• Sleep Medicine and Psychophysiology
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• v.7 no.2
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• pp.115-119
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• 2000

Objectives Summary: A 20-year-old man was presented with a history of difficult waking for 10 years. He suffered from morning headache, chronic fatigue and mild daytime sleepiness but had no history of irresistible sleep attack, cataplexy, hypnagogic hallucination or sleep paralysis. Methods: Night polysomnography (PSG), multiple sleep latency test (MSLT) and HLA-typing were carried out. Results: The PSG showed short sleep latency (4.0 min) and REM latency (2.5 min), increased arousal index (15.7/hour), periodic limb movements during sleep (PLMS index=8.1/hr) with movement arousal index 2.1/hr and normal sleep efficiency (97.5%). The MSLT revealed normal sleep latency (15 min 21 sec) and 4 times sleep-onset REM (SOREM). HLA-typing showed DQ6- positive, that corresponded at the genomic level to the subregion DQB1*0601, which was different from the usual locus in narcolepsy patients (DQB1*0602 and DQA1*0102). Conclusion: Differential diagnosis should be made with circadian rhythm disorder and other causes of primary waking disorder. The possibility of a variant type of narcolepsy could be suggested with an unusual clinical manifestation and a new genetic marker.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2003.09a
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• pp.43-43
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• 2003

목적 : 남, 여 ADHD 환자에서 뇌 혈류상태의 차이점을 알아보기 위하여, 다른 정신과적 질환이 없는 ADHD 환자의 SPECT 뇌혈류 영상에 대하여 SPM을 통한 뇌 혈류상태의 차이점을 비교분석하였다. 대상 및 방법 : 남자 ADHD 환자군 51 명 (4-11세, 평균 9.0세)과 정상군 8명(6-17세, 평균, 9.6세) 그리고, 여자 ADHD 환자군 13명(6-12세 평균 9.0세)과 정상군 4 명(6-12세 평균 9.0세)의 SPECT영상을 비교분석하였다. 방사성의약품 $^{99m}$ Tc-ECD 0.33mCi/kg을 환자의 정맥내에 주사하고 30분후 잠을 재운상태에서 Multi SPECT3 camera를 이용하여 영상을 기록하였다. Matlab을 이용한 SPM program에서 남여별 ADHD환자의 뇌혈류지도 영상을 비교하였으며, BOLD(blood oxygenation level dependent effect) data plotting을 이용하여 혈류증가율과 감소율을 분석하였다. 결과 : 1) 남자 ADHD환자군의 혈류증가부위의 경우, P<0.02 에서 대상회전 (cingulate gyrus)이 나타나 P<0.05까지 한 부위에서만 나타났으며, 정상군에 비하여 15.61%의 혈류증가율을 나타내었다. 혈류감소부위로는 P<0.004에서 좌측 대뇌 도이랑 (insula gyrus), P<0.005에서 우측 대뇌 측두엽이랑, P<0.007에서는 우측 대뇌 전두엽아래이랑에서 각각 감소되었으며 P<0.01에서는 좌측 대뇌 전두엽 아래이랑에서도 나타났다. ADHD 환자군은 정상군에 비하여 각각의 클러스터에서 평균 14.97-15.28%의 혈류 감소율을 보였다. 뇌 혈류의 증가율과 감소율은 유의 수준변화에 영향을 받지 않았다. 2) 여자 ADHD환자의 혈류증가의 경우 P<0.003에서 소뇌 후엽 중앙부위, P<0.005에서는 좌측 대뇌 변연엽, P<0.009에서는 좌측 대뇌 측두엽 그리고 P<0.02에서는 소뇌 후엽을 비롯하여 9개부분에서 혈류증가 클러스터가 나타났으며, ADHD환자군은 정상군에 비하여 24.68-31.25%의 혈류증가율을 나타내었다. 혈류감소를 나타낸 부위로는 P<0.001에서 좌측 대뇌의 렌즈핵(lentiform nucleus), P<0.003에서 우측 대뇌의 렌즈핵 그리고 P<0.005에서 P<0.01까지 좌측 대뇌 측두엽중심에서 나타났다. 각각의 클러스터에서 평균 혈류감소율은 30.57-30.84%이었다. 결론 : 남여ADHD 환자의 혈류 증가와 감소부위는 서로 일치하지 않았으며 여자의 경우 혈류 증가와 감소율이 남자보다 더 크게 나타나, ADHD환자의 SPECT를 이용한 분석에서 남여환자를 동시에 분석하는 것 보다는 남여환자를 구분하여 실시하는 것이 더욱 정확한 진단정보를 제공할 수 있다고 판단된다.

