• Journal of Dental Rehabilitation and Applied Science
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• v.27 no.2
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• pp.175-184
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• 2011

With a development of implant restoration technique, there are increasing use of computer-guided system for edentulous patients. It was carried out simulated operation based on CT information about patient's bone quantity, quality and anatomical landmark. However, there are some difference between the programmed implant and post-operative implant about it's position. If the deviation was severe, it could happen a failure of 'passive fit' and not suited for path of implant restoration. The aim of this presentation is to evaluate about a degree of deviations between programmed implant and post-operative implant. Five patients treated by 'NobelGuide' system (Nobel Biocare AB, G$\ddot{o}$teborg, Sweden) in Department of Prosthodontics, Inha University were included in this study. The patients were performed CT radiograph taking and intra-oral impression taking at pre-operation. Based on CT images and study model, surgical stent was produced by NobelBiocareTM. To fabricated a pre-operative study model, after connected lab analog to surgical template, accomplished a pre-operative model using type 4 dental stone. At final impression, a post-operative study model was fabricated in the conventional procedures. Each study model was performed CT radiograph taking. Based on CT images, each implant was simulated in three dimensional position using $Procera^{(R)}$ software (Procera Software Clinical Design Premium, version 1.5; Nobel Biocare AB). In 3D simulated model, length and angulation between each implant of both pre- and post-operative implants were measured and recorded about linear and angular deviation between pre-and post-operative implants. A total of 24 implants were included in this study and 58 inter-implant sites between each implant were measured about linear and angular deviations. In the linear deviation a mean deviation of 0.41 mm (range 0~1.7 mm) was reported. In the angular deviation, a mean deviation was $1.99^{\circ}$ (range $0^{\circ}{\sim}6.7^{\circ}$). It appears that the both linear and angular mean deviation value were well acceptable to application of computer-guided implant system.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.33 no.1
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• pp.1-12
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• 2021

To investigate the effect of freshwater discharge on the seawater circulation in the semi-closed harbor, a 3-D hydrodynamic model was applied to the International Ferry Terminal (IFT). The model run is conducted for 45 days (from May 15 to June 30, 2020), and the reproducibility of the model for time-spatial variability of current velocity and salinity was verified by comparison with model results and observation data. There are two sources of freshwater towards inside of the IFT: Han River and water reservoir located in the eastern part of IFT. In residual current velocity results, the two-layer circulation (the seaward flow near surface and the landward flow near bottom)derived from the horizontal salinity gradient in only considering the discharge from a Han River is more developed than that considering both the Han River and water reservoir. This suggests that the impact of freshwater from the reservoir is greater in the IFT areas than that from a Han River. Additionally, the two-layer circulation is stronger in the IFT located in southern part than Incheon South Port located in northern part. This process is formed by the interaction between tidal current propagating into the port and freshwater discharge from a water reservoir, and flow with a low salinity (near 0 psu) is delivered into the IFT. This low salinity distribution reinforces the horizontal stratification in front of the IFT, and maintains a two-layer circulation. Therefore, local sources of freshwater input are considered to estimate for mass transport process associated with the seawater circulation within the harbor and It is necessary to perform a numerical model according to the real-time freshwater flow rate discharged.

• Reproductive and Developmental Biology
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• v.38 no.3
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• pp.123-127
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• 2014

This study was conducted for SNPs in the 5'-regions of estrogen receptor-${\alpha}$ (ESR-${\alpha}$), and association with calving interval (CI), service per conception (SPC) and 305 days milk yield in Hanwoo and Holstein dairy cattle. The genetic improvement was incurred low reproduction performance. The objective of this study was to investigate connections between single nucleotide polymorphisms (SNP) of Estrogen receptor-${\alpha}$ (ESR-${\alpha}$) with reproduction performance (calving interval, service per conception, and 305 d milk yield) in Hanwoo and Holstein dairy cattle. Hanwoo and Holstein blood samples were collected from 183 and 124 dam of breeding farms and DNA was extracted. Primer design was based on NCBI GenBank (Accession No. AY340579). The PCR-RFLP method with Bgl I was used to genotype the cattle. The result showed two variants of the ESR-${\alpha}$ gene. The Bgl I cut the 492 bp amplification product into 322 bp and 170 bp fragments for allele G, while allele A remained uncut, resulting in two restriction fragments for homozygote G/G and three fragments for heterozygote A/G. We found two of different genotypes in these breeds, A/G and G/G. In Hanwoo, the A/G genotype frequency was 0.13, and G/G was 0.87. The CI of A/G was $382.18{\pm}10.03$ days, and G/G was $381.69{\pm}5.22$ days. The SPC of A/G was $1.62{\pm}0.16$, and G/G was $1.32{\pm}0.04$. While CI showed no significance difference, SPC exhibited significant difference (p<0.05). In Holstein cattle, the frequency of genotype A/G was 0.02 and G/G was 0.98. The 305 days milk yield of A/G was $7,253.00{\pm}936.00kg$ and of G/G was $8,747.51{\pm}204.88kg$, showing no significant difference.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.12
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• pp.6447-6454
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• 2013

