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A study on absorbing the Cr (Ⅵ) in the body and clearance (크롬(Ⅵ)의 체내 흡수와 소실속도에 관한 연구)

  • 김현영;이성배;이권섭;정용현;한정희;최종윤;김성화;김무강;이용묵
    • Proceedings of the Korea Society of Environmental Toocicology Conference
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    • 2003.10a
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    • pp.182-182
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    • 2003
  • 1.연구목적 : Cr $O_3$은 금속 도금용, 페인트 둥에 많이 사용되며 독성이 강하여 그동안 근로자 건강장해 및 직업병 사례가 많이 발생하였다. 그러나 산화크롬의 흡입에 의한 연구자료는 매우 부족하다. 이에 흡입챔버를 이용 Rats에 흡입노출을 통하여 유해성을 평가하고 각 장기에 흡수되는 크롬의 농도평가와 회복기간에 따라 각 장기별로 흡수된 크롬의 소실속도 둥을 연구하였으며 더불어 회복기간과 제거율의 상관관계 및 체내 반감기 등을 연구하였다. 2. 연구방법 : Cr $O_3$를 폐내 침착율 및 흡수율이 높은 0.5~5$\mu\textrm{m}$ 크기의 aerosol형태로 SD Rats 수컷에 전신폭로 하였다. 노출농도는 0.00, 0.20, 0.50, 1.25mg/㎥(Cr)으로 하여 1일 6시간, 주 5일, 13주간 반복 노출하였고 회복군은 시험물질 종료일을 기준으로 2주, 8주 경과 후 조직장기와 전혈, 혈장 및 적혈구내, 뇨 중 각각의 크롬농도를 분석하였으며 혈액 및 혈액 생화학적 검사도 병행하였다 3. 연구결과 : 혈액검사에서 0.20, 0.50 mg/㎥ 농도군 실험동물의 RBC와 HGB, HCT 둥은 감소의 경향을 보였으나 농도 의존적이지는 않았다. 신장의 절대중량은 대조군에 비해 유의하게 (p<0.05) 감소하고 폐장의 경우는 대조군에 비해 유의한(p<0.05) 절대중량 증가를 보였다 시험물질 노출 후 혈액 중 전혈, 혈장, 적혈구의 회복기간(x)별 크롬농도(y)의 소실속도 상관계수 (노출농도 0.50mg/㎥군의 경우)는 y = 66.51 $e^{0.057}$x/, y = 67.2 $e^{0.101}$x/, y = 70.01 $e^{0.030}$x/, 반감기는 12.0, 6.86, 23.0 일이고 폐장, 간장, 신장의 회복기간(x)별 크롬농도(y)의 소실속도 상관계수 (노출농도 0.50 mg/㎥군의 경우)는 y = 1808 $e^{0.004}$93x/, y = 12.02 $e^{0.029}$7x/, y = 67.61 $e^{0.029}$2x/ 반감기는 140.6, 23.3, 23.7 일로 평가되었다. 4. 고찰 : 실험동물의 전혈, 혈청, 뇨에서의 크롬농도와 시험물질 노출농도는 밀접한 상관을 가졌으나 농도에 정비례하지는 않았다. 뇨 중 흡수된 크롬의 경우 회복기간 초기 (12시간 내)에 대부분 배설이 일어나는 것으로 나타났다. 폐장이 간장, 신장 등 다른 장기에 비해 높은 축적량을 보였으며 축적된 크롬농도가 높을수록 크롬의 소실속도는 현저히 저하하는 경향을 보였다. 노출농도가 높을수록 각 장기조직 내 크롬의 소실속도 (clearance)는 크게 감소경향이 있었으며 이는 체내 과부하시 자정작용이 감소하는 것으로 판단되었다. 본 연구 결과 SD rat를 이용 반복흡입노출의 경우 생체의 무유해영향농도 (NOAEL)는 0.2mg/㎥이하이며 발암물질을 감안하여 안전계수를 100으로 할 경우 사람에 대한 NOAEL은 0.002mg/㎥이하로 판단되었다. 특히 호흡기와 폐장에 강한 유해성을 나타내는 것으로 확인되었다. 것으로 확인되었다.

