• Title/Summary/Keyword: 적분생물학적유효선량

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Optimization of Total Arc Degree for Stereotactic Radiotherapy by Using Integral Biologically Effective Dose and Irradiated Volume (정위방사선치료 시 적분 생물학적 유효선량 및 방사선조사용적을 이용한 Total Arc Degree의 최적화)

  • Lim Do Hoon;Lee Myung Za;Chun Ha Chung;Kim Dae Yong
    • Radiation Oncology Journal
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    • v.19 no.2
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    • pp.199-204
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    • 2001
  • Purpoe : To find the optimal values of total arc degree to protect the normal brain tissue from high dose radiation in stereotactic radiotherapy planning. Methods and Materials : With Xknife-3 planning system & 4 MV linear accelerator, the authors planned under various values of parameters. One isocenter, 12, 20, 30, 40, 50, and 60 mm of collimator diameters, $100^{\circ},\;200^{\circ},\;300^{\circ},\;400^{\circ}C,\;500^{\circ},\;600^{\circ}$ or total arc degrees, and $30^{\circ}\;or\;45^{\circ}$ or arc intervals were used. After the completion of planning, the plans were compared each other using $V_{50}$ (the volume of normal brain that is delivered high dose radiation) and integral biologically effective dose. Results : At $30^{\circ}$ of arc interval, the values of $V_{50}$ had the decreased pattern with the increase of total arc degree in any collimator diameter. At 45 arc interval, up to $400^{\circ}$ of total arc degree, the values of $ V_{50}$ decreased with the increase of total arc degree, but at $500^{\circ}\;and\;600^{\circ}$ of total arc degrees, the values increased. At $30^{\circ}$ of arc interval, integral biologically effective dose showed the decreased pattern with the increase of total arc degree in any collimator diameter. At $45^{\circ}$ arc interval with less than 40 mm collimator diameter, the integral biologically effective dose decreased with the increase of total arc degree, but with n and n mm or collimator diameters, up to $400^{\circ}$ or total arc degree, integral biologically effective dose decreased with the increase of total arc degree, but at $500^{\circ}\;and\;600^{\circ}$ of total arc degrees, the values increased. Conclusion : In the stereotactic radiotherapy planning for brain lesions, planning with $400^{\circ}$ of total arc degree is optimal. Especially, when the larger collimator more than 50 mm diameter should be used, the uses of $500^{\circ}\;and\;600^{\circ}$ of total arc degrees make the increase of$V_{50}$ and integral biologically effective dose. Therefore stereotactic radiotherapy planning using $400^{\circ}$ of total arc degree can increase the therapeutic ratio and produce the effective outcome in the management of personal and mechanical sources in radiotherapy department.

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