• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.12 no.2
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• pp.194-198
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• 2009

Purpose: Severe abdominal distension is not uncommon symptom in the neonate. Two major causes of this symptom are benign transient intestinal ileus (BTII) and Hirschsprung`s disease (HD). But it is difficult to differentiate BTII from HD based on the symptoms and simple abdominal x-ray findings. The aim of this retrospective study was to assess the clinical aspects and diagnostic tests differencing two diseases. Methods: From August 2004 to March 2009, nineteen patients with severe abdominal distension, who underwent barium enema, anorectal manometry, and rectal suction biopsy (triple tests) due to a suspicion of HD, were enrolled. A comparison of clinical data associated with BTII and HD based on the clinical features and results of triple tests. Results: The age of onset of symptom was between 2 and 6 weeks in BTII and within 3 weeks in HD. On the barium enema, transitional zone revealed in 6 (50%) patients in BTII and 4 (57.1%) in HD. On anorectal manometry, the anorectal inhibitory reflex was present in 11 (91.7%) patients in BTII and 1 (14.3%) in HD. On rectal suction biopsy, ganglion cell was present in 9 (75%) patients in BTII and 0 (0%) in HD. Abdominal distension was improved within 3 months of life in all cases of BTII. Conclusion: We think that anorectal manometry may be more simple and useful diagnostic method than barium enema and rectal suction biopsy for differential diagnosis of transient intestinal ileus and Hirschsprung's disease.

• Journal of Conservation Science
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• v.37 no.2
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• pp.179-189
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• 2021

In this study, the research objects are gilt plated silver-iron nails excavated from the west of the tombs in Neungsan-ri, Buyeo. A gilt plated silver-iron nail was fabricated by combining silver and iron via heating and then gilding amalgam on top of this combination, demonstrating that this ancient artifact that can be replicated using current technology. Since the metal (Au, Ag) surface of these gilt plated artifacts are covered with iron oxide, which slips into the cracks and scratches of the artifacts as well, desalination is essential. Based on the results of the preliminary experiment, the research objects were classified into grades A, B, and C, according to the degree of corrosion and then desalinated using an alkali solution (NaOH, Sodium Sesquicarbonate of 0.1 M) at 60℃. The results demonstrate that the more serious is the degree of corrosion, the more is the amount of Cl^- detected. Further, more Cl^- was released when NaOH was used than when sodium sesquicarbonate was used, for all grades except Grade A. Furthermore, the more serious is the degree of corrosion, the longer is the desalination period and the reaction with NaOH for all grades except Grade A. A comparison of the Fe composition of the surface before and after desalination shows that Fe composition is the use of NaOH resulted in a smaller increase compared with the use of sodium sesquicarbonate, for all grades except Grade B. However, four of the nails were damaged owing to NaOH (Grade B 3ea, Grade C 1ea) during desalination. Thus, Cl^- ions are more stably released when sodium sesquicarbonate is used than when NaOH is used.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.7 no.1
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• pp.40-47
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• 2004

Purpose: A new classification of gastrointestinal food allergy was published, but the changes of terminology between previously reported terms and the new ones were in a state of disorder. This has resulted in confusion between medical communication and diagnostic and therapeutic approaches. The clinical observations of infants presenting with gastrointestinal cow milk allergy (GI-CMA) were performed, and the changes in the terminology reviewed through the published Korean literature. Methods: Between March 2003 and July 2003, data from 37 consecutive infants with GI-CMA, aged 2 weeks to 15 months, were reviewed. The challenge and elimination test of cow milk, and the endoscopic and histologic findings, were used for the seven subdivisions of GI-CMA according to a new classification on the basis of patients' ages, clinical manifestations and location of gastrointestinal lesions. Results: The 37 patients had a mean age of $5.4{\pm}4.8$ months, with those observed in 26 (70.3%) of patients being below 6 months of age. The seven final diagnoses were; cow milk protein-induced enterocolitis (CMPIE) in 12 (32.4%), cow milk protein proctitis (PROC) in 12 (32.4%), IgE-mediated (IGE) in 6 (16.2%), gastroesophageal reflux-associated cow milk allergy (GERA) in 5 (13.5%) and eosinophilic gastroenterocolitis in 2 (5.4%). CMPIE was revealed as the typical type in 7 (18.9%) and the atypical type in 5 (13.5%), and all of typical CMPIE revealed cow milk protein-induced enteropathy. The mean age at symptom onset was $4.3{\pm}0.8$ months, and for those with typical and atypical CMPIE, and PROC and GERA were $3.8{\pm}4.6$, $10.4{\pm}3.8$, $3.4{\pm}3.9$ and $7.8{\pm}5.7$ months, respectively (p<0.05). The period from onset of symptom to diagnosis was $2.4{\pm}3.3$ (0.5~12) months, with those observed in atypical CMPIE and GERA being over 3months. Although the birth weights in all patients were within the 10~90 percentile range, the body weights on diagnoses were below the 3 percentile in 48.6%; IGE 16.7%, EOS 0%, typical CMPIE 85.7%, atypical CMPIE 60.0%, PROC 25.0% and GERA 100% (p<0.05). Through the review of the Korean literature, 8 case reports and 14 original articles for GI-CMA were found. Conclusion: GI-CMA is not a rare clinical disorder and is subdivided into seven categories on the basis of the patient's age, clinical manifestations and location of the gastrointestinal lesions. The terms for GI-CMA are changing with new classifications, and careful approaches are necessary for medical communications.

