• Title/Summary/Keyword: 재생의료

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특집 : 극한환경재료기술 - 극저온에서의 고분자 복합재료 기술 현황

  • Eom, Mun-Gwang;Lee, Jin-U;Lee, Won-O
    • 기계와재료
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    • v.21 no.4
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    • pp.48-55
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    • 2010
  • 극저온에서 고분자 복합재료는 열전도도가 낮아 단열 특성이 탁월하고 전기절연성이 뛰어나 에너지 산업, 전기 및 전자산업, 생물공학, 의료분야, 수송산업, 우주 항공 산업 등 응용 범위가 매우 광범위하고, 산업 규모 또한 지속적으로 성장하고 있다. 향후 신재생 에너지의 저장 및 수송용으로 열전도도가 낮은 고분자 복합재에 대한 수요가 크게 증가할 것으로 예상된다. 따라서 본 고에서는 고분자 복합재료의 극저온 응용에 관한 국내외 기술동향과 수지 및 복합재 물성, 극저온에서의 특성 평가 기술 등에 대하여 소개하였다.

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다공성 타이타늄 지지체의 생체적합성에 관한 연구

  • Kim, Seung-Eon;Hyeon, Yong-Taek;Yun, Hui-Suk;Heo, Su-Jin;Lee, Si-U;Sin, Jeong-Uk;Kim, Yeong-Gon
    • Proceedings of the Materials Research Society of Korea Conference
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    • 2009.05a
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    • pp.49.1-49.1
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    • 2009
  • 최근 손상된 생체조직의 재생 또는 대체를 위하여 다공성의 지지체(scaffold)를 이용하는 연구가 활발히 이루어져 왔다. 지지체 재료는 조직 재생을 목적으로 하는 경우에는 생분해성 고분자, 생흡수성 세라믹스 또는 이들의 복합재료가 사용되고, 조직 대체를 목적으로 하는 경우에는 금속 또는 세라믹스 재료가 단독으로 사용된다. 현재 경조직 대체를 위한 임플란트 재료로 사용되고 있는 금속재료 중 대부분이 타이타늄 또는 타이타늄 합금이다. 타이타늄은 비강도, 내식성이 우수하며, 생체 내 환경에서 부동태피막 재생 속도가 빠르고, 섬유상 결체조직 형성 두께가 얇아 생체의료용 소재로서 각광을 받고 있다. 다공성 타이타늄은 기존 타이타늄 소재의 장점에 다공체의 구조적인 특성을 부가하여 하중을 받는 골 결손부에 사용될 경우 뼈와의 탄성계수 차이에서 기인하는 응력차폐(stress shielding) 효과를 최소화할 수 있고, 다공체 내부로 골조직 성장을 유도할 수 있어 지지체와 골조직이 일체화되는 골융합 효과의 극대화를 기대할 수 있다. 본 연구에서는 기공 구조를 다양하게 제어할 수 있고, 3차원적 연결 기공구조를 만들 수 있는 적층조형(layer manufacturing) 기술을 이용하여 3차원 다공성 타이타늄 지지체를 제조하였으며, 이에 대한 세포독성, 조골세포 증식능 등 in vitro 생체적합성을 평가하고, Rat model 을 이용한 in vivo 생체적합성을 평가하였다. 또한 지지체의 골조직 재생 유도성의 증대를 위한 생체활성처리 영향도 분석 평가하였다.

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Regenerative medicine using dental tissue derived induced pluripotent stem cell-biomaterials complex (구강조직유래 유도만능줄기세포-생체재료 복합체의 재생의료 동향)

  • Jun, Soo-Kyung;Lee, Hae-Hyoung;Kim, Hae-Won;Lee, Jung-Hwan
    • The Journal of the Korean dental association
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    • v.55 no.12
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    • pp.828-840
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    • 2017
  • In recent years, many researchers and clinicians found interest in regenerative medicine using induced pluripotent stem cells (iPSCs) with biomaterials due to their pluripotency, which is able to differentiate into any type of cells without human embryo, which of use is ethically controversial. However, there are limitations to make iPSCs from adult somatic cells due to their low stemness and donor site morbidity. Recently, to overcome above drawbacks, dental tissue-derived iPSCs have been highlighted as a type of alternative sources for their high stemness, easy gathering, and their complex (ectomesenchymal) origin, which easily differentiate them to various cell types for nerve, vessel, and other dental tissue regeneration. In other part, utilizing biomaterials for regenerative medicine using cell is recently highlighted because they can modulate cell adhesion, proliferation and (de)differentiation. Therefore, this paper will convey the overview of advantages and drawbacks of dental tissue-derived iPSCs and their future application with biomaterials.

