• Journal of the Korean Society of Visualization
• /
• v.1 no.2
• /
• pp.47-51
• /
• 2003

Microfluidic chips such as lab-on-a-chip (LOC) include micro-channels for sample delivery, mixing, reaction, and separation. Pressure driven flow or electro-osmotic flow (EOF) has been usually employed to deliver bio-samples. Having some advantages of easy control, the flow characteristics of EOF in microchannels should be fully understood to effectively control the electro-osmotic pump for bio-sam-pie delivery. In this study, a micro PIV system with an epifluorescence inverted microscope and a cooled CCD was used to measure velocity fields of EOF in a glass microchannel and a PDMS microchannel. The EOF velocity fields were changed with respect to electric charge of seeding particles and microchannel materials used. The EOF has nearly uniform velocity distribution inside the microchannel when pressure gradient effect is negligible. The mean streamwise velocity is nearly proportional to the applied electric field. Glass microchannels give better repeatability in PIV results, compared with PDMS microchannels which are easy to fabricate and more suitable for PIV experiments.

• 한국전산유체공학회:학술대회논문집
• /
• 2005.10a
• /
• pp.27-30
• /
• 2005

In a microfluidic chips pressure driven flow or electro-osmotic flow has been usually employed to deliver bio-samples. Flow in the chips is usually slow and the mixing performance is poor. A micro-mixer with a rapid mixing is important for practical applications. In this study a newly designed and electro-osmotic driven micro-mixer is proposed. This design is comprised of a channel and a series of metal electrodes periodically attached on the side surface. In this configuration electro-osmotic flows and the stirring effects are simulated three-dimensionally using a commercial code, CFD-ACE. Focus is given the effect on the electro-osmotic flow characteristics under the local variation of the electric field.

• Journal of the Korean Society of Visualization
• /
• v.3 no.2
• /
• pp.45-50
• /
• 2005

Electro-osmotic flow (EOF) instability in a microchannel has been experimentally investigated using a micro-PIV system. The micro-PIV system consisting of a two-head Nd:Yag laser and cooled CCD camera was used to measure instantaneous velocity fields and vorticity contours of the EOF instability in a T-shape glass microchannel. The electrokinetic flow instability occurs in the presence of electric conductivity gradients. Charge accumulation at the interface of conductivity gradients leads to electric body forces, driving the coupled flow and electric field into an unstable dynamics. The threshold electric field above which the flow becomes unstable and rapid mixing occurs is about 1000V/cm. As the electric field increases, the flow pattern becomes unstable and vortical motion is enhanced. This kind of instability is a key factor limiting the robust performance of complex electrokinetic bio-analytical devices, but can also be used for rapid mixing and effective flow control fer micro-scale bio-chips.

• Transactions of the Korean Society of Mechanical Engineers B
• /
• v.39 no.6
• /
• pp.471-475
• /
• 2015

Because of increasing demand, a small portable drug injector that uses osmotic pressure for its operation force is developed, and its performance is evaluated. The osmotic drug injector can be small and lightweight because it does not require heavy batteries and an actuator, unlike previous electromechanical drug injectors. Moreover, its injection pressure can be sustained longer than that of previous elastic drug injectors. The new device is composed of a drug sac, osmotic pressure chamber, semipermeable membrane, and solvent chamber. To evaluate its performance, an in-vitro experiment was designed to measure the outflow and the injection pressure with respect to time. The experimental results show that the new drug infuser can continuously deliver 20 ml drug over a period of 20 h. The maximum injecting pressure was over 400 mmHg. Which prevents backflow caused by changes in the outlet pressure resulting from changes to the position of the device and the patient's posture.

