• Journal of the Korean Society of Radiology
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• v.81 no.2
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• pp.395-408
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• 2020

Purpose To evaluate the value of clinicopathologic factors and imaging features of primary breast cancer in predicting early recurrence after the primary treatment. Materials and Methods We enrolled 480 patients who had been followed-up after breast-conserving surgery and adjuvant therapy from January 2010 to December 2014 at our hospital. Early recurrence was defined as recurrence within 3 years after completion of primary treatment, and univariate and multivariate logistic regression analyses were performed to determine the clinicopathologic and imaging predictive factors of early recurrence. Results In the univariate analysis, among the clinicopathologic factors, advanced stage (p = 0.021), high histologic grade (p < 0.001), estrogen receptor negative (p = 0.002), high Ki-67 proliferation index (p = 0.017), and triple-negative breast cancer (p = 0.019), and among the imaging features, multifocality (p < 0.001), vessels in the rim on Doppler ultrasonography (US) (p = 0.012), and rim enhancement (p < 0.001) on magnetic resonance imaging of the breast were significantly associated with early recurrence. In the multivariate analysis, advanced stage [odds ratio (OR) = 3.47; 95% confidence interval (CI) 1.12-10.73; p = 0.031] and vessels in the rim on Doppler US (OR = 3.32; 95% CI 1.38-8.02; p = 0.008) were the independent predictive factors of early recurrence. Conclusion Vascular findings in the rim of the primary breast cancer on Doppler US before treatment is a radiologic independent predictive factor of early recurrence after the primary treatment.

• The KIPS Transactions:PartC
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• v.14C no.3 s.113
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• pp.221-228
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• 2007

For the usage of the different standard technology among DRM vendors, the DRM technologies in today could not guarantee the interoperability between the digital contents and digital devices. While users have been guaranteed the protection of contents, they have to put up with the limitation and inconvenience. The Superdistribution methods that InterTrust has proposed is the content distribution technology which is possible to use the content only by the user authentication with the license regardless of the acquisition of the DRM contents. However, it need a additional license with re-authentication from DRM server when the original contents need to be moved to other devices from the own device. In this paper, to reduce the inconveniences of re-authentication and re-issue procedures of the license and continually to protect the rights of contents on the offline, we propose the DRM system that creates domain between home devices and enable users to freely transfer contents with the domain.

• Journal of Korea Multimedia Society
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• v.11 no.11
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• pp.1555-1565
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• 2008

Biometric information such as face and fingerprint information is highlighted in many security areas, including authentication, due to its uniqueness and convenience factors. However, if exploited maliciously, it can cause more serious damage than traditional security measures, like passwords. This paper reviews the watermarking method that is able to verify the integrity of this biometric information. The watermark to be inserted is the date of the biometric information acquisition. It is combined with 16-bit Cyclic Redundancy Checks prior to insertion. In particular, face and fingerprint images are saved in a specific compressed format. The proposed watermarking algorithm will be designed in such a way as to remain resilient against compression. The watermark inserted at the acquisition stage will be extracted at each storage and deployment stage, so that the integrity of the biometric information can be verified.

• Journal of Korean Society of Transportation
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• v.33 no.1
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• pp.100-111
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• 2015

After empirically investigating the vehicle accident risks by age groups, various programs and policies have been imposed to reduce the old's risks in other countries. In Korea, it is little known the risk level by age groups and no policy changes has been implemented even if the number of vehicle accidents occurred by the old has been rapidly rising while the total number of vehicle accidents has been decreasing. This study empirically investigates the vehicle accident risks by age groups and the results show that the old drivers over age 65 has the highest accident risk except for the young drivers below age 25. Thus, we emphasize the necessity of reinforcing the qualifications for reissuing the drive licence and programs for educating the old drivers in Korea which is facing the most rapid population aging in the world. On the other hand, various changes are needed reflecting the old drivers such as reforming the road signs, issuing a sticker and providing them incentives such that the old drivers use the public transportation instead of self-driving.

• The KIPS Transactions:PartC
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• v.13C no.3 s.106
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• pp.359-368
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• 2006

AAA(Authentication, Authorization, Accounting) is the service that offers authentication, authorization, and accounting method, and every terminal that accesses the network requires this AAA service. The authentication process of a mobile terminal is as follows: a mobile phone accesses an authentication server in a home network via the authentication service in an external network, which receives the authentication result. And, for the home authentication server to offer secure service, a unique key is distributed for the secure communication between the external agent and the user, the external agent and the home authentication server, and the user and the home authentication server. This paper discusses and proposes the key distribution for secure communication among external authentication servers when a mobile terminal travels to an external network. As the proposed method does not require the home authentication server to reissue another authentication when a user travels to other external networks, it reduces the overload in the home authentication server. It can also distribute a PIN-driven key.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.2
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• pp.452-458
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• 2021

