• Radiation Oncology Journal
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• v.25 no.4
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• pp.219-226
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• 2007

Purpose: The aim of this retrospective analysis was to analyze the results of radiotherapy administered to patients with neck node metastases from an unknown primary cancer, with or without neck dissection. Materials and Methods: From January 1986 to December 2005, 88 patients with neck node metastases from an unknown primary cancer were treated with curative intent. The age of the patients ranged from 35 to 74 years (median age, 59 years). There were 74 male and 14 female patients. Distribution of patients by N status was as follows: N1, 4 patients; N2a, 10 patients; N2b, 48 patients; N2c, 8 patients; N3, 18 patients. Fifty-one patients underwent neck dissection and 37 patients had only a biopsy (31 patients had fine-needle aspiration and 6 patients had an excisional biopsy). All patients received radiotherapy. The follow-up time ranged from 1 to 154 months, with a median time of 32 months. Results: The overall survival (OS) and disease-free survival (DFS) rate at 5 years were 43.9% and 41.7%, respectively. The factors associated with the OS rate were neck dissection, and a subsequent primary tumor. Factors associated with the DFS rate were N stage, neck dissection, and a subsequent primary tumor. Neck failure was noted in 15 patients, distant metastases in 18 patients, and a subsequent primary tumor in 8 patients. Conclusion: With comprehensive radiotherapy given to the bilateral neck and the potential mucosal sites, good survival rates can be obtained in patients with neck node metastases from an unknown primary cancer. However, considering the side effects, a randomized trial is required to determine the optimal radiotherapy volume.

• Radiation Oncology Journal
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• v.26 no.1
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• pp.45-55
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• 2008

Purpose: This study evaluates the association of estrogen receptor(ER), progesterone receptor(PR), Her-2, COX-2, and survivin with the clinicopathological features and outcomes in young Korean women with breast cancer using recently developed tissue microarray(TMA) technology. Materials and Methods: A cohort of 212 young patients with breast cancer diagnosed at the age of 45 years or younger from March 1994 to August 2005, were enrolled in this study. The age range of patients was $23{\sim}45$ years(median age, 39 years). The minimum and median follow-up periods were 24 months and 60 months, respectively. Serial sections of primary tumors were processed by the use of a TMA for immunohistochemical staining for five biomarkers. The correlation of these five biomarkers and the clinicopathological features and outcomes were analyzed by statistical methods. Results: The majority of the patients were stage T1(90 patients) or T2(101 patients), and 105 patients(49.5%) had an axillary node metastasis. The 5-year overall and relapse free survival rates for all of the patients were 90.4% and 82.3%, respectively, and 36 patients had a locoregional or distant metastasis as a first event. Positive expression of ER, PR, Her-2, COX-2, and survivin was determined in 38.2%, 45.3%, 25.9%, 41.5%, and 43.4%, of the tumor samples, respectively. Tumor stage, nodal status, age, as well as expression of ER, PR, and HER-2 status were significantly associated with the disease free survival rate. Tumor stage, nodal status, as well as expression of ER, PR, and HER-2 were significantly related with the overall survival rate. Expression of COX-2 and survivin were not single independent prognostic factors for the disease free and overall survival rate although co-expression of HER-2 and COX-2 had a tendency as a poor prognostic factor. By multivariate analysis, only T stage and lymph node status were significant prognostic factors, and ER status was a marginally significant prognostic factor(p=0.075). Conclusion: Expression of ER, PR and HER-2 were significant prognostic factors for the relapse free and overall survival rate. Expression of COX-2 and survivin were not prognostic factors for young women with breast cancer.

• Radiation Oncology Journal
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• v.17 no.3
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• pp.187-194
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• 1999

Purpose : The aim of this study is to look for the possible efficacy of external irradiation for locally advanced papillary thyroid cancers (stage pT4 or Nl ). Methods and Materials : From August 1981 through September 1997, 91 Patients with locally advanced papillary thyroid cancers (stage pT4 or Nl ) have been treated with external irradiation and followed up at our clinic. All of the patients have been treated with surgical resection. After surgery, 23 patients received postoperative external irradiation with or without ablative radioiodine therapy, whereas the other 68 patients were treated with ablative radioiodine therapy alone. Distributions of sex, age, and stage were comparable in both irradiated and nonirradiated groups. Multivariate analysis of the influence by age, sex, stage, ablative radioiodine therapy and external irradiation on local control were peformed by using Cox's proportional hazard model. Results : Overall survival rates at 7 years were of no significant difference in both groups. There were $98.1\%$ for no RT group and $90\%$ for RT group (p=0.506). 5-year local control rates were significantly different, these were $95.2\%$ for RT group and $67.5\%$ for no RT group (p=0.0408). An analysis of the prognostic factors, age, sex, stage, and RAI were not significant variables, except for the external irradiation. Conclusion : Adjuvant postoperative external irradiation did not affect overall survival, but significantly improved local control in the patients with locally advanced papillary thyroid cancers (stage pT4 or lympy node involvement).

