• Proceedings of the KIEE Conference
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• 2008.10b
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• pp.131-132
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• 2008

본 연구에서는 백서(SD rat)을 통하여 출혈량을 제어하여, 일정만 프로토클 내에서 통합 시스템으로 생리적 데이터를 획득하고, 출혈량에 따른 생리적 변화를 관찰하는데 목적이 있나 외상 환자의 사망 원인 중에서 높이 차지하고 있는 출혈성 쇼크의 효과석인 조기 피로 및 치료 효과 예후의 객관적 판정에 도움을 주고자, 컨트롤이 용이한 백서 11마리로부터 출혈성 쇼크와 상관관계가 높다고 알려진 자율 신경계의 생체 신호 변화 특성인 심전도, 혈압, 체온, 호흡 등의 계측 방법으로 측정하고 정량적으로 분석하였다. 그 결과 출혈전과 출혈중, 출혈후 각각의 생체 신호 변화를 살펴보았으며, 호흡수와 심박수, 심박변이도의 변화를 알 수 있었다.

• Proceedings of the KOSOMBE Conference
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• v.1997 no.11
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• pp.443-446
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• 1997

HRV(heart rate variability) is the time series data of R-R interval time duration based on ECGs. Power spectral analysis of HRV has recently been used to define the activity of ANS(autonomic nervous system). In this study, 14 rats were divided into two groups, sympathectomy and vagotomy. During the experiments, ECGs of rats were collected three times at each experimental conditions or the duration of 5 minutes, where sampling frequency was set at 2KHz. After the application of the Berger's Serires algorithm to ECG raw data, power spectrum of HRV was obtained via FFT. Results showed that HF/LF were increased or the sympathectomy group and decreased or the vagotomy group. It implies that the variations in HF/LF components could be used or the ANS function classification.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.64 no.8
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• pp.1240-1245
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• 2015

The purpose of this paper is to investigate the autonomic nervous system activity in various ambient temperatures. To evaluate autonomic function, we use the frequency domain analysis of heart rate variability such as FFT(fast fourier transformation), AR(Auto-Regressive) model and Lomb-Scargle peridogram. HRV(heart rate variability) is calculated by using ECG recorded from 3 different temperature room which temperature is controlled in 18℃(low), 25℃(mid) and 38℃(high), respectively. Totally 22 subjects were participated in the experiment. In the results, the most significant autonomic changes caused by temperature load were found in the HF(high frequency) component of FFT and AR model. And the HF power is decreased by increasing temperature. Significance level was increased by increasing the difference of temperatures.

• Tuberculosis and Respiratory Diseases
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• v.45 no.2
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• pp.404-415
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• 1998

Background: Sleep apnea syndrome, which occurs in 1~4 % of the adult population, frequently has different cardiovascular complications such as hypertension, ischemic heart disease, cardiac arrythmia as well as sleep-wake disorder such as excessive daytime hypersomnolence or insomnia. Mortality and vascular morbidity are reported to be significantly higher in sleep apnea syndrome patients than in normal population. According to the recent studies, autonomic dysfunction as well as hypoxemia, hypercapneic acidosis, and increased respiratory effort, may playa role in the high prevalence of cardiovascular complications in patients with sleep apnea syndrome. However the cause and mechanism of autonomic neuropathy in patients with sleep apnea syndrome are not well understood. We studied the existence of autonomic neuropathy in patients with sleep apnea syndrome and factors which influence the pathogenesis of autonomic neuropathy. Method: We used the cardiovascular autonomic neuropathy(CAN) test as a method for evaluation of autonomic neuropathy. The subjects of this study were 20 patients who diagnosed sleep apnea syndrome by polysomnography and 15 persons who were normal by polysomnography. Results: Body mass index and resting systolic blood pressure were higher in sleep apnea group than control group. Apnea index(Al), respiratory disturbance index(RDI) and snoring time percentage were significantly higher in sleep apnea group compared with control group. But there were no significant differences in saturation of oxygen and sleep efficiency in two groups. In the cardiac autonomic neuropathy test, the valsalva ratio was significantly low in sleep apnea group compared with control group but other tests had no differences between two groups. The CAN scores and corrected QT(QTc) interval were calculated significantly higher in sleep apnea group, but there were no significant correlations between CAN scores and QTc interval. There were no significant data of polysomnography to correlate to the CAN score. It meant that the autonomic neuropathy in patients with sleep apnea was affected by other multiple factors. Conclusion: The cardiovascular autonomic neuropathy test was a useful method for the evaluation of autonomic neuropathy in patients with sleep apnea syndrome and abnormalities of cardiovascular autonomic neuropathy were observed in patients with sleep apnea syndrome. However, we failed to define the factors that influence the pathogenesis of autonomic neuropathy of sleep apnea syndrome. This study warrants futher investigations in order to define the pathogenesis of autonomic neuropathy in patients with sleep apnea syndrome.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.47 no.2
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• pp.43-49
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• 2010