The value and importance of personal information are increasing due to the increasing number of fields where the Internet environment and computing environment are used, and user authentication technology is also changing. Until now, accredited certificates, which are mainly used in the financial sector, are being replaced with biometric authentication technology due to the problem of revocation. However, another problem is that biometric information cannot be modified once it is leaked. Recently, with the advent of blockchain technology, research on user authentication methods has actively progressed. In this paper, both public certificate and blockchain-based user authentication can be used without system change, and a new DID issuance and reissuance method that can replace the resident registration number is presented. The proposed system can be used without restrictions in a blockchain. However, the currently used DID requires installation of an application at the Interworking Support Center for verification. Since a DID can be authenticated without registering as a member, indiscriminate information collection can be prevented. Security, convenience, and determinism are compared with the existing system, and excellence is proven based on various attack methods, its portability, and proxy use.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.14 no.2
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• pp.85-100
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• 2004

Study and analysis on the digital certification of the world today, and census on how digital signature is being used or considered for the government will be used to sum of what can be the difficulties and Problems in operating digital signature certifications for the government administrations at this research, and of course the answers to these problems will be provided too. This research suggests practical ideas on how to interoperate between Government PKI (GPKI: Administrational Digital Certification for the Government) and National PKI (NPKI: Digital Certification for General Public ＆Business), how to make use of Standard Security APIs, how to manage (e.g. issue, reissue, update, revoke) digital certificate, how to improve technical side of security and reliability, and how to improve political issues on public education for information security. Digital certification will become more popular and widely used in government administrations in the future. Therefore, census and research on demands md satisfactions of digital certification for public and government will be regularly performed. Of course, continuous maintenances and improvement in this field will be necessary to obtain firmer way of information security.

• The Journal of the Korean bone and joint tumor society
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• v.15 no.1
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• pp.13-25
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• 2009

Purpose: The DNA repair protein, $O^6$-methylguanine-DNA methyltransferase (MGMT), removes alkyl adducts from the $O^6$ position of guanine. Epigenetic inactivation of MGMT has been found in human neoplasia and considered one of the implicated factors in chemoresistance. Materials and Methods: Sixty-two patiensts with soft tissue sarcomas (STS) were analyzed for the status of MGMT protein expression by immunohistochemistry and the promoter hypermethylation of the MGMT gene using methylation-specific PCR. Result: The loss of MGMT expression was found in 20 cases (32.3%) of total 62 STS. MGMT promoter hypermethylation rate was 25.0% (11/44 cases). The loss of MGMT expression showed significant association with high AJCC stage, high FNCLCC grade, and aggressive behavior. However,when the group who received chemotherapy was analyzed (n=27), loss of MGMT expression was correlated with worse survival in multivariate analysis (p=0.024). MGMT promoter hypermethylation is associated with high FNCLCC grade. MGMT promoter hypermethylation status had a strong correlation with loss of MGMT expression (p=0.000). Conclusion: Our results suggest that MGMT promoter hypermethylation and loss of MGMT expression had a tendency to be associated with poor prognosis and that loss of MGMT protein expression is frequently occurs via MGMT promoter hypermethylation.

• The Journal of the Korean bone and joint tumor society
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• v.5 no.1
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• pp.70-75
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• 1999

We present a case of parosteal osteosarcoma of the femur with secondary dedifferentiation. This 57-year-old woman was radiologically diagnosed as a parosteal osteosarcoma in 1987. In 1992, excisional biopsy revealed a classical parosteal osteosarcoma with diploidy DNA pattern. In 1998, she revisited due to a recurrent tumor with pathologic fracture. The resected specimen showed a classic parosteal osteosarcoma with area of dedifferentiation, showing high-grade spindle cell sarcoma. This dedifferentiated area revealed aneuploidy cell population on DNA flow cytometry. This case reminds us that not all parosteal osteosarcomas are low-grade lesions. Some low-grade lesions may dedifferentiate to become high-grade tumors after inadequate excision.

• Childhood Kidney Diseases
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• v.15 no.2
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• pp.179-183
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• 2011

Abrupt progression of renal scarring associated with vesicoureteral reflux (VUR) is rare in males over 2 years old of age. We report a 5 year old boy with sustained unilateral high grade VUR who experienced abrupt progression of renal scarring; he had a relative renal radionuclide uptake of 38% at 2 years of age that dropped to 8% after three years. Per his parent's wishes, he took prophylactic antibiotics for 25 months after his first febrile urinary tract infection (UTI) at 4 months old without surgical management. One episode of recurrent breakthrough infection occurred at the age of 2 years. This observation reminds us that a recommending surgical management for sustained high grade VUR associated with renal scarring might be needed. Close follow up of DMSA for renal scanning, and long term follow up of patients after the first febrile UTI are important.