• Applied Chemistry for Engineering
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• v.2 no.4
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• pp.311-329
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• 1991

Electrochemical behavior of surface active Osmium bipyridine complex adsorbed in a monomolecular layer on tin oxide electrodes by the Langmuir-Blodgett method was studied. Theoretical equation of cyclic voltammetry of electrode reactions for redox species adsorbed as monolayer form was discussed by reversible and quasi-reversible waves. The film was transferred onto the $SnO_2$ electrode surface and then amounts of charge on the electrode were measured in the technique of cyclic voltammetry. The electron transfer mediation of these monolayer with $Fe^{2+}$, TEMPOL and others were studied. And the cyclic voltammetry were simulated by taking into account the interaction parameters. From these values, we found it possible to fit almost all measured cyclic voltammograms with these parameters. The recent works and directions using LB method were introduced with various applicable field.

• Annual Conference on Human and Language Technology
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• 1994.11a
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• pp.297-304
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• 1994

코퍼스는 기계 가독형으로 개장되어 있는 실제 사용 언어의 집합으로 자연어 처리에 필요한 여러 가지 언어 정보를 내재하고 있다. 이들 정보는 코퍼스 분석기를 이용하여 획득할 수 있으며 용례와 각종 통계 정보 및 확률 정보, 연어 목록 등은 코퍼스에서 추출할 수 있는 대표적인 언어 정보들이다. 그러나 기존의 한국어 코퍼스 분석 도구들은 용례 추출 기능만을 보유하여 활용 범위가 제한되어 있었다. 이에 본 논문에서는 대량의 한국어 코퍼스를 분석하여 용례뿐만 아니라 자연어 처리의 제분야에서 필요한 언어 정보들을 추출하는 방법에 대해 연구하였으며 이의 검증을 위해 KCAT(Korean Corpus Analysis Tool)를 구현하였다. KCAT는 코퍼스 색인, 용례 추출, 통계 정보 추출, 연어 추출 부분으로 구성되어 있다. 용례 색인을 위해서는 여러 가지 사전과 용례 색인 구조가 필요한데 KCAT에서는 가변 차수 B-Tree 구조를 이용하여 사전을 구성하며 용례 색인을 위해 버킷 단위의 역 화일 구조를 이용한다. 질 좋은 용례의 추출을 위해 KCAT는 다양한 용례 연산 및 정렬 기능을 제공한다. 또한 통계적 방법의 자연어 처리 분야를 위해 어휘 확률, 상태 전이 확률, 관측 심볼 확률, 상호 정보, T-score 등을 제공하며, 기계 번역 분야에서 필요한 연어를 추출한다.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.33 no.2
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• pp.609-617
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• 2013

The objective of this study was to evaluate the oxidation method to remove endocrine disrupting chemicals in reverse osmosis(RO) retentate for the reuse of wastewater effluent. Oxidation of organic pollutants was induced by the persulfate catalyzed by Fe(II). Affecting factors such as initial pH and ionic strength on the Fe(II) catalyzed persulfate oxidation were evaluated. $17{\alpha}$-ethynylestradiol (EE2) degradation efficiency decreased as pH and ionic strength increased. However, the efficiency increased as chloride ion concentration increased due to the influence of radical transfer.

• Proceedings of the KIEE Conference
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• 2003.07c
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• pp.1809-1811
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• 2003

Oil-TR에서의 이상을 진단하기 위해서, 유중가스 분석 및 AE센서를 사용한 부분방전측정을 중심으로 많은 연구가 진행/적용되어왔다. 근래 들어서는 거의 모든 진단항목이 환선상태에서 측정하는 것으로 전이되는 추세이며, 사용자가 설비의 현재의 상태를 계속 감시하여 수명을 연장시키는데 관심의 초점이 모아지고 있다. 이에 본 논문에서는 Spiral-Type의 광대역 UHF센서를 사용하여 TR에서 발생하는 부분방전을 측정하였다. 이 방식은 TR내부에 센서를 주입하는 방식으로서, 상대적으로 감도가 우수하며, 노이즈의 영향이 적게 받는다. 코로나방전, 표면방전 및 부유물 형태의 결함에 대하여 측정한 결과를 나타내었으며, 주파수 분포에 대한 변화를 주로 관측하였다. 결과적으로, 서로 다른 결함은 서로 다른 결과를 나타내었으며, 이를 바탕으로 Oil-TR에서 발생하는 결함을 인식할 수 있는 데이터로 활용할 수 있다.