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Current Status of Collection and Recycling of Used Plastics (폐플라스틱의 수거 및 재활용 현황)

  • 나근배
    • Resources Recycling
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    • v.6 no.2
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    • pp.47-59
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    • 1997
  • Thc paper points oul ever increasing amounts of plastics used in dex, clopmg countries and the prohlelns associated with such increase. Tl~e current status of the production and usc of plaslic materials is reviewed. Also reviewed lncludc thc pahcicies and gu~dclmcs canccrning the treatment of used plastics which have already bccn mstitutcd.

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Diagnostic Medical Image Compression Method using Visually Lossless Threshold on JPEG2000 (JPEG2000에서 시각적 무손실 임계값을 이용한 진단의료영상 압축기법)

  • Bong, Jeong-Sik;Yang, Gi-Joo;Jeon, Joon-Hyeon
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.34 no.7C
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    • pp.671-680
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    • 2009
  • The diagnostic medical images(CT, MRI) in PACS require large storage and long transmission time. A simple and cheap way of overcoming these limitations is to increase the compression ratio. However, this requires a clinical validation for accurate diagnostic applications. The aim of this paper is to improve the compression efficiency of lossless JPEG2000 for diagnostic CT images by performing a visual-Iossless threshold filtering in high frequency subband. A proposed method, based on 5/3 reversible DWT, provides different subband-threshold values according to the compression ratio and gives the high subjective quality to reconstructed diagnostic CT images.

생체의료용 다공성 타이타늄 특성평가 및 표면제어 연구

  • Hyeon, Yong-Taek;Kim, Seung-Eon
    • Proceedings of the Materials Research Society of Korea Conference
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    • 2009.05a
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    • pp.47.2-47.2
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    • 2009
  • 인체의 뼈와 같은 손상된 경조직을 치료 또는 대체하기위한 정형외과용 임플란트를 설계하는데 있어 뼈의 생체역학적 특성과 유사한 성질을 갖는 다공성 지지체에 대한 연구가 최근 관심을 끌고 있다. 다공성 지지체는 조직이 원활히 재생될 수 있어야 하며, 또한 주변 조직과도 생물학적인 고착이 잘 되도록 기공들이 상호 연결된 구조를 가져야 한다. 이와 같은 다공성 지지체용 소재를 제조하기 위하여 본 연구에서는 타이타늄 분말을 사용하여 3차원 적층조형공정으로 다공성 타이타늄 지지체를 제조하였다. 제조된 다공체의 물성 및 기계적 특성을 평가하기 위하여 압축시험과 변형해석을 수행하였으며, 아울러 제조된 지지체의 생체적합성 향상을 위하여 양극산화 공정 등의 표면처리를 수행하여 그에 대한 특성을 평가하였다. 분말야금 공정으로 제조된 지지체는 골조직의 성장에 적합한 약 $300\sim400{\mu}m$의 기공 크기를 갖도록 제어하였고, 기공도는 60~75%로 제어하였다. 아울러 다공성 타이타늄의 생체적합성을 부여하기 위하여 양극산화공정으로 지지체의 표면에 Ca 및 P을 포함하는 산화층을 형성시키는 표면처리를 수행하였다. 양극산화공정에 의하여 표면에 미세기공을 포함하는 산화층을 형성시킬 수 있었으나 이와 같은 표면구조는 조골세포의 부착과 영향에는 큰 영향을 미치지 않는 것으로 확인되었다.

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Revitalizing Plan for Public Using Building through Current Status Survey in Rural Residential Area (농촌주거지역의 실태조사를 통한 공동이용건축물의 재생방안)

  • Park, Jun-Mo;Kim, Ok-Kyue
    • Journal of the Korea Institute of Building Construction
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    • v.15 no.1
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    • pp.53-64
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    • 2015
  • A demand of public using building in rural residential area changes over times. With the changes, the function and the scale of the public using building are also changed, the building is more influences on people in rural area. However, the most of facilities have been focused on the agricultural productions, and thus the facilities of health care, culture, and daylife supporting were not enough comparing to the facilities in urban area. This study surveys the facility and grasps the current status and problem of 37 rural residential area. In addition, three different revitalizing plans of public using building as a current availability and plan for use are suggested. A new community center where is expected that the public usage is increased should be managed intensively regarding an air conditioning, and waterproofing work, while an old community center and the warehouse where are expected that the public usage is decreased, but have locational advantage should be used as a rural life experience facilities and a accommodations with remodeling unless the safety matter A parking lots are considered that the availability is gradually increased and needed for public while it is difficult to get a new available site because of the ownership. Therefore, it is national decision to secure the site by removing the discarded facilities.

