• Korean Journal of Biological Psychiatry
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• v.20 no.3
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• pp.104-110
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• 2013

Objectives : The aim of this study was to examine the prospective impact of the apolipoprotein E (APOE) ${\varepsilon}4$ on cognitive performance in the community-dwelling elderly individuals with Alzheimer's disease (AD). Methods : The total number of subjects was 30 (12 men and 18 women) who were diagnosed with AD from a Korean project of "Early Detection of Dementia". People aged 65-85 years were included in the analysis. The eight neuropsychological domains from the Korean version of Consortium to Establish a Registry of Alzheimer's Disease (CERAD-K) were conducted to test subjects. They have been followed at 24-month intervals with the same assessments at each interval. Their cognitive performance at 2 year intervals was compared by the occurrence of the APOE ${\varepsilon}4$. Results : The impact of ${\varepsilon}4$ allele was significant in the Word List Memory Test (WLMT, F = 4.345, df = 1, p = 0.021) and Word List Recall Test (WLRT, F = 5.569, df = 1, p = 0.033). Conclusions : The APOE ${\varepsilon}4$ allele was significantly correlated especially with verbal episodic memory domain in community-dwelling elders diagnosed with AD.

• Clinical and Experimental Pediatrics
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• v.52 no.3
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• pp.324-329
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• 2009

Purpose : Acute interstitial pneumonia (AIP) is a rare disease, but its prognosis is fatal because of lack of efficient treatment modality. Recently, it has been reported that there was epidemic AIP in Korea. This study aims to investigate the past and current status of AIP in Korea. Methods : We performed a nationwide survey and a prospective study. From August 6 to 15, 2008, a questionnaire survey was conducted to identify the prevalence, local distribution, and response to current treatments. The questionnaire was answered by pediatrician working in 23 referral centers in Korea. In addition, 5 referral centers in Seoul performed a preliminary prospective observational study by obtaining clinical data and specimens from appropriate patients. The Korea Centers for Disease Control and Prevention analyzed the samples for possible pathogens. Results : The survey showed 78 AIP cases had occurred and 36 patients had died. Lung biopsy was performed only on 20 patients. In 2008, 9 AIP cases developed. In a prospective study, 9 (M:F=5:4) patients developed AIP in spring and 7 (78%) died, with the mean rate of death occurring 46 days after diagnosis. Human corona virus 229E, cytomegalovirus, influenza A virus, influenza B virus, and parainfluenza virus were isolated from the respiratory specimens. Conclusion : This study showed nationwide prevalence of AIP in Korea. In addition, because of the high mortality rate and rapid progress, pediatricians need to be aware of the disease. Further studies and a nationwide network are required for reducing the morbidity and mortality rates related to AIP.

• Journal of the Korean Arthroscopy Society
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• v.12 no.2
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• pp.91-92
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• 2008

후방십자인대 및 후외측인대 재건술 후 결과는 많은 발전이 있었지만, evidence medicine의 측면에서 재활 방법에 관한 전향적 연구는 없다. 현재까지의 재활 방법은 다양하게 소개되었지만 전방십자인대 재건술처럼 가속 재활을 하는 것은 바람직스럽지 않다. 후방십자인대, 후외측인대 그리고 다발성 인대 재건술 후 재활은 수술 방법과 환자의 재건된 인대의 상태, 하지 정렬 등에 따라서 개별화하여 점진적으로 진행하여야 할 것이고, 재활기간 동안 의사의 세심한 관찰이 필요하다.

• 대한관절경학회:학술대회논문집
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• 2008.04a
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• pp.84-85
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• 2008

후방십자인대 및 후외측인대 재건술 후 결과는 많은 발전이 있었지만, evidence medicine의 측면에서 재활 방법에 관한 전향적 연구는 없다. 현재까지의 재활 방법은 다양하게 소개되었지만 전방십자인대 재건술처럼 가속 재활을 하는 것은 바람직스럽지 않다. 후방십자인대, 후외측인대 그리고 다발성 인대 재건술 후 재활은 수술 방법과 환자의 재건된 인대의 상태, 하지 정렬 등에 따라서 개별화하여 점진적으로 진행하여야 할 것이고, 재활기간 동안 의사의 세심한 관찰이 필요하다.

• 대한임상약리학회:학술대회논문집
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• 1999.12a
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• pp.40-40
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• 1999

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.16 no.1
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• pp.124-131
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• 2005

Childhood and adolescent onset-bipolar disorders have higher rate of comorbidity with anxiety disorders as well as attention deficit hyperactivity disorder and conduct disorder. Obsessive compulsive disorder, social phobia, panic disorder, and separational anxiety disorder are common comorbid anxiety disorders with bipolar disorders in child and adolescent. Prospective and reliable data on temporal and causal relationship between the onset of bipolar disorders and the onset of comorbid anxiety disorders are still in debate. The authors report 2 adolescent cases with antidepressant induced-manic episodes with preceding anxiety symptoms. The authors suggest careful prescription of antidepressants for anxiety disorders, even for those who do not have definite past history or family history of bipolar disorders. Further comprehensive and prospective studies are requested for the temporal relationship and pharmacological guideline for comorbid bipolar disorders and anxiety disorder in child and adolescent.