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Survey on the Changes of Potassium and Magnesium Concentration according to the Retention Time After Rinse of Sucrose and Glucose in Oral (구강 내 자당 및 포도당 잔류 경과 시간에 따른 칼륨과 마그네슘 농도 변화)

  • Lee, Hye-Jin;Yang, Dal-Nim
    • The Journal of the Korea Contents Association
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    • v.19 no.11
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    • pp.424-433
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    • 2019
  • The purpose of this study was to evaluate the salivary concentration of Potassium and Magnesium cations and their variation before and after sucrose and glucose rinse, and to investigate the relationship between the levels of each compound. Saliva samples were obtained from 40 subjects before and up to 60 min after intake of a 10% sucrose and glucose solution at 1-month intervals. Potassium and Magnesium in human saliva were determined via anion-exchange chromatography with an anion-suppressed conductivity detector using 12 mM sulfuric acid. The concentrations of Potassium and Magnesium before sucrose rinse were 274.3±77.9 mg/ℓ and 4.5±2.5 mg/ℓ, also, the concentrations of Potassium and Magnesium before glucose rinse were 279.2±62.1 mg/ and 4.8±2.0 mg/ℓ, respectively. Potassium and Magnesium concentrations were significantly decreased (p<0.05) after sucrose rinse. The content of potassium and magnesium in saliva before and after rinsing sucrose and glucose is difficult to standardize or classify, as previous research. The reason for the variation between individuals is large, and easily changed by chemical or physiological stimulation. However, this study was experiment for the purpose of accumulating basic data for saliva.

Introduction of Water Quality Management in Korean Pond Ecosystems (국내 연못생태계의 수질관리)

  • Hwang, Soon-Jin;Kim, Han-Soon;Cheon, Se-Uk;Lee, Jea-An;Kim, Chang-Muk;Shin, Jae-Ki
    • Korean Journal of Ecology and Environment
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    • v.39 no.4 s.118
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    • pp.508-515
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    • 2006
  • This study was conducted from July to December 2004, in order to find measures to improve the water quality and the function of pond ecosystems which are often negatively affected by phytoplankton and suspended particle matters. Most of the time, the management of ponds in Korea does not consider the ecological concepts such as self-purification and nutrient recycling. Instead, conventional methods depend on other factors such as fish farming and the function of fountains and waterfalls. Sustainability of pond ecosystems must be studied with the highest emphasis given to water quality. Water discharges of inflow and outflow as well as balance adjustment for different factors must be thoroughly studied. There is a great need for studies on sustainability because it can be realized through the horizontal or vertical balances of an ecosystem. Our current research offers useful information to the academia and public on maintaining sustainability in terms of structure and function of the pond.

A Study on the Wise Use and the Management of Intertidal Environment - With Focus on Kanghwa island mudflat by satellite image interpretation and sediment analysis - (조간대 지역의 올바른 관리 및 이용방안에 관한 연구)

  • Park, Eui-Joon;Seo, Jong-Chul
    • Journal of the Korean association of regional geographers
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    • v.7 no.2
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    • pp.82-96
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    • 2001
  • The purpose of this study is to investigate the wise use and the management of intertidal environment. For tills purpose, we selected the Kanghwa island mudflat which is one of the most important intertidal region in Korea peninsula. The main research method is surface sediment and several map analysis. The results are as follows. (1) The study area is worldwide coastal wetland in view of ecology and geomorphology. But most of the salt marsh has been reclaimed since Japanese colonial period, the study area is mainly composed of mudflat. (2) The mean tidal regime of study area is 7.3m. From this tidal regime, the study area is subdivided into four distinct areas: the high intertidal area the middle intertidal area the low intertidal area and the shallow sea area terrestrial area near mudflat. (3) The mean particle size of surface sediment is sand 41.5%, silt 47.3%, clay 11.2%. This particle size pattern indicates the ecological characteristics of surface sediment of the study area. The proportion of clay is increasing to the open sea. (5) The pursuit of the wise use and the management must be implemented by the consideration of not only ecologic and sedimentary characteristics but also of the eco-tour site plan. And the entire use and management subject is different in each area.

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The investigation of adsorption properties of filter media for removal efficiency of nitrogen, phosphorus using experimental and density functional theory (실험 및 밀도범함수이론을 이용한 질소, 인 저감 효과 분석을 위한 여재의 흡착 특성 연구)

  • Kim, Taeyoon;Kwon, Yongju;Kang, Choonghyun;Kim, Jongyoung;Shin, Hyun Suk;Kwon, Soonchul;Cha, Sung Min
    • Journal of Wetlands Research
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    • v.20 no.3
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    • pp.263-271
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    • 2018
  • In this study, we analyzed the removal efficiency of ammonia nitrogen and phosphate dependant on the column depths using various absorbents such as zeolite silica sand, and activated carbon through the column test. In addition, we analyzed electrochemical adsorption behaviors of ammonia nitrogen and phosphate through the quantum mechanical calculation based on density functional theory calculation. Experimental results represent the removal efficiency of ammonia nitrogen and phosphate are zeolite > activated carbon > silica sand, and activated carbon > zeolite > silica sand, respectively. Zeolite shows high adsorption property for ammonia nitrogen over 90%, regardless of the column depth, while activated carbon exhibits high adsorption property for both ammonia nitrogen and phosphate as the column depth for filter media increases. Theoretical findings using DFT calculation for the adsorption behaviors of adsorbents (activated carbon and silica sand) and nutrients ($PO_4{^{3-}}$, $NH_4{^{+}}$) show that activated carbon represented narrower HOMO-LUMO band gap with high adsorption energy, and even more favorable environment for electron adsorption than silica sand, which leads to the effective removal of nutrients.

