• The Journal of Korean Physical Therapy
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• v.17 no.4
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• pp.601-612
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• 2005

본 연구는 복직근의 기능적 전기자극이 경직형 뇌성마비 아동의 1회 호흡용적과 폐활량 등의 호흡능력과 복직근의 근육활동에 미치는 영향을 알아보기 위해서 대구 시내 OO특수학교에 재학 중인 14세 이상 16세 미만의 경직형 사지 뇌성마비 아동 6명(남자 3, 여자 3)을 대상으로 하여 복직근에 1회 20분. 주 3회씩 총 6주간 기능적 전기자극을 적용하였다. 기능적 전기자극의 적용 6주 전과, 직전에 두 번의 사전 검사와 적용 후 사후 검사를 실시하였다. MP30(Biopack, USA)을 이용하여 폐활량과 예측치 폐활량 백분율, 1회 호흡용적을 검사하였으며 Table면전극 근전도(Noraxon, USA)를 이용하여 복직근의 근육 활동량을 측정하였다. 분석결과는 다음과 같다. 1. 복직근의 기능적 전기자극 적용 6주 전과 직전의 폐활량은 유의한 차이가 없었으나, 적용 후의 폐활량은 적용 전에 비해 유의한 증가를 나타내었다(p<0.05). 2. 복직근의 기능적 전기자극 적용 6주 전과 직전의 예측치 폐활량 백분율은 유의한 차이가 없었으나, 적용 후의 예측치 폐활량 백분율은 적용 전에 비해 유의한 증가를 나타내었다(p<0.05). 3. 복직근의 기능적 전기자극 적용 6주 전과 직전의 1회 호흡용적은 유의한 차이가 없었으나, 적용 후의 1회 호흡용적은 적용 전에 비해 유의한 증가를 나타내었다(p<0.05). 4. 복직근의 기능적 전기자극 적용 6주 전과 직전의 복직근의 활동 값은 유의한 차이가 없었으나 적용 후의 복직근의 활동 값은 적용 전에 비해 유의한 증가를 나타내었다(p<0.05). 이상의 결과를 종합해 볼 때 6주간의 복직근의 기능적 전기자극이 경직형 뇌성마비 아동에 있어서 복직근의 근력을 강화시킴으로써 폐활량과 1회 호흡 용적 등의 호흡능력을 향상시킴을 확인할 수 있었다.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.6
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• pp.538-546
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• 2017

The purpose of this study was to investigate the effect of neuromuscular electrical stimulation (NMES) and transcutaneous electrical nerve stimulation (TENS) on muscular strength, pain, range of motion and fear-avoidance in anterior cruciate ligament reconstruction (ACLR) patients. The subjects of this study who received ACLR after arthroscopic injury were divided into two groups: NMES (n=14) and TENS (n=14). Each group received intervention after routine physical therapy. Each electrotherapy intervention was applied regularly for a total of 12 times, 3 times a day (30 minutes) for 4 weeks. The evaluation by intervention method included isokinetic muscle strength in flexion and extension of the knee joint, pain, range of motion of the knee joint, and fear-avoidance beliefs. The results showed significant improvement in pain, range of motion, and fear-avoidance beliefs in both groups (p<0.05). However, there was a significant improvement in isokinetic knee flexion and extension strength only in the NMES group (p<0.05). There was no significant difference between the two electrotherapy methods in muscle strength, pain, range of motion, and fear-avoidance beliefs. These study results suggest that NMES and TENS can be effective intervention methods for pain, range of motion, and fear-avoidance response in patients with ACLR, but to improve muscle strength NMES may be more effective.

