed complete response. During follow up, total three cases of treatment failure were detected. two cases were local recurrence in 10 and 13 months of radiation therapy and one case was local recurrence and distant metastasis in 2 months of radiation therapy. Conclusion : This hypofractionated radiation therapy schedule was feasible and effective for control of early glottic cancer But longer follow up time would be required to assess the long-term disease control and the late complication by shortening radiation therapy duration.

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Quality Assurance for Intensity Modulated Radiation Therapy (세기조절방사선치료(Intensity Modulated Radiation Therapy; IMRT)의 정도보증(Quality Assurance))

  • Cho Byung Chul;Park Suk Won;Oh Do Hoon;Bae Hoonsik
    • Radiation Oncology Journal
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    • v.19 no.3
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    • pp.275-286
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    • 2001
  • Purpose : To setup procedures of quality assurance (OA) for implementing intensity modulated radiation therapy (IMRT) clinically, report OA procedures peformed for one patient with prostate cancer. Materials and methods : $P^3IMRT$ (ADAC) and linear accelerator (Siemens) with multileaf collimator are used to implement IMRT. At first, the positional accuracy, reproducibility of MLC, and leaf transmission factor were evaluated. RTP commissioning was peformed again to consider small field effect. After RTP recommissioning, a test plan of a C-shaped PTV was made using 9 intensity modulated beams, and the calculated isocenter dose was compared with the measured one in solid water phantom. As a patient-specific IMRT QA, one patient with prostate cancer was planned using 6 beams of total 74 segmented fields. The same beams were used to recalculate dose in a solid water phantom. Dose of these beams were measured with a 0.015 cc micro-ionization chamber, a diode detector, films, and an array detector and compared with calculated one. Results : The positioning accuracy of MLC was about 1 mm, and the reproducibility was around 0.5 mm. For leaf transmission factor for 10 MV photon beams, interleaf leakage was measured $1.9\%$ and midleaf leakage $0.9\%$ relative to $10\times\;cm^2$ open filed. Penumbra measured with film, diode detector, microionization chamber, and conventional 0.125 cc chamber showed that $80\~20\%$ penumbra width measured with a 0.125 cc chamber was 2 mm larger than that of film, which means a 0.125 cc ionization chamber was unacceptable for measuring small field such like 0.5 cm beamlet. After RTP recommissioning, the discrepancy between the measured and calculated dose profile for a small field of $1\times1\;cm^2$ size was less than $2\%$. The isocenter dose of the test plan of C-shaped PTV was measured two times with micro-ionization chamber in solid phantom showed that the errors upto $12\%$ for individual beam, but total dose delivered were agreed with the calculated within $2\%$. The transverse dose distribution measured with EC-L film was agreed with the calculated one in general. The isocenter dose for the patient measured in solid phantom was agreed within $1.5\%$. On-axis dose profiles of each individual beam at the position of the central leaf measured with film and array detector were found that at out-of-the-field region, the calculated dose underestimates about $2\%$, at inside-the-field the measured one was agreed within $3\%$, except some position. Conclusion : It is necessary more tight quality control of MLC for IMRT relative to conventional large field treatment and to develop QA procedures to check intensity pattern more efficiently. At the conclusion, we did setup an appropriate QA procedures for IMRT by a series of verifications including the measurement of absolute dose at the isocenter with a micro-ionization chamber, film dosimetry for verifying intensity pattern, and another measurement with an array detector for comparing off-axis dose profile.

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Grain-Size Trend Analysis for Identifying Net Sediment Transport Pathways: Potentials and Limitations (퇴적물 이동경로 식별을 위한 입도경향 분석법의 가능성과 한계)

  • Kim, Sung-Hwan;Rhew, Ho-Sahng;Yu, Keun-Bae
    • Journal of the Korean Geographical Society
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    • v.42 no.4
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    • pp.469-487
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    • 2007
  • Grain-Size Trend Analysis is the methodology to identify net sediment transport pathways, based on the assumption that the movement of sediment from the source to deposit leaves the identifiable spatial pattern of mean, sorting, and skewness of grain size. It can easily be implemented with low cost, so it has great potentials to contribute to geomorphological research, whereas it can also be used inadequately without recognition of its limitations. This research aims to compare three established methods of grain-size trend analysis to search for the adequate way of application, and also suggest the research tasks needed in improving this methodology 1D pathway method can corporate the field experience into analyzing the pathway, provide the useful information of depositional environments through X-distribution, and identify the long-term trend effectively. However, it has disadvantage of the dependence on subjective interpretation, and a relatively coarse temporal scale. Gao-Collins's 2D transport vector method has the objective procedure, has the capability to visualize the transport pattern in 2D format, and to identify the pattern at a finer temporal scale, whereas characteristic distance and semiquantitative filtering are controversial. Le Roux's alternative 2D transport vector method has two improvement of Gao-Collins's in that it expands the empirical rules, considers the gradient of each parameters as well as the order, and has the ability to identify the pattern at a finer temporal scale, while the basic concepts are arbitrary and complicated. The application of grain sire trend analysis requires the selection of adequate method and the design of proper sampling scheme, based on the field knowledge of researcher, the temporal scale of sediment transport pattern targeted, and information needed. Besides, the relationship between the depth of sample and representative temporal scale should be systematically investigated in improving this methodology.

