• Journal of Life Science
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• v.23 no.1
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• pp.116-124
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• 2013

The aim was to examine resistance exercise-related genes after 8 weeks of resistance training. Thirty-two male Sprague-Dawley rats were divided into four groups: 4 weeks sedentary (4 wks CON, n=8), 8 weeks sedentary (8 wks CON, n=8), 4 weeks exercise training (4 wks REG, n=8), and 8 weeks exercise training (8 wks REG, n=8). The rats were trained to climb a 1-m vertical incline (85-degree), with weights secured to their tails. They climbed 10 times, 3 days per week, for 8 consecutive weeks. Skeletal muscle was taken from the flexor halucis longus after the exercise training. After separating the total RNA, large-scale gene expression was investigated by beadarray (Illumina RatRef-12 Expression BeadChip) analysis, and qPCR was used to inspect the beadarray data and to analyze the RNA quantitatively. The detection p-value for the genes was p<0.01, the M-value {M=$log_2$(condition)-$log_2$(reference)} was >1.0, and the DiffScore was >20. In total, the expression of 30 genes significantly increased 4 weeks after the exercise training, and the expression of six genes decreased. At 8 weeks, the expression of five genes significantly increased and that of 12 decreased. Several genes are potentially involved in resistance exercise and muscle hypertrophy, including 1) regulation of cell growth (IGFBP1, PLA2G2A, OKL38); 2) myogenesis (CSRP3); 3) tissue regeneration and muscle development (MUSTN1, MYBPH); 4) hypertrophy (CYR61, ATF3, NR4A3); and 5) glucose metabolism (G6PC, PCK1). These results may help to explain previously reported physiological changes of the skeletal muscle and suggest new avenues for further investigation.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.6
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• pp.181-191
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• 2016

This study examined the effects of exercise intensity and type on insulin resistance, cardiovascular disease risk factors, and exercise time. Obese thirty-two subjects (>body fat 30%) were randomly assigned one of four experimental groups: VO2 max 50% aerobic exercise group (MAE, n=8), VO2 max 80% aerobic exercise group (VAE, n=8), VO2 max 50% + resistance exercise group (MARE, n=8), and VO2 max 80% + resistance exercise group (VARE, n=8). Body fat significantly decreased in all groups and insulin resistance decreased significantly in MARE and VARE (p<.05 & p<.01) after exercise. CRP and IL-6 were slightly reduced after exercise, although these did not reach statistical significance, whereas the IL-6 level of the VAE group decreased significantly (p<.05). TNF-${\alpha}$ significantly decreased in the MAE group (p<.05) but significantly increased in the VARE group after exercise (p<.05). For exercise time, higher intensity exercise groups were significantly less than the lower intensity exercise groups (p<.001). These results suggest that body fat is affected by all kinds of exercise intensity and type while CRP is not. Insulin resistance and TNF-${\alpha}$ were affected by exercise type, whereas IL-6, TNF-${\alpha}$, and exercise time were affected by exercise intensity.

• Journal of the Korean Applied Science and Technology
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• v.37 no.6
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• pp.1669-1677
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• 2020

The purpose of this study was to evaluate the effects of a 14-week proprioceptive resistance exercise on muscle endurance strength, dynamic balance and gait ability of elderly women in a social welfare facility. Thirty community dwelling elderly subjects (mean age 70.84±3.33) divided into experimental (n=15) and control (n=15) groups. The participants performed the muscle endurance strength(30sec hair stand), dynamic balance (3m up and go) and low extremity performance (10m walking, 400m walking) pre and after the training program. The exercise groups were submitted to 14 weeks proprioceptive training with a Swiss ball three times a week. As a results were as follow. Significantly improvements were observed in low extremity strength and dynamic balance. And there have significantly improvements in 10m walking, 400m walking. Conclusionly, the improvement of dynamic balance and gait ability by proprioceptive resistance training will reduce the possibility in female elderly people.

• Journal of the Korean Applied Science and Technology
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• v.36 no.4
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• pp.1108-1118
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• 2019

The purpose of this study was to examine the effects of aerobic and resistance exercise of different intensity on anti-diabetic and lipid profile improvement in type 2 diabetic mice. C57BL/6 mice were divided into six groups (n=8, in each group): normal group (Normal), type 2 diabetes (DM), type 2 diabetes+VO₂max 50% aerobic exercise group (DM50A), type 2 diabetes+VO₂max 75% aerobic exercise group (DM75A), type 2 diabetes+1RM 50% resistance exercise group (DM50R), and type 2 diabetes+1RM 75% resistance group (DM75R). DM50A and DM75A were subjected to treadmill exercise 40 min/day, 5 days/week, during 8 weeks (DM50A, at the speed of 8 m/min for 1-4 weeks and 8~10 m/min for 5-8 weeks; DM75A, 12 m/min for 1-4 weeks and 12~14 m/min for 5-8weeks). DM50R (1RM50%) and DM75R (1RM75%) were subjected to ladder-climbing exercise with weights secured to their tails, 8 set/day, 5 days/week, during 8 weeks. After 8 weeks of exercise, fasting blood glucose and HOMA-IR was significantly lower in DM group than in DM group. HbA1c showed significantly lower DM50R and DM75R groups than DM group. HDL-C showed the highest level in DM75A group and triglyceride was lowest in DM75R group. The cardiovascular risk index was lowest in the Normal and DM75A groups. Therefore, moderate intensity exercise in T2DM mice showed better improvement in blood glucose and insulin resistance control, and moderate intensity aerobic exercise was effective in reducing the cardiovascular risk index by increasing HDL-C levels.