• Journal of Korean Society of Transportation
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• v.23 no.6 s.84
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• pp.55-67
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• 2005

There are 24 airways in Incehon IFR, including 11 domestic routes and 13 international routes. The airways designated by ministry of Transportation and Construction are the routes for aircraft to fly being serviced by air traffic control system for flight safety. This study reviewed safety situation of existing permanent airways within Incheon IFR and temporary airways connecting North and South Korea. The study tried to identify the problems related to airway operation and to suggest solutions to the questionable area. The main findings are as follows: It is necessary to improve the existing normal airway systems and enlargement of the route. The airway A593 has to be upgraded to normal route. The temporary airways established to connect Seoul and Pyongyang also needs to be upgraded by air traffic control transfer agreement between two Koreas.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.14 no.1
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• pp.1-6
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• 2000

In this paper, organic dispersion type back light EL(Electroluminescent) devices were manufactured using Ethyl hydroxy ethyl cellulose as organic binder, ZnS:Cu as phosphor powder and $BaTiO_3$ as dielectrics by screen printing method, which are focused on as a new light source. The properties of the fabricated organic dispersion type back light EL devices were showed $1.98[mA/\m^2]$ of current density, 0.075[W] of power consumption, 7.1[nF] of capacitance at $25[^{\circ}C]$, 100[V], 400[Hz], respectively. Also brightness of the fabricated device was revealed $20~110[cd/\m^2]$ at 50~150[V] and the change of color was shoed bluish green of x=0.1711, y=0.3676 which are color coordinate by CIE.

• YAKHAK HOEJI
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• v.52 no.2
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• pp.93-100
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• 2008

A liquid chromatographic method with tandom spectrometric detection (LC/MS/MS) for the simultaneous determination of doxifluridine and its active metabolite, 5-fluorouracil (5-FU) was developed over the concentration range of $5{\sim}2000$ ng/ml, respectively. Doxifluridine, 5-FU and internal standard, 5-chlorouracil (5-CU), were extracted from liver and intestine tissue via protein precipitation. Acetonitrile was used as the extraction solvent and the supernatant was evaporated and reconstructed in mobile phase. Optimum chromatographic separation was achieved on a Agilent Zorbax $C_{18}$ ($100\;mm{\times}2.1\;mm$, $3.5\;{\mu}m$) column with mobile phase run in isocratic with methanol : water (20 : 80, v/v). The flow rate was 0.2 ml/min with total cycle time of 5 min. The lower limit of quantification was validated at 5.0 ng/ml of liver and intestine tissue, for both doxifluridine and 5-FU, respectively. The intra-day and inter-day precision and accuracy of quality control (QC) samples were <11% coefficient of variation and <7% relative error from theoretical concentration for both analytes. In addition, the special designed stability study was performed, because the metabolism of doxifluridine occurs spontaneously even in ice bath for monkey liver. The stability of doxifluridine in liver and intestine of monkey and beagle dog was compared. It was found that bioanalytical validation could not be performed for the monkey liver; however, beagle dog's liver has relatively low speed of metabolism compared to monkey liver and instead of monkey liver, beagle dog's liver could be used for the validation. Bioanalytical validation could be performed in monkey intestine. Eventually, this developed method for liver and intestine will be useful in support of the toxicokinetic and pharmacokinetic studies of doxifluridine and 5-FU.

• 한국벤처창업학회:학술대회논문집
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• 2019.11a
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• pp.15-20
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• 2019