Baseline Model Updating and Damage Estimation Techniques for Tripod Substructure (트라이포드 하부구조물의 기저모델개선 및 결함추정 기법)

  • Lee, Jong-Won
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.6
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    • pp.218-226
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    • 2020
  • An experimental study was conducted on baseline model updating and damage estimation techniques for the health monitoring of offshore wind turbine tripod substructures. First, a procedure for substructure health monitoring was proposed. An initial baseline model for a scaled model of a tripod substructure was established. A baseline model was updated based on the natural frequencies and the mode shapes measured in the healthy state. A training pattern was then generated using the updated baseline model, and the damage was estimated by inputting the modal parameters measured in the damaged state into the trained neural network. The baseline model could be updated reasonably using the effective fixity model. The damage tests were performed, and the damage locations could be estimated reasonably. In addition, the estimated damage severity also increased as the actual damage severity increased. On the other hand, when the damage severity was relatively small, the corresponding damage location was detected, but it was more difficult to identify than the other cases. Further studies on small damage estimation and stiffness reduction quantification will be needed before the presented method can be used effectively for the health monitoring of tripod substructures.

A Evaluation of Emergency Braking Performance for Electro Mechanical Brake using Interior Permanent Magnet Synchronous Motor (매입형 영구자석 동기전동기를 적용한 전기기계식 제동장치의 비상제동 성능평가)

  • Baek, Seung-Koo;Oh, Hyuck-Keun;Park, Joon-Hyuk;Kim, Seog-Won;Kim, Sang-soo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.6
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    • pp.170-177
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    • 2020
  • This study examined the clamping force control method and the braking performance test results of an electromechanical brake (EMB) using braking test equipment. Most of the studies related to EMBs have been carried out in the automotive field, dealing mainly with the static test results for various control methods. On the other hand, this study performed a dynamic performance evaluation. The three-phase interior permanent magnet synchronous motor (IPMSM) was applied to drive the actuator of the EMB, and the analysis was verified by JMAG(Ver. 18.0), which is finite element method (FEM) software. The current control, speed control, and position control were used for clamping force control of the EMB, and the maximum torque per ampere (MTPA) control was applied to the current controller for efficient control. The EMB's emergency braking deceleration performance was tested in the same way as conventional pneumatic brake systems when the wheel of a train rotates at 110 km/h, 230 km/h, and 300 km/h. The emergency braking time, with the wheel stopped completely at the maximum rotational speed, was approximately 73 seconds. The similarity of the braking time and deceleration pattern was verified through a comparison with the performance test results of the pneumatic brake system applied to the next generation high-speed railway vehicle (HEMU-430X).

Pulmonary Vessel Extraction and Nodule Reclassification Method Using Chest CT Images (흉부 CT 영상을 이용한 폐 혈관 추출 및 폐 결절 재분류 기법)

  • Kim, Hyun-Soo;Peng, Shao-Hu;Muzzammil, Khairul;Kim, Deok-Hwan
    • Journal of the Institute of Electronics Engineers of Korea CI
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    • v.46 no.6
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    • pp.35-43
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    • 2009
  • In the Computer Aided Diagnosis(CAD) System, the efficient way of classifying nodules from chest CT images of a patient is to perform the classification of the remaining part after the pulmonary vessel extraction. During the pulmonary vessel extraction, due to the small difference between the vessel and nodule features in imaging studies such as CT scans after having an injection of contrast, nodule maybe extracted along with the pulmonary vessel. Therefore, the pulmonary vessel extraction method plays an important role in the nodule classification process. In this paper, we propose a nodule reclassification method based on vessel thickness analysis. The proposed method consist of four steps, lung region searching step, vessel extraction and thinning step, vessel topology formation and correction step and the reclassification of nodule in the vessel candidate step. The radiologists helped us to compare the accuracy of the CAD system using the proposed method and the accuracy of general one. Experimental results show that the proposed method can extract pulmonary vessels and reclassify false-positive nodules accurately.

A Study on Plan for Introduction of Fire Influence Evaluation System through Risk Assessment of the Urban Lifestyle Housing Buildings (도시형 생활주택의 위험성 분석을 통한 화재영향성평가제도의 도입방안에 관한 연구)

  • Kim, Dong-Wook;Baek, Sona;Choi, Jun-Ho
    • Fire Science and Engineering
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    • v.31 no.1
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    • pp.10-17
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    • 2017
  • Securing fire safety using only fire-fighting facilities is difficult because causes of modern fire vary, such as architectural structures and building use patterns. In order for fire safety to be guaranteed by enacting and revising fire regulations reflecting the fire hazard characteristics and user's characteristics, the introduction of fire influence evaluation (fire risk assessment) system needs to be considered in a timely manner to be adopted but unfortunately two attempts before have failed. In this study, a fire case of urban lifestyle housing was surveyed to introduce a fire influence evaluation system and a field survey on the actual condition of the 414 urban lifestyle housing buildings and fire & evacuation simulation results of one representative building in Suyoung-gu and Nam-gu District of Busan Metropolitan City were analyzed. The necessity, procedures and implementation method of fire influence evaluation system were questioned and tested by the professional fire experts, fire officers and firefighters and architects. On the basis of these facts, introduction of (fire influence evaluation system) should be absolutely adopted and the fire department and fire regulation are eligible to implement the system. Therefore, fire regulation needs to be enacted or revised in accordance with the new fire environment and fire safety system that needs to be built up. Accordingly, aggressive promotion through public hearings on the necessity of fire impact assessments, consensus among departments and fostering experts to carry out fire influence evaluation system will be the core.