• Journal of Sericultural and Entomological Science
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• v.29 no.2
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• pp.7-14
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• 1987

Extensive studies were undertaken to analyze the genetic basis of economically important quantitative characters in the silkworm by diallel crosses of four inbred lines differing widely in silk yielding ability. Some differences between the reciprocal corsses were detected in cocoon weight, cocoon shell weight, cocoon filament length and cocoon filament weight in case the parental lines were greatly differenent each other in silk yielding ability. The general combining ability (GCA) varied with the inbred lines and M242, a Chieese sexlimited larval marking variety showed high GCA value in the economic characters, such as cocoon yield, cocoon weight, cocoon filament length and weight, and raw silk percentage. The highest heterosis effect, about 13% to 14% was seen in cocoon and raw silk yield and it was low in cocoon reelability and raw silk percentage with less than 1%. It is advisable to improve highly heritable quantitative characters such as larval duration, cocoon shell weight, cocoon filament length and raw silk percentage by means of selection, and to select single crosses with high heterosis effect for cocoon weight and cocoon yield which show overdominance. Genetic correlation should be considered when more than two characters are targets for improvement and selecting high cocoon shell weight is effective to breed high silk yielding varieties. It is difficult to improve cocoon reelability because of low heritability (0.11) and its negative correlation with cocoon-silk quality.

• Journal of Sericultural and Entomological Science
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• v.13 no.2
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• pp.119-122
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• 1971

The following results were obtained through the experiments and study of fertility for silkworm eggs in vagina, oviduct, and ovarial base. The sample eggs were collected after leaving silkworm moth for one week from the date of treatment was given to oviporm orifice of the silkworm moth by heated needle in order to discontinue laying eggs. Those sample silkworm moths were divided into two groups. The first group was under the condition of immediately after the couplation and the second group was under the condition of after the laying eggs in some extend, and both of them were completed couplation. The sample eggs were screened in order to confirm the degree of color which normally be observed as very characteristic during hibernating. 1. About 5% of silkworm out of the total sample were identified as having 1-2 eggs. (See table 1). But, the charasteristic colour of hibernating egg was not observed. The colour was not much different as that of eggs in ovarian duct. 2. Immediately after the couplation, the eggs were not found in vagina under the condition of immediately after the couplation. 3. About 10% of the sample under the condition of after laying eggs in some extend were found having eggs in vagina or oviduct. 4. About 2% of the sample silkworm moth under the condition of immediately after the couplation were found having I fertilized egg in oviduct. 5. No fertilized egg was found in ovarian tube. It seemed that sperm did not enter ovarian tube. 6. Almost the entire eggs were found in ovarian tube under the condition of immediately after the couplation. But, eggs under the condition of after laying eggs in some extend were found around oviduct and vagina due to the continuous movement of silkworm eggs towards oviporus orifice. 7. Sperm is mainly found around seminal receptacle and vagina, and sperm goes into micropyle together with silkworm eggs which were moving towards oviduct.

