• Journal of the Korean Society of Food Science and Nutrition
• /
• v.22 no.5
• /
• pp.511-516
• /
• 1993

This study was conducted to investigate the biochemical efforts of old antler extracts on the enzyme activities in serum of galactosamine (GaIN)-induced rats. Male rats of Sprague-Dawley strain weighing the average of 110$\pm$10g were divided into four groups and each group was fed either AIN-76 diet or modified AIN-76 diet with old antler extracts (water extract, neutral extract, ether extract) for four weeks. CaIN (400mg/ kg of body weight) was injected to CaIN treatment groups intraperitoneally on the same day every week. CaIN treatment decreased growth performance of rats. But dietary supplementation of old antler extracts prevented this decrement. Serum aminotransferase activities were increased by CaIN treatment, but this increment was reduced by feeding the old antler extracts, and the effect of water extract was the most prominent of the old antler extracts. Activities of lactate dehydrogenase (LDH) and alkaline phosphatase (ALP) in serum of CaIN treatment groups were higher than those of control groups and were decreased by old antler extracts supplementation.

• Proceedings of the KIEE Conference
• /
• 2003.07c
• /
• pp.1442-1444
• /
• 2003

폴리머 애자용 shed 재료의 전기방전에 대한 열화내성과 표면이 오염된 조건하에서도 우수한 발수성 유지는 제품의 장기성능에 있어서 가장 중요한 인자들이다. 내트래킹성 확보를 위한 보강재로는 ATH가 주로 사용되고 있으며 ATH의 첨가량이 많을 수록 내트래킹성은 대체로 향상되는 것으로 되어 있다. 그러나 애자 제조시 무결점 성형성의 만족이 대단히 중요하기 때문에 ATH를 고충진하는 경우 사용하는 process oil들의 종류 및 첨가량을 고려한 ATH 첨가량의 최적화는 필요하다. 본 논문에서는 ATH를 170 part로 다량으로 첨가하면서 화학적 구조와 점도가 다른 몇 가지 실리콘 fliud들을 사용하여 무결점 성형에 적합한 가소도를 갖는 컴파운드를 제조하여 기본물성과 초고압 옥외절연물의 shed 재료로서 장기성능에 영향을 주는 방전열화내성과 표면발수성의 회복특성을 평가하였다. 컴파운드의 성형작업성과 관련이 큰 가소도는 fluid 점도에 따라 상당한 차이를 보이므로 실리콘 fluid 종류의 선택과 첨가량의 최적화에는 성형작업성, 발수성 회복특성, 열화내성 등의 고려가 필요하다. 무결점 애자성형을 위한 진공 사출에서 고무 컴파운드의 가소도가 중요한데 동일한 ATH첨가조건에서 일정한 가소도를 갖게 하는데 필요한 양은 fluid들의 종류에 따라서 상당한 차이가 있었다. 코로나 처리후 발수성 회복특성은 fluid들의 분자크기와 반응기의 종류에 따라 상당히 영향을 받았으며 분자가 클수록 초기회복속도는 다소 느렸지만 평상시에 늘 유지되는 상시발수성은 다소 높게 유지되었다. 아크와 트래킹 방전에 의한 무게 감소는 ATH가 과량으로 첨가되어 상당히 적었으며 fluid의 분자가 크면서 페닐기를 가진 fluid들이 첨가된 고무가 우수한 특성을 보였다.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.33 no.5
• /
• pp.827-831
• /
• 2004

This study was carried out to investigate the supplementary effects of ${\gamma}$-oryzanol on the blood glucose level in diabetic mice. We supplied 2 experimental diets (CO without and GO with 0.2% ${\gamma}$-oryzanol) to diabetic mice for 8 weeks. Diet intake, body weight and levels of blood glucose, hemoglobin $A_{lc}$ and insulin were measured. Though there was no significant difference in diet intake between experimental groups, the concentration of fasting blood glucose and blood glucose area from glucose tolerance test in diabetic mice was lower in GO group than CO group during the supplementary period of experimental diets. Hemoglobin Ai, was lower and serum insulin level was higher in GO group than CO group without significance. These results suggest that r-oryzanol decrease the blood glucose level, and ${\gamma}$ -oryzanol produced from residual product of rice may be developed with high value.

