• Title/Summary/Keyword: 자연변이

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Disparity Estimation using a Region-Dividing Technique and Edge-preserving Regularization (영역 분할 기법과 경계 보존 변이 평활화를 이용한 스테레오 영상의 변이 추정)

  • 김한성;손광훈
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.41 no.6
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    • pp.25-32
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    • 2004
  • We propose a hierarchical disparity estimation algorithm with edge-preserving energy-based regularization. Initial disparity vectors are obtained from downsampled stereo images using a feature-based region-dividing disparity estimation technique. Dense disparities are estimated from these initial vectors with shape-adaptive windows in full resolution images. Finally, the vector fields are regularized with the minimization of the energy functional which considers both fidelity and smoothness of the fields. The first two steps provide highly reliable disparity vectors, so that local minimum problem can be avoided in regularization step. The proposed algorithm generates accurate disparity map which is smooth inside objects while preserving its discontinuities in boundaries. Experimental results are presented to illustrate the capabilities of the proposed disparity estimation technique.

Development of Bacillus thuringensis var. kurstaki NRD 6-Stu 1 by Site-Directed Mutagenesis (위치지정 변이기법을 이용한 Bacillus thuringiensis var. kurstaki NRD 6-Stu 1의 육성)

  • Lee, Jong-Su
    • The Journal of Natural Sciences
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    • v.6 no.1
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    • pp.41-48
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    • 1993
  • A cloned delta-endotoxin gene from Bacillus thuringiensis var. kurstaki NRD 6 was mutated at N-terminal toxic portion of the protoxin by site-directed mutagenesis. A Stu 1 restriction site was created in protoxin region of the mutant B.t.kurstaki NRD 6-Stu 1 which changed A to C in 177 region of the protoxin(silent mutation). Antigenic property of crystalline inclusion (delta-endotoxin) of the mutant was no difference to intact strain by the western blot analysis and its toxidity threshold value was also showed 0.015~0.030ng against Choristoneura femiferana-1 insect, similar with 0.01~0.024ng of parent strain, but stronger than that of B.t.kurstaki NRD 5 (500~1000ng) and B.t.kurstaki NRD 4(none toxic).

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Analysis of deleterious genes in natural and experimental populations of Drosophila melanogaster (Drosophila melanogaster 자연 및 실험집단내의 유해유전자 분석)

  • 이원호;최우영;권은전;박희정
    • Journal of Life Science
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    • v.13 no.3
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    • pp.252-257
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    • 2003
  • The genetic variabilities of second chromosomes of Drosophila melanogaster concealed in Busan natural and experimental populations have been analyzed by the Cy//Pm method. The experimental population was composed of D. melanogaster which had the lethal-free second chromosome, collected Sasang natural population in 1982. The frequencies of deleterious genes were estimated to be 14.3∼25.4% in Busan natural population and 26.5∼27.2% in experimental population. The allelism rates in lethal genes isolated from the natural and experimental populations were calculated to be about 0.76% and 9.76∼14.17%, respectively. The value of elimination by the frequencies of deleterious genes and allelism rate was 0.0106and the effective population size estimated to be about 430 flies at the 6570 days population.

Natural variation of functional components between Korean maize types (국내 옥수수 품종에 따른 기능성 성분의 자연 변이 분석)

  • Jung-Won Jung;Myeong-Ji Kim;Imran Muhammad;Eun-Ha Kim;Soo-Yun Park;Tae-Young Oh;Young-Sam Go;Moon-Jong Kim;Sang-Gu Lee;Seonwoo Oh;Hyoun-Min Park
    • Journal of Applied Biological Chemistry
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    • v.66
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    • pp.484-491
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    • 2023
  • Maize is one of the major crops consumed in worldwide, which nutrients accounts for a large amount of starch, but also functional components, and phenolic acid is known to have a high content. Maize is divided into waxy maize, sweet maize, and normal maize with its shape and use, therefore there is also a difference in nutritional composition. This study was conducted to analyze the content of functional components according to the type of maize and to produce natural variation data in consideration of environmental factors. 3 shapes of maize (waxy maize, sweet maize, and normal maize) samples cultivated in 3 regions (Suwon, Daegu, and Hongcheon) were analyzed using HPLC and GC-TOF-MS. Comparing with type through ANOVA, multivariate statistical analysis, Pearson correlation analysis, 28 components, including carotenoids and tocopherols, showed significant differences among a total of 32 components (p <0.05), 15 of them showed very significant differences (p <0.001). When comparing with regions, 15 components showed significant differences and only vanillate, syringate, C23-ol of them showed most significant differences (p <0.001). As a result of principal component analysis, cluster classification was distinguished by shape than by region, with α-carotene, cholesterol for waxy maize, vanillate and stigmasterol for sweet maize, lutein and β-carotene for normal maize had a great effect on cluster formation. It suggests that the content of functional components is more affected by genetic factors than environmental factors.

SARS-CoV-2 Variant Prediction Algorithm Using the Protein-Protein Interaction Model with BERT Mask-Filling (BERT Mask-Filling과 단백질-단백질 상호작용 모델을 이용한 SARS-CoV-2 변이 예측 알고리즘)

  • Kong, Hyunseung
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2021.07a
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    • pp.283-284
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    • 2021
  • 최근 SARS-CoV-2 백신들의 예방접종이 진행됨에 따라 코로나 19 팬데믹의 종결이 예상되고 있다. 하지만 계속해서 출현 중인 변종 바이러스들은 팬데믹 종결의 위험요소로 남아있다. 본 논문에서는 사전학습된 단백질 BERT와 단백질-단백질 상호작용 모델을 활용한 SARS-CoV-2 스파이크 단백질의 변이 예측 분석 알고리즘을 제안한다. 제안하는 기술은 변이 단백질 서열의 예측과 변이 단백질과 human ACE2 수용체의 친화도에 따른 자연선택으로 이루어진다. 이를 통해 시간이 지나며 나타날 수 있는 변종 바이러스들을 시뮬레이션 할 수 있어 변종 바이러스들의 해결에 기여할 것으로 기대된다.