Trend Analysis of Water Quality in Dongjin River Watershed (동진강 유역의 수질 경향 분석에 관한 연구)

  • Lee, Hye-Won;Park, Seok-Soon
    • Korean Journal of Ecology and Environment
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    • v.42 no.1
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    • pp.39-47
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    • 2009
  • Spatial and temporal analysis of water quality was performed for eleven monitoring stations in Dongjin River watershed in order to determine the trends of monthly water quality. The monthly water quality data of biochemical oxygen demand (BOD), total nitrogen (TN) and total phosphorus (TP) during $1995{\sim}2004$, were analyzed utilizing Seasonal Mann-Kendall test, LOWESS and three-dimensional graphic approaches. The results indicated that BOD and TN concentrations had the downward trend, but TP showed the upward trend, especially in Gobucheon. This numerical and graphic analysis is the useful tool to analyze the long-term trend of water quality in a large river system.

Analysis of Drying Streams Characteristics in Mankyung Watershed (만경강유역 하천의 건천화 특성분석 연구)

  • Kim, Se Min;Kim, kyung Oh;Lee, Yun Jun;Park, Young Ki
    • Proceedings of the Korea Water Resources Association Conference
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    • 2020.06a
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    • pp.316-316
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    • 2020
  • 1970년대 이후 급속한 경제성장과 함께 도시화와 산업구조의 변화로 인간 활동과 밀접한 관계를 맺고 있는 수환경은 크게 훼손되어 왔다. 특히 인간 활동으로 인한 대량 생산과 소비는 하천의 자정작용을 초과하는 오염물질을 배출하고 오염된 하천은 본래 기능을 상실하였으며 각종 생활 오·폐수의 배수구로서의 역할이 부여되어 대부분 복개되기에 이르렀다. 이처럼 현재 우리나라의 하천은 고유의 기능인 용수원으로의 기능과 도시민의 휴식 및 친수공간으로서의 기능을 상실하였으며 중소하천의 건천화에 따른 하천 유지유량의 부족은 하천을 중심으로한 각종 용수의 부족, 수질 오염의 증가, 수변환경 친수기능 상실 등의 문제를 초래하고 있다. 중소하천의 건천화현상은 2000년대 이후 계속 증가, 진행되어 소하천뿐만 아니라 지방하천도 이미 메마르고 있는 상태이며 이로 인한 2차적 비용증가 등 경제적인 측면의 손실도 매년 심해지고 있어 건천화에 대한 원인 규명과 방지책에 대한 연구가 시급한 실정이다. 특히 새만금유역은 농업용수 사용이 많은 유역의 특성상 하천의 건천화 문제가 지적되었으나, 대부분 새만금유역의 용수이용체계 등에 연구가 추진되어 주로 농업용수 이용실태와 수질측정을 위주로 하고 있으며, 건천화의 실태와 원인, 그리고 건천화로 인한 물환경의 영향 등에 대해 조사된 바가 없다. 따라서 본 연구는 만경강유역 하천에 대하여 대조하천, 도시하천, 준도시하천, 농업하천으로 대표지점을 선정하여 현장조사와 유역모델링을 통해 건천화의 원인별 기여율을 파악하였고, 만경강유역의 건천화 규모를 추정하였다. 건천화 원인을 평가하기 위해 유역 내 인위적인 물이용이 없는 상태인 기준유량(자연유량)을 산정하였고, 댐 및 방류량의 영향, 하수처리수 유입에 의한 영향, 수자원이용에 의한 영향, 수리구조물(수자원이용)에 의한 영향의 조건을 고려하였으며 건천화 평가지수를 활용하여 대상하천 소유역의 건천화 현황을 파악하였다. 또한 분석된 결과를 토대로 만경강유역의 토지이용도를 고려하여 만경강유역의 건천화 규모를 추정하였다. 분석결과, 수리구조물(수자원이용)에 의한 영향이 25.5%, 수자원이용에 의한 영향이 13.9%, 방류량에 의한 영향이 12.3%, 하수처리수 유입에 의한 영향이 6.54%로 나타났으며, 수리구조물(수자원 이용)에 의한 영향이 가장 크게 평가되었고, 하수처리수 유입에 의한 영향이 가장 작은 것으로 평가되었다. 이러한 연구결과는 향후 하천의 건천화현상에 대한 원인을 규명하고 방지하기 위한 대책 수립에 필요한 기초자료로 활용이 가능할 것으로 판단된다.