Seawater intake systems have significant problems due to seawater pollution, suspended solids, unstable intake and maintenance etc. An underground type seawater intake system was newly developed to overcome the existing weaknesses and was facilitated in Gyukpo port. In this study, to check the performance of the new system, the samples for water quality and the 3-D numerical modeling test were conducted. The five times test included the COD, total nitrogen, total phosphorus, pH, and suspended solid for the intake system. The analyses show that the COD, total nitrogen, total phosphorus, PH showedminor changes before and after. On the other hand, the change in suspended solids was significant and water was purified below 5 mg/l, first level fisheries water, after. The numerical model adopted the RNG $k-{\epsilon}$ algorithm and the CFX model based on the finite volume method. The porosity algorithm was used to reproduce filtered-sand, outer diameter, and thickness. The numerical results showed that the double pipe is advantageous in that it provides a uniform pressure between the inner and outer pipe for the flow to be stable. In addition, the use of multiple intake pipes did not interfere with the discharge reduction of 0.98 at the both intake pipes compared with the central intake pipe.

• Journal of the Korean Geotechnical Society
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• v.33 no.3
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• pp.37-47
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• 2017

The geotechnical characteristics of frozen ground is one of the key design issues for the construction of infrastructure in cold region. In this study, the dynamic properties (shear modulus and damping ratio) of frozen and unfrozen soils sampled from Terra Nova Bay located in eastern Antarctica, where Jang Bogo station was built, were investigated using Stokoe-type resonant column test (RC). In order to freeze the reconstituted soil specimen, the RC testing equipment was modified by adding a cooling system. A series of resonant column tests were performed in frozen and unfrozen soils with various soil densities and temperatures. The shear modulus (G) and damping ratio (D) of soil frozen at $-7^{\circ}C$ were compared with those of unfrozen soil. In addition, the effect of temperature rise on the maximum shear modulus ($G_{max}$) and damping ratio was experimentally investigated. This study has significance in that the difference of dynamic soil properties between frozen and unfrozen soils and the effect of temperature rise on frozen soil were identified.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.24 no.2
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• pp.97-108
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• 2012

A Lagrangian particle tracking model coupled with the ECOM3D were used to study on the behavior of fresh water released from the Namgang Dam in terms of residence time in Kangjin Bay, South Sea, Korea. Model was calibrated until skill cores for elevation, velocity, temperature and salinity are satisfied over 85%. In the numerical simulation, particles were released in 1 hour time interval from the northern boundary. The different patterns of particle trajectory are identified under the varying dynamics from tidal to density-driven current. The average residence time of total particles are approximately 65.9 hours in the entire Kangjin Bay. The average residence time were increased from 55~65 to 70~80 hours during maximum discharge period. Discharge rate of fresh water and average residence time in the Kangjin Bay is high correlated with correlation coefficient over 0.81.

• Journal of the Korean Society for Marine Environment & Energy
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• v.14 no.2
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• pp.107-113
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• 2011

To evaluate the performance of the hydrodynamic model, we introduced 10 skill assessments that are assorted by two groups: quantitative skill assessments (Absolute Average Error or AAE, Root Mean Squared Error or RMSE, Relative Absolute Average Error or RAAE, Percentage Model Error or PME) and qualitative skill assessments (Correlation Coefficient or CC, Reliability Index or RI, Index of Agreement or IA, Modeling Efficiency or MEF, Cost Function or CF, Coefficient of Residual Mass or CRM). These skill assessments were applied and calculated to evaluate the hydrodynamic modeling at one of Florida estuaries for water level, current, and salinity as comparing measured and simulated values. We found that AAE, RMSE, RAAE, CC, IA, MEF, CF, and CRM are suitable for the error assessment of water level and current, and AAE, RMSE, RAAE, PME, CC, RI, IA, CF, and CRM are good at the salinity error assessment. Quantitative and qualitative skill assessments showed the similar trend in terms of the classification for good and bad performance of model. Furthermore, this paper suggested the criteria of the "good" model performance for water level, current, and salinity. The criteria are RAAE < 10%, CC > 0.95, IA > 0.98, MEF > 0.93, CF < 0.21 for water level, RAAE < 20%, CC > 0.7, IA > 0.8, MEF > 0.5, CF < 0.5 for current, and RAAE < 10%, PME < 10%, CC > 0.9, RI < 1.15, CF < 0.1 for salinity.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.3
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• pp.715-722
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• 2009