Autonomic nervous system (ANS) acts as a control system functioning largely below the level of consciousness, and controls visceral functions. The activity of the ANS has been assessed by means of the heart rate variability (HRV). It has been reported that HRV is dependent on sex, age, body mass index, and smoking, etc. However, the effects of posture and sleep deprivation on HRV have rarely been reported. Objective of our work was to find out which posture is appropriate for stable HRV. We measured the number of sleep deprivation and HRV using power spectrum in six stages for 30 minutes. Increased low frequency (LF) power and high frequency (HF) power indicate enhanced sympathetic and parasympathetic activity, respectively. We determined the LF/HF ratio to minimize individual difference. It was found that sleep deprivation by awakening up subjects was affected by posture, which resulted in changes of LF/HF. Although LF/HF varied with time, it was more stable in sitting than in supine. In conclusion, we recommend sitting posture when measuring HRV because of less sleep deprivation resulting in less variation in LF/HF.

• Korean Journal of Acupuncture
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• v.31 no.3
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• pp.136-145
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• 2014

Objectives : The purpose of this randomized, placebo-controlled, cross-over trial was to examine how acupuncture treatment at Shinmun(HT7) affects the brain activity and the autonomic nervous system(ANS), using electroencephalograms(EEG) and heart rate variability(HRV). Methods : Eighteen healthy volunteers participated in two separate experiments: in each experiment, either real acupuncture(RA) or non-penetrating sham acupuncture(SA) was applied at HT7 in random sequences to each person. The EEG and HRV measurements were conducted simultaneously before and during the acupuncture stimulation for 5 minutes, respectively. Resulting EEG and HRV parameters were compared between RA and SA groups. To assess differences according to the stress levels for participants, subgroup analysis was performed based on the results of the stress response index questionnaire. Results : In the results, acupuncture stimulation at HT7 increased ${\alpha}$ band in EEG. In the HRV analysis, heart rate was decreased significantly but HF and RMS-SD were increased in the RA group, compared with those of the SA group. In the subgroup analysis by stress level, participants in the RA group with high stress exhibited an increased in ${\alpha}$ band in their EEG while the low stress participants showed decrease or little increase in the band. For the SA group, ${\alpha}$ band reported relatively moderate changes in all channels. Conclusions : Our results showed that acupuncture induces changes in brain activation and the ANS. Acupuncture was related to the activation of the parasympathetic nervous system. The brain activities of the participants were different depending on the stress level.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 1999.11a
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• pp.362-367
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• 1999