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Water intake and oral disease symptoms in adolescents : a cross-sectional study conducted in Korea in 2021 (우리나라 청소년의 수분 섭취에 따른 구강질환 증상 : 2021년 청소년온라인행태조사 자료를 이용한 단면연구)

  • So-Yeong Kim;Sun-A Lim
    • Journal of Korean society of Dental Hygiene
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    • v.23 no.5
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    • pp.343-350
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    • 2023
  • Objectives: Water constitutes a majority of the human body and is essential for health. In addition, water intake can prevent dental caries by improving salivary lubrication and self-cleaning. This study aimed to determine the relationship between the amount of daily water intake and the symptoms of oral disease in Korean adolescents. Methods: We used data from the Korea Youth Risk Behavior Web-based Survey (KYRBS), conducted in Korea in 2021, and identified the relationship between daily water intake and oral disease symptoms in Korean adolescents. KYRBS is a nationwide cross-sectional survey conducted by the Korea Disease Control and Prevention Agency (KDCA), and a total of 54,848 participants were included in this study. Results: After adjusting for confounding factors, logistic regression analysis showed that tooth pain was more often experienced by those who drank less than two cups of water per day (odds ratio [OR]: 1.14; 95% confidence interval [CI]: 1.01-1.30) than those who drank five or more cups of water per day. Conclusions: A low daily water intake is associated with tooth pain, a symptom of dental caries. The results of our study suggest that increasing water intake may reduce dental caries. Therefore, adequate water intake may help prevent dental caries.

A Study on the Characteristics of Water Pollution in Rural Areas (농촌유역(農村流域)에서의 수질오염(水質汚染) 특성(特性)에 관한 연구(硏究))

  • Kim, Han-Tea;Kwun, Soon-Kuk
    • Korean Journal of Environmental Agriculture
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    • v.12 no.2
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    • pp.129-143
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    • 1993
  • The objective of this study is to understand the status of the water pollution in rural areas and to furnish a basic material for the management of the water pollution in rural areas. For this purpose, the Bokha river basin, Ichon-Gun, Kyungki-Do considering as a typical agricultural area was selected as a representative experimental watershed. The characteristics of water pollution in streams of the Bokha river basin was revealed by investigating and analyzing data collected for the source of pollution, water qualities in reaches of the stream, the degree of contribution to the river contamination by pollution mass produced from each source, and the status of the self-purification at the main stream. The most important source of the water pollution in investigated watershed was livestock, and the next important one were in the order of population, land use, and industry. The water quality of the Bokha river was relatively favorable judging from the BOD and COD concentration, however since the concentration of T-N and T-P showed significantly large values, it was concluded that the river was seriously contaminated by the nutrient material. The main cause of the river contamination was proved due to livestock waste. For the T-N, both land use and livestock were much more contributied to the pollution than any other source, which characterized the typical water pollution of rural areas. Run-off ratios for the Bokha river tributaries to the main stream were changed according to the similar trend to the variation of discharges in the branch streams. For the value of the self-purification constant at the main stream, it showed smaller value in the downstream reach than the middle-stream and upstream reaches, where could possibly have smaller reoxidation action due to slower velocity and deeper water depth.

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Appraising the Interface Features of Web Search Engines Based on User-defined Relevance Criteria (이용자정의형 적합성 기준을 토대로 한 웹검색엔진 인터페이스 평가)

  • Kim, Yang-Woo
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.22 no.1
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    • pp.247-262
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    • 2011
  • Although research has shown a significant amount of work identifying various dimensions of relevance along with exhaustive lists of relevance criteria, there seem to have been less effort to apply the findings to improve actual systems design. Based on this assumption, this paper investigates to what extent those relevance criteria have been incorporated into the interface features of major commercial Web search engines, suggesting what can/should be done more. Before stepping into the actual system features, this paper compares recent relevance research in Information Science with other human factor studies both in Information Science and its neighboring discipline (HCI), as an attempt to identify studies that are conceptually similar to the relevance research, but not named as such way. Similarities and differences between these studies are presented. Recommendations suggested to support applicable interface features include: 1) further personalization of interface designs; 2) author-supplied meta tags for the Web contents; and 3) extensions of beyond-topical representations based on link structure.