An Implementation of Context-Awareness Support System based on Voice Service for Medical Environments (의료 환경을 위한 음성 서비스 기반의 상황인식 지원 시스템의 구현)

  • Shim, Choon-Bo;Shin, Yang-Won;Park, Byung-Rae
    • Journal of the Korea Society of Computer and Information
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    • v.10 no.4 s.36
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    • pp.29-36
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    • 2005
  • As computing environments are more rapidly developed, an adaptive and intelligent services using post PC such as PDA. Laptop, and Tablet PC in case of rounding and examining patients are highly demanded. The objective of this study is to design and implement a context-awareness support system based on voice service for medical environments. To achieve it, we propose a context middleware which plays an important role in recognizing a client with PDA by using a Bluetooth wireless communication technology as well as in executing an appropriate execution module, like delivery for diagnosis information of patients, according to the staff's context acquired from a context server. In addition, the context server functions as a manager that efficiently stores context information such as client's current status, physical environment, and device resources into a database server. Finally, for verifying the usefulness of the proposed system, we develop an application system which provides voice playing services for notification of other physicians through our context middleware.

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Development of Energy Harvesting Technologies Platform for Self-Power Rechargeable Pacemaker Medical Device. (자가발전 심장박동기를 위한 에너지 수확 플랫폼 개발)

  • Park, Hyun-Moon;Lee, Jung-Chul;Kim, Byunng-Soo
    • The Journal of the Korea institute of electronic communication sciences
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    • v.14 no.3
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    • pp.619-626
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    • 2019
  • The advances of semiconductor and circuitry technology dovetailed with nano processing techniques have further enhanced micro-miniaturization, sensitivity, longevity and reliability in MID(Medical Implant Device). Nevertheless, one of the remaining challenges is whether power can sufficiently and continuously be supplied for the operation of the MID. Self-powered MID that harvest biomechanical energy from human motion, respiratory and muscle movement are part of a paradigm shift. In this paper, we developed a rechargeable pacemaker through self-power generation with the triboelectric nanogenerator. We demonstrate a fully implanted pacemaker based on an implantable triboelectric nanogenerator, which act as a storage as well as active movement on a large-animal(dog) scale. The self-power pacemaker harvested from animal motion is 2.47V, which is higher than the required pacemaker device sensing voltage(1.35V).

Qualitative Research on Integrated Support Through Health, Medical and Welfare Network - Based on the Experience of 301 Network Service Users in Seoul Northern Municipal Hospital - (보건의료복지 네트워크를 통한 통합적 지원에 관한 질적 연구 - 서울특별시 북부병원 301네트워크 사업 이용자 경험을 중심으로 -)

  • Ha, Ji Seoun;Kim, Jeung Hyun;Lim, Jung Hyun;Kim, Jung Yun
    • Korean Journal of Social Welfare
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    • v.69 no.2
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    • pp.143-169
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    • 2017
  • The purpose of this study was to explore the implications of the integrated support through the 'health - medical - welfare' network and the specific context of the operation through the experiences of the users who participated in the 301 network project of Seoul northern municipal hospital. To do this, In-depth interviews were carried out with 10 research participants. The data was analyzed by general qualitative research methods. As a result of analysis, users lost their willingness because of living in a vicious cycle of poverty and illness before participating in 301 network services, but through the participation of the service, they were able to receive the integrated support of 'cure-care-life stability'. These experiences ultimately led to the regeneration of the will of their lives. At the basis of this experience were operating strategies and conditions such as the formation of a diverse professional team, the establishment of a linkage system within and outside the hospital, the establishment of a treatment linkage system through the acquisition of treatment subsidies, and the linkage of resources at mediation level. As the attempt to integrate 'health, medical and welfare' with well-coordinated strategies and conditions showed the possibility of complementing the limitation of the health welfare support system in Korea, the extension of the related business was suggested. For this, it suggested the more stable stabilization of the linkage system and the improvement of the institutional aspect.

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