• Korean Journal of Applied Biomechanics
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• v.13 no.1
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• pp.185-204
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• 2003

The purpose of this study was to obtain the data for stable and accurate techniques of the free throw in basketball. The subjects of this study were seven male basketball player consisted of college students athletes. Free throw motions were taken by video camera. The three-dimensional coordinates was processed by DLT. The variables were the velocity, the angular velocity of the upper extremity segments, degree, and angular momentum. The result of analysis is summarized as follows. 1. The velocity and angular velocity of the upper extremity segment was showed an gradual increase and a smooth velocity transfer, transferring from proximal segment to distal segment at free throw motion in basketball. 2. The local term and remote term angular velocity momentum of the proximal segment showed larger than that of the distal segment in X, Y, Z axis component all. 3. The remote term angular momentum was showed larger than that of the local term angular momentum in X, Y, Z axis component all. 4. The angular motion of the upper trunk and upper arm, upper arm and forearm was showed in opposite direction and symmetrical angular momentum in local term angular momentum of the Y and Z axis component. 5. All the segments of upper extremity segment was showed left rotation in remote term angular momentum of the Y axis component and right rotation in remote term angular momentum of the Z axis component.

• Proceedings of the Korea Water Resources Association Conference
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• 2016.05a
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• pp.551-551
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• 2016

북한과의 대표적 공유하천인 임진강 유역은 유역의 2/3를 차지하고 있는 북한지역내에서 신뢰할만한 강우 및 수문관련 정보에 접근할 수 없는 문제점이 존재한다. 또한, 임진강 중류에는 북한에서 운영하는 황강댐의 예고없는 수문운영에 따라 수시로 하류 홍수피해가 발생할 수 있는 상황이며, 이에 대비하여 우리나라에는 군남 홍수조절지를 건설하여 운영하고 있다. 하지만 임진강 상류에 대한 수문정보를 취득하기 어렵기 때문에 가까운 수위관측소의 수위변화와 저류함수 모형 등을 이용하여 댐 운영을 실시하고 있는 것이 현실이다. 본 연구에서는 미계측유역에서의 수문정보를 확보하기 위한 목적으로 레이다강우 등 원격탐사정보와 분포형 강우-유출모형을 이용하여 황강댐 유입량을 산정할 수 있는 수문모형을 구축하였다. 황강댐유역의 수문모형 실매개변수를 보정하기 어렵기 때문에 인근 한탄강댐유역의 매개변수를 지역화를 통하여 전이하여 활용하였다. 산정된 수문곡선은 동시간대 한탄강댐 유입량의 면적비적용, 강수의 공간전이후 산정된 한탄강댐 유입량의 면적비적용등의 다양한 시나리오에서 모의된 수문곡선과의 비교를 수행하여 본 기법의 타당성을 입증하고자 시도하였다. 또한 군남홍수조절지 유입수문곡선과의 비교를 통하여 황강댐과 4월 5일댐의 수문운영현황 및 잔유역유입량을 역추정코자 하였다.

• Korean Public Administration Review
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• v.47 no.1
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• pp.201-237
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• 2013

본 연구는 효율적 인적자원관리의 실행과 유지에 있어서 '일과 삶 균형(WLB: Work-Life Balance)' 정책의 중요성을 이론적·실증적 접근방식으로 규명하고자 하였다. 특히 본 연구에서는 WLB 정책을 유연근무제, 친가족정책, 개인신상지원 프로그램 등 3가지 차원으로 구분하여 제시하였으며, 분석대상을 공공조직과 민간조직으로 구분하여 기존 연구와의 차별화를 도모하였다. 연구모형 개발과 가설검증을 위해 제3차 여성가족패널(KLoWF) 자료를 바탕으로 WLB 정책과 정책 부합성, 직무만족도, 이직의도 간의 관계를 분석하였으며, 설문조사를 통한 양적 분석의 한계를 보완하기 위하여 공공조직 및 민간조직 여성 근로자와의 심층 인터뷰를 통한 질적 분석을 병행하였다. 분석결과, WLB 정책과 조직 효과성 간의 관계에 있어 공공조직과 민간조직 간의 유의미한 차이가 있음을 확인할 수 있었으며 심층 인터뷰를 통해 이러한 결과가 공공조직과 민간조직의 상호 이질적인 조직 문화, 제도, 구조적 특성에 기인하고 각 영역 구성원들의 서로 다른 욕구 및 동기 유발 체계에 의한 것임을 발견할 수 있었다. 이러한 분석결과를 바탕으로 본 연구에서는 각각의 조직 특성에 맞는 수요자 친화형 WLB 정책 구축의 필요성을 제안하고, WLB 정책 시행 측면의 문제점 및 개선방안 등을 제시하였다.