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Hierarchical Disparity Estimation for Image Synthesis in Stereo Mixed Reality (스테레오 혼합 현실 영상 합성을 위한 계층적 변이 추정)

  • 김한성;최승철;손광훈
    • Journal of Broadcast Engineering
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    • v.7 no.3
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    • pp.229-237
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    • 2002
  • Natural synthesis of real and virtual images is a key technology in mixed reality. For this purpose, we propose an efficient dense disparity estimation algorithm and a synthesis algorithm considering features of stereo images. Dense disparities are estimated hierarchically from the low to high resolution images. In the process, the region-dividing-bidirectional-matching algorithm makes matching process efficient and keeps the reliability of the estimated disparities, and dense disparities are assigned considering edge information. finally, mixed reality stereo images are synthesized by comparing depth data of real and virtual Images. Computer simulation shows that the proposed algorithms estimate very stable disparity vectors with sharp edge and synthesize natural stereo mixed reality images.

Effects of Heart Rate Variability after Visiting the Gotjawal Forest in Jeju (제주 곶자왈숲 삼림욕 후에 심박동변이에 미친 영향)

  • Sin, Bangsik;Lee, Hyung H.;Lee, Keun Kwang
    • Journal of Naturopathy
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    • v.7 no.1
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    • pp.1-9
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    • 2018
  • The purpose of this study is to statistically investigate the changes in mean differences of the vascular age types and index, heart beating, vessel elasticity, diastolic reserves contents measured by the fingertip plethysmogram before and after the subjects (49 people) visit the Gotjawal forest for two hours. While there is no significant change in the mean differences of vascular age types and index, heart beating, diastolic reserves contents in the control group before and after the visit, the differences in the test groups gets higher than the control group and shows a significant difference. Moreover, the variance analyses of the mean values of the contents shows a significant change after the visit. There is no significant change in the values of vessel elasticity changes between the groups after the visit, but the change of values is significant in the within group, and it is not significant between group by variance analysis. The differences of the heart beating was insignificant in the within group, but significant between group after the visit. In conclusion this study proves the effects of forest bathing, because the HRV index significantly improved after the bathing. Therefore the b-c-d-e/a ratio may be useful for evaluation of HRV.

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발효유의 종균 L. casei YIT 9018의 자연돌연변이주의 발생 빈도 및 그 특성에 관한 연구

  • 김동운;차송일;강국희
    • Proceedings of the Korean Society for Applied Microbiology Conference
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    • 1986.12a
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    • pp.513.3-514
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    • 1986
  • 유산균을 종균으로 하여 유제품을 만드는 경우에 종균의 취급관리는 매우 중요한 일이다. 종균을 취급하는 과정에서 어떤 원인으로 인하여 종균의 활력 특히 산생성력이 감퇴되어 종균으로 사용할 수 없는 경우가 발생한다. 이러한 경우의 원인을 분석하여 그 예방책을 수립하기 위한 기초 연구로써 발효유의 종균으로 사용하고 있는 L. casei YIT9018의 spontaneous lac 변이주의 발생빈도 및 이러한 Lac 변이주의 특성을 검토하였다. parent colony에서의 Lac의 발생빈도는 MRS 배지에서 400 coloney중에서 1개, 10% 환원 탈지분유에서는 984개중 1개의 배율로 나타났다. 분리된 Lac 변이주중에는 Lac Gal도 검출되었다 대부분의 Lac를 탈지유배지에 배양할 경우 10일이 지나면 우유를 응고시켰으나 Lac Gal는 30일이 지난뒤에 응고시켰다. Lac변이주를 MRS-lactose 배지의 plate에 도말하여 배양하면 4일 이후부터는 revertant가 나타났으나 Lac Gal Cell에서는 인정되지 않았다. 얻어진 Lac 변이주의 plasmid를 분리하여 parent와 비교한 결과 plasmid DNA가 소실되었음을 확인하였다.

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Motion Vector and Disparity Vector Prediction for Multi-view Video Coding (다시점 동영상 부호화를 위한 움직임 벡터 및 변이 벡터 예측 기법)

  • Lee, Seo-Young;Shin, Kwang-Mu;Kim, Sung-Min;Chung, Ki-Dong
    • Proceedings of the Korean Information Science Society Conference
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    • 2007.10d
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    • pp.560-563
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    • 2007
  • 다시점 영상은 관찰자가 원하는 시점을 선택할 수 있고, 자연스러운 입체감을 제공한다. 하지만 카메라의 수가 증가함에 따라 데이터양이 늘어나는 단점이 있다. 본 논문은 시.공간적 상관성을 고려한 시점 간 움직임 벡터 예측 기법을 제안한다. 인접한 시점의 영상이 비슷한 움직임 정보를 가지는 특징을 이용해 현재 블록의 움직임 벡터의 예측간을 계산한다. 또한 시간적으로 연속한 프레임의 경우 비슷한 변이 벡터를 가지므로, 이전 프레임의 변이 벡터 정보를 현재 매크로블록의 변이벡터로 활용하는 방법을 제안한다.

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