• Korean Journal of Otorhinolaryngology-Head and Neck Surgery
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• v.60 no.10
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• pp.504-511
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• 2017

Background and Objectives In this study, we evaluated differences in the prevalence of allergic rhinitis, asthma, atopic dermatitis and specific immunoglobuline E (IgE) value for some respiratory antigens in Korean adults. Subjects and Method The study was conducted using data from the 5th National Health and Nutrition Survey (2010-2012). All subjects who were aged 19 years or older completed questionnaires on asthma, atopic dermatitis and allergic rhinitis. The subjects were first divided into male and female, and then into age groups of 19-29, 30-39, 40-49, 50-59, 60-69, ${\geq}70$ each. The lifetime and current prevalence rates for allergic rhinitis, asthma, and atopic dermatitis were calculated for each age group. The total and specific IgE level for Dermatophagoides farinae (DF), cockroach, and dog dander were also calculated. Results Final participants of 17542 were analyzed for the prevalence rate among the total of 25534 participants. The mean IgE level was calculated from 2028 subjects from the final participants. In asthma, the lifetime prevalence and current prevalence increased with age, but decreased with atopic dermatitis and allergic rhinitis. Total IgE level increased with age, but IgE level of DF reached its peak at 20-29 years, and then decreased rapidly thereafter. There was no clear trend for cockroach and dog dander. Conclusion The prevalence of allergic diseases in adults varies widely by age group. Asthma has a low prevalence after age 20 and gradually increases after age 50. Atopic dermatitis and allergic rhinitis are the most prevalent in their 20s and gradually decrease thereafter.

• Herbal Formula Science
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• v.29 no.1
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• pp.33-44
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• 2021

Renal ischemia-reperfusion injury(IRI), an important cause of acute renal failure (ARF), cause increased renal tubular injury. Jesaeng-sinkihwan (JSH) was recorded in a traditional Chines medical book named "Bangyakhappyeon (方藥合編)". JSH has been used for treatment of diabetes and glomerulonephritis with patients. Here we investigate the effects of Jesaeng-sinkihwan (JSH) in a mouse model of ischemic acute kidney injury. The animals model were divided into four groups at the age of 8 weeks; sham group: C57BL6 male mice (n=9), I/R group: C57BL6 male mice with I/R surgery (n=9), JSH Low group: C57BL6 male mice with surgery + JSH 100 mg/kg/day (n=9) and JSH High group: C57BL6 male mice with surgery + JSH 300 mg/kg/day (n=9). Ischemia was induced by clamping the both renal arteries during 25 min, and reperfusion was followed. Mouse were orally given with JSH (100 and 300 mg/kg/day during 3 days after surgery. Treatment with JSH significantly ameliorates creatinine clearance(Ccr), Creatinine (Cr) and blood urea nitrogen(BUN) in obtained plasma. . Treatment with JSH reduced kidney inflammation markers such as Neutrophil Gelatinase Associated Lipocalin (NGAL) and kidney injury molecule-1 (KIM-1). JSH also reduced the periodic acid schiff (PAS) staining intensity and picro sirius red staining intensity in kidney of I/R group. These findings suggest that JSH ameliorates tubular injury including renal dysfunction in I/R induced ARF mouse.

• The Korean Journal of Oral and Maxillofacial Pathology
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• v.41 no.4
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• pp.155-162
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• 2017

Connective tissue growth factor (CTGF, CCN2) is one of the multi-functional secreted proteins which belong to CCN family of cysteine-rich growth factors. CTGF is known to have pivotal roles in embryonic endochondral ossification but its role in relevance to periodontitis is never been determined. To identify new molecular mediators associated with periodontitis-induced bone resorption, we have analyzed publicly available GEO database and found the markedly augmented CTGF mRNA expression in periodontitis gingival tissues. The existence of CTGF significantly enhanced mature osteoclasts survival which accompanied by reduction in TUNEL-positive nuclei and PARP cleavage. These results may provide another line of evidence the CTGF mediated prolonged osteoclast survival and subsequent increased bone resorption in the periodontitis patients.