• Journal of Sericultural and Entomological Science
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• v.18 no.1
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• pp.1-5
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• 1976

This work was carried out to investigate how the effects on the growth af branches and the yield of mulberry leaves are shown, when two of each dwarf and normal branches are thinned out in sumner or early autumn. The results obtained are summarized as follows. 1) In mulberry trees after spring pruning: in case of thin out branches in summer and harvest in autumn (42 days after treatment), (1) The average length of branches in thin out trees showed 19% increase by autumn, which turned out to be 11% higher than that of non-thin out did (8%) (2) The thin out treated mulberry trees presented 9% increase in total yields of summer and autumn, when compared with those of the non-thin out trees. 2) In mulberry trees after sumner pruning: in case of thin out branches in early autumn and harvest either in autumn (15 days after treatment) or in late autumn (28 days after treatment), (1) The average length of branches showed about 6∼7% and 8%, intercase by autumn and late autumn, respectively. Thus no effects of thin out treatment could be recognized in growing of branches. (2) The thin out treated mulberry trees presented about 6% increase in total yields of early autumn, showing no significance through, when compared with those of ron-thin out treatment. Whereas the total yields of early autumn and late autumn showed 12% increase with significance at the level of 5% by thin out treatment. (3) As above mentioned, the thin out of mulberry branches brought about a good effect on yields of mulberry leaves, though less on average length of branches. It may be considered that the thin out treatment makes improve the living condition in mulberry trees and in turn induces photosynthesis actively, which results in increase the weight of leaves.

• Korean Journal of Environmental Agriculture
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• v.17 no.3
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• pp.211-214
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• 1998

Changes in physico-chemical properties and major nutrient contents were investigated in the soil of paddy fields during fallow period. Weed vegetation change in the fallow paddy fields was also examined. As the fallow period became longer, organic matter content in the paddy soil has gradually increased. Soil pH of the paddy fields has not changed until three years of fallow period and thereafter slightly increased. Cation exchange capacity of the paddy soil, and exchangeable N, K, Ca and Mg contents in the soil tended to decrease until three years of fallow period and then increase with the prolonged fallow period. As the fallow period became longer, available $P_2O_5$ content in the paddy soil has continuously decreased. Available $SiO_2$ content in the paddy soil has not changed until three years of fallow period and thereafter increased. The vegetation in the fallow paddy fields have mostly been occupied by the weeds of the Gramineae, Cyperaceae, and Compositae. As the fallow period became longer, the weeds of the Polygonaceae and Juncaceae have increased, whereas the weeds of the Leguminosae, Commelinaceae, Pontederiaceae, and Onagraceae have gradually disappeared. However, the weeds of the Gramineae and Cyperaceae have always been dominant in the paddy fields during the fallow paddy period.

• Weed & Turfgrass Science
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• v.7 no.1
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• pp.15-21
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• 2018

Since sulfonylurea (SU) herbicide-resistant Monochoria korsakowii in Seosan reclaimed land in 1998 was reported first, herbicide-resistant weed species and their area of occurrence have been steadily increasing. In recent years, Sagittaria trifolia resistant to SU herbicides has been reported in Gimhae, Gyeongnam province. While collecting S. trifolia for constructing barcode database of major weeds we were suspicious by the continuous variation in the leave morphology of the species. In order to identify the S. trifolia from S. aginash we barcoded the species collected from domestic using ITS and compared the sequence variation with the ITS sequences of S. aginash downloaded from NCBI. As a result, it was found that the plants collected from the domestic did not have any variation among individuals although they showed wide morphological variation. On the other hand, interspecific variation between S. trifolia and S. aginash was 4.6%. Plants that are difficult to identify using morphological characters can be identified quickly and accurately using the barcode technique. Herbicide-resistant weeds may require different management practices depending on the species even in the same genus. Domestic herbicide-resistant weeds are steadily increasing. Therefore, accurate identification of these species must be preceded for effective weed control.