• Korean journal of applied entomology
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• v.55 no.1
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• pp.1-9
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• 2016

Edible insects are an interesting alternative global food resource. The purpose of this study was to investigate whether ingestion of silkworm (Bombyx mori) pupae powder with and without resistance exercise training (isometric contraction training) increased muscle mass in ICR mice. To achieve this, 28 ICR mice were grouped into control (CON), resistance exercise training (EX), silkworm pupae powder ingested control (SP), and silkworm powder ingestion with resistance exercise training (SPEX) groups. The change in body weight ratio was significantly decreased in the EX and SPEX groups compared to the CON and SP groups. Total blood protein levels were the highest in SPEX mice compared to those in other groups. The albumin concentration increased only in the EX group. Blood GOT and GPT levels were not significantly affected. Changes in Akt and Gsk-$3{\beta}$ protein expression were not significant but there was a tendency for Akt to increase and for Gsk-$3{\beta}$ to increase following the ingestion of the powder. The size of the gastrocnemius muscle increased significantly in response to resistance exercise training only. Furthermore, the ingestion of silkworm pupae powder tended to increase muscle mass without significance. These results suggested that the ingestion of silkworm pupae powder with resistance exercise training might enhance muscle mass without hepatotoxicity. However, future study may be needed to obtained detailed results and practical suggestions.

• Journal of Digital Convergence
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• v.16 no.2
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• pp.375-383
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• 2018

The purpose of this study was to investigate the effect of exercise training on health-related physical fitness and osteoporosis after 12 weeks of combined training for adults with intellectual disabilities diagnosed with obesity and osteoporosis. The subjects conducted a combined training program consisting of aerobic exercise and strength training twice a week for 12 weeks. Body composition and bone mineral density were measured before exercise, 6, 12 weeks, and health-related physical fitness was measured before and after exercise. Body weight and body fat decreased after exercise and bone density increased after exercise compared to before exercise. Muscle strength, muscle endurance and flexibility were improved after exercise compared to before exercise. It was confirmed that the 12 week compound training increased the leg strength and improved the functions such as walking and running, and increased the health-related fitness and increased bone mineral density.

• Proceedings of the KAIS Fall Conference
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• 2009.05a
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• pp.347-350
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• 2009

본 연구는 복합운동 유형 순서 변화에 따른 생리적, 생화학적 변화를 비교 하고자 40대 비만여성을 대상으로 12주간 복합운동을 실시하였다. 복합운동 유형은 유산소성 운동과 저항성 운동그룹 그리고 저항성 운동과 유산소성 운동그룹으로 구성하였다. 체지방량의 경우 A그룹의 평균변화량이 B그룹 평균변화량보다 더 많이 감소하였고 통계적으로 유의한 차이를 보였다(p<0.01). 혈당의 경우는 A그룹보다는 B그룹이 더 많이 감소하였으며 통계적으로 유의한 차이를 보였다(p<0.01). 따라서, 비만 중년 여성의 체중감량을 위한 신체구성 변화 유도를 위해서는 복합운동의 순서 변화에 따른 운동유형이 선택적으로 사용되어질 수 있다.

• 한국노년학
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• v.29 no.3
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• pp.987-1000
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• 2009

The purpose of the study was to examine the effect of resistance training on joint flexibility and muscle strength of upper extremities of institutionalized elderly with impaired cognition. The study design was pretest-posttest control group study and inclusion criteria were elderly aged 65-year older, MMSE score 23 or less, ones who had no serious physical and/or mental problem except impaired cognition, and were capable to carry out resistance training. After consents were obtained participants were randomly assigned. Pre-post evaluation was performed by staff nurses trained beforehand. Among those 4-week study period, experiment was carried out during 5 consecutive days a week for 3 weeks. ROM and extension range of shoulder joints and muscle strength of shoulders and hands for both sides were measured. Flexion, extension, abduction range of right shoulder joint was significantly improved. Flexion and extension muscle strength of left side shoulder and abduction muscle strength of both sides of shoulder were significantly improved. With the study result, it could be concluded that resistance training has therapeutic effects on joint flexibility and muscle strength. More studies adopted longer experimental period to evaluate timing of effect and extinction to refine the protocol are called for.

• Proceedings of the Korea Contents Association Conference
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• 2018.05a
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• pp.291-292
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• 2018

이 연구의 목적은 대상자의 팔과 다리를 연구자가 잡아당기고, 저항을 준 상태로 대상자가 대상자의 몸통으로 가져가는 수동적 가동범위의 운동인 '저항굴곡MS운동'이 코어를 강화시켜주는 운동임을 증명한다. 또한 본 연구의 목적은 누군가의 작은 도움이 근육강화와 유연성은 물론 관절의 기능회복에 도움을 주며 류마티스 관절염 통증완화에 미치는 영향을 알아보고자하는데 있다.

• Journal of the Korea Convergence Society
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• v.12 no.12
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• pp.411-418
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• 2021

The purpose of this study was to find out the effects of isomatric and isotonic exercise on the muscle function and cytokine which will prevent recurrence of breast cancer patients. A subjects were thirteen breast cancer patients and they were randomly assigned either isometric exercise group(n=10), isotonic exercises group(n=10) or a daily base care control group(n=10). Resistance exercise group did a exercise program with 60~70%RM for 60min, 3days per week during 8week. There were significantly difference between groups which were showing a increasing flexion, abduction, external rotation, IL-6 and IL-10 in isotonic exercise.