• The Korean journal of helicobacter and upper gastrointestinal research
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• v.18 no.4
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• pp.271-274
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• 2018

Ganglioneuroma of the gastrointestinal tract is a rare tumor that consists of ganglion cells, nerve fibers, and supporting cells of the enteric nervous system. Ganglioneuromas are usually associated with genetic disorders such as the multiple endocrine neoplasia syndrome or neurofibromatosis. Ganglioneuromas of the gastrointestinal tract predominantly involve the colon and rectum, and reports about duodenal ganglioneuromas are few. Herein, we report a case of duodenal ganglioneuroma treated with endoscopic resection. A 56-year-old female patient visited our hospital because of a subepithelial tumor in the second portion of the duodenum. She had no remarkable medical or family history and revealed no history of genetic disorders. Endoscopic ultrasonography and abdominal computed tomography revealed a tumor located mainly in the submucosal layer, without any regional lymph node involvement. Endoscopic resection of the lesion was performed, and the pathological examination confirmed a duodenal ganglioneuroma.

• Korean Journal of Acupuncture
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• v.35 no.4
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• pp.226-233
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• 2018

Objectives : The purpose of this study was to establish an accurate and effective method of locating acupoints of the forearm by studying bone proportional measurement. Methods : A total of 60 volunteers, 30 men and 30 women, participated in this study. 7 parts of the body were measured by a soft ruler or digital vernier calipers. The cun of the upper limb was calculated and analyzed. And the results were compared with the standard cun. Results : The bone proportional cun of the forearm based on height and femur was close to 11. It was different from the standard 12.5, 12 or 10. The cun of the forearm by thumb or finger width measurement was different from the standard too. Conclusions : We suggest that locating acupoints of the forearm needs to be done based on 11 cun. The confusion on locating acupoints of the forearm will be reduced by reflecting the result of the actual measurement.

• The Journal of the Korean dental association
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• v.57 no.9
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• pp.529-533
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• 2019

Recently, an advanced workflow has been introduced to finish implant surgery and prosthetic treatment in one-day. However, Because of 1. Patient's physical condition, 2. Surgical technique, 3. Digital technical limitations, the complete completion of one-day implant treatment is practically difficult. Therefore, this paper proposes a "two-days implant digital workflow" that short-time implant surgery and restores prosthetics the next day. Even though it takes more than one day, this workflow is a realistic implant treatment protocol that can reduce the chair time in the clinic.

• Proceedings of the Korea Water Resources Association Conference
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• 2023.05a
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• pp.135-135
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• 2023

우리나라의 전 국토면적 중 약 63% 이상이 산지로 이루어져 있으며 이는 OECD국가 중 4위에 해당할 정도로 매우 높은 비율이다. 광활한 산지 면적의 효율적 이용을 위해 사면개발, 태양광 시설, 관광자원으로써의 활용 등이 이루어져 토양침식에 매우 취약해졌으며, 하천으로의 토사유입량이 증가하고 있다. 따라서 하천으로 유입된 유사량의 조사가 매우 중요하며, 유사량 중 입경이 큰 소류사량을 추정하기 위한 조사 장비 중 간접적 방법인 하이드로폰에 관한 국내·외 연구가 활발히 진행되고 있다. 본 연구에서는 기존 소류사량 추정 방법 중 추정식을 활용한 방법의 추정량이 많아질수록 정확도가 낮아지는 문제를 개선하기 위한 노력으로 인공신경망의 한 종류인 Convolutional Neural Networks(CNN)를 소류사량의 계측에 적용하기 위한 연구를 시도하였으며, 그 결과와 실제 소류사량의 정확도를 비교 및 분석하였다. 실험데이터를 획득하기 위하여 실내수로를 구축하였으며, Labview를 이용하여 소류사량에 대한 충돌음 이미지데이터를 취득한 후 학습을 진행한 결과, 검증데이터에 대한 정확도는 60%이상의 값으로 나타났다. 향후 추가적인 데이터 확보를 통해 정확도 향상을 위한 연구를 진행하고자 한다.