• Proceedings of the KOSOMBE Conference
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• v.1995 no.11
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• pp.235-238
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• 1995

모든 살아있는 조직은 표면전위(surface electropotentials)를 가지고 있으며, 이는 조직에 손상를 가져오는 상처가 발생되었을 때 그 상처를 치료하는데 큰 역할을 담당하고 있다. 즉, 상처부위에 인위적으로 표면전위의 특성을 가진 전기적인 자극을 가함으로서 상처의 치료효과를 높일 수 있으며, 그 중에서도 상처의 발생 직후에 음(-)의 전기자극을 가할 때 높은 치료효과를 나타내는 것으로 알려져 있다. 본 연구는 상처의 치료에 전기자극을 사용할 때, 자극의 특성 변화가 치료의 효과를 높일 수 있는가에 대한 기초 연구로서 수행하였다. 즉, 쥐의 복부부위를 일정한 크기로 절개하고, 그 부위에 1mA와 10mA의 자극 펄스를 지속시간을 10msec와 100msec로 변화하면서 $1\sim3$일간 제시한 후 상처가 치료된 정도를 비교하였다. 모든 자극이 끝난 후 상처부위에 대한 조직검사를 수행하여 육아조직(granulation tissue)의 상태를 관찰하였다. 그 결과 전기자극을 전혀 가하지 않은 그룹에 비하여 전기자극을 행한 그룹들의 육아조직에 있어서 그 형성 상태가 양호하였고, 괴사현상이 나타나지 않았으며, 염증의 정도가 낮게 나타났음을 발견하였다. 또한, 자극의 횟수를 증가할수록 전기자극으로 인한 치료의 효과가 크게 나타났음을 알 수 있었다. 그러나, 각 그룹 내에서 자극의 특성을 변화시키며 수행한 검사의 결과는 큰 차이를 보이지 않았다.

• Journal of the Korean Chemical Society
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• v.48 no.2
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• pp.171-176
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• 2004

We investigated the activity and stability of alcohol oxidase from Hansenula sp. under the electric stimulation. The activity and stability of alcohol oxidase depended on electric output voltage, stimulation time, pulse duration and pulse interval. This inactivation of the enzyme under electric stimulation could be recovered by stabilizing additives such as sugars, polymers and hydrogels. The enzyme activity retained about 52% in 10% trehalose solution under electric stimulation with 40 V and 10 min. The stabilizing of enzymes against electric stimulation showed a great potential use of enzymes in biotechnology and medical engineering fields.

• Proceedings of the KAIS Fall Conference
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• 2009.12a
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• pp.491-494
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• 2009

본 논문에서는 비우세 팔굽관절 굽힘근육에 원심성운동을 실시하여, 지연성근육통을 유발시킨 후, 자연치유과 경피신경전기자극치료, 그리고 냉치료의 효과를 조사하는데 그 목적이 있다. 자연치유군과 경피신경 전기자극치료군, 그리고 냉치료군의 평가를 위해 팔꿉관절의 운동시에 시상통증척도(VAS), 최대 염력, 실 효치 값을 측정하여 평가하였다. 대상자는 신체적 결함이 없는 30명의 성인을 대상으로 하였고, 대상자들은 지연성근육통 유발 후, 3개의 군인 자연치유군, 경피신경전기자극치료군, 냉치료군으로 나누었고, $60^{\circ}$/초의 등속성 각속도에서 최대 근력으로 운동시에 최대 연력과 실효치 값, 그리고 시상통증척도를 측정하여 평가하였다. 1. 시상통증척도는 경피신경전기자극치료군의 치료3일차에서 다른 군과 다른 기간에 비해 가장 낮은 수치를 나타내었고, 통계적으로 유의하였다(p<.05). 2. 최대 염력은 경피신경전기자극치료군의 치료3일차에서 다른 군과 다른 기간에 비해 가장 높은 수치를 나타내었고, 통계적으로 유의하였다(p<.05).3. 실효치 값은 경피신경전기자극치료군의 치료3일차에서 다른 군과 다른 기간에 비해 가장 높은 수치를 나타내었고, 통계적으로 유의하였다(p<.05). 이상의 연구 결과로 보아 경피신경전기자극치료는 지연성근육통에 대하여 자연 치유나 냉치료에 비해 더욱 효과적인 치료 방법임을 알 수 있다. 그러므로, 지연성근육통을 가진 환자의 치료 시에 경피신경전기자극치료의 적용은 권장되어야 한다.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.28 no.1
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• pp.23-30
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• 1995