• Journal of the Korea Convergence Society
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• v.10 no.9
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• pp.99-110
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• 2019

The purpose of this study was to investigate the comparison between metabolic syndrome indicators and nutrient intakes in Korean menopausal women from the Korean National Health and Nutrition Examinations Survey data (2010~2012). Menopausal Status were classified into premature menopause(n=214) and natural menopause(n=2,546). Among the nutrient groups, retinol intake was a significant factor in natural menopausal women according to BMI levels and riboflavin intake was another significant factor in premature menopausal women according to fasting glucose levels. The results suggested that micronutrient including retinol, riboflavin, fiber and calcium were significantly associated with metabolic syndrome risk in Korean postmenopausal women. Further research is required for elucidating the association between nutrient intakes and incidence of metabolic syndrome in postmenopausal women within a large population in prospective studies.

• Clinics in Shoulder and Elbow
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• v.12 no.1
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• pp.21-26
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• 2009

Purpose: The aim of this study was to examine the dose-related effect of extracorporeal shock wave therapy (ESWT) for lateral epicondylitis. Materials and methods: Thirty patients with refractory lateral epicondylitis despite conservative treatment for 6 months were enrolled in this study. The patients were divided randomly into a low- and high-energy group. All patients were treated 3 times with ESWT with an interval of 1 week in a double blinded manner. The mean energy level in the low- and high-energy group was $0.12 mJ/mm^2$ and $0.24 mJ/mm^2$, respectively. The upper extremity functional scales and Mayo elbow scores were measured prospectively at the baseline, 1, 3 and 6 months after ESWT. Results: Significant clinical improvement was observed in both groups after ESWT. The high-energy group showed better pain improvement at 6 months after ESWT (p=0.019). The effect of ESWT was dominant between 1 and 6 months after ESWT than within 1 month. Conclusion: ESWT for lateral epicondylitis demonstrated showed good results regardless of the energy dose. However, a high-energy level was more effective in pain improvement after 6 months of treatment.

• Journal of Teachers' Pension
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• v.1
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• pp.91-127
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• 2016

노후의 경제적 안정이 사회적으로 강조되고 있는 상황에서 2015년 사립학교교직원연금법(사학연금법)이 연금지급개시 연령의 연장과 함께 부담률 인상 및 지급률의 인하를 주된 내용으로 개정되어 사립학교교직원연금(사학연금) 가입자의 소득공백기 발생과 전반적인 소득대체율 하락이 두드러진 문제로 나타나고 있다. 이와 같은 상황에서 사학연금 가입자가 재직 시 소득, 퇴직 시 자산 및 퇴직수당, 그리고 연금급부 등의 활용 가능한 재원을 통해 퇴직 후 소득의 안정을 이룰 수 있는 방안을 다양한 사적연금과의 연계 측면에서 살펴보았다. 한편 사립학교교직원연금공단(사학연금공단)의 업무범위가 법으로 정해져 있기 때문에 새롭거나 필요한 업무를 자유의사에 따라 추진할 수 없는 상황이다. 따라서 사학연금법에 제시되어 있는 사학연금공단 업무에 대한 전향적인 해석을 통해 사학연금 가입자에 대한 생애자산관리서비스의 제공 가능성에 대해서 살펴보았다. 생애자산관리서비스는 사학연금법의 개정으로 인해 가입자가 겪게 되는 소득공백기 및 소득 대체율 하락 문제를 보다 포괄적으로, 그리고 장기적인 관점에서 접근하여 궁극적으로는 퇴직 후 경제적 안정을 지원할 수 있는 방안이라고 판단된다.

• Environmental engineer
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• v.24 s.256
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• pp.23-25
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• 2007

건강영향의 중요성에 대한 인식이 증가함에 따라, 본 연구는 건강영향평가의 최적 도입방안을 연구하는데 목적을 둔다. 한국의 지난 30년 동안 환경영향평가(EIA)를 수행하고 있다. EIA내의 스크리닝, 스코핑, 분석, 영향평가, 협의, 보고서 검토, 의사결정 및 모니터링 과정들은 HIA의 필수적인 부분이 될 것이다. 스크리닝 및 스코핑 과정은 아직 EIA내에 포함되어 있지는 않지만, 기존 EIA 과정내로 HIA를 통합하는 것은 한국에서 매우 효율적인 방안이 될 수 있다. 나아가, EIA내의 기존 공중-위생 항목을 보건 영향을 고려하기 위해 충분한 결정인지를 지닌 환경-보건항목으로 교체 및 확장하는 것이 바람직할 것이다. 한국의 경우, HIA의 초기 시행을 고려할 때 사회과학 및 심리학에 기초한 전향적 및 정량적 접근법이 보다 적합할 것이다. 본 연구에서는, 체크리스트와 툴키트가 개발되었으며, HLA의 적용 및 보급에 있어 매우 유효한 지침이 될 수 있을 것이다.