• Korean Journal of Animal Reproduction
• /
• v.23 no.1
• /
• pp.1-12
• /
• 1999

The present study was conducted to find the effects of different cadmium(Cd) levels in diets on clinical toxicity, sperm capacity and histopathological changes in rats. Thirty male rats of Sprague-Dawley weighing 125.3$\pm$15.2g were randomly blocked into five groups according to body weights. Five levels of Cd in AIN-76 purified diet(0, 25, 50, 100 and 250 ppm) had been fed for 8 weeks. Cadmium was supplemented with a form of CdCl$_2$. 1. After 8 weeks of Cd intake had resulted in apparent cadmium intoxication; reduced growth rate, enlarged kidney and testis, decreased hematocrit value and hemoglobin content in response to supplemented Cd levels in the diets. 2. Cadmium accumulation in liver and kidney showed a tendency to increase in cadmium-exposed groups. The levels of metallothionein were also significantly elevated in the tissues of liver in response to the levels of Cd supplemented(P＜0.05). 3. Although sperm motility was not significantly different among treatments, rats fed Cd tended to have reduced sperm motility but sperm concentration of Cd supplemented groups were significantly lower than that of control(p＜0.05). 4. Based on the findings from gross lesion, rats fed 250ppm of Cd were externally emaciated, had exposed penis and observed atrophies of kidney and testis. Histopathological observation seemed that the liver of groups feeding Cd supplemented diets showed cellular degeneration and accumulation of eosinophilic materials in the capillaries. In kidney, rats fed Cd diets had shown tubular epithelium degeneration and lesions of basophilic materials, while testes were weakened in numbers of spermatid and sporadically enlarged of giant cells.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.35 no.10
• /
• pp.1343-1348
• /
• 2006

This study was performed to investigate the effects of silk protein enzyme hydrolysates on blood glucose and serum lipid in db/db diabetic mice. Twelve week-old-male C57BL/KsJ db/db mice were divided into two groups: diabetic control group and 0.25% silk protein hydrolysates solution group, which were fed for 8 weeks. Body weight increased in the silk protein hydrolysates group compared with the diabetic control group. There were no differences in food and water intake between the diabetic control and the silk protein hydrolysates groups. The weight of liver increased in the silk protein hydrolysates group while that of kidney increased in the diabetic control group. The blood glucose level increased about 18.0% in the diabetic control group after 8 weeks while that in the silk protein hydrolysates group increased about 5.8%. Also, silk protein hydrolysates improved the glucose tolerance in C57BL/KsJ db/db mice. There was no difference in total cholesterol and non-HDL cholesterol concentration between the diabetic control and the silk protein hydrolysates group. Triglyceride concentration were lower in the silk protein hydrolysates group than in the diabetic control group (p<0.05) while HDL-cholesterol concentration were higher in the silk protein hydrolysates group than in the diabetic control group (p<0.05). This results suggest that administration of silk protein enzyme hydrolysates reduces significantly an increasing rate of 1]food glucose, decreases triglyceride, and increases HDL-cholesterol in C57BL/KsJ db/db mice.

• Journal of the Institute of Electronics Engineers of Korea SD
• /
• v.41 no.1
• /
• pp.21-28
• /
• 2004

We have demonstrated a low speed weigh-in motion system using FBG sensors and performed field test at a trial road. Technique, called identical chirped grating interrogation, have used for a demodulation relying on the mismatching of two identical broadband chirped gratings. We compensated the fluctuation of LED power and the temperature of sensor and used a lock-in amplifier to reduce effect of noise. We could design a bending plate that the measurement results are independent of position of weight. The FBG sensors weigh-in motion system showed linearity and reproducibility.