본 연구에서는 정신분열증 환자들이 정서상태를 개념화하고 얼굴표정을 통하여 타인의 정서 상태를 판단하는 과정을 정상인과 비교하였다. 연구1에서는 만 19세-46세의 정신분열병 환자 19명에게 정서 관련 형용사 15개로 구성된 105개의 형용사 쌍에 대하여 유사성을 평정하도록 하여 MDS로 분석한 결과, 쾌/불쾌와 각성의 두 차원이 일관되게 보고되고 있는 정상집단과는 달리 정신분열병 집단의 자료에서는 쾌/불쾌 차원만이 뚜렷하게 나타나고 각성 차원은 얻어지지 않았다. 연구 2에서는 다양한 정서를 표현한 얼굴 사진 28개를 정신분열병 환자 30명과 대학생 31명에게 제시하고 각 사진의 인물이 경험하고 있는 내적 상태를 쾌/불쾌와 각성의 두 차원에 대하여 각각 7점 척도로 평정하도록 한 결과 정신분열병 집단은 대학생 집단에 비하여 쾌/불쾌 차원에서는 보다 긍정적으로 평정하는 경향이, 각성 차원에서는 상대적으로 낮게 평가하는 경향을 나타냈다. 특히 부정적이고 각성 수준이 높은 내적 상태를 표현하는 사진 자극에 대하여 정신분열병 환자 집단이 각성수준을 과소평가하는 경향이 두드러지게 나타났다. 이와 같은 결과를 종합하여 볼 때, 정신분열병 환자들은 정서상태의 개념화 과정에서 각성 차원에 대하여 상대적으로 낮은 민감도를 보이고 있으며, 특히 부정적인 정서상태를 표현하는 얼굴들에 대란 판단에서는 각성 차원을 과소평가하여 높은 각성수준을 나타내는 표정과 낮은 각성수준을 변별하는데 어려움을 보이는 것으로 해석될 수 있다. 본 연구의 결과는 정신분열병 환자들은 자율신경계의 높은 각성 수준으로 인하여 각성 수준을 더 높일 가능성이 있는 자극을 회피하는 경향이 있다는 Mednick의 가설과 일관되는 결과로 이들의 각성 수준에 대한 낮은 민감도는 방어적인 회피성향의 지속에 따른 둔감화의 결과로 해석될 수 있다. 효과는 GSR를 비롯한 자율신경계지표에서 잘 반영되었다.^2$=.792가 되었다. 설명되는 누적분산값은 67.18%였다.주관적 평가의 결과와 객관적 평가 결과를 이용해 마직물의 태를 평가하는 산출식을 제시하였다. 태 평가치의 경우 16가지 특성치를 모두 넣는 방법과 stepwise 방법, 또 Kawabatark 사용한 순차적 군 회귀법의 세가지 방법의 회귀식 중 16가지 특성치를 모두 넣는 방법의 결정계수가 가장 높았다.tosterone농도는 107.7$\pm$12.0 pmol／l이었고, 남성의 타액내 농도는 274.2$\pm$22.1 pmol／l이었다. 이상의 결과로 보아 본 연구에서 정립된 EIA 방법은 RIA를 대신하여 소규모의 실험실에서도 활용할 수 있을 것으로 사려된다.또한 상실기 이후 배아에서 합성되며, 발생시기에 따라 그 영향이 다르고 팽창과 부화에 관여하는 것으로 사료된다. 더욱이, 조선의 ${\ulcorner}$구성교육${\lrcorner}$이 조선총독부의 관리하에서 실행되었다는 것을, 당시의 사범학교를 중심으로 한 교육조직을 기술한 문헌에 의해 규명시켰다.nd of letter design which represents -natural objects and was popular at the time of Yukjo Dynasty, and there are some documents of that period left both in Japan and Korea. "Hyojedo" in Korea is supposed to have been influenced by the letter design. Asite- is also considered to have been "Japanese Lett

• 재활복지
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• v.20 no.3
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• pp.105-124
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• 2016