• Journal of Sericultural and Entomological Science
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• v.31 no.2
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• pp.82-90
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• 1989

Antheraea yamamai vitellin was purified from matured eggs by polyacrylamide gel electrophoresis for characterization of its biochemical properties : molecular weight, sugar and lipid composition, amino acid composition and electron microscopic morphology, etc. 1. A yamamai vitellin was composed of two subunits, large and small, showing different mobility in SDS-polyacrylamide gel electrophoresis. 2. The molecular weight of the vitellin was estimated to be approximately 450,000 dalton and the large and small subunits were 174,000 dalton and 44,000 dalton, respectively. 3. The vitellin seemed to be a glycolipoprotein since it showed a positive reaction to coomassie brilliant blue, sudan black B and PAS staining. Both subunits were similiar in this aspect. 4. Lipid of the witellin reveraled several different types including saturated lipids. 5. When the vitellin was incubated at 7$0^{\circ}C$ for 60 minites its apoprotein still cross-reacted to the specific antiserum to the native vitellin. Its sugar components were also detected by PAS staining, but its lipid portion was not detected by sudan black B staining. 6. Its amino acid composition was similar to that of other insects, but its glycine content was peculiarly very high. 7. The vitellin molecule was spherical in shape with a diameter of 14$\pm$0.8nm by negatively.

• Journal of Sericultural and Entomological Science
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• v.48 no.1
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• pp.25-27
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• 2006

[ ${\alpha}-Glycosidase$ ] inhibitors slows the velocity of the uptake of monosaccharides in the small intestine by retarding the speed of degradation of disaccharides to monosaccharides, which made it possible to develop ${\alpha}-glycosidase$ inhibitors as the antihyperglycemic ('antihyperglycemic' means 'blood-glucose-level-lowering') reagent for the diabetic patients such as acarbose and miglitol. Twenty kinds of ${\alpha}-glycosidase$ inhibitors have been reported to exist in mulberry, Morns alba, and some of them are also found in the silkworm, Bombyx mari, as the result of its daily feeding of mulberry leaves as the sole diet. 1-Deoxynojirimycin (DNJ), one of the most potent ${\alpha}-glycosidase$ inhibitor, is the most abundant among polyhydroxylated alkaloids with ${\alpha}-glycosidase$ inhibiting activity in both M alba and B. mari, therefore considered the antihyperglycemic criterion of the mulberry- or silkworm-based neutroceutical products. DNJ is thought to be accumulated in the body of silkworm because the its concentration in the silkworm body is two to three times as much as that in the mulberry leaves. Eighteen silkworm F1 varieties have been recommended for industrial rearing in Korea by some standards such as pathological strength. DNJ concentration in 18 recommendedwere measured at 3rd day in the 5th instar after lyophilization to determine the varieties that accumulates DNJ in its body most. GeumOk-Jam was the highest in the DNJ concentration of 5.45 mg/gDW among the recommended F1 varieties.

• Geophysics and Geophysical Exploration
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• v.10 no.1
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• pp.37-43
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• 2007

The MH21 Research Consortium has conducted a high-resolution 3D seismic survey and a seafloor geochemical survey, to explore methane hydrate reservoirs in the eastern Nankai Trough, offshore Japan. Excellent geological information about shallow formations was obtained from the high-resolution 3D seismic survey, which was designed to image the shallow formations where methane hydrates exist. The information is useful in constructing a geological and geochemical model, and especially to understand the complex geology of seafloor, including geochemical manifestations and the structure of migration conduits for methane gas or methane-bearing fluid. By comparing methane seep sites observed by submersibles with seismic sections, some significant relationships between methane hydrate reservoirs, free gas accumulations below the seafloor, and seafloor manifestations are recognised. Bathymetric charts and seafloor reflection amplitude maps, constructed from seismic reflections from the seafloor, are also useful in understanding the relationships over a vast area. A new geochemical seafloor survey targeted by these maps is required. The relationships between methane hydrate reservoirs and seafloor manifestations are becoming clearer from interpretation of high-resolution 3D seismic data. The MH21 Research Consortium will continue to conduct seafloor geochemical surveys based on the geological and geochemical model constructed from high-resolution 3D seismic data analysis. In this paper, we introduce a basis for exploration of methane hydrate reservoirs in Japan by fusion of 3D seismic exploration and seafloor geochemical surveys.