• 한국가시화정보학회:학술대회논문집
• /
• 2005.12a
• /
• pp.107-110
• /
• 2005

In this study a newly designed and electro-osmotic micro-mixer is proposed. This design is comprised of a channel and metal electrodes attached in the local side wall surface, To investigate the flow patterns a numerical method is employed. To obtain the flow patterns numerical computation are performed by using a commercial code, CFD-ACE. The fluid-flow solutions are then cast into studying the characteristics of stirring with aid the Mixing index. Focus is given the effect on the electro osmotic flow characteristics under the curvature variation in the microchannel with the local of the electric field

• 한국전산유체공학회:학술대회논문집
• /
• 2004.10a
• /
• pp.161-164
• /
• 2004

A finite volume numerical model is developed for simulating non-equilibrium electroosmotic flow in micro- and nanochannels. The Guoy-Chapman model is adopted to compute the flow and electric potential. The Nernst-Planck equation is employed to trace unsteady transports of ionic species, i.e., time-dependent net charge density. A new set of boundary conditions based on surface charge density are designed rather than using the conventionally-employed zeta potential. A few issues for an efficient computation of electroosmotic flows are discussed. Representative computational examples are given to illustrate the robustness of the numerical model.

• Applied Chemistry for Engineering
• /
• v.34 no.1
• /
• pp.64-68
• /
• 2023

The salt concentration process in electrodialysis, which uses electrical energy to enhance ion concentrations in an aqueous electrolyte solution, has been studied on the transfer phenomenon of ions and water molecules over the ion exchange membrane. In this paper, we investigated various parameters for limiting concentration of electrolyte solution and the electroosmosis phenomenon in an electrodialysis system by varying salt concentration of electrolyte solution. The electroosmotic water transport was analyzed by measuring the ions and water fluxes in electrolyte solutions having two different NaCl concentrations (NaCl 2M/4M), and concentration change was observed for various volume ratios of the diluted reservoir to the concentration one As a result, it was found that the higher concentration of the aqueous electrolyte solution, the lower electroosmosis, and the higher volume ratio led to a higher concentration in the dilute reservoir, so the limiting concentration was enhanced and the specific energy consumption decreased.

• Transactions of the Korean Society of Mechanical Engineers B
• /
• v.35 no.4
• /
• pp.379-383
• /
• 2011

Electro-osmotic pumps were fabricated by using two types of porous glass frits. The performance of these pumps was characterized in terms of maximum flow rate, current, and pressure using deionized water and 1 mM sodium tertraborate decahydrate buffer. Maximum flow rate and current when ROBU porous glass frits were used were higher than those when DURAN porous glass frits were used because of the high porosity of the ROBU glass frits. However, the maximum pressure when ROBU glass frits were used was similar to that when DURAN glass frits were used. The therrmodynamic efficiency of a pump with ROBU porous glass frits is approximately twice that of a pump with DURAN porous glass frits. Further, the maximum flow rate at maximum current in the case of ROBU porous glass frits is high. However, it is lower than the maximum pressure at maximum current in the case of DURAN porous glass frits. Further, in this study, we also verified the effectiveness of ROBU glass frits when high flow rate is required and of DURAN glass frits when a high pressure is required.

• Journal of the Korean Society of Visualization
• /
• v.9 no.4
• /
• pp.22-27
• /
• 2011

In this study, we present methods of coupling a commercial code, ANSYS CFX, and the user Fortran codes for solving an unsteady electro-osmotic flow around a pair of electrodes, receiving DC, attached to the top and the bottom walls of a two-dimensional cavity. We developed a module of Fortran programs for solving the ion-transport equations as well as the Poisson equations for the potential to be used in coupling with the CFX. We present how the developed codes are applied to solving the transient DC electro-osmotic flow problem within a simple cavity. We also address various problems encountered during the development process and explain why such problems are raised.

• Journal of computational fluids engineering
• /
• v.12 no.1
• /
• pp.16-21
• /
• 2007

This paper presents numerical results of fluid flows and mixing in a microfluidic device with AC electroosmotic flows (AC-EOF) around coplanar electrodes attached on the top and bottom walls. To obtain the flow and mixing characteristics, numerical computations are performed by using a commercial code, CFX10. Experiment was performed to confirm the generation of the drift velocity around the electrodes. It was found that near the coplanar electrodes 3-D complex flows are generated. The AC-electroosmotic flow on the electrodes plays an important role in mixing the liquid.