The This study aims to verify the causal relationship among physically disability persons participation in exercise, heart rate variance, and facial expression recognition. To achieve such research goal, this study targeted 139 physically disability persons and as for sampling, purposive sampling method was applied. After visiting a sporting stadium and club facilities that sporting events were held and explaining the purpose of the research in detail, only with those who agreed to participate in the research, their heart rate variance and facial emotion awareness were measured. With the results of measurement, mean value, standard deviation, correlation analysis, and structural equating model were analyzed, and the results are as follows. The quantity of exercise positively affected sympathetic activity and parasympathetic activity of autonomic nervous system. Exercise history of physically disability persons was found to have a positive influence on LF/HF, and it had a negative influence on parasympathetic activity. Sympathetic activity of physically disability persons turned out to have a positive effect on the recognition of the emotion, happiness, while the quantity of exercise had a negative influence on the recognition of the emotion, sadness. These findings were discussed and how those mechanisms that are relevant to the autonomic nervous system, facial expression recognition of physical disability persons.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 1999.03a
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• pp.163-167
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• 1999

사회와 생활수준의 발달로 인간은 자연환경하에서 생활보다 인공적 환경하에서의 생활이 증가하게 되었다. 따라서 인간은 쾌적한 생활공간을 요구하게 되었고 이를 위한 온열환경에 대한 연구가 진행되어져 왔다. 이러한 생활공간에서의 쾌적한 온열환경에 영향을 주는 물리적 요인으로는 온도와 습도 그리고 기류 등이 있다. 또한 온열환경에 대한 인간의 감성적 측면도 쾌적한 온열환경을 결정하는데 중요한 역할을 한다. 본 연구에서는 겨울철 대류난방시 인간에게 가장 쾌적한 환경을 제시할 수 있는 기류 속도의 범위를 찾고, 이를 평가하는데 객관적인 지표를 설정하기 위해 온도에 따른 기류조건을 제시하고, HRV 분석을 통하여 인체의 자율신경계의 변화를 관찰하였다. 실험결과 18$^{\circ}C$, 21$^{\circ}C$, 24$^{\circ}C$ 각각의 온도에서 draft를 초래하지 않는 0.15m/sec의 기류속도일 때 가장 높은 MF/(LF+HF) 값을 보여 쾌적한 기류조건으로 나타났고 이는 쾌불쾌감신고(CSV)와 동일한 결과를 나타내었다. 이러한 심전도 신호를 통한 HRV 분석은 기류조건에 따른 온열쾌적성의 평가에도 객관적이고 신뢰성 있는 지표로 제시될 수 있을 것이다. 또한 다른 환경하에서의 감성평가 척도로도 이용될 수 있을 것이라고 생각되어진다.

• Science of Emotion and Sensibility
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• v.9 no.2
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• pp.111-118
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• 2006

The purpose of the study is to examine the effects of the positive menial stress, eustress, on autonomic nervous system(ANS) and human health. For this, we analyzed heart rate variability(HRV) parameters, the most promising markers of ANS function to assess the changes of emotional and physiological states of human body. We measured HRV Signal of World Cup group(281 male subjects: $29.8{\pm}5.6yr$., 187 female subjects: $29.0{\pm}5.4yr$.) in two stadiums at least an hour before the game during '2002 FIFA World Cup Korea/Japan' event. We also measured control group's(331 male subjects: $30.9{\pm}4.7 yr$., 344 female subjects: $30.2{\pm}5.2 yr$.) in the health promotion centers in two university hospitals at least a month before and after the world cup event period. Considering physiological differences between males and females, the data analysis was applied to 'male group' and 'female group' separately. As a result, some tendency was observed that is different from what we have known as the stress reaction. In general, all parameter values except that of mean heart rate tend to decrease under stressed condition. However, under eustressed condition, both heart rate and standard deviation of the Normal to Normal intervals(SDNN) were higher then those of normal condition(p<0.05). Especially, in case of female group, contrary to distressed condition, every frequency-domain powers showed tile higher value(p<0.05, p<0.001). Considering that decrease of HRV indicates the loss of one's health, the increase of SDNN and frequency parameters means that homeostasis control mechanism of ANS is functioning positively. Accordingly, induction of eustress from international sports event may affect positively to the people's health.