• The Journal of Pediatrics of Korean Medicine
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• v.37 no.2
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• pp.12-27
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• 2023

Objective This study aimed to analyze the efficacy of the tuina treatment for congenital muscular torticollis based on randomized controlled clinical studies in China. Methods The China National Knowledge Infrastructure was the main source of data. Using the keywords "tuina", "chuna", "推拿", and "斜颈", 12 randomized controlled clinical studies were identified and analyzed. Results Compared with the control group, the tuina treatment group showed statistically significant changes with respect to the therapeutic effect. Conclusions This study suggests that tuina treatment is effective for congenital muscular torticollis patients and provides evidence for further studies on oriental medicine treatments, including tuina for congenital muscular torticollis.

• Proceedings of the Korean Society of Computer Information Conference
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• 2021.07a
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• pp.387-390
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• 2021

최근 전자 상거래 시장이 급격한 성장을 이루면서 고객들의 급변하는 니즈를 파악하는 것이 기업들의 수익에 직결되는 요소로 인식되고 있다. 이에 기업들은 고객들의 니즈를 신속하고 정확하게 파악하기 위해, 기축적된 고객 관련 각종 데이터를 활용하려는 시도를 강화하고 있다. 기존 시도들은 주로 구매 행동 예측에 중점을 두었으나 고객 행동의 전후 과정을 해석하는데 있어 어려움이 존재했다. 본 연구에서는 고객이 구매한 상품을 확정 또는 환불하는 행동을 취할 때 해당 행동이 발생하는데 있어 어떤 요소들이 작용하였는지를 파악하고, 어떤 고객이 환불할 지를 예측하는 예측 모형을 새롭게 제시한다. 예측 모형 구현에는 트리 기반 앙상블 방법을 사용해 예측력을 높인 XGBoost 기법을 적용하였으며, 고객 의도에 영향을 미치는 요소들을 파악하기 위하여 대표적인 설명가능한 인공지능(XAI) 기법 중 하나인 SHAP 기법을 적용하였다. 이를 통해 특정 고객 행동에 대한 각 요인들의 전반적인 영향 뿐만 아니라, 각 개별 고객에 대해서도 어떤 요소가 환불결정에 영향을 미쳤는지 파악할 수 있었다. 이를 통해 기업은 고객 개개인의 의사 결정에 영향을 미치는 요소를 파악하여 개인화 마케팅에 사용할 수 있을 것으로 기대된다.

• Proceedings of the Korean Society of Computer Information Conference
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• 2021.07a
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• pp.395-398
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• 2021

최근 방대한 양의 텍스트 정보가 인터넷에 유통되면서 정보의 핵심 내용을 파악하기가 더욱 어려워졌으며, 이로 인해 자동으로 텍스트를 요약하려는 연구가 활발하게 이루어지고 있다. 텍스트 자동 요약을 위한 다양한 기법 중 특히 트랜스포머(Transformer) 기반의 모델은 추상 요약(Abstractive Summarization) 과제에서 매우 우수한 성능을 보이며, 해당 분야의 SOTA(State of the Art)를 달성하고 있다. 하지만 트랜스포머 모델은 매우 많은 수의 매개변수들(Parameters)로 구성되어 있어서, 충분한 양의 데이터가 확보되지 않으면 이들 매개변수에 대한 충분한 학습이 이루어지지 않아서 양질의 요약문을 생성하기 어렵다는 한계를 갖는다. 이러한 한계를 극복하기 위해 본 연구는 소량의 데이터가 주어진 환경에서도 양질의 요약문을 생성할 수 있는 문서 요약 방법론을 제안한다. 구체적으로 제안 방법론은 한국어 사전학습 언어 모델인 KoBERT의 임베딩 행렬을 트랜스포머 모델에 적용하는 방식으로 문서 요약을 수행하며, 제안 방법론의 우수성은 Dacon 한국어 문서 생성 요약 데이터셋에 대한 실험을 통해 ROUGE 지표를 기준으로 평가하였다.