This study was undertaken to clarify the effects of electrical stimulation on physicochemical and rheological properties of the plaice (Paralichthys olivaceus) muscle at early period after death. The plaices were electrically stimulated in seawater bath (110V/60Hz) for 15sec., 35sec., and 60sec. and killed instantly with spiking at the head. Killed samples were stored at $5^{\circ}C$, and the changes in rigor index, ATP breakdown, lactate accumulation, and breaking strength of muscle through storage were investigated. Electrical stimulation effectively accelerated rigor-mortis, lactate accumulation , and ATP breakdown. As the time of electrical stimulation was lengthened, the onset of rigor-mortis of all samples were accelerated Just after killing, and the amount of lactate was rapidly increased, But, significant differences were not observed in variance of rigor-mortis and lactate concentration. Electrically stimulated plaices showed decreasing in ATP to $4.58{\mu}mole/g$ for 15sec., $4.13{\mu}mole/g$ for 35sec., and $2.39{\mu}mole/g$ for 60sec. samples as compared with $5.5{\mu}mole/g$ of unstimulated samples. As the time of electrical stimulation was lengthened, ATP in samples were decomposed more rapidly. The rate constant of ATP breakdown were $0.244hr^{-1}$ for 15sec., $0.358hr^{-1}$ for 35sec., and $0.479hr^{-1}$ for 60sec.. The level of breaking strength in muscle of the plaice was $1050.30\pm50.23g$ immediately after killing. Values of breaking strength in samples electrically stimulated for 35sec. increased rapidly just after killing among all samples. However, the breaking strength was not increased through the whole storage time in samples stimulated for 60sec.. The value and time roaching to the maximum breaking strength for each samples stimulated electrically for 15, 35 and 60 second were $1264.43\pm35.76g$ and 2hr, $1357.68\pm22.50g$ and Ohr, and $1012.18\pm57.36g$ and Ohr. Breaking strength in all samples electrically stimulated decreased significantly (P<0.05) after reaching the maximum values.

• Proceedings of the KAIS Fall Conference
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• 2012.05b
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• pp.808-811
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• 2012

매년 높은 비율의 전기안전사고가 발생하지만 예방교육은 단순한 영상홍보나 단순 텍스트를 이용한 교육 수준에서 주입식으로 이루어지고 있다. 항공, 군사, 전력산업 등 다양한 분야에서는 가상현실을 이용한 체험형 교육 시스템이 개발되어 운영되지만 전기안전 예방교육은 감전사고와 같은 특수한 상황의 체험과 사고를 유발시킬 수 있다는 측면에서 체험형 교육시스템이 개발 및 적용이 어렵다. 따라서 본 연구에서는 전기감전 체험교육 시스템에 저주파 자극 장치를 사용할 수 있도록 저주파 간섭형 자극기를 이용한 인체 자극의 임계값 산출시험을 실시하고 대표적으로 성별, 연령별(아동 및 성인 구분)로 구분하여 적절한 자극값을 산출하였다. 본 연구의 결과는 향후 전기안전사고 예방을 위한 체험형 예방 교육 시스템에 활용이 가능할 것이다.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.11 no.12
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• pp.2335-2342
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• 2007

Laser stimulation has been widely studied and used in clinic. However, electrical response by laser stimulation on meridians has not been investigated. In this study, we compared electric potential of laser and acupuncture stimulation on meridians. We measured electric potential variation at acupoints(Samgan(LI3) and Hapgok(LI4)) on Large Intestine Meridian. In laser stimulation results, average peak electric potential is very low($7.53{\pm}3.44{\mu}V$) for before and after stimulation. However, acupuncture stimulation was performed in ground connection condition and resulted in huge variation of average peak electric potential($2.65{\pm}1.53mV$). That is, the intensity and pattern of electric potential were dependent on the ground connection condition and individual. Also, the electric potential pattern was very similar to the pattern of electric charge and discharge of capacitor. The acupuncture stimulation using a insulating needle resulted in lower average peak electric potential variation($0.25{\pm}0.16mV$) than that of acupuncture stimulation. It might present little electrical response of acupuncture stimulation using insulating needles. In point of electrical response, the laser stimulation was determined to be no acupuncture effect at meridian. Acupuncture stimulation seems to be most effective method to induce electrical response at meridians. The procedure and effect of acupuncture might be considered as energy consensus phenomenon by transportation of bio-ion charge between a practitioner and patient.