The aim of this study was to investigate the safety of short-term use of Korean herbal medicine (KHM; prescribed herbal medicine by doctors of traditional Korean medicine) on liver function. Three hundred eighty four outpatients who took KHM for various conditions were enrolled for multi-center, prospective observational study. Of them 237 patients completed questionnaire and were checked liver function (aspartic aminotransferase;AST, alanine aminotransferase;ALT, alkaline phosphatase;ALP, total bilirubin;t-Bil, direct bilirubin;d-Bil, gamma glutamyltranspeptidase;GGT, protein and albumin) before and after taking KHM (duration; 21.4${\pm}$10.0 days), and data were analysed statistically. Of the 213 patients showing normal liver function test (LFT) at baseline, 209 (98.1%) remained within the normal range at the second test while 3 (1.4%) revealed slight increase of LFT. Only one subject had raised LFT regarding level of liver injury without perceived symptoms. Twenty-four of 237 patients were abnormal at baseline, and 16 at the second testing. Of the patients taking KHM, only 4 changed from normal to abnormal while 12 from abnormal to normal in their LFT. There were no significant increase in LFT level between the first and second test, except in the t-Bil level, however, the change of t-Bil was small and within normal range. The current study showed that the use of KHM did not increase the frequency of abnormal LFTs, at least in the short term.

• Journal of the Korean Electrochemical Society
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• v.23 no.3
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• pp.66-72
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• 2020

In this study, the development of biosensors capable of bi-enzyme reactions by including Horseradish peroxidase and glucose oxidase was carried out for detection of glucose. The sensors were manufactured using electro deposition method to reduce production time, and screen printed electrodes (SPE) were used to produce economical sensors. To check the bienzyme effect, the sensor was compared and analyzed with single enzyme biosensor. The characteristics of the sensor were evaluated using scanning electron microscopy(SEM), cyclic voltammetry(CV), electrochemical impedance spectroscopy(EIS), chronoamperometry(CA), and flow injection analysis(FIA). Analysis results from SEM, CV and EIS confirmed that the enzymes are well fixed to the electrode surface. In addition, it was confirmed that bi-enzyme biosensors manufactured from the CA method improved signal performance by 200% compared to single enzyme biosensors. From this results, we were able to explain that HRP and GOD react catalyzed to each other. And the results of FIA showed that the intensity of each current signal was constant when the same concentration of glucose was injected four times. In addition, by analyzing the intensity of current signals for glucose concentrations, the biosensors manufactured in this study showed excellent trends in signal sensitivity, reproducibility and stability.

• Journal of the Korean Geotechnical Society
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• v.30 no.11
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• pp.51-60
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• 2014

Load and Resistance Factor Design (LRFD) is one of the limit state design methods, and has been used worldwide, especially in North America. Also, the study for LRFD has been actively conducted in Korea. However, the data for LRFD in Korea were not sufficient, so resistance factors suggested by AASTTO have been used for the design in Korea. But the resistance factors suggested by AASHTO represent the characteristics of bedrocks defined in the US, therefore, it is necessary to determine the resistance factors for designs in Korea, which can reflect the characteristics of bedrocks in Korea. Also, the calculated probabilities of failure from conventional reliability analyses which commonly use log-normal distribution are not realistic because of the lower tail that can be extended to zero. Therefore, it is necessary to calibrate the resistance factors considering the lower-bound resistance. Thus, this study calculates the resistance factors using thirteen sets of drilled shaft load test results, and then calibrates the resistance factors considering the lower-bound resistance corresponding to a target reliability index of 3.0. As a result, resistance factors from conventional reliability analyses were determined in the range of 0.13-0.32 for the shaft resistance, and 0.19-0.29 for the base resistance, respectively. Also, the lower bounds of resistance were determined based on the Hoek-Brown failure criteria (2002) and GSI downgrading. Considering the lower-bound resistances, resistance factors increased by 0~8% for the shaft, and 0~13% for the base, respectively.