Dynamic Spectrum Sensing and Channel Access Mechanism in Frequency Hopping Based Cognitive Radio Ad-hoc Networks (주파수 홉핑 기반 인지무선 애드 혹 네트워크에서 동적 스펙트럼 센싱 및 채널 엑세스 방안)

  • Won, Jong-Min;Yoo, Sang-Jo;Seo, Myunghwan;Cho, Hyung-Weon
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.40 no.11
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    • pp.2305-2315
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    • 2015
  • Frequency resource value is growing more and more with the development of the wireless communication. With the advent of the current information society comes a serious shortage of frequency resource, as the amount of supply is far from meeting its demands. Thus, cognitive radio (CR) technique is receiving more attention as a way to make use of the temporarily unoccupied frequency resource. In this paper we propose a novel out-of-band spectrum sensing and dynamic channel access scheme for frequency hopping-based cognitive radio ad-hoc networks. At the beginning of each current channel hopping time, member nodes perform spectrum sensing for the next hopping channel. Based on the proposed collision free primary detection notification, member nodes can determine whether they should execute a hopping time extension procedure of the current channel or not. When the primary detected hopping channel is re-idled, the hopping pattern recovery procedure is performed. In this paper we evaluated the performance of the proposed dynamic sensing and hopping channel extension mechanism for the various wireless network conditions. As a result, we show that the proposed method can increase channel utilization and provide reliable channel management operation.

The Instrumental Development for Pulling.Reaping Training & Measuring in Judo (유도 당기기.후리기 훈련 및 측정 장비 개발)

  • Kim, Eui-Hwan;Choi, Eun-Soo;Nam, Duck-Hyun;Kim, Sung-Sup;Chung, Jae-Wook;Kim, Tae-Whan
    • Korean Journal of Applied Biomechanics
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    • v.18 no.1
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    • pp.213-226
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    • 2008
  • E. H. KIM, E. S. CHOI, D, H. NAM, S. S. KIM, J. W. CHUNG and T. W. KIM, The Instrumenfal Development for Pulling . Reaping Training & Measuring in Judo.Korean Jiurnal of Sport Biomechanics, Vol. 18, No. 1, pp. 213-226, 2008. The purpose of this study was to develop a judo-doll uke(partner : doll-uke) for training and measurement applicable to pulling, pushing and reaping in judo. In Judo the most common techniques consist of the pulling, pushing and sweep which all need to be practiced with a partner. So the research needs to develop a measurement system that can be used to evaluate the forces involved with these techniques. Also the Doll-Uke must be developed so that judokas can train alone. After the manufacture of Doll-Uke the usefulness of it must be evaluated. The height of a Doll-Uke is l70cm and its weight is 50kg. Doll-Uke was developed with a trunk angle of 55 and the lower extremities of an angle of 45. The Doll-Uke can also measure the forces developed during the pulling, pushing and sweep. Due to the ability of the system to measure the forces while preforming Judo techniques feedback can be provided to the Judokas to improve their performance.

Effect of Climate Factors on Tree-Ring Growth of Larix leptolepis Distributed in Korea (기후인자가 일본잎갈나무의 연륜생장에 미치는 영향 분석)

  • Lim, Jong Hwan;Sung, Joo Han;Chun, Jung Hwa;Shin, Man Yong
    • Journal of Korean Society of Forest Science
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    • v.105 no.1
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    • pp.122-131
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    • 2016
  • This study was conducted to analyze the effect of climatic variables on tree-ring growth of Larix leptolepis distributed in Korea by dendroclimatological method. For this, annual tree-ring growth data of Larix leptolepis collected by the $5^{th}$ National Forest Inventory were first organized to analyze yearly growth patterns of the species. To explain the relationship between tree-ring growth of Larix leptolepis and climatic variables, monthly temperature and precipitation data from 1950 to 2010 were compared with tree-ring growth data for each county. When tree-ring growth data were analyzed through cluster analysis based on similarity of climatic conditions, six clusters were identified. In addition, index chronology of Larix leptolepis for each cluster was produced through cross-dating and standardization procedures. The adequacy of index chronologies was tested using basic statistics such as mean sensitivity, auto correlation, signal to noise ratio, and expressed population signal of annual tree-ring growth. Response function analysis was finally conducted to reveal the relationship between tree-ring growth and climatic variables for each cluster. The results of this study are expected to provide valuable information necessary for estimating local growth characteristics of Larix leptolepis and for predicting changes in tree growth patterns caused by climate change.