• The Journal of the Korea Contents Association
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• v.9 no.12
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• pp.691-698
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• 2009

The purpose of this study was to examine the effect of neuromuscular electrical stimulation(LFES) during hindlimb suspension on weight and function of rat hindlimb muscles. Sprague-Dawley rats(body weight 300-350g) were randomly assigned to five groups: a HLS(n=5) that were hindlimb suspended for 14 days, a WB(n=5) that kept as control, a ES14 that were hind limb suspended for 14days with pre-application of LFES for 14 days, ES11 that were hindlimb suspended for 14 days with pre-application of LFES for 11 days, a LFES 7 that were hindlimb suspended for 14 days with pre-application of LFES for 7 days. Gastrocnemius muscle weight, stride length were significantly decreased and toe out angle were significantly increased in HLS and ES7 groups, whereas muscle weight, stride length, toe out angle were maintained in ES14, ES11. this indicated that LFES for 14 days, LFES for 11 days could prevent muscle atrophy and retain function.

• Progress in Medical Physics
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• v.19 no.1
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• pp.73-79
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• 2008

Retinal prosthesis is regarded as the most feasible method for the blind caused by retinal diseases such as retinitis pigmentosa (RP) or age related macular degeneration (AMD). Recently Korean consortium launched for developing retinal prosthesis. One of the prerequisites for the success of retinal prosthesis is the optimization of the electrical stimuli applied through the prosthesis. Since electrical characteristics of degenerate retina are expected to differ from those of normal retina, we performed voltage stimulation experiment both in normal and degenerate retina to provide a guideline for the optimization of electrical stimulation for the upcoming prosthesis. After isolation of retina, retinal patch was attached with the ganglion cell side facing the surface of microelectrode arrays (MEA). $8{\times}8$ grid layout MEA (electrode diameter: $30{\mu}m$, electrode spacing: $200{\mu}m$, and impedance: $50k{\Omega}$ at 1 kHz) was used to record in-vitro retinal ganglion cell activity. Mono-polar electrical stimulation was applied through one of the 60 MEA channel, and the remaining channels were used for recording. The electrical stimulus was a constant voltage, charge-balanced biphasic, anodic-first square wave pulse without interphase delay, and 50 trains of pulse was applied with a period of 2 sec. Different electrical stimuli were applied. First, pulse amplitude was varied (voltage: $0.5{\sim}3.0V$). Second, pulse duration was varied $(100{\sim}1,200{\mu}s)$. Evoked responses were analyzed by PSTH from averaged data with 50 trials. Charge density was calculated with Ohm's and Coulomb's law. In normal retina, by varying the pulse amplitude from 0.5 to 3V with fixed duration of $500{\mu}s$, the threshold level for reliable ganglion cell response was found at 1.5V. The calculated threshold of charge density was $2.123mC/cm^2$. By varying the pulse duration from 100 to $1,200{\mu}s$ with fixed amplitude of 2V, the threshold level was found at $300{\mu}s$. The calculated threhold of charge density was $1.698mC/cm^2$. Even after the block of ON-pathway with L-(1)-2-amino-4-phosphonobutyric acid (APB), electrical stimulus evoked ganglion cell activities. In this APB-induced degenerate retina, by varying the pulse duration from 100 to $1200{\mu}s$ with fixed voltage of 2 V, the threshold level was found at $300{\mu}s$, which is the same with normal retina. More experiment with APB-induced degenerate retina is needed to make a clear comparison of threshold of charge density between normal and degenerate retina.