• Korean Journal of Food Science and Technology
• /
• v.10 no.2
• /
• pp.151-156
• /
• 1978

Ginseng jellies and candies were prepared by adding Ginseng extracts as final concentration of 0.5% and 1% for jellies and 0.7% for candies. Feeding experiments of the diets containing Ginseng extract were carried out for evaluation in respects of growth rate, feed efficiency ratio, organ weight change, hematocrit value, and blood cholesterol content by feeding rats for 6-week. The results of Ginseng supplemented diets were not significantly different from those for the control. Liver, spleen and kidney cells of Ginseng products feeding rats appeared no abnormalities to compare to the control rats.

• Proceedings of the Korea Contents Association Conference
• /
• 2017.05a
• /
• pp.423-424
• /
• 2017

상황버섯은 오랜 역사와 전통이 있는 소재로서 폴리페놀류가 함유되어 있어 항암, 혈중콜레스테롤 저하, 혈압강하 등의 약리효과가 있는 것으로 알려져 있다. 본 연구에서는 in vivo 실험을 통해 CPA (Cyclophosphamide)로 유도된 면역저하 마우스 모델에서 상황버섯 투여 농도에 따른 cytokine 활성 효과를 확인하여 상황버섯의 면역 증진 효과를 평가하고, 유효한 농도를 선정하여 시제품을 제작하고자 하였다. 연구결과, 림프기관 장기 무게(흉선, 비장, 악하림프절)와 혈청과 비장의 cytokine이 CPA군(CPA control)에 비해 상황버섯 추출물 투여군에서 유의적으로 증가하였다. 또한 실험을 퉁해 선정한 유효한 농도인 50 mg/kg의 농도로 시제품을 제작하였으며, 상황버섯 특유의 떫은 맛을 감쇄하기 위해 아스코르빈산과 NaHCO3을 첨가하여 최적 배합 비율을 선정하여 음료 200 mL당 상황버섯 추출물 55.6 mg (0.0278%), 아스코르빈산 200 mg (0.1%), NaHCO3 60 mg (0.03%)이 함유 되도록 제작하였다. 본 연구 결과 상황버섯추출물은 CPA로 인해 감소된 사이토카인 분비를 상향 조절함으로써 면역저하 상태를 개선시켜 면역 증진 효과가 있는 것으로 판단된다.

• Journal of Food Hygiene and Safety
• /
• v.3 no.2
• /
• pp.83-88
• /
• 1988

Propyl gallate used as an antioxidant was examined for its effects on murine Immune system and metbemoglobin content treated with anillne. As immunotoxicology assay parameters, we adopted circulating leukocytes and immunoorgan weights for pathtoxicology, IgM plaque forming cells and Artbus reaction for humoral immunity. Propyl gallate's effects were observed as follows; 1. Propyl gallate decreased circulating leukocyte counts, dose dependently. 2. Relative immunoorgan weigbts were not affected. 3. Propyl gallate diminisbed IgM PFCs/spleen cell and IgM PFCs/spleen. 4. Propyl gallate decreased Arthus reaction. 5. Propyl gallate did not affect metbemogiobin content treated wltb aniIIne.

• Proceedings of the Korean Radioactive Waste Society Conference
• /
• 2003.11a
• /
• pp.395-400
• /
• 2003

For the long term storage safety study of the metallic spent fuel, U-Nb, U-Ti, U-Ni, U-Zr, and U-Hf simulated metallic uranium alloys, known as corrosion resistant alloys, were fabricated and oxidized in oxygen gas at $200^{\circ}C~300^{\circ}C$. Simulated metallic uranium alloys were more corrosion resistant than pure uranium metal, and corrosion resistance increases Nb, Ni, Ti in that order. The oxidation rates of uranium alloys determined and activation energy was calculated for each alloy. The matrix microstructure of the test specimens were analyzed using OM, SEM, and EPMA. It was concluded that Nb was the best acceptable alloying elements for reducing corrosion of uranium meta] considered to suitable as candidate.