2019년 3월 기획재정부 장관은 관계부처 합동으로 제2벤처 붐 확산전략을 발표하였다. 신산업 고기술 스타트업 발굴을 통해 기술인재 고기술창업 특히 대학 및 연구소등의 우수 인재가 기술혁신형 창업을 하고, 이에 투자 멘토링 기술 지원하는 사업을 강화하는 한편 지원규모를 확대한다는 계획이다. 2019년 9월 국내 벤처기업 수는 3만6759개이고, 액셀러레이터 투자도 벤처투자로 인정한 '벤처기업육성에 관한 특별조치법' 개정안을 마련하고 있으며, 엑설러레이터 기준을 새로 마련하고 있다. 벤처 투자액은 올해 4조원을 돌파할 거라 예상하고 있는 가운데, 특히 창업의 마중물 역을 하는 액셀러레이터 시장이 크게 성장하고 있다. 대학부터 지자체, 기업, 기존 투자사들까지 뛰어들면서 관련제도가 도입된 지 3년이 채 되지 않아 200곳이 설립됐다. 전 세계적인 스타트업 붐에 더해 진입문턱이 대폭 낮아지자 초기 기업에서 기회를 엿보는 곳들이 늘어난 것으로 보인다. 2017년 54곳에 불과했던 액셀러레이터는 2년이 지나지 않아 4배 가까이 증가했다. 이처럼 시장이 급성장하는 이유는 대기업 중심의 경제 성장세가 둔화되고 우버와 같은 회사들이 새로운 산업을 구축하며 전 세계적으로 스타트업에 대한 관심이 고조되었고, 정부 역시 제2벤처 붐을 일으키겠다며 다방면의 벤처 육성책을 내놓고 있기 때문이다. 이러한 엑셀러레이터에 대한 관심은 학술적이 연구로도 나타나고 있는 바, 엑셀러레이터로부터 투자를 유치한 스타트업의 성과와 관련하여 다양한 원인을 찾고자하는 노력이 시도되고 있다. 스타트업 관계자가 인식하는 엑셀러레이터의 평가지표에 대한 수용성 정도와 그들의 성과 간의 관계에서 엑셀러레이터 조직에 대한 신뢰의 역할을 연구할 필요성이 제기된다고 할 것이다. 제기된 연구 필요성의 해결을 위하여 본 연구에서는 최근 3년 이내 엑셀러레이터로부터 투자 유치를 받은 스타트업 관계자를 대상으로 평가수용성과 엑셀러레이터의 조직신뢰 그리고 성과에 대한 설문조사를 실시하였다. 본 연구의 분석결과를 바탕으로 스타트업 성과를 극대화할 수 있는 엑셀러레이터의 평가지표 구성과 조직측면에서 전략적 방안 모색의 기초자료로 제공하고자 한다.

• Journal of the Korean Society of Marine Environment & Safety
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• v.28 no.1
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• pp.47-53
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• 2022

A person who intends to become a maritime pilot shall have sea experience as a master, pass the apprentice pilot test and pilot test, and obtain a license from the Minister of Oceans and Fisheries. In Korea, the government limits the number of pilot licenses, considering the demand for pilotage. An inherent problem exist in the apprentice pilot test system as it conducts a relative evaluation based on test scores without an absolute evaluation standard. The purpose of this study is to identify problems of the current pilot test system and to suggest ways to improve the pilot certification system. In this study, the history of amendments of the pilot certification system in the Pilotage Act was investigated, and implications were derived by examining international standards for pilot certification, and a survey was conducted on 77 incumbent pilots. Consequently, a plan to improve the domestic apprentice pilot test and a step-by-step implementation plan for pilot certification system improvement were presented. The results of this study are expected to be utilized not only for the development of the government policy on pilot certification and for related academic basic data.

• The Journal of the Korea Contents Association
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• v.11 no.6
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• pp.419-427
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• 2011

As for the anti-terrorism bills, which were submitted to the National Assembly, the mobilization of anti-terrorism commando, which was designated or established by the National Defense Minister, is mobilized the military troops without being based on marital law in light of the constitutional law, thereby possibly violating the constitution, first of all, with regards to mobilization of anti-terrorism commando, which was formed with military troops. The anti-terrorism commando is the military force, which was trained professionally for the anti-terrorism activity. Thus, the violation of human rights may be greatly reduced rather than what general soldiers are putted in the public-order activity such as anti-terrorism. However, it is thought to be desirable to make it possible for the input of special forces, which were trained professionally in relation to anti-terrorism activity, through constitutionally revising the constitutional law. As for the provision of 'support for military troops' in the anti-terrorism bill, what is a case that the nation's important facilities and multi-use facilities are difficult to be protected from terror with the anti-terrorism commando and police force needs to be constitutionally regarded as resulting in reaching the level enough to correspond to 'a state of national emergency equivalent to wartime incident.' Thus, enacting the future anti-terrorism law, it is thought to be unnecessary for having the provision of 'support for military troops' with receiving criticism obstinately for possibly violating the constitution.

• Journal of Dairy Science and Biotechnology
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• v.15 no.1
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• pp.33-44
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• 1997

We investigated the immunological function of cheese whey protein concentrate (CWPC), which is a by-product of cheese production, using mitogenic activity in murine splenocytes as an index. A fraction isolated by gel filtration and anion exchange chromatography of CWPC showed high mitogenic activity, comparable to the activity of lipopolysaccharide (LPS). The fraction was detected as a single band on SDS-PAGE. It contained calcium, inorganic phosphorus, and carbo-hydrate, indicating the active component to be a glycophosphopeptide (GPP) Since pronase digestion of GPP did not reduce its mitogenic activity, carbohydrate rather than peptide may be important in the activity, When applied on an anti-${\beta}$-caseinophosphopeptide (${\beta}$-CPP ) antibody affinity column, the GPP was separated into two components, one with affinity to ${\beta}$-CPP and the other without such affinity. Both the components contained N-linked oligosaccharide chains and had the mitogenic activity. These results demonstrate that cheese whey contains a GPP having strong mitogenic activity